| Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704) |
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| 08/21/2008 | WO2008019055A3 Processes for optical resolution of 1-phenyl-1,2,3,4-tetrahydroisoquinoline |
| 08/21/2008 | US20080200681 Processes for preparing palonosetron salts |
| 08/21/2008 | US20080200509 Utilizing such as 4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide against cancer growth |
| 08/20/2008 | EP1732547B1 Anti-hiv quinuclidine compounds |
| 08/20/2008 | CN101247853A Substituted indole compounds having NOS inhibitory activity |
| 08/20/2008 | CN101245063A Method for synthesizing cinchona alkaloids microwave radiation non-solvent |
| 08/14/2008 | WO2008096870A1 Aza-bridged-ring compound |
| 08/14/2008 | WO2008077357A3 A method for the preparation of solifenacin |
| 08/14/2008 | US20080194625 Tetrahydroquinoline derivatives as cannabinoid receptor modulators |
| 08/14/2008 | US20080194573 3-(Heteroaryl-Oxy)-2-Alkyl-1-Aza-Bicycloalkyl Derivatives As Alpha. 7-Nachrligands For TheTreatment Of Cns Diseases |
| 08/14/2008 | US20080194551 Acetylene Derivatives |
| 08/14/2008 | CA2678193A1 Aza-bridged-ring compound |
| 08/13/2008 | EP1955697A1 2-aminobenzamide derivative |
| 08/13/2008 | CN101239971A Biphenyl derivatives |
| 08/13/2008 | CN101239970A Biphenyl derivatives |
| 08/13/2008 | CN101239969A Biphenyl derivatives |
| 08/13/2008 | CN101239968A Biphenyl derivatives |
| 08/07/2008 | US20080188519 Novel azacyclic ethynyl derivatives |
| 08/07/2008 | US20080188518 5-Substituted Imidazoles |
| 08/07/2008 | US20080188489 Cell differentiation inducer |
| 08/06/2008 | EP1951691A1 Process for the preparation of n-triazinylammonium salts |
| 08/06/2008 | CN101238121A Fused bicycloheterocycle substituted quinuclidine derivatives |
| 08/05/2008 | US7408065 P2X7 receptor antagonists and their use |
| 08/05/2008 | US7407938 1,4-Diphenyl-3-(3-hydroxy-3-phenylpropyl)-2-azetidinones, e.g., 2,3,4,5,6-Pentahydroxyhexylamide of 4-(4-{4-[3-[3-(4-fluorophenyl)-3-hydroxypropyl]-2-(4-methoxyphenyl)-4-oxoazetidin-1-y]lbenzylcarbamoyl}phenoxy)benzoic acid; antilipemic agents that have intestinal absorption of less than 10%, |
| 07/31/2008 | WO2008073687A3 Compounds and compositions as protein kinase inhibitors |
| 07/31/2008 | WO2008051539A3 Processes for preparing palonosetron salts |
| 07/31/2008 | WO2008019103A3 Solifenacin base forms and preparation thereof |
| 07/30/2008 | CN101230008A Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them |
| 07/24/2008 | US20080176890 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof |
| 07/23/2008 | EP1945636A2 Polymorphs of solifenacin intermediate |
| 07/23/2008 | CN100404533C New quinuclidine amide derivatives |
| 07/16/2008 | EP1943248A2 Solifenacin base forms and preparation thereof |
| 07/16/2008 | EP1506205B1 Novel azacyclic ethynyl derivatives |
| 07/16/2008 | CN101220067A Diphosphate salt of a 4 -substituted-9-deoxo-9a-aza-9a-homoerythromycin derivative and its pharmaceutical composition |
| 07/16/2008 | CN101220026A 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| 07/16/2008 | CN100402549C Bridged bicyclic serine protease inhibitors |
| 07/15/2008 | CA2421120C Quinolinone derivatives as tyrosine kinase inhibitors |
| 07/10/2008 | WO2008019057A3 Polymorphs of solifenacin intermediate |
| 07/09/2008 | EP1940833A1 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof |
| 07/09/2008 | EP1940832A1 Novel 1-aza bicycloalkyl derivatives for the treatment of psychotic and neurodegenerative disorders |
| 07/09/2008 | EP1332133B1 Metabotropic glutamate receptor antagonists |
| 07/08/2008 | US7396844 3-(4-amidinobenzoylamino)-4-[5-amidino-2-(2-carboxy-2-oxoethyl)phenoxy]butanoic acid; anticoagulant; blood coagulation factor X and thrombin inhibitor; cerebral infarction, thrombosis, embolism, transient ischemic attack (TIA) and subarachnoidal hemorrhage (vasospasm); ischemic heart diseases |
| 07/03/2008 | WO2008077357A2 A method for the preparation of solifenacin |
| 07/03/2008 | US20080161343 Sigma 2 Receptor Ligands and Therapeutic Uses Therefor |
| 07/02/2008 | EP1539166B1 Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders |
| 06/26/2008 | WO2008077089A1 Pyrrolidinanilines |
| 06/26/2008 | WO2008075005A1 Quinuclidinol derivatives as muscarinic receptor antagonists |
| 06/26/2008 | US20080154037 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof |
| 06/26/2008 | CA2672446A1 Quinuclidinol derivatives as muscarinic receptor antagonists |
| 06/25/2008 | EP1725552B1 New quaternized quinuclidine esters |
| 06/25/2008 | CN100396677C 2-thio-substituted imidazole derivatives and their use in pharmaceutics |
| 06/24/2008 | US7390790 Antilipemic agents; anticholesterol agents, for example, 2,3,4,5,6-Pentahydroxyhexylamide of 4-(4-{4-[3-[3-(4-fluorophenyl)-3-hydroxypropyl]-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]benzylcarbamoyl}phenoxy)benzoic acid |
| 06/19/2008 | WO2008051564A3 Crystalline forms of palonosetron hydrochloride |
| 06/12/2008 | US20080138287 3-substituted-2(arylalkyl)-1- azabicycloalkanes and methods of use thereof |
| 06/11/2008 | EP1930330A1 Pleuromutilin derivatives as antimicrobials |
| 06/11/2008 | CN101198604A NPY antagonists, preparation and use |
| 06/10/2008 | US7385059 3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators |
| 06/10/2008 | US7384954 3-Imidazol-1-yl-1-azabicyclo[2.2.2]octane; agonist, partial agonist, or antagonist of the alpha 7 nicotinic acetylcholine receptor; antidepressant, anxiolytic agent, cognition activator, neuroprotectant; radiolabel |
| 06/05/2008 | US20080132704 3-Substituted quinuclidines and their use |
| 06/04/2008 | EP1747198B1 Adamantyl pyrrolidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| 05/29/2008 | CA2670365A1 An improved process for the synthesis of solifenacin |
| 05/28/2008 | CN101186607A Method for synthesizing palonosetron hydrochloride |
| 05/28/2008 | CN100390178C Polycycloalkylpurines as adenosine receptor antagonists |
| 05/28/2008 | CN100390154C Quinoline and quinoxaline compounds as PDGF-receptor and/or LCK tyrosine kinase inhibitors |
| 05/27/2008 | US7378526 Cholinergic ligands at the nicotinic acetylcholine receptors; diseases related to the cholinergic system; neurodegenerative disorders; pain; antiinflammatory; diagnostic or monitoring tools using labelled forms; 3-Phenyletynyl-quinuclidin-2-ene |
| 05/22/2008 | WO2008059245A1 Quiniclidine derivatives of (hetero) arylcycloheptanecarboxylic acid as muscarinic receptor antagonists |
| 05/22/2008 | CA2669326A1 Quiniclidine derivatives of (hetero) arylcycloheptanecarboxylic acid as muscarinic receptor antagonists |
| 05/21/2008 | EP1923391A1 Substituted heterocyclic compounds, method for preparing same and pharmaceutical compositions containing them. |
| 05/20/2008 | US7375222 anti-dementia agent which uses a BEC 1 potassium channel inhibitor as the active ingredient; to improve learning disorder |
| 05/20/2008 | US7375110 Nicotinic cholinergic receptors modulators; pain, neurodegenerative diseases; neurotransmission dysfuctions; central and autonomic nervous systems disorders; 1'-(3-pyridyl)-spiro[1-azabicyclo[2.2.1]heptane-2,3'-pyrrolidine] |
| 05/15/2008 | WO2008056263A2 Quality control methods for oil-in-water emulsions containing squalene |
| 05/15/2008 | WO2008021339A3 Pyrrolidine and related derivatives useful as pr modulators |
| 05/15/2008 | US20080114171 Amorphous and crystalline forms of 1-azabicyclo[2.2.2]oct-3-yl-1-phenyl-3,4-dihydroisoquinoline-2-(1H)-carboxylate; stability, flowability, solubility |
| 05/15/2008 | US20080114028 Combining solifenacin, succinic acid, and a solvent; urinary antispasmodic; selective antagonist to the M(3)-receptor |
| 05/14/2008 | EP1919909A2 Synthetic methods and intermediates for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders |
| 05/13/2008 | CA2196995C Spiro-azabicyclic compounds useful in therapy |
| 05/08/2008 | US20080108609 Benzoxazole Carboxamides For Treating CINV and IBS-D |
| 05/08/2008 | US20080108600 Polycyclic Pyridines as Potassium Ion Channel Modulators |
| 05/07/2008 | EP1558600B1 Selected cgrp antagonists, method for production and use thereof as medicament |
| 05/01/2008 | US20080103170 Nicotinic Acetylcholine Receptor Ligands |
| 04/29/2008 | US7365070 Such as N-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-fluoro-benzoyl}-N'-butyl-guanidine; involuntary weight loss disorders |
| 04/29/2008 | CA2218887C Piperazino derivatives as neurokinin antagonists |
| 04/22/2008 | US7361678 Azole derivatives and fused bicyclic azole derivatives as therapeutic agents |
| 04/22/2008 | US7361668 Quinuclidine derivatives processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors |
| 04/17/2008 | WO2008019372A3 2-aminobenzoxazole carboxamides as 5ht3 modulators |
| 04/17/2008 | WO2007147374A3 Process for the preparation of solifenacin |
| 04/17/2008 | US20080090905 Antidiabetic agents; insulin resistance; dyslipidemias; dietetics |
| 04/17/2008 | US20080090828 insecticides for soil-borne insects, such as termites and white grubs; less costly and safer to use on crops; N-{4-[(4-{bis[4-(trifluoromethyl)phenyl]methylene}piperidyl)methyl]phenyl}ethoxycarboxamide, N-oxide |
| 04/16/2008 | CN101163669A Acetylene derivatives |
| 04/16/2008 | CN101161651A Method for preparing 3-amido quinine medically-acceptable salt |
| 04/15/2008 | US7358359 Antibacterial agents |
| 04/15/2008 | US7358260 Quinuclidine derivatives and medicinal compositions containing the same |
| 04/10/2008 | US20080085915 Emesis, dyspepsia, gastroparesis, constipation, gastroesophageal reflux, or post-operative ileus; stereoisomeric esterified cisapride analogs; side effect reduction of adverse events by avoiding the cytochrome P450 drug detoxification system |
| 04/09/2008 | CN101160308A Methods of treating cancer and related methods |
| 04/09/2008 | CN101160307A Benzoxazole carboxamides for treating cinv and ibs-d |
| 04/09/2008 | CN101157691A Production technique of hydrochloric acid palonosetron |
| 04/08/2008 | US7355046 Chronic obstructive pulmonary dusease; asthma |
| 04/08/2008 | US7354930 N-biarylamides |
| 04/03/2008 | WO2008019363A3 2-alkylbenzoxazole carboxamides as 5ht3 modulators |
| 04/03/2008 | US20080081911 Method for producing optically active quinuclidinols having one or more substituted groups at the 2-position |