Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704)
11/2012
11/01/2012US20120277437 Kinetic resolution
11/01/2012US20120277434 Methods for synthesizing quinolinone compounds
11/01/2012US20120276018 Alkaloid ester and carbamate derivatives and medicinal compositions thereof
11/01/2012CA2834467A1 Alkaloid ester and carbamate derivatives and medicinal compositions thereof
10/2012
10/30/2012US8299108 Substituted benzazoles and methods of their use as inhibitors of raf kinase
10/26/2012WO2012144650A1 Method for producing compound with carbonyl group by using ruthenium carbonyl complex having tridentate ligand as dehydrogenation oxidation catalyst
10/26/2012WO2012143526A1 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof
10/26/2012CA2833648A1 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof
10/26/2012CA2830471A1 Method for producing compound with carbonyl group by using ruthenium carbonyl complex having tridentate ligand as dehydrogenation oxidation catalyst
10/25/2012US20120267533 Processes for the preparation of form i and form ii of palonosetron hydrochloride
10/17/2012EP2509933A1 Kinetic resolution
10/17/2012CN102741226A 4-substituted-2-phenoxy-phenylamine delta opioid receptor modulators
10/17/2012CN102329314B Industrial preparation method of palonosetron hydrochloride
10/11/2012US20120259120 Diazonium-free method to make an indazole intermediate in the synthesis of bicyclic 5-(trifluormethoxy)-1h-3-indazolecarboxylic acid amides
10/11/2012US20120258964 2-heteroaryl carboxamides
10/10/2012CN101258151B Synthetic methods and for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders
10/09/2012US8283470 Method for the preparation of solifenacin and intermediate thereof
10/09/2012CA2476594C Mono-and bicyclic azole derivatives that inhibit the interaction of ligands with rage
10/04/2012US20120252836 1,3-Dioxanes and Their Uses
10/03/2012CN102702187A New crystal form of penehyclidine hydrochloride and preparation method of new crystal form
09/2012
09/26/2012CN102329313B Azasetron hydrochloride compound and preparation method thereof
09/20/2012US20120238549 Nuclear Hormone Receptor Modulators
09/19/2012EP2499137A1 Palonosetron metabolites
09/18/2012US8268864 Combination of anticholinergics and leukotriene receptor antagonists for the treatment of respiratory diseases
09/18/2012US8268829 Substituted pyrimidines useful as protein kinase inhibitors
09/18/2012CA2519110C Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain
09/12/2012CN101535306B Quiniclidine derivatives of (hetero) arylcycloheptanecarboxylic acid as muscarinic receptor antagonists
09/11/2012US8263619 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
09/11/2012US8263605 Modulators of muscarinic receptors
09/11/2012CA2561167C Composition of solifenacin or salt thereof for use in solid formulation
09/05/2012EP2493852A1 4-substituted-2-phenoxy-phenylamine delta opioid receptor modulators
09/04/2012US8258172 Agents useful for reducing amyloid precursor protein and treating dementia and methods of use thereof
08/2012
08/30/2012US20120220599 Aza-bicycloalkyl ethers and their use as alpha7-nachr agonists
08/29/2012EP2492264A2 Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same
08/28/2012US8252811 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof
08/28/2012CA2671744C Compounds and compositions as protein kinase inhibitors
08/23/2012US20120213791 3,4-disubstituted 1h-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators
08/22/2012EP2489666A2 Chemically and chirally pure solifenacin base and its salts
08/22/2012EP1200431B3 Quinuclidine derivatives and their use as muscarinic m3 receptors ligands
08/22/2012CN101585835B Preparation method and application of bencycloquidium bromide optical isomer and composition of bencycloquidium bromide optical isomer
08/16/2012WO2012108490A1 Isoquinoline amide derivative
08/16/2012US20120208796 Heterocyclic derivatives
08/15/2012EP1656370B1 Biaryl heterocyclic compounds and methods of making and using the same
08/14/2012US8242276 Methods for the preparation of N-(S)-1-azabicyclo[2.2.2]oct-3-yl-1H-indazole-3-carboxamide hydrochloride salt
08/14/2012US8242135 Biphenyl derivatives
08/14/2012CA2552855C Azabicyclooctan-3-one derivatives and use thereof
08/09/2012US20120202842 2-heteroarylcarboxylic acid amides
08/09/2012US20120202786 Therapeutic isoxazole compounds
08/08/2012EP2484681A1 Chemically and chirally pure gentisate salt of solifenacin
08/08/2012EP2484363A1 (2S,3R)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-5-methylthiophene-2-carboxamide
08/08/2012EP1740177B1 Muscarinic acetylcholine receptor antagonists
08/07/2012US8236803 Aza-bicycloalkyl ethers and their use as alpha7-nAChR agonists
08/02/2012WO2012102580A1 Pharmaceutical composition comprising pyridone derivatives
08/02/2012CA2824467A1 Pharmaceutical composition comprising pyridone derivatives
08/01/2012CN102617565A Asymmetrical alkylation reaction catalyzed by chiral quaternary ammonium salt
07/2012
07/31/2012CA2499128C Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof
07/24/2012US8227598 Heteroaryl carboxamides
07/24/2012US8227484 Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders
07/19/2012WO2012095418A1 Vinyl quinuclidine useful as a synthesis intermediate in the preparation of (r)-mequitazine
07/18/2012CN102584816A Method for preparing polycycle tertiary amine
07/11/2012EP2473515A1 Processes for producing optically pure -lactones from aldehydes and compositions produced thereby
07/11/2012CN102558169A Industrialized production method for efficiently extracting, separating and purifying serial cinchona alkaloid from cinchona bark
07/10/2012CA2543820C Methods for synthesizing quinolinone compounds
07/10/2012CA2527809C Isotopically labeled chemically stable reagents and process for the synthesis thereof
07/10/2012CA2407675C Combretastatin a-1 phosphate and combretastatin b-1 phosphate prodrugs
07/05/2012US20120172590 Methods for isolating alkaloids from plants
07/03/2012US8212037 Process for production of optically active quinuclidinols
06/2012
06/28/2012US20120165363 Pharmaceutical Compositions Comprising Dextromethorphan and Quinidine for the Treatment of Neurological Disorders
06/27/2012CN1826323B 3,4-disubstituted 1h-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators
06/26/2012US8207193 Quiniclidine derivatives of (hetero) arylcycloheptanecarboxylic acid as muscarinic receptor antagonists
06/26/2012US8207192 Quinuclidine compounds having quaternary ammonium group, its preparation method and use as blocking agents of acetylcholine
06/21/2012US20120157491 Muscarinic acetylcholine receptor antagonists
06/21/2012US20120157490 N-biarylamides
06/21/2012US20120157464 Use of azabicycloalkyl derivatives or pyrrolidine-2-one derivatives for the treatment or prevention of ataxia
06/20/2012EP2465850A1 Therapeutic compounds
06/20/2012EP2465501A1 (2S,3R)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide, novel salt forms, and methods of preparation
06/13/2012EP1618087B1 Antibacterial agents
05/2012
05/31/2012WO2012069275A1 Glycine derivatives and their use as muscarinic receptor antagonists
05/31/2012US20120136024 3-Substituted-2-(arlyalkyl)-1-azabicycloalkanes and Methods of Use Thereof
05/31/2012US20120134934 Glycine derivatives and medicinal compositions thereof
05/31/2012CA2820600A1 Glycine derivatives and their use as muscarinic receptor antagonists
05/30/2012EP2457911A1 3-(heteroaryl-oxy)-2-alkyl-1-aza-bicycloalkyl derivatives as alpha.7-nAChR ligands for the treatment of CNS diseases.
05/30/2012EP1757604B1 Process for producing solifenacin or its salt
05/30/2012CN1659154B Method of preparing amine stereoisomers
05/24/2012US20120129885 (2s,3r)-n-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzofurn-2-carboxamide, novel salt forms, and methods of use thereof
05/22/2012US8183257 Muscarinic acetylcholine receptor antagonists
05/18/2012WO2012062916A1 Crystalline solifenacin succinate
05/18/2012WO2012024397A3 2,5-methano-and 2,5-ethano-tetrahydrobenzazepine derivatives and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
05/18/2012CA2817336A1 Crystalline solifenacin succinate
05/17/2012US20120122826 Novel quinuclidine derivatives and medicinal compositions containing the same
05/17/2012US20120121540 Certain Nitrogen Containing Bicyclic Chemical Entities For Treating Viral Infections
05/16/2012EP2451809A1 A process for the preparation and purification of solifenacin salts
05/15/2012USRE43390 Pleuromutilin derivatives as antimicrobials
05/15/2012CA2694480C Substituted heteroarylpiperidine derivatives as melanocortin-4 receptor modulators
05/09/2012EP2448936A2 Processes for the preparation of form i and form ii of palonosetron hydrochloride
05/09/2012CN101679303B Pyridazinone derivatives
05/09/2012CN101531658B Cinchona alkaloid quaternary ammonium salt derivatives as well as preparation method and application thereof
05/08/2012US8173667 1-Aza-bicyclo[2.2.2]octane and 1-aza-bicyclo[2.2.1]heptane derivatives; psychotic, psychological, nervous system and neurodegenerative disorders; nicotinic receptor mediated diseases
05/08/2012CA2517291C Ortho-substituted aryl and heteroaryl tie-2 modulators and methods of use
05/02/2012EP1955697B1 2-aminobenzamide derivatives as vanilloid receptor 1 (vr1) inhibitors useful for the treatment of pain or bladder function disorder
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