| Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704) |
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| 03/05/2015 | US20150065537 Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists |
| 03/03/2015 | US8969584 PIM kinase inhibitors and preparation methods and use in medicinal manufacture thereof |
| 03/03/2015 | US8969571 Biphenyl derivatives |
| 02/26/2015 | US20150057272 Benzimidazoles and related analogs as sirtuin modulators |
| 02/26/2015 | US20150056699 Small molecule inducers of gdnf as potential new therapeutics for neuropsychiatric disorders |
| 02/24/2015 | CA2620379C Synthetic methods and intermediates for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders |
| 02/17/2015 | US8957081 Compounds and compositions as protein kinase inhibitors |
| 02/17/2015 | US8957078 Compounds useful as inhibitors of ATR kinase |
| 02/17/2015 | CA2675118C Novel quinuclidine derivative useful in the preparation of mequitazine |
| 02/12/2015 | WO2015019325A1 Benzimidazolyl-methyl urea derivatives as alx receptor agonists |
| 02/12/2015 | US20150045386 (2s,3r)-n-2-3-pyridinylmethyl-1-azabicyclo 2.2.2 oct-3-yl benzofuran-2-carboxamide, novel salt forms, and methods of use thereof |
| 02/10/2015 | US8952165 Pharmaceutical composition comprising pyridone derivatives |
| 02/10/2015 | CA2538520C Preparation and use of alkylating agents |
| 02/04/2015 | EP2831070A1 Process of preparing solifenacin or salt thereof, and novel intermediate used in the process |
| 02/03/2015 | US8946429 Kinetic resolution |
| 01/29/2015 | US20150031891 Bis-quarternary cinchona alkaloid salts as asymmetric phase transfer catalysts |
| 01/29/2015 | US20150031675 Diazabicyclo[3.3.1]nonanes, methods of synthesis, and uses thereof |
| 01/29/2015 | US20150031667 Substituted Pyrazolo [1,5-A] Pyrimidine Compounds as TRK Kinase Inhibitors |
| 01/28/2015 | CN104311551A 一种帕洛诺司琼司琼化合物的制备工艺 One kind of palonosetron granisetron Joan Preparation of compounds |
| 01/27/2015 | US8940763 Combinations of solifenacin and salivary stimulants for the treatment of overactive bladder |
| 01/22/2015 | WO2015007073A1 Quinine compounds, and optical isomers, preparation method and medical use thereof |
| 01/21/2015 | EP2825536A1 Bis-quarternary cinchona alkaloid salts as asymmetric phase transfer catalysts |
| 01/20/2015 | US8937150 Anti-viral compounds |
| 01/20/2015 | US8937061 Stereoselective total synthesis of noribogaine |
| 01/08/2015 | US20150011534 Pyridazinone derivatives |
| 01/07/2015 | CN102207494B 同时测定盐酸帕洛诺司琼四种光学异构体的方法 Simultaneous determination of palonosetron hydrochloride four optical isomers |
| 01/06/2015 | US8927722 Processes and intermediates for preparing a macrocyclic protease inhibitor of HCV |
| 01/06/2015 | US8927540 Pyridazinone derivatives |
| 01/06/2015 | US8927503 Modulations of protease activated receptors |
| 01/01/2015 | US20150005322 Pyrido[3,4-b] indoles and methods of use |
| 12/30/2014 | US8921544 Oxazole tyrosine kinase inhibitors |
| 12/30/2014 | US8921514 Anti-viral compounds |
| 12/30/2014 | US8921399 Therapeutic isoxazole compounds |
| 12/30/2014 | US8921357 Pyridazinone derivatives |
| 12/23/2014 | US8916130 Synthesis of MSE-framework type molecular sieves |
| 12/18/2014 | US20140371460 Glucosylceramide synthase inhibitors |
| 12/18/2014 | US20140371264 Muscarinic acetylcholine receptor antagonists |
| 12/18/2014 | US20140371213 3,4-disubstituted 1h-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators |
| 12/11/2014 | US20140364451 Tropinol esters and related compounds to promote normal processing of app |
| 12/10/2014 | CN104193741A 作为α7-烟碱乙酰胆碱受体配体的奎宁环-4-基甲基1H-吲哚-3-甲酸酯衍生物 As α7- nicotinic acetylcholine receptor ligands quinuclidine-4-methyl-1H- indole-3-carboxylic acid ester derivatives |
| 12/10/2014 | CN104193740A 作为沉默调节蛋白调节剂的苯并咪唑类和相关的类似物 As a sirtuin modulators benzimidazole class and related analogs |
| 12/04/2014 | US20140357741 Methods and compositions for preparing and purifying noribogaine |
| 11/27/2014 | US20140350261 Method for catalytic asymmetric synthesis of optically active isoxazoline compound, and optically active isoxazoline compound |
| 11/27/2014 | US20140350008 2-heteroaryl carboxamides |
| 11/25/2014 | US8895741 Process for the synthesis of biaryl oxazolidinones |
| 11/13/2014 | US20140336378 Novel benzamide derivative and use thereof |
| 11/11/2014 | US8884017 2-heteroarylcarboxylic acid amides |
| 11/04/2014 | US8877921 Synthetic voacangine |
| 11/04/2014 | US8877759 Aminopyrazines as ATR kinase inhibitors |
| 10/30/2014 | US20140323458 Substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes useful for treating hcv infections |
| 10/23/2014 | US20140315891 N-substituted noribogaine prodrugs |
| 10/14/2014 | US8859764 Methods and compositions for preparing noribogaine from voacangine |
| 10/09/2014 | US20140303374 Method for producing compound with carbonyl group by using ruthenium carbonyl complex having tridentate ligand as dehydrogenation oxidation catalyst |
| 10/09/2014 | US20140303182 Pharmaceutically acceptable salts of quinolinone compounds having improved pharmaceutical properties |
| 10/09/2014 | US20140303126 Novel quinuclidine derivatives and medicinal compositions containing the same |
| 10/08/2014 | EP2786986A2 Novel benzamide derivative and use thereof |
| 10/07/2014 | US8853404 Muscarinic acetylcholine receptor antagonists |
| 10/02/2014 | US20140296527 Processes for the preparation of pyrrolidine intermediates |
| 09/30/2014 | US8846715 (2S,3R)-N-(2((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide novel salt forms, and methods of use thereof |
| 09/30/2014 | US8846655 4-substituted-2-phenoxy-phenylamine delta opioid receptor modulators |
| 09/25/2014 | WO2014152215A1 SALT FORMS OF (S)-Quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl)carbamate |
| 09/25/2014 | WO2014151291A1 Method of preparing glucosylceramide synthase inhibitors |
| 09/25/2014 | US20140288118 N-biarylamides |
| 09/25/2014 | US20140288114 Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders |
| 09/23/2014 | US8841309 Substituted pyrazines and their use in the treatment of disease |
| 09/23/2014 | US8841290 Substituted tetrahydronaphthalenes, method for the production thereof, and use thereof as drugs |
| 09/23/2014 | CA2551686C Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| 09/18/2014 | WO2014140318A1 Improved process for acyl transfer reactions |
| 09/18/2014 | WO2014140091A1 Substituted 2-aza-bicyclo[2.2.2]octane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin c |
| 09/18/2014 | US20140275011 Pyridine cdk9 kinase inhibitors |
| 09/18/2014 | US20140275009 Compounds useful as inhibitors of atr kinase |
| 09/17/2014 | EP2778167A1 Stable pharmaceutical composition comprising amorphous solifenacin or its pharmaceutically acceptable salt |
| 09/16/2014 | US8835682 Alkaloid aminoester derivatives and medicinal composition thereof |
| 09/11/2014 | US20140256730 Treprostinil derivative compounds and methods of using same |
| 09/11/2014 | US20140255381 Glucosylceramide synthase inhibitors |
| 09/04/2014 | US20140249313 Conjugate Addition Reactions Using Bifunctional Cinchona-Alkaloid-Based Catalysts |
| 09/04/2014 | US20140249179 Crystalline Form of (R)-7-Chloro-N-(Quinuclidin-3-YL)benzo[B]thiophene-2-Carboxamide Hydrochloride Monohydrate |
| 09/03/2014 | EP2772490A1 Aminoalkyl-substituted n-thienyl benzamide derivative |
| 08/21/2014 | US20140235864 Biphenyl derivatives |
| 08/21/2014 | US20140234443 5-ht3 receptor modulators, methods of making, and use thereof |
| 08/19/2014 | US8809381 Highly selective sigma receptor ligands |
| 08/14/2014 | US20140228575 Process for the Preparation of Solifenacin and Salts Thereof |
| 08/14/2014 | US20140228574 Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV |
| 08/14/2014 | US20140228350 Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders |
| 08/13/2014 | CN103980270A 一种（r）-3-奎宁醇的制备方法 One kind of (r) -3- quinine preparation of alcohol |
| 08/12/2014 | US8802832 Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
| 08/12/2014 | US8802699 Quinuclidine derivatives and medicinal compositions containing the same |
| 08/12/2014 | CA2520225C Benzenesulfonamide derivatives |
| 08/07/2014 | US20140220125 Salts of aza-bicyclic di-aryl ethers and methods to make them or their precursors |
| 08/06/2014 | EP2762475A1 Pharmaceutically acceptable salts of quinolinone compounds and their medical use |
| 07/30/2014 | EP2758395A1 Compounds useful as inhibitors of choline kinase |
| 07/30/2014 | EP2758386A1 Processes and intermediates for preparing a macrocyclic protease inhibitor of hcv |
| 07/30/2014 | CN103958477A 新苯甲酰胺衍生物及其用途 The new benzamide derivatives and their use |
| 07/30/2014 | CN102584816B 一种多环式叔胺的制备方法 Method for preparing polycyclic tertiary amines |
| 07/29/2014 | US8791262 Asymmetric friedel-crafts alkylations catalyzed by bifunctional cinchona alkaloids |
| 07/24/2014 | US20140206660 Phenyl-Heteroaryl Derivatives and Methods of Use Thereof |
| 07/17/2014 | WO2014110491A1 Prodrugs of treprostinil |
| 07/16/2014 | EP2754660A1 Pyridazinon derivatives |
| 07/15/2014 | US8779147 3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators |
| 07/15/2014 | US8779127 Processes for preparing substituted pyrimidines |