| Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704) |
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| 03/09/2010 | US7674823 DNA-PK inhibitors |
| 03/09/2010 | US7674797 2-phenoxy- and 2-phenylsulfonamide derivatives with CCR3 antagonistic activity for the treatment of asthma and other inflammatory or immunological disorders |
| 03/09/2010 | US7674794 Fused bicycloheterocycle substituted quinuclidine derivatives |
| 03/09/2010 | CA2407972C Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists |
| 03/04/2010 | WO2010024430A1 2,4-diaminopyrimidine compound |
| 03/04/2010 | US20100056565 Heterocyclic Derivatives as M3 Muscarinic Receptors |
| 03/04/2010 | US20100056502 Compounds |
| 03/04/2010 | CA2735730A1 2,4-diaminopyrimidine compound |
| 03/02/2010 | US7671088 Water-soluble etoposide analogs and methods of use thereof |
| 03/02/2010 | US7671049 1-{3-[(6-amino-5-nitropyridin-2-yl)amino]propyl}-4-(2,4-dichlorophenyl)-N-[(1S)-2-hydroxy-1-methylethyl]-1H-pyrrole-3-carboxamide; Antidiabetic, hypotensive, antiischemic, anticarcinogenic agents; Alzheimer*s disease, obesity, polycystic ovary syndrome; brain, neurodegenerative and autoimmune diseases |
| 02/24/2010 | EP2156824A1 Composition of solifenacin or salt thereof for use in solid formulation |
| 02/24/2010 | EP2155199A2 Novel palonosetron salts and processes for preparation and purification thereof |
| 02/23/2010 | US7667040 Azacyclic ethynyl derivatives |
| 02/23/2010 | CA2329930C Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase |
| 02/18/2010 | US20100041887 Quinuclidine derivatives binding to mucarinic m3 receptors |
| 02/18/2010 | US20100039688 6-(biphenyl-ester)-3h-naphtho[2,1-b]pyrans as photochromic dichroic dyes and optical article containing them |
| 02/17/2010 | EP2154136A1 Quinuclidine carbonate derivatives and medicinal compositions thereof |
| 02/11/2010 | WO2010015324A1 Quinuclidine carbonate derivatives and medicinal composition thereof |
| 02/11/2010 | US20100035922 Quinuclidine carbonate salts and medicinal composition thereof |
| 02/11/2010 | US20100034741 Imaging agents and methods of imaging alpha7-nicotinic cholinergic receptor |
| 02/11/2010 | CA2733380A1 Quinuclidine carbonate derivatives and medicinal composition thereof |
| 02/10/2010 | EP2150543A2 Heterocyclic compounds with affinity to muscarinic receptors |
| 02/10/2010 | EP2150539A1 Pyridazinone derivatives |
| 02/10/2010 | CN101643474A Preparation method of 3-quininone |
| 02/10/2010 | CN100588657C Novel azabicyclic aryl derivatives and their medical use |
| 02/09/2010 | US7659282 Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders |
| 02/09/2010 | CA2557576C Novel benzothiazepine and benzothiepine compounds |
| 02/04/2010 | WO2010012459A2 A process for the preparation of solifenacin salts and their inclusion into pharmaceutical dosage forms |
| 02/04/2010 | US20100029944 Process for the Synthesis of Solifenacin |
| 02/04/2010 | US20100029713 Quiniclidine derivatives of (hetero) arylcycloheptanecarboxylic acid as muscarinic receptor antagonists |
| 01/28/2010 | WO2009138707A9 Quinuclidine derivatives as muscarinic m3 receptor antagonists |
| 01/27/2010 | CN101633657A Preparation method of palonosetron and palonosetron hydrochloride and injection |
| 01/27/2010 | CN100584840C Substituted heterocyclic compounds and uses thereof |
| 01/26/2010 | US7652010 Azabicyclic aryl derivatives and their medical use |
| 01/21/2010 | WO2010008117A1 Cinchona-based bifucntional organocatalysts and method for preparing chiral hemiesters using the same |
| 01/21/2010 | US20100016351 Nicotinic alpha-7 receptor ligands and preparation and uses thereof |
| 01/20/2010 | EP1828179B1 Nicotinic alpha-7 receptor ligands against cns-related diseases |
| 01/19/2010 | US7649094 Reacting diastereomeric mixtures of chiral carboxylic acid compounds with nucleophiles |
| 01/14/2010 | US20100010225 Isoquinuclidine derivative and method for manufacturing 1-cyclohexene-1-carboxylic acid derivative using the same |
| 01/13/2010 | EP2142540A2 An improved process for the synthesis of solifenacin |
| 01/13/2010 | EP2141990A1 11beta-hsd1 active compounds |
| 01/13/2010 | EP1987029B1 Enantiopure quinuclidinyloxy pyridazines and their use as nicotinic acetylcholine receptor ligands |
| 01/12/2010 | US7645599 Specific, asymmetric reduction of 3-quinuclidinone using tropinone reductase-I in the presence of a reduced coenzyme to produce (R)-3-quinuclidinol; high optical purity |
| 01/12/2010 | CA2399818C Preventive and therapeutic medicament for gastroesophageal reflux disease |
| 01/07/2010 | WO2010002675A2 Quinine sulfate/bisulfate solid complex; methods of making; and methods of use thereof |
| 12/31/2009 | US20090326230 Process for preparing solifenacin and its salts |
| 12/31/2009 | US20090326004 Muscarinic receptor antagonists |
| 12/30/2009 | CN101613349A Preparation method of S-3-aminoquinuclidine dihydrochloride |
| 12/30/2009 | CN101613321A Mono- and bicyclic azole derivatives that inhibit the interaction of ligands with rage |
| 12/30/2009 | CN101613310A Method of preparing amine stereoisomers |
| 12/29/2009 | US7638536 N-[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl]-3-fluoro-4-hydroxybenzamide; nonpeptide c-mpl ligand; low immunogenicity; proliferate human c-mpl-Ba/F3 cells; increase platelets by promoting the formation of megakaryocytic colonies; orally |
| 12/29/2009 | US7638529 Heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents |
| 12/29/2009 | US7638515 improved selectivity and pharmacokinetic properties; 6-Fluoro-1-[(1 H-indazol-4-yl)amino]-4,4-dimethyl-2-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalene-2,5-diol; cyclization of imines |
| 12/23/2009 | WO2009153536A1 1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists |
| 12/23/2009 | CN101610813A Quinuclidinol derivatives as muscarinic receptor antagonists |
| 12/22/2009 | CA2414514C Carbamates derived from arylalkylamines |
| 12/17/2009 | WO2009150141A1 Azabicyclooctyl-quinazolone derivatives useful as nicotinic acetylcholine receptor modulators |
| 12/16/2009 | CN101605784A Aza-bridged-ring compound |
| 12/09/2009 | EP2130830A1 Muscarinic receptor antagonists |
| 12/09/2009 | EP1519939B1 N-aryl diazaspiracyclic compounds and methods of preparation and use thereof |
| 12/09/2009 | CN101597286A Organic catalyst containing primary amine, tertiary amine and urea or thiourea and preparation method thereof |
| 12/09/2009 | CN101597285A 3-quinine ester quaternary ammonium salt and application in pharmacy |
| 12/09/2009 | CN101597262A Mono- and bicyclic azole derivatives that inhibit the interaction of ligands with rage |
| 12/08/2009 | US7629468 Neuroprotectants, analgesics or anticonvulsants |
| 12/08/2009 | US7629466 Preparing (R)-quinuclidin-3-yl 6-((3S,4R)-4-(4-amino-5-chloro-2-methoxybenzamido)-3-methoxypiperidin-1-yl)hexanoate; ethyl 4-amino-3-methoxypiperidine-1-carboxylate; benzylation; chiral salt; basification; ethyl 6-bromohexanoate; R)-quinuclidin-3-ol; deprotect; 4-amino-5-chloro-2-methoxybenzoic acid |
| 12/03/2009 | WO2009145323A1 Method for oxidizing alcohol by using polycyclic compound |
| 12/03/2009 | WO2009122034A3 Novel dhsp90 inhibitory carbazole derivatives, compositions containing same, and use thereof |
| 12/03/2009 | US20090298825 Bicycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof |
| 12/02/2009 | EP1663220B1 Novel process for the preparation of pleuromutilin derivatives |
| 12/02/2009 | CN100564381C N-aryl diazaspiracyclic compounds and methods of preparation and use thereof |
| 11/26/2009 | WO2009142522A1 Process for preparation of solifenacin and/or the pharmaceutically acceptable salts thereof of high pharmaceutical purity |
| 11/25/2009 | CN101585835A Preparation method and application of bencycloquidium bromide optical isomer and composition of bencycloquidium bromide optical isomer |
| 11/19/2009 | WO2009139710A1 Quinuclidine derivatives and their use as muscarinic receptor antagonists |
| 11/19/2009 | WO2009139709A1 Quinuclidine derivatives and their use as muscarinic receptor antagonists for the treatment of asthma and chronic obstructive pulmonary disease (copd) |
| 11/19/2009 | WO2009139002A2 An improved process for the preparation of solifenacin and its pharmaceutically acceptable salts thereof |
| 11/19/2009 | WO2009138707A1 Quinuclidine derivatives as muscarinic m3 receptor antagonists |
| 11/19/2009 | US20090286771 2-Phenoxy- and 2-Phenylsulfonamide Derivatives with CCR3 Antagonistic Activity for the Treatment of Inflammatory or Immunological Disorders |
| 11/19/2009 | CA2723981A1 New compounds 273 |
| 11/18/2009 | EP2119716A1 Aza-bridged-ring compound |
| 11/18/2009 | EP2044067B1 Process for manufacturing 3(r)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3- phenoxypropyl)-1 -azoniabicyclo[2.2.2]octane bromide |
| 11/18/2009 | EP1184379B1 Chromene compound |
| 11/17/2009 | US7619089 Formulations and use of e.g. 2-chloro-N-(8 alpha ,9S)cinchonan-9-yl)-3-trifluoromethyl-benzamide hydrochloride for treating pain, Parkinson's disease, epilepsy, sleep apnea, alcoholism, psychological disorders, migraines |
| 11/17/2009 | US7618978 Amides as BACE inhibitors |
| 11/17/2009 | US7618961 A sulfonylamino-tetrahydro(1,3)thiazolo(5,4-c)pyridinyl or benzothiazole derivatives, for treating diabetes, syndrome X, obesity, glaucoma, hyperlipidemia, hyperglycemia, hyperinsulinemia, osteoporosis, tuberculosis, dementia |
| 11/12/2009 | WO2009136405A1 High purity palonosetron base and its solid state characteristics |
| 11/12/2009 | US20090281100 Benzimidazole quinolinones and uses thereof |
| 11/12/2009 | US20090281072 Diaminopyrimidinecarboxamide Derivative |
| 11/11/2009 | EP1537104B1 Aza-bicycloalkyl ethers and their use as alpha7-nachr agonists |
| 11/04/2009 | EP1499311B1 Substituted benzazoles and use thereof as raf kinase inhibitors |
| 11/03/2009 | US7612094 Tri-substituted heteroaryls and methods of making and using the same |
| 11/03/2009 | US7612054 Dibenzo[b,f]oxepine-10-carboxamides and pharmaceutical uses thereof |
| 11/03/2009 | CA2443724C Novel, arylsusfonamide compounds for the treatment of obesity, type ii diabetes and cns-disorders |
| 10/29/2009 | WO2009131065A1 Long-chain fatty acid elongation enzyme inhibitor comprising arylsulfonyl derivative as active ingredient |
| 10/29/2009 | US20090270369 Bicycloamine derivatives |
| 10/29/2009 | CA2722075A1 Long-chain fatty acyl elongase inhibitor comprising arylsulfonyl derivative as active ingredient |
| 10/27/2009 | US7608710 Including polyether substituents including pendant alkoxy fluoroalkyl groups; for wetting, leveling and flow agents in solvent-borne coating systems |
| 10/27/2009 | US7608618 1-(2,2,2-trifluoroethanoyl)pyrrolidine-2-carboxylic acid [4-methoxy-3-(3-pyrazin-2-yl-ureido)phenyl]-amide; 4-Methoxy-N-(3-methylamino-propyl)-3-(3-pyrazin-2-yl-ureido)-benzamide; checkpoint kinase Chk1 inhibitor; chemosensitizing agents useful in the treatment of diseases related to DNA damage |
| 10/27/2009 | CA2465534C Agents useful for reducing amyloid precursor protein and treating dementia and methods of use thereof |
| 10/27/2009 | CA2381165C Novel quinuclidine derivatives and medicinal compositions containing the same |
| 10/22/2009 | US20090264461 Polymorph of (R)-3- (2-Hydroxy-2, 2-Diphenyl -Acetoxy) -1- (Isoxazol-s-ylcarbamoyl-methyl)-1-Azoni A-Bicyclo-[2.2.2] Octane Bromide |