Patents
Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704)
02/2007
02/20/2007US7179818 Substituted aminoquinuclidine compounds
02/20/2007US7179816 Chemical derivatives and their application as antitelomerase agents
02/20/2007US7179794 Antibiotics; bactericides
02/15/2007WO2007018738A2 Fused bicycloheterocycle substituted quinuclidine derivatives
02/15/2007US20070037984 Biphenyl derivatives
02/15/2007US20070037844 2-(1-Azabicyclo[2.2.2]oct-3-yl)-N-(7-bromo-1-benzothien-2-yl)acetamide hydrochloride; nicotinic receptor agonists; cognition activators; learning enhancement; nootropic agents; demetia; cholinergic agents; Alzheimer's disease; brain traumas; stroke; attention deficit disorder; schizophrenia
02/15/2007US20070037787 Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
02/15/2007CA2611674A1 Fused bicycloheterocycle substituted quinuclidine derivatives
02/14/2007EP1751150A2 Novel azabicyclic aryl derivatives
02/14/2007CN1914202A Process for preparation of 1-(2s,3s)-2-benzhydryl-n-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amine
02/14/2007CN1914201A 烟碱乙酰胆碱受体配体 Nicotinic acetylcholine receptor ligands
02/14/2007CN1914200A Nicotinic acetylcholine receptor ligands
02/14/2007CN1913884A Substituted benzazoles and methods of their use as inhibitors of RAF kinase
02/13/2007US7176242 N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives
02/13/2007US7176236 Water-soluble etoposide analogs and methods of use thereof
02/13/2007US7176219 Salts of quinuclidine derivative
02/13/2007US7176218 Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
02/13/2007US7176217 such as N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl]-2-azabicyclo[2.2.1]heptane-3-carboxamide, used in cosmetics or drugs as gelatinase inhibitors, for preventing skin aging or wrinkling; preventing diseases due to abnormal metabolism of tissue matrices such as arthritis, ulcers, metastasis or tumors
02/13/2007US7176198 1H-pyrazole and 1H-pyrrole-azabicyclic compounds for the treatment of disease
02/13/2007US7176194 Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
02/07/2007CN1298717C Quinuclidine carbamate derivatives and their use as M3 antigonists
02/06/2007US7173032 Antiproliferative agents for smooth muscle cells; antiinflammatory agents for endothelial cells; restenosis, atherosclerosis
01/2007
01/31/2007EP1747219A2 Muscarinic acetylcholine receptor antagonists field of the invention
01/31/2007EP1747198A1 Adamantyl pyrrolidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
01/31/2007CN1906172A Pyrazolyl derivatives in the form of drugs for treating acute or chronic neuronal regressions
01/30/2007US7169785 e.g., 2-{[4-(Cyclohexylmethyl-amino)-6-(3-fluoro-4-methoxy-phenylamino)-[1,35]triazin-2-ylamino]-methyl}-cyclopentanone; treating unwanted cellular proliferation, an inflammation mediated disease, or a hyperproliferative disease, or modulating a glycosidase enzyme
01/30/2007US7169784 Medical devices employing triazine compounds and compositions thereof
01/30/2007US7169774 Purification of natural, synthetic or semi-synthetic crude harringtonines by reverse phase chromatography and crystallization; solvent is water or lower alkanol, or an aqueous mixture of organic solvents; enantiomerically pure; industrial scale; leukemia chemotherapy
01/30/2007CA2307551C Pleuromutilin derivatives as antimicrobials
01/30/2007CA2228939C Didepsipeptide-based endoparasiticides, new didepsipeptides and process for preparing the same
01/25/2007US20070021386 Azole derivatives and fused bicyclic azole derivatives as therapeutic agents
01/24/2007EP1746093A1 Process for preparing substituted pyrimidines
01/24/2007EP1745019A1 Novel compounds of proline and morpholine derivatives
01/24/2007CN1902197A Improved aza-bridged-bicyclic amino acid derivatives as alpha4 integrin antagonists
01/18/2007US20070015788 N-(3-Aryl-3-substitutedphenylpropyl) piperidines or 8-azabicyclo[3.2.1]octanes that are additionally substituted with an optionally fused 5-member N-heterocycle; the compounds are modulators of CCR5 receptor activity and are used in treating diseases such as rheumatoid arthritis
01/18/2007US20070015732 Adenosine receptor antagonists and methods of making and using the same
01/17/2007EP1742909A2 Anionic-sweetener-based ionic liquids and methods of use thereof
01/17/2007CN1295221C Substituted heterocyclic compounds
01/16/2007US7163943 e.g., 6-(3-Chloro-4-methoxy-phenoxy)-N-cycloheptyl-N'-methyl-N'-(1-methyl-piperidin-4-yl)-[1,3 ,5]triazine-2,4-diamine; inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells and inhibit smooth muscle proliferation.
01/11/2007US20070010556 Thiophene derivatives as chk 1 inhibitors
01/11/2007US20070010511 Organic compounds
01/10/2007EP1741710A1 Pyrrolidine derivative
01/10/2007EP1740575A2 Pyrrolidine derivatives useful as bace inhibitors
01/10/2007EP1740573A1 Amides as bace inhibitors
01/10/2007EP1740177A2 Muscarinic acetylcholine receptor antagonists
01/09/2007US7160907 Pleuromutilin derivatives
01/09/2007US7160876 Fused bicycloheterocycle substituted quinuclidine derivatives
01/04/2007WO2004110609A3 Catalytic asymmetric desymmetrization of prochiral and meso cyclic anhydrides
01/04/2007US20070004729 Methods and compositions of novel triazine compounds
01/03/2007EP1737863A2 2-cyanopyrrolidinecarboxamides as dipeptidyl peptidase-iv inhibitors
01/03/2007EP1737854A1 NOVEL 2-(1-AZA-BICYCLO[2.2.2]OCT-3-yl)-2,3-DIHYDROISOINDOL-l-ONE/5,6-DIHYDRO-FURO[2,3-c]PYRROL-4ONE DERIVATIVES LIGANDS FOR ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR
01/03/2007EP1737852A2 Polycyclic pyridines as potassium ion channel modulators
01/03/2007EP1737842A1 Selected cgrp antagonists, method for producing the same and the use thereof as drugs
01/03/2007CN1293063C Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
12/2006
12/28/2006US20060293536 via non-racemic cinchona-alkaloid-type catalyst (quinidine) for addition of nucleophile
12/28/2006US20060293521 Including polyether substituents including pendant alkoxy fluoroalkyl groups; for wetting, leveling and flow agents in solvent-borne coating systems
12/27/2006EP1735306A2 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
12/27/2006EP1735305A2 3-quinuclidinyl heteroatom bridged biaryl derivatives
12/27/2006EP1735286A1 Tetrahydro-indazole cannabinoid modulators
12/27/2006EP1436267B1 Lactam derivatives as antagonists for human 11cby receptors
12/27/2006EP1404704B1 Bridged bicyclic serine protease inhibitors
12/27/2006CN1886362A Preparation and use of alkylating agents
12/26/2006US7153959 treatment of tumor necrosis factor mediated disorders; asthma; inflammatory bowel disease; arthritis
12/26/2006US7153882 (Aminocarbonyloxy)-benzofused ring derivatives; Alzheimer*s disease; neurodegenerative disorders
12/21/2006WO2006134318A1 Pyrazole-substituted benzimidazole derivatives for use in the treatment of cancer and autoimmune disorders
12/21/2006WO2005072376A3 Anionic-sweetener-based ionic liquids and methods of use thereof
12/21/2006WO2005047244A3 Inhibition of fgfr3 and treatment of multiple myeloma
12/21/2006US20060287539 Chemical intermediates for production of sibutramine
12/20/2006EP1732920A2 Thiophene derivatives as chk 1 inhibitors
12/20/2006EP1732547A2 Anti-hiv quinuclidine compounds
12/20/2006CN1882584A 4-substituted imidazoles
12/20/2006CN1882583A 5-substituted imidazoles
12/19/2006CA2372238C Polymorphs of a crystalline azabicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions
12/14/2006WO2006132197A1 HETEROCYCLIC COMPOUND HAVING TYPE I 11β HYDROXYSTEROID DEHYDROGENASE INHIBITORY ACTIVITY
12/14/2006US20060281733 4-Bromo-5-(2-chloro-benzoylamino)-1H-pyrazole-3-carboxylic acid (2-pyrrolidin-1-yl-ethyl)-amide; 5-(2-chlorobenzoylamino)-1H-pyrazole-3-carboxylic acid {2-[4-(4,5-dihydro-1H-imidazol-2-yl)-phenyl]ethyl}amide; useful for the moderation of pain, septic shock, and scarring
12/14/2006US20060281666 Substitute thiophenes and uses therof
12/13/2006EP1730112A1 3-((hetero)arylsulfonyl)-8'[ (aminoalkyl)oxy]quinolines as 5-ht6 receptor antagonists for the treatment of cns disorders
12/13/2006CN1878766A Methods for synthesizing quinolinone compounds
12/12/2006US7148219 Biaryl heterocyclic compounds and methods of making and using the same
12/07/2006WO2006130453A1 Asymmetric aldol additions using bifunctional cinchona-alkaloid-based catalysts
12/07/2006WO2006130437A2 Asymmetric carbon-carbon-bond-forming reactions catalyzed by bifunctional cinchona alkaloids
12/06/2006EP1728791A1 Composition for solid pharmaceutical preparation of solifenacin or salt thereof
12/06/2006EP1727817A1 Azabicyclooctan-3-one derivatives and use thereof
12/06/2006EP1270577B1 Furoisoquinoline derivatives, process for producing the same and use thereof
11/2006
11/30/2006WO2006111662A3 4h-1,2,4-triazin-5-one derivatives, their preparation and their use as alpha 7 nicotinic acetylcholine receptors
11/30/2006US20060270729 Agents useful for reducing amylioid precursor protein and treating dementia and methods of use thereof
11/30/2006US20060270660 Processes for preparing substituted pyrimidines
11/30/2006US20060270613 2,3,4,5,6-Pentahydroxyhexylamide of 4-(4-{4-[3-[3-(4-fluorophenyl)-3-hydroxypropyl]-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]benzylcarbamoyl}phenoxy)benzoic acid, for example; antilipemic agents; anticholesterol agents
11/29/2006EP1726304A1 Solifenacin-containing composition
11/29/2006EP1725552A1 New quaternized quinuclidine esters
11/29/2006EP1725538A1 Pyridazinone ureas as antagonists of a4 integrins
11/29/2006EP1725236A1 Novel m3 muscarinic acetylcholine receptor antagonists
11/29/2006EP0738149B1 1-aminoindan derivatives and compositions thereof
11/29/2006CN1871241A Spirofuropyridine aryl derivatives
11/29/2006CN1871235A Azabicyclic-substituted fused heteroaryl compounds for the treatment of disease
11/28/2006US7141671 Biphenyl derivatives
11/23/2006US20060264441 N-[(1-azabicyclo[2.2.2]oct-2-yl)arylmethyl]-benzamide derivatives; psychological, behavioral, eating, sexual, sleep, nervous system, and/or neurodegenerative disorders; drug abuse, alcoholism, schizophrenia, psychoses, Parkinson*s disease, epilepsy; analgesics, antidepressants, anxiolytic agents
11/23/2006US20060264426 Antiinfective agent, antiproliferation agent, antiinflammatory agent or prokinetics
11/23/2006US20060264419 Substituted pyrazoles
11/21/2006US7138410 Aza-bicyclic N-biarylamides with affinity for the α7 nicotinic acetylcholine receptor
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