| Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704) |
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| 06/15/2005 | EP1539754A2 Benzimidazole quinolinones and uses thereof |
| 06/15/2005 | EP1539741A1 2-thio-substituted imidazole derivatives and their use in pharmaceutics |
| 06/15/2005 | EP1539166A1 Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders |
| 06/09/2005 | WO2005051917A1 Pyrazolyl derivatives in the form of drugs for treating acute or chronic neuronal regressions |
| 06/09/2005 | WO2004012671A3 Substituted furo [2,3-b] pyridine derivatives |
| 06/09/2005 | US20050124619 Medical devices employing triazine compounds and compositions thereof |
| 06/09/2005 | US20050123475 Preparation and use of alkylating agents |
| 06/09/2005 | CA2544519A1 Pyrazolyl derivatives in the form of drugs for treating acute or chronic neuronal regressions |
| 06/08/2005 | EP1538150A1 Novel pleuromutilin derivatives |
| 06/08/2005 | EP1537104A1 Aza-bicycloalkyl ethers and their use as alpha7-nachr agonist |
| 06/08/2005 | EP1537099A1 Pyrrole based inhibitors of glycogen synthase kinase 3 |
| 06/08/2005 | CN1625410A 2, 4, 6-triamino-1, 3, 5-triazine derivative |
| 06/08/2005 | CN1205211C Pleuromutilin derivatives as antimicrobials |
| 06/07/2005 | US6903111 Isoquinuclidine derivative process for producing the same, and medicinal composition containing the same |
| 06/02/2005 | WO2005049612A1 4-substituted imidazoles |
| 06/02/2005 | WO2005049611A1 5-substituted imidazoles |
| 06/02/2005 | US20050119325 N-(1-azabicyclo[2.2.2]oct-3-yl)-heteroaryl carboxamides; alpha 7-nicotinic acetylcholine receptors (nAChR) agonists; improving perception, concentration, learning and memory; neuropathic pain; acute and chronic pain |
| 06/02/2005 | CA2546096A1 4-substituted imidazoles |
| 06/02/2005 | CA2546093A1 5-substituted imidazoles |
| 06/01/2005 | EP1351959B1 Novel pleuromutilin derivatives |
| 05/31/2005 | US6900345 Antibiotics; mutilin 14-[N-(2-carbamoyloxyethoxycarbonyl)]carbamate; therapy for bacteria infections; chemical synthesis |
| 05/26/2005 | WO2005047244A2 Inhibition of fgfr3 and treatment of multiple myeloma |
| 05/26/2005 | WO2005047230A1 Bis-cationic compounds and use thereof |
| 05/26/2005 | WO2005046590A2 Methods for synthesizing quinolinone compounds |
| 05/26/2005 | WO2005046589A2 Pharmaceutically acceptable salts of quinolinone compounds having improved pharmaceutical properties |
| 05/26/2005 | US20050113341 Stent with a disposed traiazine compound such as 6-(3-Chloro-4-methoxy-phenoxy)-N-cycloheptyl-N'-methyl-N'-(1-methyl-piperidin-4-yl)-[1,3,5]triazine-2,4-diamine for inhibiting smooth muscle proliferation; restenosis and atherosclerosis |
| 05/26/2005 | CA2544492A1 Pharmaceutically acceptable salts of quinolinone compounds having improved pharmaceutical properties |
| 05/26/2005 | CA2544186A1 Inhibition of fgfr3 and treatment of multiple myeloma with benzimidazole quinolinones |
| 05/25/2005 | EP1532144A1 Novel quinuclidine derivatives and their use |
| 05/19/2005 | US20050107460 N-heteroaryl-, naphthyl or azulenyl-substituted 1-azabicycloalkylcarboxamides; treatment and/or prophylaxis of impairments of perception, concentration, learning and/or memory |
| 05/18/2005 | CN1202093C Substituted heterocyclic compound |
| 05/18/2005 | CN1202052C Enantioselective reduction of ketones with silane agent/metal compound/chiral ligand system |
| 05/17/2005 | US6894044 Treatment of depression, anxiety, psychosis, obesity, pain, Parkinson's disease, Alzheimer's disease, neurodegenerative diseases, movement disorders, respiratory diseases, inflammatory diseases, neuropathy, immune disorders, etc. |
| 05/17/2005 | US6894042 Azabicyclic compounds for the treatment of disease |
| 05/12/2005 | WO2005042538A1 Spirofuropyridine aryl derivatives |
| 05/12/2005 | WO2005042533A2 2-cyanopyrrolidinecarboxamides as dipeptidyl peptidase-iv inhibitors |
| 05/12/2005 | WO2005042529A1 Improved aza-bridged-bicyclic amino acid derivatives as a4 integrin antagonists |
| 05/12/2005 | WO2004035575A8 Process for the preparation of (s,s)-cis-2-benzhydryl-3-benzylaminoquinuclidine |
| 05/12/2005 | CA2543533A1 2-cyanopyrrolidinecarboxamide compound |
| 05/12/2005 | CA2543438A1 Improved aza-bridged-bicyclic amino acid derivatives as a4 integrin antagonists |
| 05/12/2005 | CA2543436A1 Spirofuropyridine aryl derivatives |
| 05/10/2005 | US6890935 Pharmaceutical compositions and methods for use |
| 05/05/2005 | US20050096357 Antibiotics; therapy for infections which is caused by drug-resistant Streptococcus, or bacteria infections |
| 05/04/2005 | EP1527073A1 Benzothiophene urea, benzofurane urea, and indole urea, and use of the same as alpha-7 achr agonists |
| 05/04/2005 | CN1199971C Quaternary ammonium compounds as tachykinin antagonists |
| 05/03/2005 | US6887873 Nitrogen heteroaromatic ring connected with the same or another aromatic ring through a triazine distribution agent; anticancer agents |
| 04/28/2005 | WO2005021495A3 Quaternary salt derivatives of 1,4-diphenylazetidin-2-ones |
| 04/28/2005 | WO2005014517A3 Novel dibenzo[b,f]oxepine-10-carboxamides and pharmaceutical uses thereof |
| 04/28/2005 | US20050090540 E.g., 2,2-bis(hydroxymethyl)-1 -azabicyclo[2,2,2]octan-3-one and 2-hydroxymethyl-3,3-dihydroxy-1-azabicyclo[2,2,2]octane; these compounds reactivate the apoptosis-inducing function of mutant p53 proteins and are used to treat various types of tumors |
| 04/28/2005 | US20050090529 5-pyridin-3-yl-substituted, e.g., 5-(5-ethylaminomethyl-4-methylpyridin-3-yl)-3-(1H-imidazol-2-yl)-1H-indazole; CDK mediators, used to treat cancer, as well as proliferative diseases such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis |
| 04/28/2005 | US20050090515 anticarcinogenic, antitumor, antiproliferative agents; focal adhesion kinase (FAK) and cyclin-dependent kinase (CDK) enzyme inhibitors |
| 04/28/2005 | US20050090484 Purification of natural, synthetic or semi-synthetic crude harringtonines by reverse phase chromatography and crystallization; solvent is water or lower alkanol, or an aqueous mixture of organic solvents; enantiomerically pure; industrial scale; leukemia chemotherapy |
| 04/26/2005 | US6884893 Selective cleavage of a cycloanhydride derivative by reacting cycloanhydride with a chiral aminoalcohol in an inert solvent to form a monoester |
| 04/26/2005 | US6884807 3-bicyclic carbocyclic group substituted quinuclidine derivatives, which are cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptor and transporters |
| 04/21/2005 | WO2005035507A2 4-aminopyrimidine derivatives for treatment of hyperproliferative disorders |
| 04/21/2005 | WO2004062601A3 Antibacterial agents |
| 04/21/2005 | US20050085641 Precipitation; neutralization in presence of Lewis acid; pure enantiomorphs |
| 04/21/2005 | US20050085525 Method of treatment |
| 04/21/2005 | US20050085414 Novel medical use for tachykinin antagonists |
| 04/21/2005 | CA2542031A1 Pyrimidine derivatives for treatment of hyperproliferative disorders |
| 04/14/2005 | WO2005032548A1 Substituted benzazoles and use thereof as inhibitors of raf kinase |
| 04/14/2005 | WO2005009928A3 Preparation and use of alkylating agents |
| 04/14/2005 | WO2005007111A3 Tetrahydroquinoline derivatives as cannabinoid receptor modulators |
| 04/14/2005 | WO2004113391A3 Improved pharmaceutical drug candidates and methods for preparation thereof |
| 04/14/2005 | CA2539748A1 Substituted benzazoles and use thereof as inhibitors of raf kinase |
| 04/12/2005 | CA2194727C Process for the preparation of optically active 3-quinuclidinol |
| 04/07/2005 | WO2005012256A8 3, 4-disubstituted 1h-pyrazole compounds and their use as cyclin dependent kinases (cdk) and glycogen synthase kinase-3 (gsk-3) modulators |
| 04/07/2005 | WO2005007094A3 Asthma and allergic inflammation modulators |
| 04/07/2005 | US20050075501 Enantioselective electrophilic fluorinating agent; high yield and selectivity excess |
| 04/06/2005 | EP1519939A2 N-aryl diazaspiracyclic compounds and methods of preparation and use thereof |
| 04/06/2005 | EP1519933A1 Quinuclidine amide derivatives |
| 04/05/2005 | US6875868 Pteridine compounds for the treatment of psoriasis |
| 03/31/2005 | WO2004108086A3 HYDANTOIN DERIVATIVES AS INHIBITORS OF TUMOR NECROSIS FACTOR-α CONVERTING ENZYME (TACE) |
| 03/31/2005 | US20050070575 Such as N6-[6-(2-dimethylaminoethylamino)-4-methylsulfanyl-[1,3,5]triazin-2-yl]-2-methylquinoline-4,6-diamine, which stabilizes DNA in G-quadruplex structures (guanine tetrads); anticancer agents |
| 03/31/2005 | US20050070571 Such as N6-[6-(2-dimethylaminoethylamino)-4-methylsulfanyl-[1,3,5]triazin-2-yl]-2-methylquinoline-4,6-diamine, which stabilizes DNA in G-quadruplex structures (guanine tetrads); anticancer agents |
| 03/30/2005 | EP1518855A1 Diaminopyrimidinecarboxa mide derivative |
| 03/30/2005 | EP1517905A1 Processes for preparing substituted pyrimidines and pyrimidine derivatives as inhibitors of protein kinases |
| 03/30/2005 | EP1517892A1 Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof |
| 03/30/2005 | CN1602196A Ureas of 2-aminobenzothiazoles as adenosine modulators |
| 03/24/2005 | CA2788502A1 Non-peptide agonists and antagonists of adrenomedullin and gastric releasing peptide |
| 03/23/2005 | EP1515968A2 Quinuclidine derivatives and pharmaceutical compositions containing the same |
| 03/23/2005 | EP1515967A1 2-heteroaryl carboxamides |
| 03/23/2005 | EP1419125A4 Kinetic resolutions of chirat 3- and 3-substituted carboxylic acids |
| 03/22/2005 | US6869946 For therapy of disease or condition in a mammal, wherein the alpha 7 nicotinic acetylcholine receptor is implicated and for therapy of diseases where there is a sensory-gating deficit in a mammal |
| 03/17/2005 | US20050059698 Cognitive and attention deficit symptoms of Alzheimer's, neurodegeneration disease, behavioral or psychological disorders; N-((3R)-1-azabicyclo[2.2.2]oct-3-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide L-malate; including antipsychotic drugs |
| 03/16/2005 | EP1513839A1 3-substituted quinuclidines and their use |
| 03/16/2005 | CN1596247A Lactam derivatives as antagonists for human 11CBY receptors |
| 03/16/2005 | CN1193028C Dual molecules containing peroxide derivative; synthesis and therapeutic applications thereof |
| 03/15/2005 | US6867230 Antibacterial and antiprotozoal agents |
| 03/15/2005 | US6867201 For therapy of abnormal cell growth, such as cancer, in mammals |
| 03/10/2005 | WO2005021495A2 Quaternary salt derivatives of 1,4-diphenylazetidin-2-ones |
| 03/10/2005 | US20050054680 Agonists and antagonists of 5h3-like receptors of invertebrates as pesticides |
| 03/10/2005 | US20050054672 Quinolinone derivatives |
| 03/03/2005 | WO2005019211A2 Biaryl heterocyclic compounds and methods of making and using the same |
| 03/03/2005 | US20050049264 Suppressing growth of abnormal cells; gastric, brain, colon, pancreatic, lung, renal, ovarian and prostatic cancer |
| 03/03/2005 | CA2528089A1 Biaryl heterocyclic compounds and methods of making and using the same |
| 03/01/2005 | US6861526 Contacting compound containing mixture of R- and S-isomers with chiral organic acid in presence of organic solvent and carboxylic acid for converting R-isomer into acid salt of S isomer, reacting chiral ketone with amine, reducing amine |
| 03/01/2005 | US6861420 N-substituted 1,2,4,5-tetrahydro-1H-benzo[d]azepine compounds |
| 03/01/2005 | US6861412 Diphosphate salt of A 4″-substituted-9-deoxo-9A-AZA-9A-homoerythromycin derivative and its pharmaceutical composition |
| 02/24/2005 | WO2005016923A1 Novel quinuclidine derivatives and their pharmaceutical use |