| Patents for C07D 451 - Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof (5,273) |
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| 03/03/2015 | US8969584 PIM kinase inhibitors and preparation methods and use in medicinal manufacture thereof |
| 03/03/2015 | US8969402 Combined acetylcholinesterase inhibitor and quaternary ammonium antimuscarinic therapy to alter progression of cognitive diseases |
| 02/24/2015 | US8962841 Methods for one-pot N-demethylation/N-functionalization of morphine and tropane alkaloids |
| 02/24/2015 | US8962653 Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
| 02/24/2015 | US8962619 Substituted imidazopyridinyl-aminopyridine compounds |
| 02/17/2015 | US8957081 Compounds and compositions as protein kinase inhibitors |
| 02/12/2015 | US20150045548 Method for preparing fluorine-18 eluent with adjusted ph, and method for labelling fluorine-18 using same |
| 02/11/2015 | CN104341414A 一种抗胆碱药硫酸阿托品的制备方法 A method of preparing an anti-cholinergic drugs atropine sulfate |
| 02/11/2015 | CN104341413A 一种无水噻托溴铵的新晶型 An anhydrous tiotropium new polymorph |
| 02/11/2015 | CN104341412A 一种无水噻托溴铵结晶的制备方法 A method of preparing anhydrous crystalline tiotropium |
| 02/10/2015 | US8952169 N-substituted benzamides and methods of use thereof |
| 02/10/2015 | US8952166 Inhibitors of the renal outer medullary potassium channel |
| 02/05/2015 | US20150038718 Labeled iodinated tropane formulation |
| 02/04/2015 | EP2831069A1 ISOXAZOLE beta-LACTAMASE INHIBITORS |
| 02/04/2015 | EP2831068A1 A method of preparing the scopine ester of di-(2-thienyl)glycolic acid, an intermediate in the synthesis of tiotropium bromide |
| 02/04/2015 | CN104334555A 异噁唑β-内酰胺酶抑制剂 Isoxazole β- lactamase inhibitor |
| 02/04/2015 | CN102325752B 咔唑和咔啉激酶抑制剂 Carbazole and carboline kinase inhibitor |
| 02/03/2015 | USRE45364 Cyclic amine compound and pest control agent |
| 01/29/2015 | US20150031887 9-azanoradamantane n-oxyl compound and method for producing same, and organic oxidation catalyst and method for oxidizing alcohols using 9-azanoradamantane n-oxyl compound |
| 01/28/2015 | CN104311550A 一种6-羟基托品酮的制备方法 One kind of preparation 6- hydroxy ketone product Underpinning |
| 01/27/2015 | US8940762 Methods for treating pain |
| 01/22/2015 | US20150025057 Triazine-oxadiazoles |
| 01/22/2015 | US20150025054 (hetero)aryl cyclopropylamine compounds as lsd1 inhibitors |
| 01/21/2015 | EP2825535A1 A method of preparing the scopine ester of di-(2-thienyl)glycolic acid, an intermediate in the synthesis of tiotropium bromide, and its new form |
| 01/15/2015 | US20150018556 Process for Preparing Tiotropium Bromide |
| 01/14/2015 | CN104277081A 一种羟基肉桂酸胺类化合物及其制备和应用 One hydroxy acid amine compounds and their preparation and use |
| 01/14/2015 | CN102887893B 一种托烷司琼的制备方法 Preparation of an alkyl granisetron Tropsch |
| 01/13/2015 | US8933236 N-substituted benzamides and methods of use thereof |
| 01/13/2015 | US8933229 8-azabicyclo[3.2.1]octane-8-carboxamide derivative |
| 01/13/2015 | US8933103 Pyridone derivatives |
| 01/08/2015 | US20150011752 Triazine compounds as pi3 kinase and mtor inhibitors |
| 01/08/2015 | US20150011534 Pyridazinone derivatives |
| 01/06/2015 | US8927540 Pyridazinone derivatives |
| 01/06/2015 | US8927531 Indanyloxydihydrobenzofuranylacetic acids |
| 01/06/2015 | US8927503 Modulations of protease activated receptors |
| 12/31/2014 | CN102964344B 噻托铵盐、其医药制剂及其用途 Tiotropium salts, the pharmaceutical preparations and their use |
| 12/30/2014 | US8921544 Oxazole tyrosine kinase inhibitors |
| 12/30/2014 | US8921357 Pyridazinone derivatives |
| 12/24/2014 | CN104230935A 含有脂环结构化合物的抗肿瘤作用与应用 Anti-tumor effect and application of compounds containing alicyclic structure |
| 12/24/2014 | CN104230919A 一种从曼陀罗花中提取莨菪碱的方法 A method to extract from Datura flowers of scopolamine |
| 12/23/2014 | US8916593 Alkoxy-substituted 2-aminopyridines as ALK inhibitors |
| 12/11/2014 | US20140364451 Tropinol esters and related compounds to promote normal processing of app |
| 12/09/2014 | US8907095 Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 |
| 12/09/2014 | US8906911 Chemokine receptor antagonists |
| 11/25/2014 | US8895733 Triazine-oxadiazoles |
| 11/25/2014 | US8895554 Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as Alzheimer's disease, type 2 diabetes, and Parkinson's disease |
| 11/13/2014 | US20140336374 Process and intermediates for the production of ccr2 antagonists |
| 11/13/2014 | US20140336198 Amine Derivatives as Potassium Channel Blockers |
| 11/13/2014 | US20140336137 Novel nitroso compounds as nitroxyl donors and methods of use thereof |
| 11/04/2014 | US8877743 Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors |
| 10/30/2014 | US20140323732 New process for the production of tiotropium salts |
| 10/30/2014 | US20140323515 Novel Forms Of Tiotropium Bromide And Processes For Preparation Thereof |
| 10/23/2014 | US20140316138 Process for preparing new tiotropium salts, new tiotropium salts as such and pharmaceutical compositions thereof |
| 10/23/2014 | US20140315884 Ampk-activating heterocyclic compounds and methods for using the same |
| 10/21/2014 | US8865903 Continuous process for the alkylation of cyclic tertiary amines |
| 10/14/2014 | US8859580 Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| 10/14/2014 | US8859559 Substituted pyrazines and their use in the treatment of disease |
| 10/14/2014 | US8859535 Hydroxy substituted isoquinolinone derivatives |
| 10/09/2014 | WO2014164682A1 Azaadamantane formate ester and process preparing azaadamantane derivatives |
| 10/09/2014 | US20140303143 Benzoxazolinone compounds with selective activity in voltage-gated sodium channels |
| 10/07/2014 | US8853241 Biaryl substituted azabicyclic alkane derivatives |
| 10/02/2014 | WO2014154488A1 Methods of controlling neonicotinoid resistant pests |
| 10/02/2014 | WO2014154487A1 Methods of controlling neonicotinoid resistant pests |
| 10/02/2014 | WO2014154486A1 Methods of controlling neonicotinoid resistant pests |
| 09/30/2014 | US8846926 Forms of tiotropium bromide and processes for preparation thereof |
| 09/30/2014 | US8846655 4-substituted-2-phenoxy-phenylamine delta opioid receptor modulators |
| 09/25/2014 | WO2014152144A1 Muscarinic agonists |
| 09/25/2014 | US20140288112 8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists |
| 09/25/2014 | US20140288051 Bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors |
| 09/23/2014 | CA2616222C Method for producing tiotropium salts comprising an esterification reaction of methylscopinium and a dithienyl derivative |
| 09/18/2014 | WO2014140318A1 Improved process for acyl transfer reactions |
| 09/18/2014 | US20140275057 Novel compounds and compositions for the inhibition of nampt |
| 09/16/2014 | US8835682 Alkaloid aminoester derivatives and medicinal composition thereof |
| 09/16/2014 | US8835457 Bridged bicyclic RHO kinase inhibitor compounds, compositions and use |
| 09/16/2014 | US8835456 NS5A inhibitors useful for treating HCV |
| 09/16/2014 | US8835440 Cyclic pyrimidin-4-carboxamides as CCR2 receptor antagonists for treatment of inflammation, asthma and COPD |
| 09/11/2014 | US20140256769 Crystalline form of a quinolinone-carboxamide compound |
| 09/09/2014 | US8829027 Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use |
| 09/09/2014 | CA2591766C Tetrahydroquinoline analogues as muscarinic agonists |
| 08/28/2014 | WO2014128486A1 Pyrimidine compounds useful in the treatment of diseases mediated by ikke and/or tbk1 mechanisms |
| 08/28/2014 | US20140243290 Aminopyrimidines as SYK Inhibitors |
| 08/26/2014 | US8816091 Crystalline forms of an 8-azabicyclo[3.2.1]octane compound |
| 08/21/2014 | US20140235669 Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 08/21/2014 | DE50103551C5 Neue tiotropium-haltige inhalationspulver New tiotropium-containing inhalation powder |
| 08/20/2014 | EP2766352A1 Indazole compounds as kinase inhibitors and method of treating cancer with same |
| 08/19/2014 | US8809381 Highly selective sigma receptor ligands |
| 08/14/2014 | WO2014122067A1 New indanyloxydihydrobenzofuranylacetic acids |
| 08/14/2014 | WO2014097151A3 Autotaxin inhibitors |
| 08/14/2014 | US20140228353 Compounds and methods of treating diabetes |
| 08/13/2014 | CN103987707A 吡唑-4-基-杂环基-甲酰胺化合物以及使用方法 Pyrazol-4-yl - heterocyclyl - carboxamide compound, and use of |
| 08/12/2014 | US8802698 8-azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds as mu opioid receptor antagonists |
| 08/07/2014 | US20140221420 Ccr5 antagonists for treating hiv |
| 08/07/2014 | US20140221341 Bicyclic compounds and their use as antibacterial agents and betalactamase inhibitors |
| 08/06/2014 | EP2760857A1 Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use |
| 08/06/2014 | CN101910152B 作为janus激酶抑制剂的4-吡唑基-n-芳基嘧啶-2-胺和4-吡唑基-n-杂芳基嘧啶-2-胺 As janus kinase inhibitors 4- pyrazolyl -n- aryl-pyrimidin-2-amine and 4-pyrazolyl -n- heteroaryl pyrimidin-2-amine |
| 07/30/2014 | CN103951665A 新型托品醇类氨基酸阴离子型手性离子液体的制备、固定化及其拆分dl-苯丙氨酸和dl-色氨酸的方法 Preparation of anionic amino alcohols, chiral ionic liquids new care products, immobilization and split dl- phenylalanine and tryptophan method dl- |
| 07/30/2014 | CN101910168B 托烷化合物 Tropane compound |
| 07/24/2014 | US20140206718 Method of enhancing lysosomal alpha-Galactosidase A |
| 07/24/2014 | US20140206660 Phenyl-Heteroaryl Derivatives and Methods of Use Thereof |
| 07/16/2014 | EP2754660A1 Pyridazinon derivatives |