Patents
Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704)
12/2011
12/01/2011US20110295011 Conjugate Addition Reactions Using Bifunctional Cinchona-Alkaloid-Based Catalysts
12/01/2011US20110294780 SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-a MODULATORS
12/01/2011US20110294749 Diaminopyrimidinecarboxamide derivative
11/2011
11/30/2011EP2389378A1 Preparation and therapeutic applications of (2s,3r)-n-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
11/30/2011CN102264734A 生物碱氨基酯衍生物及其药用组合物 Alkaloid aminoester derivatives and pharmaceutical compositions
11/30/2011CN102264727A 哒嗪酮衍生物 Pyridazinone derivatives
11/30/2011CN102264715A 用于制备hcv的大环蛋白酶抑制剂的方法及中间体 Methods for the preparation of macrocyclic protease inhibitors and intermediates hcv
11/30/2011CN101056634B 奎宁环衍生物及它们作为毒蕈碱m3受体拮抗剂的用途 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists
11/24/2011WO2011146511A1 A crystalline form of (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate
11/24/2011CA2799744A1 A crystalline form of (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate
11/22/2011CA2484395C Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for the preparation thereof
11/16/2011EP2094693B1 A method for the preparation of solifenacin
11/16/2011CN101411996B Macromolecule supported Cinchona bases compound, production method and application
11/15/2011US8058464 Isotopically labeled chemically stable reagents and process for the synthesis thereof
11/02/2011EP2382198A1 Processes and intermediates for preparing a macrocyclic protease inhibitor of hcv
11/01/2011US8048893 Pyrazolyl derivatives, preparation process and intermediates of this process as medicinal products and pharmaceutical compositions containing them
11/01/2011CA2523436C Quinuclidine derivatives binding to mucarinic m3 receptors
10/2011
10/27/2011WO2011132444A1 Modified carbonyl reductase, gene thereof, and method of producing optically active alcohols using these
10/27/2011US20110263859 (2s, 3r)-n-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide, novel salt forms, and methods of use thereof
10/27/2011US20110263591 2-heteroaryl carboxamides
10/26/2011EP2176250B1 Substituted heteroarylpiperidine derivatives as melanocortin-4 receptor modulators
10/26/2011EP1518855B1 Diaminopyrimidinecarboxa mide derivative
10/26/2011CN102227420A Quinazolinone, quinolone and related analogs as sirtuin modulators
10/26/2011CN102225926A Pharmaceutically acceptable salts of quinolinone compounds having improved pharmaceutical properties
10/25/2011US8044205 Process for manufacturing 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide
10/25/2011US8044068 Aminopyrrolidine compound
10/20/2011US20110257403 Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV
10/20/2011US20110257224 Preparation and therapeutic applications of (2s,3r)-n-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
10/19/2011EP2376489A1 Alkaloid aminoester derivatives and medicinal composition thereof
10/19/2011EP1482931B1 Mono- and bicyclic azole derivatives that inhibit the interaction of ligands with rage
10/18/2011US8039483 Quinuclidine carbonate salts and medicinal composition thereof
10/18/2011US8039482 Composition of solifenacin or salt thereof for use in solid formulation
10/12/2011CN102212064A Method for preparing quinindium and cinchonine
10/11/2011US8034942 Process for the preparation of solifenacin
10/06/2011US20110245486 Method for the production of 1,4-benzothiepin-1,1-dioxide derivatives
10/06/2011US20110245292 2-hydroxy-ethanesulfonate salt
10/05/2011EP1278758B1 Combretastatin A-1 phosphate and Combretastatin B-1 phosphate prodrugs
10/05/2011CN102209717A Compounds for the treatment of hepatitis c
10/05/2011CN102207494A Method for simultaneously determining four optical isomers of palonosetron hydrochloride
10/04/2011US8030329 N-biarylamides
09/2011
09/28/2011EP2367815A1 Pyridazinone derivatives
09/27/2011US8026239 Cell differentiation inducer
09/14/2011EP2364312A2 Preparation of crystalline palonosetron hydrochloride
09/14/2011CN102186826A Diazonium-free method to make an indazole intermediate in the synthesis of bicyclic 5-(trifluormethoxy)-1h-3-indazolecarboxylic acid amides
09/07/2011CN102174017A Pyrazolyl derivatives in the form of drugs for treating acute or chronic neuronal regressions
09/06/2011US8012959 Diaminopyrimidinecarboxamide derivative
09/01/2011WO2011104089A1 Process for the preparation of isoxazoline derivatives
09/01/2011US20110213151 Cinchona-based bifunctional organocatalysts and method for preparing chiral hemiesters using the same
09/01/2011US20110213150 Preparation of crystalline palonosetron hydrochloride
09/01/2011US20110212957 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof
09/01/2011CA2790963A1 Process for the preparation of isoxazoline derivatives
08/2011
08/31/2011CN102167698A Difunctional thioamide organic micromolecule catalyst, preparation method thereof and application thereof
08/30/2011US8008289 α-aminocyclolactam ligands for G-protein coupled receptors
08/30/2011US8008288 Anti-inflammatory A-aminocyclolactam compounds
08/25/2011WO2011101069A2 Hetarylaminonaphthyridines
08/25/2011US20110207769 Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabicyclo [2.2.2]oct-3-yl ester
08/25/2011CA2790613A1 Hetarylaminonaphthyridines
08/18/2011US20110200587 Aminothiazolones as estrogen related receptor-alpha modulators
08/17/2011EP2357173A1 New alkyne compounds with MCH-antagonistic activity and medicaments containing them
08/17/2011CN1878766B Methods for synthesizing quinolinone compounds
08/17/2011CN102151273A 2,4,6-triamino-1,3,5-triazine derivative
08/11/2011US20110193019 Alkaloid monomers, liquid crystal compositions and polymer networks derived therefrom
08/10/2011CN1129942B Aza spiro-compounds acting on the cholinergic system with muscarinic agonist activity
08/10/2011CN102146053A 2-phenoxy- and 2-phenylsulfonamide derivatives with CCR3 antagonistic activity for the treatment of inflammatory or immunological disorders
08/09/2011CA2552050C Substituted heterocycles and the uses thereof
08/09/2011CA2512000C Selective estrogen receptor modulator
08/04/2011WO2011001400A9 Processes for the preparation of form i and form ii of palonosetron hydrochloride
08/03/2011EP2349263A2 Modulators of cystic fibrosis transmembrane conductance regulator
08/03/2011CN101613349B Preparation method of S-3-aminoquinuclidine dihydrochloride
08/02/2011US7989660 Bactericide against gramnegative bacteria; respiaratory system disorders
08/02/2011CA2564757C Method for producing solifenacin or salts thereof
08/02/2011CA2479109C Radiolabelled quinoline and quinolinone derivatives and their use as metabotropic glutamate receptor ligands
08/02/2011CA2470956C 1-alkyl-1-azoniabicyclo[2.2.2]octane carbamate derivatives and their use as muscarinic receptor antagonists
07/2011
07/27/2011EP2346833A1 Diazonium-free method to make an indazole intermediate in the synthesis of bicyclic 5-(trifluormethoxy)-1h-3-indazolecarboxylic acid amides
07/27/2011CN102137848A 2,4-diaminopyrimidine compound
07/21/2011WO2011086003A1 Process for the preparation of solifenacin and solifenacin succinate
07/20/2011EP2344475A1 Quinazolinone, quinolone and related analogs as sirtuin modulators
07/20/2011CN1930137B Novel benzothiazepine and benzothiepine compounds
07/20/2011CN101239971B Biphenyl derivatives
07/20/2011CN101239970B Biphenyl derivatives
07/20/2011CN101239969B Biphenyl derivatives
07/20/2011CN101239968B Biphenyl derivatives
07/19/2011US7981906 (2S,3R)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl-benzofuran-2-carboxamide, novel salt forms, and methods of use thereof
07/14/2011US20110172428 Methods for the preparation of indazole-3-carboxylic acid and n-(s)-1-azabicyclo[2.2.2]oct-3-yl-1h-indazole-3-carboxamide hydrochloride salt
07/14/2011US20110172237 Quinuclidine derivatives as muscarinic m3 receptor antagonists
07/14/2011US20110172174 Antibacterial agents
07/13/2011CN102120740A Imidazoline compound chirally synthesized by using thiourea catalyst derived from rosin and application thereof in anti-inflammatory and antipyretic aspects
07/12/2011US7977485 2-heteroaryl carboxamides
07/06/2011CN1777577B Antibacterial agents
07/06/2011CN102115446A Method for catalytically synthesizing chiral curcumin analogs
07/05/2011US7973030 Benzothiazepine and benzothiepine compounds
07/05/2011CA2483228C Carboxamides
06/2011
06/29/2011CN102112474A Quinuclidine carbonate derivatives and medicinal composition thereof
06/29/2011CN101490048B Process for manufacturing 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3- phenoxypropyl)-1 -azoniabicyclo[2.2.2]octane bromide
06/28/2011CA2445834C Dihydroimidazo[4,5-e]indole and 7h-pyrrolo[3,2-f]quinoxaline derivatives as nicotinic acetylcholine receptor ligands and/or serotonergic ligands
06/23/2011CA2781390A1 Bridged bicyclic rho kinase inhibitor compounds, composition and use
06/22/2011EP2336128A1 Benzoisothiazoles and preparation and uses thereof
06/16/2011WO2011070028A1 Kinetic resolution
06/15/2011EP2332895A1 Kinetic Resolution
06/15/2011CN1956964B Tetrahydro-indazole cannabinoid modulators
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 ... 58