| Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704) |
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| 08/03/2010 | US7767193 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| 07/29/2010 | WO2010085724A1 Preparation and therapeutic applications of (2s,3r)-n-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide |
| 07/29/2010 | US20100191475 Method for identification and functional characterization of agents which modulate ion channel activity |
| 07/29/2010 | CA2749123A1 Preparation and therapeutic applications of (2s,3r)-n-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide |
| 07/28/2010 | EP2209761A1 Diphenyl substituted cycloalkanes |
| 07/22/2010 | US20100184754 Quinolinone derivatives |
| 07/20/2010 | US7759361 treating a cancer, autoimmune diseases and cardiovscular disorders comprising administering drugs such as Isobutyric acid 2-isobutyryloxymethyl-3-oxo-1-aza-bicyclo[2.2.2]oct-ylmethyl ester; antiproliferative agents |
| 07/14/2010 | EP2206712A1 "Alkaloid aminoester derivatives and medicinal composition thereof" |
| 07/14/2010 | EP2206499A1 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists |
| 07/13/2010 | US7754189 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| 07/08/2010 | US20100174081 Production process of optically active 3-quinuclidinol derivative |
| 07/08/2010 | US20100174080 Novel palonosetron salts and processes for preparation and purification thereof |
| 07/08/2010 | US20100173880 Alkaloid aminoester derivatives and medicinal composition thereof |
| 07/06/2010 | US7750023 Quinuclidine derivatives and medicinal compositions containing the same |
| 07/06/2010 | US7750022 modulators of nicotinic and/or of the monoamine receptors such as 3-(Dibenzofuran-2-yloxy)-1-azabicyclo[2.2.2]octane, useful for the treatment of nervous system disorders, neurodegenerative diseases and drug abuse and dependence |
| 07/01/2010 | WO2010072742A1 Processes and intermediates for preparing a macrocyclic protease inhibitor of hcv |
| 07/01/2010 | WO2010072338A1 Alkaloid aminoester derivatives and medicinal composition thereof |
| 07/01/2010 | WO2010072296A1 Pyridazinone derivatives |
| 07/01/2010 | US20100168132 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists |
| 07/01/2010 | CA2748100A1 Alkaloid aminoester derivatives and medicinal composition thereof |
| 07/01/2010 | CA2747863A1 Pyridazinone derivatives |
| 07/01/2010 | CA2745565A1 Processes and intermediates for preparing a macrocyclic protease inhibitor of hcv |
| 06/30/2010 | EP1278735B1 2,4-di(hetero-)arylamino(-oxy)-5-substituted pyrimidines as antineoplastic agents |
| 06/29/2010 | US7745638 Anticancer agents; such as 4-acetylamino-1H-pyrazole-3-carboxylic acid (4-fluoro-phenyl)-amide |
| 06/29/2010 | US7745628 Method for obtaining a pharmaceutically active compound, synthesis intermediates thereof and methods for obtaining them |
| 06/24/2010 | US20100158818 Antimicrobial n-chlorinated compositions |
| 06/23/2010 | CN1934109B Composition for solid pharmaceutical preparation of solifenacin or salt thereof |
| 06/23/2010 | CN1918157B Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| 06/22/2010 | US7741489 Reacting 3-quinuclidinol with 1,3-carbonyldi(1,2,4triazole) in solvent; then 1,2,3,4-tetrahydroisoqionoline; isolation; purification |
| 06/22/2010 | CA2398988C Anti acid-fast bacterial agent containing pyridonecarboxylic acids as active ingredient |
| 06/17/2010 | US20100152233 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| 06/17/2010 | US20100152232 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| 06/16/2010 | CN101735213A Optical isomer of penehyclidine and medicinal composition and application thereof |
| 06/15/2010 | US7737285 [3-(4-{2-butyl-1-[4-(4chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl-amine, used as modulators of the interaction between the receptor for advanced glycated end products and its ligands; inflammation, nephropathy, atherosclerosis, retinopathy, Alzheimer's disease, erectile dysfunction |
| 06/15/2010 | US7737280 Reacting 1-naphthalenecarboxide with 1-azabicyclo(2.2.2)ocy-3-ylamine; atalytic hydrogenation |
| 06/10/2010 | US20100145055 Method for the preparation of solifenacin |
| 06/09/2010 | EP2194054A1 Ligands for G-protein coupled receptors |
| 06/09/2010 | EP2194053A1 Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| 06/08/2010 | US7732477 2-heteroarylcarboxylic acid amides |
| 06/03/2010 | US20100137358 Solifenacin compositions |
| 06/03/2010 | US20100137352 Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders |
| 06/03/2010 | US20100137288 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof |
| 06/02/2010 | EP1790643B1 Quinuclidine compounds having quaternary ammonium group, it's preparation method and use as blocking agents of acetycholine |
| 06/01/2010 | US7728010 Substituted benz-azoles and methods of their use as inhibitors of Raf kinase |
| 06/01/2010 | US7727997 N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives |
| 05/26/2010 | CN1642580B Radiolabelled quinoline and quinolinone derivatives and their use as metabotropic glutamate receptor ligands |
| 05/25/2010 | US7723356 Quinuclidine derivatives and their use as muscarinic m3 receptor antagonists |
| 05/25/2010 | CA2433128C Novel quinuclidine derivatives and medicinal compositions containing the same |
| 05/20/2010 | WO2010056656A2 Preparation of crystalline palonosetron hydrochloride |
| 05/19/2010 | EP2186812A1 Production process of optically active 3-quinuclidinol derivative |
| 05/19/2010 | CN101711248A An improved process for the synthesis of solifenacin |
| 05/18/2010 | US7718670 antagonists of M3 muscarinic receptors; N-(1-Azabicyclo[2.2.2]oct-3-yl)-2-hydroxy-2,2-dithien-2-ylacetamide; respiratory disorders, urological disorders, gastrointestinal disorders, cardiovascular disorders; reaction with organometallic derivative |
| 05/14/2010 | WO2010053182A1 Kynurenine production inhibitor |
| 05/12/2010 | EP1519933B1 Quinuclidine amide derivatives |
| 05/11/2010 | US7714013 Azole derivatives and fused bicyclic azole derivatives as therapeutic agents |
| 05/06/2010 | WO2010002675A3 Quinine sulfate/bisulfate solid complex; methods of making; and methods of use thereof |
| 05/06/2010 | WO2009132832A3 Method for the production of 1,4-benzothiepin-1,1-dioxide derivatives |
| 05/06/2010 | US20100113510 Quinuclidinol derivatives as muscarinic receptor antagonists |
| 05/06/2010 | US20100113509 Modulators of cystic fibrosis transmembrane conductance regulator |
| 05/06/2010 | US20100113508 Modulators of Cystic Fibrosis Transmembrane Conductance Regulator |
| 05/05/2010 | EP2181995A2 Salts and crystalline form of mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-yl-sufanyl)-acetate |
| 05/05/2010 | CN1764661B Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain. |
| 05/05/2010 | CN101018786B Process for preparing quinuclidinium carbamate derivatives |
| 05/04/2010 | US7709642 Spirohydantoin compounds and methods for the modulation of chemokine receptor activity |
| 05/04/2010 | CA2453609C Bridged piperidine derivatives as melanocortin receptor agonists |
| 04/29/2010 | WO2010048526A2 Modulators of cystic fibrosis transmembrane conductance regulator |
| 04/29/2010 | US20100105897 Novel quinuclidine derivative useful in the preparation of mequitazine |
| 04/29/2010 | US20100105724 Crystalline and amorphous forms of palonosetron hydrochloride |
| 04/29/2010 | US20100105683 Compounds useful for inhibiting chk1 |
| 04/29/2010 | US20100105677 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof |
| 04/29/2010 | US20100105658 Aza-bridged-ring compound |
| 04/28/2010 | CN1751041B 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| 04/27/2010 | US7705152 Azabicyclo[3.3.1]nonane N-oxyl having an N-oxyl group incorporated; pharmaceuticals, perfume and liquid crystal; low environmental burden, can be supplied in a large amount at a low cost |
| 04/27/2010 | US7705026 Biaryl heterocyclic compounds and methods of making and using the same |
| 04/22/2010 | WO2010043515A1 Diazonium-free method to make an indazole intermediate in the synthesis of bicyclic 5-(trifluormethoxy)-1h-3-indazolecarboxylic acid amides |
| 04/22/2010 | US20100099701 Isoquinolinone modulators of 5-ht3 receptors |
| 04/22/2010 | CA2740311A1 Diazonium-free method to make an indazole intermediate in the synthesis of bicyclic 5-(trifluormethoxy)-1h-3-indazolecarboxylic acid amides |
| 04/21/2010 | EP2176250A1 Substituted heteroarylpiperidine derivatives as melanocortin-4 receptor modulators |
| 04/15/2010 | US20100093746 3-(heteroaryl-oxy)-2-alkyl-1-aza-bicycloalkyl derivatives as alpha. 7-nachr ligands for the treatment of cns diseases |
| 04/14/2010 | EP1704146B1 Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| 04/13/2010 | USRE41226 Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase |
| 04/13/2010 | US7696242 inhibitors of the hepatitis C virus NS3 protease; azalactone intermediate reacted with cycloalkylsulfonamide and decylization; urea or carbamate-terminated alkylglycine, hydroxyproline, cyclopropylglycine tripeptide |
| 04/13/2010 | US7696222 Indole derivatives as CRTH2 receptor antagonists |
| 04/08/2010 | US20100085683 Electrolyte, electrolytic solution, and electrochemical device using the same |
| 04/07/2010 | CN1934090B Substituted N-cyclohexyl imidazolinones having an MCH-modulatory effect |
| 04/01/2010 | WO2010037129A1 Quinazolinone, quinolone and related analogs as sirtuin modulators |
| 04/01/2010 | CA2738809A1 Quinazolinone, quinolone and related analogs as sirtuin modulators |
| 03/31/2010 | CN101684118A Use of tricyclic compounds as glycine transport inhibitors |
| 03/30/2010 | US7687644 Adamantyl pyrrolidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| 03/30/2010 | US7687630 Method for producing optically active quinuclidinols having one or more substituted groups at the 2-position |
| 03/30/2010 | US7687525 e.g. N-(2-aminophenyl)-4-(N-benzoylaminomethyl)benzamide hydrochloride; anticarcinogenic, antitumor agents; hematologic malignancy and a solid carcinoma; autoimmune disease, skin disorders; |
| 03/25/2010 | US20100075967 Pyrimidine derivatives for treatment of hyperproliferative disorders |
| 03/24/2010 | EP2164843A1 Pyridazinone derivates |
| 03/24/2010 | CN101679303A pyridazinone derivatives |
| 03/23/2010 | US7683075 isoquinoline-3-carboxylic acid{(S)-1-azabicyclo[2.2.2]oct-3-yl}-amide; alpha 7 nicotinic acetylcholine receptor agonists; psychotic disorders such as schizophrenia, mania, depression and anxiety; neurodegenerative disorders such as senile dementia, Alzheimer's disease; attention deficit disorders |
| 03/18/2010 | WO2010030592A1 Compounds for the treatment of hepatitis c |
| 03/18/2010 | WO2010029313A1 Antiinfective compounds |
| 03/18/2010 | CA2736988A1 Compounds for the treatment of hepatitis c |
| 03/17/2010 | EP1786810B1 Ligands for g-protein coupled receptors |
| 03/16/2010 | US7678804 Pyrimidine derivatives for treatment of hyperproliferative disorders |