Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704)
10/2009
10/21/2009EP2109609A1 Novel quinuclidine derivative useful in the preparation of mequitazine
10/21/2009EP1608374B9 2-phenoxy- and 2-phenylsulfomamide derivatives with ccr3 antagonistic activity for the treatment of asthma and other inflammatory or immunological disorders
10/15/2009WO2009126806A2 Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase
10/15/2009WO2009087669A3 Palonosetron free base and process for its preparation
10/15/2009US20090258898 Amides of acetic and propionic acids
10/15/2009US20090258854 Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase
10/14/2009EP1877367B1 Acetylene derivatives
10/08/2009WO2009122664A1 Photobase generator
10/08/2009US20090253908 Novel m3 muscarinic acetylchoine receptor antagonists
10/08/2009CA2718488A1 Novel dhsp90 inhibitory carbazole derivatives, compositions containing same, and use thereof
10/06/2009US7598268 Vascular endothelial growth factor; tyrosine kinase inhibitor;angiogenesis inhibitor; anticarcinogenic agents
10/06/2009US7598267 Muscarinic acetylcholine receptor antagonists
10/01/2009US20090247506 Antibacterial agents
09/2009
09/29/2009US7595327 Exo-N-Hydroxy-3-[methyl({4-[(2-methylquinolin-4-yl) methoxy]phenyl}sulfonyl)amino]bicyclo[2.2.1]heptane-2-carboxamide; rheumatoid arthritis (RA), juvenile RA, psoriatic arthritis, ankylosing spondylitis, psoriasis, osteoarthritis, tumor metastasis, sepsis, AIDS, ulcerative colitis, multiple sclerosis
09/24/2009US20090239903 Tetrahydroquinoline analogues as muscarinic agonists
09/23/2009EP2103612A1 Crystalline forms of palonosetron hydrochloride
09/23/2009EP2102200A2 An improved process for the synthesis of solifenacin
09/16/2009EP2100893A1 Aza-bicycloalkyl ethers and their use as alpha7-nachr agonists
09/16/2009CN101535306A Quiniclidine derivatives of (hetero) arylcycloheptanecarboxylic acid as muscarinic receptor antagonists
09/16/2009CN101531658A Cinchona alkaloid quaternary ammonium salt derivatives as well as preparation method and application thereof
09/10/2009US20090227623 Deuterium-enriched palosetron
09/10/2009US20090226411 Chemical derivatives and their application as antitelomerase agents
09/08/2009US7585885 Beta -secretase (BACE); Alzheimer's disease; 2-(R)-[2-(S)-Amino-3-(3,5-difluorophenyl)-1-(S)-hydroxypropyl]-pyrrolidine-1-carboxylic acid tert-butyl ester
09/03/2009US20090221821 Adenosine receptor antagonists and methods of making and using the same
09/03/2009US20090221602 Processes for preparing substituted pyrimidines
09/02/2009EP2094694A1 Quiniclidine derivatives of (hetero) arylcycloheptanecarboxylic acid as muscarinic receptor antagonists
09/02/2009EP2094693A2 A method for the preparation of solifenacin
09/02/2009EP2094269A1 Pyrrolidinanilines
09/01/2009US7582764 quinoline-1-azabicyclo(2.2.2)octane-based catalysts for preparing a chiral, non-racemic beta -cyano ketone; method of kinetic resolution; producing a non-racemic, chiral compound; highly enantioselective C-C bond forming reaction
09/01/2009US7582660 2-thio-substituted imidazole derivatives and their use in pharmaceutics
09/01/2009US7582645 Pyrimidine derivatives for treatment of hyperproliferative disorders
08/2009
08/27/2009US20090216019 Process for Production of Optically Active Quinuclidinols
08/27/2009US20090211038 Hemicyanin styryl thiol/disulfide dye, composition comprising hemicyanin styryl thiol/disulfide dye, and method for lightening keratin materials using hemicyanin styryl thiol/disulfide dye
08/26/2009EP1631569B1 Quinuclidine derivatives binding to mucarinic m3 receptors
08/26/2009EP1590338B1 Modulators of melanocortin receptor
08/26/2009EP1477488B1 Novel optically active compounds, method for kinetic optical resolution of carboxylic acid derivatives and catalysts therefor
08/25/2009US7579362 3-(6-p-Tolyl-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane; treatment of psychotic disorders such as schizophrenia, mania, depression and anxiety; neurodegenerataive disorders such as senile dementia, Alzhelmer's disease and other intellectual impairment disorders
08/25/2009US7579354 3-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro- 1H-purin-8-yl)- bicyclo[2.2.2]oct-1-yl]-propionic acid or pharmaceutically acceptable salts; highly potent and selective diuretics; treatment of cardiac and circulatory disorders, degenerative disorders of central nervous system
08/25/2009US7579342 Pteridine compounds for the treatment of psoriasis
08/25/2009US7579339 Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
08/20/2009US20090209579 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof
08/18/2009CA2392030C Urea compounds having muscarinic receptor antagonist activity
08/18/2009CA2392028C Carbamate derivatives having muscarinic receptor antagonist activity
08/13/2009WO2009099086A1 3-substituted sulfonyl piperazine derivative
08/13/2009WO2009098453A1 Azonia bicycloalkanes as m3 muscarinic acetylcholin receptor antagonists
08/13/2009WO2009068253A3 Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabicyclo [2.2.2]oct-yl ester
08/13/2009US20090203914 Process for the preparation of solifenacin
08/13/2009US20090203913 Asymmetric Friedel-Crafts Alkylations Catalyzed By Bifunctional Cinchona Alkaloids
08/13/2009CA2711399A1 3-substituted sulfonylpiperidine derivative
08/12/2009EP2088148A2 "Process for the preparation of solifenacin"
08/12/2009EP1429771B1 Bicyclic compounds as inhibitors of chemokine binding to us28
08/12/2009CN101506205A Polymorph of (R) -3- (2-hydroxy-2, 2-diphenyl-acetoxy) -1- (isoxazol-3-ylcarbamoyl-methyl) -1-azoni a-bicyclo- [2.2.2] octane bromide
08/12/2009CN100525763C Mono- and bicyclic azole derivatives that inhibit the interaction of ligands with rage
08/06/2009WO2008120080A3 An improved process for the synthesis of solifenacin
08/06/2009US20090198064 Process for preparing quinuclidinium carbamate derivatives
08/05/2009CN101501001A Processes for optical resolution of 1-phenyl-1,2,3,4-tetrahydroisoquinoline
08/05/2009CN100522976C Novel azacyclic ethynyl derivatives
07/2009
07/28/2009US7566727 2-(1-aza-bicyclo[2.2.2]oct-3-yl)-2,3-dihydro-isoindole-1-one/5,6-dihydro-furo[2,3-c] pyrrol-4-one derivative ligands for alpha 7 nicotinic acetylcholine receptor
07/28/2009US7566710 4-((7-chloroquinolin-4-yl)aminoalkyleneamino-)-spiro(cyclohexane-1.5'-1H-4,5,6-trioxaindene )dicitrate; malaria; paraciticides; antiprotozoa agents; Plasmodium; synergistic; chloroquine-resistant; cost efficiency; industrial scale; penetration and activity of artemisine
07/28/2009CA2462453C Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease
07/23/2009WO2009090008A1 Dry powder formulation comprising an anticholinergic drug
07/23/2009WO2009055437A9 (1,4-diaza-bicyclo[3.2.2]non-6-en-4-yl)-heterocyclyl-methanone ligands for nicotinic acetylcholine receptors, useful for the treatment of disease
07/22/2009EP2080508A1 Dry powder formulation comprising an anticholinergic drug
07/22/2009CN101490049A Quinuclidine derivatives as M3 antagonists
07/22/2009CN101490048A Process for manufacturing 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3- phenoxypropyl)-1 -azoniabicyclo[2.2.2]octane bromide
07/22/2009CN100515419C Substituted benzazoles and its application as inhibitors of Raf kinase
07/21/2009USRE40861 4-Trimethylammonium-3-(nonylcarbamoyl)-aminobutyrate; hypoglycemic agents; antidiabetic agents; antiischemic agents; congestive heart failure; obesity
07/16/2009WO2009087664A1 Process for preparing chemically and chirally pure solifenacin base and its salts
07/16/2009WO2009087643A1 Novel crystalline forms of palonosetron hydrochloride
07/16/2009WO2002079207A3 Tri-and bidentate amido ligands prepared by palladium0 coupling and metallation thereof to form metal-amido catalysts
07/16/2009US20090181979 Pharmaceutically acceptable salts of quinolinone compounds having improved pharmaceutical properties
07/15/2009EP2078718A1 N-aryl diazaspiracyclic compounds and methods of preparation and use thereof
07/15/2009CN100513406C Novel quinuclidine derivatives and their use
07/15/2009CN100513387C Novel dibenzo[B,F]oxepine-10-carboxamides and pharmaceutical uses thereof
07/07/2009US7557212 Tricyclic derivatives as LTD4 antagonists
07/07/2009US7557106 inhibitors of FLT-3, Aurora-1, Aurora-2, and Aurora-3 protein kinases; leukemia; N-{4-[4-(5-Methyl-2H-pyrazol-3-ylmethyl)-6-(4-propyl-piperazin-1-yl)-pyrim- idin-2-ylsulfanyl]-phenyl}-propionamide
07/07/2009US7557102 Pyrazolidine-1,2-dicarboxyldiphenylamide derivatives as coagulation factor Xa inhibitors for the treatment of thromboses
07/02/2009US20090170833 Pyrazolyl derivatives, preparation process and intermediates of this process as medicinal products and pharmaceutical compositions containing them
06/2009
06/30/2009US7553851 2-(1-Azabicyclo[2.2.2]oct-3-yl)-N-(7-bromo-1-benzothien-2-yl)acetamide hydrochloride; nicotinic receptor agonists; cognition activators; learning enhancement; nootropic agents; demetia; cholinergic agents; Alzheimer's disease; brain traumas; stroke; attention deficit disorder; schizophrenia
06/30/2009US7553846 2-alkylbenzoxazole carboxamides as 5-HT3 modulators
06/25/2009US20090163496 Antibacterial agents
06/23/2009US7550500 Bicyclic and tricyclic amines as modulators of chemokine receptor activity
06/18/2009WO2009074789A1 Amido-thiophene compounds and their use as 11-beta-hsd1 inhibitors
06/17/2009EP2070930A1 Polycycloalkylpurines as adenosine receptor antagonists
06/17/2009EP1499616B1 Heterocyclic compounds
06/16/2009US7547686 Combretastatin A-3 prodrug
06/16/2009CA2385995C Quinuclidine compound and medicament comprising the compound as active ingredient
06/16/2009CA2202032C Agent for potentiating nerve growth factor activity containing 1,2-ethanediol derivative or salt thereof
06/11/2009WO2009055437A3 (1,4-diaza-bicyclo[3.2.2]non-6-en-4-yl)-heterocyclyl-methanone ligands for nicotinic acetylcholine receptors, useful for the treatment of disease
06/09/2009US7544808 9-[4-[4-[[2-(2,2,2-trifluoroethoxy)benzoyl]amino]-1-piperidinyl]butyl]-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide; non-steroidal modulator of the glucocorticoid receptor, AP-1, and/or NF- kappa B activity, obesity, diabetes, inflammatory and immune diseases
06/09/2009US7544693 Spirofuropyridine aryl derivatives
06/04/2009CA2706565A1 Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabicyclo [2.2.2]oct-3-yl ester
06/03/2009EP2065385A1 Stable crystalline salt of (R)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester
06/03/2009EP2064210A1 Polymorph of (r) -3- (2-hydroxy-2, 2-diphenyl-acetoxy) -1- (isoxazol-s-ylcarbamoyl-methyl) -1-azoni a-bicyclo- [2.2.2] octane bromide
06/03/2009EP1606288B1 Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain
06/03/2009CN100494202C Spirofuropyridine aryl derivatives
05/2009
05/28/2009US20090137810 Synthetic Methods and Intermediates for Stereoisomeric Compounds Useful for the Treatment of Gastrointestinal and Central Nervous System Disorders
05/26/2009US7538121 Vanilloid receptor modulators
05/26/2009US7538111 N(2-hydroxyethyl)-4-methoxy-N,2,6-trimethylbenzene- sulphonamide; analgesic, antiinflammatory agent; hyperalgesia and major algesia connected with other pathological conditions such as cancer
05/21/2009US20090131501 Alzheimer's disease; administering orally (+) phenserine; phenserine tartrate; racemic or enantiomerically pure; not toxic in a wide range of dosages
1 ... 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 ... 58