| Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704) |
|---|
| 01/12/2011 | CN101157691B Production technique of hydrochloric acid palonosetron |
| 01/06/2011 | WO2011001400A2 Processes for the preparation of form i and form ii of palonosetron hydrochloride |
| 01/06/2011 | US20110003849 Soluble epoxide hydrolase inhibitors, compositions containing such compounds and methods of treatment |
| 01/06/2011 | US20110003802 Bridged N-Cyclic Sulfonamido Inhibitors of Gamma Secretase |
| 01/06/2011 | US20110003799 3,4-disubstituted 1h-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators |
| 01/05/2011 | EP2270114A1 Photobase generator |
| 01/05/2011 | CN101939311A Heterocyclic compounds with affinity to muscarinic receptors |
| 01/04/2011 | US7863271 2-aminobenzoxazole carboxamides as 5HT3 modulators |
| 12/29/2010 | EP1776360B1 3-(heteroaryl-oxy)-2-alkyl-1-aza-bicycloalkyl derivatives as alpha.7-nachr ligands for the treatment of cns diseases. |
| 12/29/2010 | EP1001946B1 QUINOXALINE COMPOUNDS WHICH INHIBIT PLATELET-DERIVED GROWTH FACTOR AND/OR p56lck TYROSINE KINASES |
| 12/23/2010 | US20100324085 Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists |
| 12/23/2010 | US20100324025 Antibacterial Agents |
| 12/22/2010 | CN101925600A Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabicyclo [2.2.2]oct-yl ester |
| 12/16/2010 | WO2010144043A1 A novel 4-methylbenzenesulphonate salt and a process for preparing a pharmaceutical composition comprising the salt |
| 12/16/2010 | US20100317842 Development of Molecular Imaging Probes for Carbonic Anhydrase-IX Using Click Chemistry |
| 12/15/2010 | CN101913973A Preparation and use of alkylating agents |
| 12/08/2010 | EP2258682A2 Amino-substituted tricyclic derivatives and methods of use |
| 12/08/2010 | EP1781290B1 Anti-inflammatory agents |
| 12/08/2010 | CN101910170A (1,4-diaza-bicyclo[3.2.2]non-6-en-4-yl)-heterocyclyl-methanone ligands for nicotinic acetylcholine receptors, useful for the treatment of disease |
| 12/01/2010 | EP2256117A1 Quiniclidine derivatives of (hetero) arylcycloheptanecarboxylic acid as muscarinic receptor antagonists |
| 12/01/2010 | EP2256106A1 3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinases (CDK) and glycogen synthase kinase-3 (GSK-3) modulators |
| 11/30/2010 | US7842687 Cephalotaxane derivatives and their processes of preparation and purification |
| 11/25/2010 | US20100298371 Process for preparing chemically and chirally pure solifenacin base and its salts |
| 11/24/2010 | EP2253631A1 Spyrocyclic quiniclidinic ether derivatives |
| 11/24/2010 | EP1497287B1 Quinoline derivatives in combination with 5-FU or CPT-11 for use in the treatment of cancer |
| 11/23/2010 | US7838527 Methods of treating cancer and related methods |
| 11/23/2010 | CA2423192C 1-azabicyclo[2.2.2]octan-3-one derivatives and maleimide derivatives and their use for treating cancer tumors |
| 11/18/2010 | WO2010131145A1 Cyclobutenedione derivatives |
| 11/18/2010 | US20100292267 Palonosetron free base and process for its preparation |
| 11/11/2010 | US20100286195 Novel benzooxazol-and benzooxathiol-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 11/10/2010 | CN1980889B Adamantyl pyrrolidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| 11/10/2010 | CN101883771A Quinuclidin-4-ylmethyl 1H-indole-3-carboxylate derivatives as alpha 7 nicotinic acetylcholine receptor ligands for the treatment of alzheimer's disease |
| 11/09/2010 | US7829715 reacting succinic acid with solifenacin to form solifenacin succinate; treating urinary incontinence, overactive bladder, urogenital disorders |
| 11/09/2010 | US7829583 Biphenyl derivatives |
| 11/09/2010 | CA2496164C Benzimidazole quinolinones and uses thereof |
| 11/03/2010 | EP2246345A1 Biphenyl derivatives having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity |
| 11/02/2010 | US7825140 3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators |
| 10/28/2010 | WO2010121963A1 Resorcinol derivatives as hsp90 inhibitors |
| 10/28/2010 | WO2009139002A3 An improved process for the preparation of solifenacin and its pharmaceutically acceptable salts thereof |
| 10/27/2010 | CN101869846A Catalyst of first category bi-quinine or bi-quinidine, synthesis method and application |
| 10/26/2010 | CA2457053C Preventive agent/remedial agent for constipation predominant ibs |
| 10/26/2010 | CA2192928C Benzoheterocyclic derivatives |
| 10/13/2010 | CN1886362B Preparation and use of alkylating agents |
| 10/13/2010 | CN101857593A 9-amino quinine derivative and 9-amino-cinchonidine derivative and synthetic method thereof |
| 10/13/2010 | CN101255157B Crystal system of chlorhydric acid palonosetron and preparation method thereof |
| 10/07/2010 | WO2010113834A1 Pyrimidine compound |
| 10/07/2010 | US20100256201 Cell differentiation inducer |
| 10/07/2010 | US20100256119 Azole derivatives and fused bicyclic azole derivatives as therapeutic agents |
| 10/07/2010 | CA2757188A1 Pyrimidine compound |
| 10/06/2010 | EP1633752B1 Isoquinoline-3-carboxylic acid amides and pharmaceutical uses thereof |
| 10/06/2010 | CN101851233A Palonosetron hydrochloride, and precursor compound and preparation method thereof |
| 10/06/2010 | CN101402634B Separation and purification process for alkaloid in cinchona bark |
| 09/30/2010 | US20100249420 Process for preparing quinuclidinium carbamate derivatives |
| 09/29/2010 | EP2231658A2 Palonosetron free base and process for its preparation |
| 09/29/2010 | EP1727817B1 Azabicyclooctan-3-one derivatives and use thereof |
| 09/29/2010 | EP1615889B1 Biphenyl derivatives having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity |
| 09/28/2010 | US7803792 benzothiazepine compounds having a thioamide bond and a quaternary ammonium substituent, exhibiti a potent ileal bile acid transporter inhibiting activity, used for for treating hyperlipidemia or arteriosclerosis |
| 09/23/2010 | US20100240696 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| 09/22/2010 | EP2229387A1 Process for preparing chemically and chirally pure solifenacin base and its salts |
| 09/22/2010 | EP2229374A1 Amido-thiophene compounds and their use as 11-beta-hsd1 inhibitors |
| 09/16/2010 | WO2010103529A1 A new method for the preparation of solifenacin and new intermediate thereof |
| 09/16/2010 | US20100234591 Biaryl heterocyclic compounds and methods of making and using the same |
| 09/16/2010 | US20100234354 Pyridazinone derivatives |
| 09/16/2010 | US20100234333 Novel quinuclidine derivatives and medicinal compositions containing the same |
| 09/16/2010 | US20100234332 Novel quinuclidine derivatives and medicinal compositions containing the same |
| 09/15/2010 | EP1811999B1 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists |
| 09/15/2010 | CN101830896A Organic acid salt of optical isomer of penehyclidine |
| 09/14/2010 | US7795453 6-[(Anilinocarbonyl)amino]-N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzothiophene-2-carboxamide hydrochloride; treatment of dementia, attention deficit hyperactivity disorder and impairments of learning and memory |
| 09/14/2010 | US7795272 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof |
| 09/08/2010 | CN1732154B Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds |
| 09/08/2010 | CN101824033A Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| 09/07/2010 | US7790719 used for the treatment of cachexia and other weight loss disorders, such as those resulting from cancer, HIV, old age and anorexia nervosa |
| 09/07/2010 | CA2492081C Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders |
| 09/02/2010 | US20100222378 2-heteroarylcarboxylic acid amides |
| 09/02/2010 | US20100222361 2-acylaminothiazole derivative or salt thereof |
| 09/02/2010 | US20100222329 2-acylaminothiazole derivative or salt thereof |
| 08/31/2010 | US7786162 Agents useful for reducing amyloid precursor protein and treating dementia and methods of use thereof |
| 08/26/2010 | WO2010094210A1 Preparation method of (4s,5r)-half-ester |
| 08/25/2010 | EP2220082A2 Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester |
| 08/25/2010 | EP1517892B1 Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof |
| 08/25/2010 | CN101054375B Compound capable of inhibiting tubercle bacillus growth and application thereof |
| 08/24/2010 | US7781430 Benzoxazole carboxamides for treating CINV and IBS-D |
| 08/19/2010 | WO2010092153A1 New substituted tetrahydronapthalenes, method for the production thereof, and use thereof as drugs |
| 08/19/2010 | WO2010056656A3 Preparation of crystalline palonosetron hydrochloride |
| 08/19/2010 | WO2009122034A8 Novel hsp90 inhibitory carbazole derivatives, compositions containing same, and use thereof |
| 08/18/2010 | EP2217597A1 Quinuclidin-4-ylmethyl 1h-indole-3-carboxylate derivatives as alpha 7 nicotinic acetylcholine receptor ligands for the treatment of alzheimer's disease |
| 08/18/2010 | EP1874761B1 4h-1,2,4-triazin-5-one derivatives, their preparation and their use as alpha 7 nicotinic acetylcholine receptors |
| 08/18/2010 | EP1737842B1 Selected cgrp antagonists, method for producing the same and the use thereof as drugs |
| 08/17/2010 | US7776879 anticholinergic agents such as Butylthiophen-2-ylmethylcarbamic acid 1-azabicyclo[2.2.2]oct-3-(R)yl ester, having a high affinity for muscarinic M3 receptors, useful for treating respiratory system, urogenital, gastrointestinal and cardiovascular disorders |
| 08/17/2010 | US7776309 Such as fluoromethyl-tyrosine and/or N,N-methyl-N-fluoromethylethanolamine |
| 08/12/2010 | WO2010091164A1 Inhibitors of glucosylceramide synthase |
| 08/11/2010 | EP1537099B1 Pyrrole based inhibitors of glycogen synthase kinase 3 |
| 08/11/2010 | CN101801950A Substituted heteroarylpiperidine derivatives as melanocortin-4 receptor modulators |
| 08/11/2010 | CN101797519A Application of fluoro-diphenyl sulfimide as nitrogen heterocyclic Diels-Alder reaction catalyst |
| 08/05/2010 | WO2010012459A3 A process for the preparation of solifenacin salts and their inclusion into pharmaceutical dosage forms |
| 08/05/2010 | US20100197662 Heterocyclic compound having type i 11 beta hydroxysteroid dehydrogenase inhibitory activity |
| 08/05/2010 | US20100196368 Substituted benz-azoles and methods of their use as inhibitors of raf kinase |
| 08/04/2010 | CN101796050A Process for production of optically active 3-quinuclidinol derivative |
| 08/04/2010 | CN101792441A Crystal forms of palonosetron hydrochloride and preparation method thereof |
| 08/03/2010 | US7767811 Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids |