| Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704) |
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| 12/16/2008 | CA2398887C 2,4,di(hetero-)arylamino(-oxy)-5-substituted pyrimidines as antineoplastic agents |
| 12/16/2008 | CA2285817C Novel basic derivatives of benz[e]isoindol-1-ones and pyrrolo[3,4-c] quinolin-1-ones with 5-ht3-antagonistic activity, their preparation and their therapeutic use |
| 12/10/2008 | EP1396487B1 Phenylpyridine carbonyl piperazine derivative |
| 12/09/2008 | US7462722 3-quinuclidinone or the salt reacted with hydrogen in the presence of a basic compound, a complex of a transition metal with ligand such as 2,2'-bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl- and optically active 1,2-butanediamines |
| 12/09/2008 | US7462628 Preventives/remedies for urinary disturbance |
| 12/04/2008 | WO2008146774A1 Tetrahydroisoquinolin-1-one derivative or salt thereof |
| 12/04/2008 | WO2008145243A1 Pyridazinone derivatives |
| 12/04/2008 | CA2688518A1 Pyridazinone derivatives for use in the treatment of a disease which is influenced by inhibiton of met kinase |
| 12/04/2008 | CA2688326A1 Tetrahydroisoquinolin-1-one derivative or salt thereof |
| 12/03/2008 | EP1997495A1 2-phenoxy- and 2-phenylsulfanyl-benzenesulfonamide derivatives with ccr3 antagonistic activity for the treatment of asthma and other inflammatory or immunological disorders |
| 12/03/2008 | EP1996585A2 Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
| 12/03/2008 | EP1480954B1 Vanilloid receptor modulators |
| 12/03/2008 | EP1028961B3 Pleuromutilin derivatives as antimicrobials |
| 12/03/2008 | CN101316828A Method for preparing N-triazine radical ammonium salt |
| 12/03/2008 | CN101314601A Preparation process of high-purity palonosetron Hcl |
| 11/27/2008 | US20080294289 Preparation and Use of Alkylating Agents |
| 11/26/2008 | EP1994015A1 Dibenzyl amine derivatives as cetp inhibitors |
| 11/26/2008 | CN101312968A Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof |
| 11/25/2008 | US7456206 Biaryl heterocyclic compounds and methods of making and using the same |
| 11/25/2008 | CA2449922C Pharmaceutical composition for therapy of interstitial cystitis |
| 11/20/2008 | WO2008062282A3 An improved process for the synthesis of solifenacin |
| 11/20/2008 | US20080287680 Solifenacin Succinate-Containing Composition |
| 11/20/2008 | US20080287487 Muscle relaxants; respiratory system disorders; asthma; COPD; emphysema; bronchitis |
| 11/18/2008 | US7452997 Tetrahydro-indazole cannabinoid modulators |
| 11/18/2008 | US7452911 Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds |
| 11/18/2008 | US7452904 1-alkyl-1-azoniabicyclo' 2.2.2 octane carbamate derivatives and their use as muscarinic receptor antagonists |
| 11/18/2008 | CA2331850C Method of preparing carboxylic acid derivatives and condensing agent comprising a quaternary ammonium salt |
| 11/12/2008 | EP1989185A1 Therapeutic compounds |
| 11/11/2008 | US7449489 e.g. isopropyl [({2-[5-[2-(2-azabicyclo[2.2.2]oct-2-yl)- 1,1-dimethyl-2-oxoethyl]-2-(3,5-dimethylphenyl)-1H-indol-3-yl]propyl }amino)(3-pyridin-4-ylpyrrolidin-1-yl)methylene]carbamate; gonadotrophin releasing hormone antagonists; anticarcinogenic agent; breast, prostate, uretus cancer |
| 11/11/2008 | US7449478 Treatment of peroxisome proliferation activated receptor diseases such as diabetes, skin disorders or high blood pressure |
| 11/11/2008 | US7449457 Substituted heterocyclic carboxamides with antithrombotic activity |
| 11/11/2008 | US7449456 signal transducer and activator of transcription-6 inhibitors; asthma, COPD, respiratory, inflammatory and allergic diseases; compounds have less suppressive effect on immunological functions; 4-[(2,5 -difluorobenzyl) amino]-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5 -carboxamide |
| 11/06/2008 | WO2008132679A1 Bridged six-membered ring compounds |
| 11/06/2008 | US20080275003 Phospholipase inhibitor; prevention or therapy of microbial infection; bactericides; fungicides; viricides; parasiticides; using quaternary or phosphonium group containing compounds |
| 11/06/2008 | CA2683866A1 Bridged six-membered ring compounds |
| 11/05/2008 | EP1988075A1 Pyrrole derivative or salt thereof |
| 11/05/2008 | EP1987029A1 Enantiopure quinuclidinyloxy pyridazines and their use as nicotinic acetylcholine receptor ligands |
| 11/05/2008 | EP1987006A1 Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments |
| 11/05/2008 | EP1608374B1 2-phenoxy- and 2-phenylsulfomamide derivatives with ccr3 antagonistic activity for the treatment of asthma and other inflammatory or immunological disorders |
| 11/05/2008 | EP1319000B1 Use of 1-azabicyclo 2.2.2 octan-3-one derivatives for treating cancer tumors |
| 11/05/2008 | CN101298433A 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy |
| 10/30/2008 | WO2008129054A2 Heterocyclic compounds with affinity to muscarinic receptors |
| 10/30/2008 | US20080269221 Antibacterial agents |
| 10/30/2008 | US20080269207 Anticancer agents; such as 4-acetylamino-1H-pyrazole-3-carboxylic acid (4-fluoro-phenyl)-amide |
| 10/30/2008 | CA2682994A1 Heterocyclic compounds with affinity to muscarinic receptors |
| 10/29/2008 | EP1660474B1 Substituted thiophenes and uses thereof |
| 10/28/2008 | US7442794 Stereoisomers ; reacting with Lewis acid; purification |
| 10/23/2008 | US20080262030 Drug for psychological and central nervous system disorders |
| 10/23/2008 | US20080262023 Aminomethyl Azaadamantane Derivatives and Methods of Use Thereof |
| 10/22/2008 | EP1417196B1 Dna-pk inhibitors |
| 10/21/2008 | US7439256 (Arylamidoaryl) cyanoguanidine compounds |
| 10/16/2008 | US20080255135 1-Aza-bicyclo[2.2.2]octane and 1-aza-bicyclo[2.2.1]heptane derivatives; psychotic, psychological, nervous system and neurodegenerative disorders; nicotinic receptor mediated diseases |
| 10/16/2008 | US20080255114 2-aminobenzoxazole carboxamides as 5ht3 modulators |
| 10/15/2008 | EP1980252A2 Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders |
| 10/15/2008 | EP1411940B1 Bridged piperidine derivatives as melanocortin receptor agonists |
| 10/14/2008 | US7435742 potent antagonists of M3 muscarinic receptors; chronic obstructive pulmonary disease; bronchitis, bronchial hyperreactivity, asthma, cough and rhinitis; gastrointestinal disorders; incontinenc; [2-(3,4-Dimethoxyphenyl)ethyl]-(5-methylfuran-2-ylmethyl)carbamic acid (3R)-1 -azabicyclo[2.2.2]oct-3-yl ester |
| 10/09/2008 | WO2008120080A2 An improved process for the synthesis of solifenacin |
| 10/09/2008 | US20080249312 Process for the preparation of 2-methylspiro(1,3-oxathiolane-5,3')quiniclidine |
| 10/09/2008 | US20080247963 Quinuclidine Compounds Having Quaternary Ammonium Group, Its Preparation Method and Use as Blocking Agents of Acetylcholine |
| 10/09/2008 | CA2682381A1 An improved process for the synthesis of solifenacin |
| 10/08/2008 | EP1633348B1 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES |
| 10/07/2008 | US7432400 sun protection agents; diketone |
| 10/07/2008 | US7432379 3-Amido-5-substituted pyrazole derivatives and related compounds useful as bradykinin B1 receptor antagonists to relieve adverse symptoms in mammals mediated, at least in part, by bradykinin B1 receptor including pain, inflammation, septic shock, scarring process |
| 10/07/2008 | US7432280 3-aminopiperidines and 3-aminoquinuclidines as inhibitors of monoamine uptake |
| 10/04/2008 | CA2584349A1 Process for the preparation of 2-methylspiro(1,3-oxathiolane-5,3') quiniclidine |
| 10/02/2008 | US20080242697 Reacting 3-quinuclidinol with 1,3-carbonyldi(1,2,4triazole) in solvent; then 1,2,3,4-tetrahydroisoqionoline; isolation; purification |
| 10/01/2008 | EP1973904A2 Muscarinic agonists and methods of use thereof |
| 09/30/2008 | US7429664 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof |
| 09/25/2008 | US20080234316 Quinuclidine Amide Derivatives |
| 09/18/2008 | WO2008112900A1 Dibenzo[b,f][1,4]oxazapine compounds |
| 09/18/2008 | US20080227809 hexaquis(3-phenyl-propylamine) decavanadate (V); particularly insulin-resistant diabetes; insulin mimickers |
| 09/18/2008 | US20080227785 BEC 1 potassium channel inhibitors, used to treat dementia and learning disorders; e.g., N-(4-fluorophenyl)-N'-isopropyl-N''-phenyl-1,3,5-triazine-2,4,6-triamine hydrochloride |
| 09/18/2008 | US20080227683 Compounds Having Antitumor Activity |
| 09/18/2008 | CA2678897A1 Dibenzo[b,f][1,4]oxazapine compounds |
| 09/17/2008 | CN101268071A Novel 1-aza bicycloalkyl derivatives for the treatment of psychotic and neurodegenerative disorders |
| 09/17/2008 | CN100418964C Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine |
| 09/16/2008 | US7425561 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| 09/12/2008 | WO2008107545A1 Novel quinuclidine derivative useful in the preparation of mequitazine |
| 09/12/2008 | CA2675118A1 Novel quinuclidine derivative useful in the preparation of mequitazine |
| 09/11/2008 | US20080221331 Azabicyclo[3.3.1]nonane N-oxyl having an N-oxyl group incorporated; pharmaceuticals, perfume and liquid crystal; low environmental burden, can be supplied in a large amount at a low cost |
| 09/11/2008 | US20080221330 14-{(3S,4S)-1-azabicyclo[2.2.1]heptane-3-carbonyl}carbamoyl-12-desethenyl-3-methoxy-11-O-methoxymethyl-11-oxo-12-[2-propene-3-yl]-4-epimutilin; strong antimicrobial activity against abroad spectrum of Gram-positive or Gram-negative bacteria |
| 09/11/2008 | US20080221155 Novel quinuclidine derivatives and medicinal compositions containing the same |
| 09/10/2008 | EP1966197A2 Processes for preparing palonosetron salts |
| 09/09/2008 | US7423061 Anticarcinogenic agents; tert-butyl 3-{[(2-[(aminocarbonyl)amino]-5-{4-[2-(diethylamino)ethoxy]phenyl}-3-thienyl)carbonyl]amino}piperidine-1-carboxylate |
| 09/09/2008 | CA2412047C Shortened synthesis of 3,3-diarylpropylamine derivatives |
| 09/04/2008 | US20080214870 Method of Preparing Amine Stereoisomers |
| 09/04/2008 | US20080214602 N-Biarylamides |
| 09/04/2008 | US20080214601 2-alkylbenzoxazole carboxamides as 5ht3 modulators |
| 09/04/2008 | US20080214600 Quaternized Quinuclidine Esters |
| 09/04/2008 | US20080214591 N-Aryl Diazaspirocyclic Compounds and Methods of Preparation and Use Thereof |
| 09/03/2008 | EP1963285A1 Bradykinin 1 receptor antagonists |
| 09/03/2008 | EP1730112B1 3-((hetero)arylsulfonyl)-8'[ (aminoalkyl)oxy]quinolines as 5-ht6 receptor antagonists for the treatment of cns disorders |
| 09/03/2008 | EP1262477B1 Anti-acid-fast bacterial agents containing pyridonecarboxylic acids as the active ingredient |
| 09/03/2008 | CN101258151A Synthetic methods and intermediates for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders |
| 09/03/2008 | CN101255162A Adenosine receptor antagonists and methods of making and using the same |
| 09/03/2008 | CN101255157A Crystal system of chlorhydric acid palonosetron and preparation method thereof |
| 08/27/2008 | EP1960397A2 Crystalline forms of palonosetron hydrochloride |
| 08/27/2008 | EP1349858B1 Agents useful for reducing amyloid precursor protein and treating demantia and methods of use thereof |
| 08/26/2008 | US7417152 4-Bromo-5-(2-chloro-benzoylamino)-1H-pyrazole-3-carboxylic acid (2-pyrrolidin-1-yl-ethyl)-amide; 5-(2-chlorobenzoylamino)-1H-pyrazole-3-carboxylic acid {2-[4-(4,5-dihydro-1H-imidazol-2-yl)-phenyl]ethyl}amide; useful for the moderation of pain, septic shock, and scarring |
| 08/26/2008 | US7417050 Cognition activators; Alzheimer's disease; attention deficit disorders; Parkinson's disease; Huntington's disease; neurodegenerative disease |