| Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704) |
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| 08/25/2005 | WO2005077914A1 PYRIDAZINONE UREAS AS ANTAGONISTS OF α4 INTEGRINS |
| 08/25/2005 | WO2005077899A2 Amino-substituted tricyclic derivatives and methods of use |
| 08/25/2005 | US20050187242 9-[4-[4-[[2-(2,2,2-trifluoroethoxy)benzoyl]amino]-1-piperidinyl]butyl]-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide; non-steroidal modulator of the glucocorticoid receptor, AP-1, and/or NF- kappa B activity, obesity, diabetes, inflammatory and immune diseases |
| 08/25/2005 | CA2555884A1 Amino-substituted tricyclic derivatives and methods of use |
| 08/25/2005 | CA2555594A1 Pyridazinones as antagonists of a4 integrins |
| 08/25/2005 | CA2555227A1 Pyridazinone ureas as antagonists of .alpha.4 integrins |
| 08/24/2005 | EP1565187A2 Methods of treating cancer and related methods |
| 08/24/2005 | CN1659165A Quinolinone derivatives |
| 08/24/2005 | CN1659154A Method of preparing amine stereoisomers |
| 08/24/2005 | CN1658866A Tri-substituted heteroaryls and methods of making and using the same |
| 08/18/2005 | WO2005075474A1 Composition containing solifenacin succinate |
| 08/18/2005 | WO2005075473A1 Process for preparation of 1-(2s,3s)-2-benzhydr yl-n-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amine |
| 08/18/2005 | US20050182040 Benzamide derivatives |
| 08/18/2005 | CA2558877A1 Solifenacin succinate-containing composition |
| 08/18/2005 | CA2554360A1 Process for preparation of 1-(2s,3s)-2-benzhydryl-n-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amine |
| 08/17/2005 | EP1562959A2 Compounds having both alpha7 nachr agonist and 5ht antagonist activity for treatment of cns diseases |
| 08/17/2005 | CN1656093A 3-substituted quinuclidines and their use |
| 08/17/2005 | CN1655779A Substituted benzazoles and methods of their use as inhibitors of Raf kinase |
| 08/16/2005 | US6930107 treating obesity, overweight condition, hyperlipidemia, thyroid disease, hypothyroidism, thyroid cancer and related disorders |
| 08/11/2005 | WO2005072132A2 TRICYCLIC MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-κB ACTIVITY AND USE THEREOF |
| 08/11/2005 | WO2005053663A3 Norepinephrine reuptake inhibitors useful for treatment of cognitive failure |
| 08/11/2005 | US20050176760 and tumors; imino-, thiocarbonyl- or hydroxyimino-substituted N-heterocyclic amide compounds such as 2-(3-aminomethylphenylamino)-N-[3-chloro-4-(2-hydroxyiminopyrrolidin-1-yl)phenyl]-2-phenylacetamide |
| 08/11/2005 | US20050176757 For example, 6-[4-(4-Amino-5-chloro-2-methoxy-benzoylamino)-3-methoxy-piperidin-1-yl]-hexanoic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester; for treatment of gastrointestinal disorders including gastroparesis, gastroesophageal reflux |
| 08/11/2005 | US20050176756 Cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters; treating pain, neurodegeneration, inflammation, and drug or alcohol withdrawal symptoms; 3-benzimidazole, indole or triazole substituted |
| 08/11/2005 | US20050176755 Aza-bridged-bicyclic amino acid derivatives as alpha4 integrin antagonists |
| 08/11/2005 | DE102004003811A1 Substituierte N-Cyclohexylimidazolinone, Verfahren ihrer Herstellung und ihre Verwendung als Arzneimittel Substituted N-Cyclohexylimidazolinone, processes for their preparation and their use as medicaments |
| 08/10/2005 | EP1560817A1 Methods and compositions of novel triazine compounds |
| 08/10/2005 | EP1395265A4 Combretastatin a-3 prodrug |
| 08/04/2005 | WO2005070898A1 Substituted n-cyclohexyl imidazolinones having an mch-modulatory effect |
| 08/04/2005 | WO2005051917B1 Pyrazolyl derivatives in the form of drugs for treating acute or chronic neuronal regressions |
| 08/04/2005 | US20050171345 Pteridine compounds for the treatment of psoriasis |
| 08/04/2005 | US20050171154 Carboxylic acid amides |
| 08/04/2005 | US20050171102 Semicarbazide derivatives for combating thromboembolic diseases |
| 08/04/2005 | US20050171079 2,7-bis-[(3R)-1-azabicyclo[2.2.2]octan-3-yloxy]-fluoren-9-one; 2,7-bis[(2R)-azetidin-2-ylmethoxy]-fluoren-9-one; alpha 7 Nicotinic acetylcholine receptors ligands; cognitive disorder, neurodegeneration, and neurodevelopmental disorders |
| 08/04/2005 | US20050171078 Cholinergic ligands at the nicotinic acetylcholine receptors; diseases related to the cholinergic system; neurodegenerative disorders; pain; antiinflammatory; diagnostic or monitoring tools using labelled forms; 3-Phenyletynyl-quinuclidin-2-ene |
| 08/04/2005 | DE20122417U1 New quinuclidine N-phenylcarbamate derivatives, are selective muscarinic receptor antagonists useful e.g. for treating urinary incontinence, irritable bowel syndrome or respiratory disorders |
| 08/04/2005 | CA2554233A1 Substituted n-cyclohexyl imidazolinones having an mch-modulatory effect |
| 08/03/2005 | EP1558610A2 Substituted aminoquinuclidine compounds and their use as delta-opioid receptor ligands |
| 08/03/2005 | EP1558600A1 Selected cgrp antagonists, method for production and use thereof as medicament |
| 08/03/2005 | EP1558578A1 Novel alkyne compounds having an mch antagonistic effect and medicaments containing these compounds |
| 08/03/2005 | EP1558252A2 Substituted furo 2,3-b] pyridine derivatives |
| 08/03/2005 | CN1649884A Novel azacyclic ethynyl derivatives |
| 08/02/2005 | CA2254972C Process for the preparation of 1-alkoxycarbonyl-3-phenylpropyl derivatives |
| 08/02/2005 | CA2132537C Basic derivatives of glutamic acid and aspartic acid as gastrin or cholecystokinin antagonists |
| 07/28/2005 | WO2005068461A1 Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| 07/28/2005 | US20050165240 Chemical intermediates for production of sibutramine |
| 07/28/2005 | US20050165005 Pyrazolyl derivatives, preparation process and intermediates of this process as medicinal products and pharmaceutical compositions containing them |
| 07/27/2005 | EP1556379A2 Chemical compounds |
| 07/27/2005 | EP1556348A1 Indolylalkylamino-methylidenecarbamate derivatives useful as gnrh antagonists |
| 07/26/2005 | US6921765 1-Azabicyclo[2.2.2]octan-3-one derivatives and maleimide derivatives and their use for treating cancer tumors |
| 07/21/2005 | WO2005066168A1 Spirocyclic quinuclidinic ether derivatives |
| 07/21/2005 | WO2005066167A2 3-quinuclidinyl heteroatom bridged biaryl derivatives |
| 07/21/2005 | WO2005066166A2 3-quinuclidinyl amino-substituted biaryl derivatives |
| 07/21/2005 | WO2005066163A2 Thiophene derivatives as chk 1 inihibitors |
| 07/21/2005 | US20050159597 Such as 4'-(1-azabicyclo[2.2.2]oct-3-yloxy)-1,1'-biphenyl-3-amine; nicotinic acetylcholine receptor modulators; for treatment of attention deficit disorder, Alzheimer*s disease, or AIDS |
| 07/21/2005 | CA2549979A1 3-quinuclidinyl heteroatom bridged biaryl derivatives |
| 07/21/2005 | CA2549976A1 3-quinuclidinyl amino-substituted biaryl derivatives |
| 07/21/2005 | CA2549962A1 Spirocyclic quinuclidinic ether derivatives |
| 07/20/2005 | CN1642580A Radiolabelled quinoline and quinolinone derivatives and their use as metabotropic glutamate receptor ligands |
| 07/19/2005 | US6919359 Azabicyclic-substituted-heteroaryl compounds for the treatment of disease |
| 07/14/2005 | WO2004113277A8 Methods and compositions for treating amyloid-related diseases |
| 07/14/2005 | US20050154232 Nitrosation of the diphenylamine with an alkali metal nitrite in an acidic medium; the nitrosodiphenylamines increase the bioavailability of endothelial nitrogen monoxide; the diphenylamines are used as antioxidants and free radical scavengers; insulin resistance |
| 07/14/2005 | US20050154209 Novel optically active compounds, method for kinetic optical resolution of carboxylic acid derivatives and catalysts therefor |
| 07/14/2005 | US20050154045 E.g., N-[4-(2-Thienyl)phenyl]-1-azabicyclo[2.2.2]octane-3-carboxamide hydrochloride; treatment of impairments of perception, concentration, learning and/or memory |
| 07/14/2005 | US20050153977 N-[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl]-3-fluoro-4-hydroxybenzamide; nonpeptide c-mpl ligand; low immunogenicity; proliferate human c-mpl-Ba/F3 cells; increase platelets by promoting the formation of megakaryocytic colonies; orally |
| 07/13/2005 | EP1551833A1 Process for the preparation of (s,s)-cis-2-benzhydryl-3-benzylaminoquinuclidine |
| 07/13/2005 | EP1235802B1 Carbamate derivatives having muscarinic receptor antagonist activity |
| 07/13/2005 | EP1144364B1 Multicyclic compounds which inhibit leukocyte adhesion mediated by vla-4 |
| 07/13/2005 | EP0977755B1 Heterocyclic compounds and their preparation and use |
| 07/13/2005 | CN1639157A 2-acylaminothiazole derivative or salt thereof |
| 07/13/2005 | CN1639141A New thiadiazoles and oxadiazoles and their use as phosphodiesterase-7 inhibitors |
| 07/13/2005 | CN1639126A Nitrosodiphenylamine derivatives and their pharmaceutical use against oxidative stress pathologies |
| 07/13/2005 | CN1638633A Agonists and antagonists of 5h3-like receptors of invertebrates as pesticides |
| 07/13/2005 | CN1636983A Substituted heterocyclic compounds |
| 07/12/2005 | US6916828 Irritiable bowel syndrome; respiartory system disorders; antihistamines; gastrointestinal disorders |
| 07/07/2005 | WO2005061495A1 Nicotinic acetylcholine receptor ligands |
| 07/07/2005 | WO2005061494A1 Nicotinic acetylcholine receptor ligands |
| 07/07/2005 | CA2550847A1 Nicotinic acetylcholine receptor ligands |
| 07/07/2005 | CA2550844A1 Nicotinic acetylcholine receptor ligands |
| 06/30/2005 | US20050143393 Bactericides; infection therapy; topical administering |
| 06/29/2005 | CN1633290A Mono- and bicyclic azole derivatives that inhibit the interaction of ligands with rage |
| 06/28/2005 | US6911543 Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease |
| 06/28/2005 | US6911542 Pyrazino[1′,2′:1,6]pyrido[3,4b]indole derivatives |
| 06/23/2005 | WO2005056549A1 Water-soluble etoposide analogs and methods of use thereof |
| 06/23/2005 | US20050137399 A lithium-free reaction to produce a substituted/unsubstituted 4-amino-3-benzimidazol-2-yl-quinolin-2-one compound by reacting a 2-aminobenzonitrile with a 2-alkyloxycarbonylmethyl-benzimidazole in a solvent in the presence of a sodium or potassium salt of a base; excellent yields |
| 06/23/2005 | US20050137398 E. g., 3-[(4-phenoxyphenyl)thio]quinuclidine, 3-[(5-phenoxypyridin-2-yl)oxy]quinuclidine, N-(4-(1-azabicyclo[2.2.2]oct-3-yloxy)- phenyl] -N,N-bis(1-benzothien-3-yl)amine, et al: selectively modulating alpha 7-nicotinic acetylcholine; cognitive, neurodegenerative and atypical antipsychotic disorders |
| 06/23/2005 | US20050137226 3-Quinuclidinyl heteroatom bridged biaryl derivatives |
| 06/23/2005 | US20050137224 2-Cyanopyrrolidinecarboxamide compound |
| 06/23/2005 | US20050137217 Spirocyclic quinuclidinic ether derivatives |
| 06/23/2005 | US20050137204 Fused bicycloheterocycle substituted quinuclidine derivatives |
| 06/23/2005 | US20050137203 Conditions useful for treatment of cognition activators, neurodegeneration or schizophrenia |
| 06/23/2005 | US20050137196 Medical devices employing triazine compounds and compositions thereof |
| 06/23/2005 | US20050137184 Fused bicycloheterocycle substituted quinuclidine derivatives |
| 06/22/2005 | EP1543000A1 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof |
| 06/22/2005 | EP1542999A1 1h-pyrazole and 1h-pyrrole-azabicyclic compounds with alfa-7 nachr activity |
| 06/22/2005 | EP1233964B1 New use and novel n-azabicyclo-amide derivatives |
| 06/16/2005 | WO2005053663A2 Norepinephrine reuptake inhibitors useful for treatment of cognitive failure |
| 06/16/2005 | US20050131051 2-3-disubstituted quinuclidiness as modulators of monoamine transporters and theraperutic and diagnostic methods based thereon |
| 06/16/2005 | US20050131003 Heterocyclic compounds |
| 06/16/2005 | US20050129610 Imaging agents and methods of imaging alpha7-nicotinic cholinergic receptor |