| Patents for C07D 451 - Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof (5,273) |
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| 03/31/2009 | CA2366256C Tropane analogs and methods for inhibition of monoamine transport |
| 03/26/2009 | WO2009038021A1 4-sulfonylpiperidine derivatives |
| 03/26/2009 | WO2009037719A1 Novel compounds as dipeptidyl peptidase iv (dpp iv) inhibitors |
| 03/26/2009 | WO2009037111A2 Method for the production of 1,3-dioxolane-2-ones and carboxylic acid esters by means of transacylation in basic reaction conditions |
| 03/26/2009 | CA2699909A1 Process for preparing 1,3-dioxolan-2-ones as well as carboxylic acid esters by transacylation under basic reaction conditions |
| 03/26/2009 | CA2699275A1 4-sulfonylpiperidine derivative |
| 03/25/2009 | CN101395154A 8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists |
| 03/24/2009 | US7507747 Muscarinic acetylcholine receptor antagonists |
| 03/24/2009 | US7507745 Pharmaceutical compositions based on fluorenecarboxylic acid esters and soluble TNF receptor fusion proteins |
| 03/24/2009 | US7507736 Indol-2-yl-piperazin-1-yl-methanone derivatives |
| 03/19/2009 | WO2009036243A1 Novel combination of therapeutic agents |
| 03/19/2009 | US20090076071 Deuterium-enriched retapamulin |
| 03/18/2009 | EP2036898A2 Method for manufacturing 1.3 dioxolane 2ones and carboxylic acid esters by transacylation under alkaline reaction conditions |
| 03/17/2009 | US7504512 BCL-X1 protein inhibitors; anticarcinogenic agents |
| 03/17/2009 | US7504432 Quaternary salt of (3-((2-(3,3-difluorocyclopentyl)-2-hydroxy-2-(4-methylphenyl)ethanoyl)oxy)-1,1-dimethylpyrrolidinium bromide; respiratory system disorders; chronic obstructive pulmonary diseases, bronchitis, asthma, emphysema, rhinitis; side effect reduction; inhalants; muscarinic receptor antagonists |
| 03/17/2009 | US7504426 Antiallergens; rhitinis; antiinflammatory agents |
| 03/12/2009 | US20090069432 Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's disease |
| 03/11/2009 | CN101384588A Process for preparing intermediates to 5-ht4 receptor agonist compounds |
| 03/11/2009 | CN101384555A Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments |
| 03/10/2009 | US7501436 To treat irritable bowel syndrome; side effect reduction, improved pharmacodynamics and safety, more potent and selective; 2-imidazomethyl- pyrido(4,3-b)indol-1-one or -carbazol-1-one derivatives containing an ester group |
| 03/05/2009 | WO2009029257A1 Disubstituted alkyl-8-azabicyclo [3.2.1.] octane compounds as mu opioid receptor antagonists |
| 03/05/2009 | WO2009029256A1 8-azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds as mu opioid receptor antagonists |
| 03/05/2009 | WO2009029253A1 Heteroarylalkyl-8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists |
| 03/05/2009 | WO2009029252A1 Amidoalkyl-8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists |
| 03/05/2009 | WO2009027820A2 Substituted-quinoxaline-type-piperidine compounds and the uses thereof |
| 03/05/2009 | US20090062333 8-azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds as mu opioid receptor antagonists |
| 03/05/2009 | US20090062332 Disubstituted alkyl-8-azabicyclo[3.2.1] octane compounds as mu opioid receptor antagonists |
| 03/05/2009 | US20090062331 Deuterium-enriched maraviroc |
| 03/05/2009 | CA2695755A1 8-azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds as mu opioid receptor antagonists |
| 03/04/2009 | EP1452527B1 Azabicyclo compound, matrix metalloprotease inhibitor, and skin preparation |
| 03/04/2009 | CN101379033A Secondary amines |
| 03/04/2009 | CA2697051A1 Substituted-quinoxaline-type piperidine compounds and the uses thereof |
| 02/26/2009 | WO2009026326A1 Naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine analogs and their use as agonists of the wnt-beta-catenin cellular messaging system |
| 02/26/2009 | WO2009026319A1 Naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine analogs and their use as agonists of the wnt-beta-catenin cellular messaging system |
| 02/26/2009 | US20090053172 Heterocyclic compounds as ccr5 antagonists |
| 02/26/2009 | CA2697100A1 Naphthylpyrimidine, naphthylpyrazine and naphthylpyridazine analogs and their use as agonists of the wnt-beta-catenin cellular messaging system |
| 02/25/2009 | EP1641801B9 Bridged n-arylsulfonylpiperidines as gamma-secretase inhibitors |
| 02/24/2009 | US7495010 Muscarinic acetylcholine receptor antagonists |
| 02/19/2009 | WO2009023180A1 SUBSTITUTED BICYCLIC PIPERIDINYL-AND PIPERAZINYL- SULFONAMIDES USEFUL TO INHIBIT 11β-HYDROXYSTEROID DEHYDROGENASE TYPE-1 |
| 02/19/2009 | US20090048284 Therapeutic compounds |
| 02/19/2009 | CA2696285A1 Substituted bicyclic piperidinyl- and piperazinyl-sulfonamides useful to inhibit 11.beta.-hydroxysteroid dehydrogenase type-1 |
| 02/10/2009 | US7488737 Each compound having an azabicyclic ring attached via a ring N or amino group; neuroprotectants; neurodegenerative diseases, analgesics, psychological disorders; e.g. 5-Methoxy-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxamide; ligands for nicotinic acetylcholine receptors |
| 02/05/2009 | WO2008132128A3 Synthesis of a pharmaceutically active compound |
| 02/05/2009 | WO2008125691A3 Ethers of naphtalene carboxylic acid amides as cancer cure |
| 02/05/2009 | US20090036673 Ecteinascidin 743; 5-(1,2-diaminoethyl-), 3,4-methylenedioxyphenol intermediate, of which the amine group cyclizes |
| 02/04/2009 | CN101360744A Pure and stable tiotropium bromide |
| 02/03/2009 | US7485727 4-Phenoxy-, 4-phenylthio-, 4-phenylsulfonyl- or 5-phenylsulfinyl-1-(2-pyridinyl)piperidine derivatives; insecticides, miticides and nematocides |
| 01/29/2009 | US20090030035 exo-3-(3 ,4-Dichloro-phcnoxy)-8-aza-bicyclo[3.2.1]oct-6-ene; antidepressants, psychological disorders |
| 01/29/2009 | CA2690606A1 Process for preparing an intermediate to mu opioid receptor antagonists |
| 01/28/2009 | EP2018380A2 Cns active fused bicycloheterocycle substituted azabicyclic alkane derivatives |
| 01/28/2009 | EP2018379A2 Scopine salts and their use in processes for the preparation of n-demethyl-tiotropium and tiotropium bromide |
| 01/27/2009 | US7482462 Immunosuppressants for treating skin disorders, acne, alopecia, estrogen- or androgen-dependent tumors, rheumatoid arthritis, type I and II diabetes, lupus erythematosus, multiple sclerosis, ulcerative colitis, Crohn's disease, psoriasis, contact dermatitis, graft versus host disease, eczema, asthma |
| 01/27/2009 | CA2360248C Combinations of formoterol and a tiotropium salt |
| 01/22/2009 | WO2008083367A4 Polycyclic heteroaryl substituted triazoles useful as axl inhibitors |
| 01/22/2009 | US20090023710 Compound |
| 01/21/2009 | CN101351465A 3 -monosubstituted tropane derivatives as nociceptin receptor ligands |
| 01/21/2009 | CN101351464A 8-[bis-(2-chloro-phenyl)-methyl]-3-phenyl-8-aza-bicyclo [3.2.1] octane-3-carboxylic acid amide as ligand for the nociceptin receptor ORL-1 |
| 01/20/2009 | US7479494 3-monosubstituted tropane derivatives as nociceptin receptor ligands |
| 01/20/2009 | CA2465871C Heteroaryl derivatives as superior ligands for nociceptin receptor orl-1 |
| 01/15/2009 | WO2009007115A1 Tropane derivatives useful as pesticides |
| 01/15/2009 | US20090018160 Heterocyclic Compounds with Affinity to Muscarinic Receptors |
| 01/14/2009 | EP1646365B1 Powdery formulations for inhalation, containing a novel anticholinergic agent |
| 01/13/2009 | US7476740 Monoamine transporter inhibitors; used for early diagnosis and treatment of neurological and psychiatric conditions |
| 01/13/2009 | CA2237273C Angiogenesis inhibiting pyridazinamines |
| 01/07/2009 | EP1735304B1 Quinolinone-carboxamide compounds as 5-ht4 receptor agonists |
| 01/07/2009 | CN101341137A Pyrazine derivatives as epithelial sodium channel blocker |
| 01/01/2009 | US20090005564 Methods for n-demethylation of morphine and tropane alkaloids |
| 12/31/2008 | EP2009006A1 Ureide derivative and use thereof for medical purposes |
| 12/31/2008 | EP2007725A2 Non-peptidic renin inhibitors nitroderivatives |
| 12/31/2008 | EP1737863B1 2-cyanopyrrolidinecarboxamides as dipeptidyl peptidase-iv inhibitors |
| 12/31/2008 | EP1727812B1 Novel cycloalkyl-containing 5-acylindolinones, their preparation and their use as pharmaceutical products |
| 12/25/2008 | US20080319003 Cyclic amine compound and pest control agent |
| 12/24/2008 | CN101331128A Novel forms of tiotropium bromide and processes for preparation thereof |
| 12/18/2008 | WO2008151677A1 Polymorphic form of granisetron base, methods for obtaining it and formulation containing it |
| 12/18/2008 | WO2008089201A3 Heterocyclic-substituted piperidine as orl-1 ligands |
| 12/17/2008 | EP2001876A2 8-azabicycloý3.2.1¨octane compounds as mu opioid receptor antagonists |
| 12/17/2008 | EP1773829B1 Amino-tropane derivatives, preparation thereof and therapeutic use thereof |
| 12/17/2008 | EP1673083A4 N-substituted azacycles |
| 12/17/2008 | CN100443484C Method for producing n-substituted 3beta-aminonortropanes |
| 12/16/2008 | CA2285817C Novel basic derivatives of benz[e]isoindol-1-ones and pyrrolo[3,4-c] quinolin-1-ones with 5-ht3-antagonistic activity, their preparation and their therapeutic use |
| 12/11/2008 | WO2008024892A3 Cyclic 11-beta hydroxysteroid dehydrogenase type i inhibitors |
| 12/09/2008 | US7462628 Preventives/remedies for urinary disturbance |
| 12/04/2008 | WO2008145504A2 Method for producing scopine esters |
| 12/04/2008 | CA2686872A1 Method for producing scopine esters |
| 12/03/2008 | EP1997819A1 Method for manufacturing scopinium esters |
| 12/03/2008 | EP1996584A2 Tropane prodrugs with central nervous system activity |
| 12/03/2008 | EP1028961B3 Pleuromutilin derivatives as antimicrobials |
| 12/02/2008 | US7459556 Process for preparing substituted 8-azabicyclo[3.2.1]octan-3-ols |
| 12/02/2008 | US7459464 Triple monoamine reuptake inhibitors for the treatment of chronic pain |
| 11/27/2008 | WO2008143343A1 Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position |
| 11/27/2008 | WO2008083367A3 Polycyclic heteroaryl substituted triazoles useful as axl inhibitors |
| 11/27/2008 | US20080292563 Inhalable Powder Containing Tiotropium |
| 11/27/2008 | CA2688008A1 Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position |
| 11/26/2008 | CN101312967A Carbamate compounds as 5-ht4 receptor agonists |
| 11/20/2008 | WO2008138854A1 Novel chromen-2-one derivatives |
| 11/20/2008 | CA2686891A1 Novel chromen-2-one derivatives |
| 11/19/2008 | EP1931661B1 Isoxazolo derivatives as gaba a alpha5 inverse agonists |
| 11/19/2008 | CN101309920A Novel method for producing tiotropium salts |
| 11/19/2008 | CN101307051A Process for synthesizing and detecting scopolamine derivates |
| 11/18/2008 | US7452997 Tetrahydro-indazole cannabinoid modulators |