| Patents for C07D 451 - Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof (5,273) |
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| 06/05/2013 | CN101979391B Method for preparing tiotropium bromide |
| 06/05/2013 | CN101798257B Automatic synthesis method of methylation reagent [11C] CH3Br |
| 05/29/2013 | CN101768158B Tiotropium bromide anhydride and preparation method thereof |
| 05/29/2013 | CN101407514B Tiotropium salts, tiotropium salts pharmaceutical formulations and uses thereof |
| 05/29/2013 | CN101331128B Novel forms of tiotropium bromide and processes for preparation thereof |
| 05/28/2013 | CA2530886C Dual nk1/nk3 antagonists for treating schizophrenia |
| 05/22/2013 | CN103119028A 1,2,4-Triazolone Derivative |
| 05/16/2013 | US20130123268 3,3-disubstituted-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanones as inhibitors of 11 (beta)-hsd1 |
| 05/16/2013 | US20130123243 Diamine derivatives as inhibitors of leukotriene a4 hydrolase |
| 05/10/2013 | WO2013064919A1 Quinazoline derivatives with hsp90 inhibitory activity |
| 05/09/2013 | US20130116435 New process for the production of tiotropium salts |
| 05/08/2013 | CN101511818B N-pyridylpiperidine compound, method for producing the same, and pest control agent |
| 05/02/2013 | WO2013062027A1 Azole derivative |
| 05/02/2013 | WO2013061977A1 Heterocycle derivative having pgd2 receptor antagonist activity |
| 05/02/2013 | CA2853227A1 Azole derivative |
| 05/02/2013 | CA2852627A1 Heterocyclic derivative having pgd2 receptor antagonist activity |
| 05/01/2013 | EP2585456A1 Amido-tropane derivatives |
| 05/01/2013 | CN103073543A Preparation method and application of tropisetron citrate crystal form I |
| 05/01/2013 | CN103073542A Preparation method and application of tropisetron citrate crystal form II |
| 05/01/2013 | CN102351856B Purification method of alpha-tropine |
| 04/30/2013 | US8431702 Therapeutically useful substituted hydropyrido [3,2,1-ij] quinoline compounds |
| 04/24/2013 | CN102183589B Method for detecting contents of dolasetron isomer and salt thereof |
| 04/18/2013 | WO2013055910A1 Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| 04/18/2013 | WO2013053051A1 Indazole compounds as kinase inhibitors and method of treating cancer with same |
| 04/18/2013 | CA2850394A1 Indazole compounds as kinase inhibitors and method of treating cancer with same |
| 04/17/2013 | CN102070630B New tiotropium salts, pharmaceutical compositions containing the same and use thereof |
| 04/16/2013 | US8420630 Pyrimidine derivatives |
| 04/11/2013 | WO2013050929A1 Manufacturing process for tiotropium bromide |
| 04/10/2013 | CN101712679B Acylamide class compound, medicine composition, preparation method and application thereof |
| 04/04/2013 | WO2013046138A1 Process for the preparation of scopine esters |
| 04/04/2013 | WO2013045461A1 Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use |
| 04/04/2013 | CA2845191A1 Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use |
| 04/02/2013 | US8410094 Amide compounds, their pharmaceutical compositions, their preparation method and their uses |
| 03/28/2013 | US20130079523 Process for preparing an intermediate to mu opioid receptor antagonists |
| 03/28/2013 | US20130079514 "omega-aminoalkylamides of r-2-aryl-propionic acids as inhibitors of the chemotaxis of polymorphonucleate and mononucleate cells" |
| 03/27/2013 | CN102993197A Tropinone derivative, and preparation method and application thereof |
| 03/26/2013 | US8404708 Dual NK1/NK3 receptor antagonists |
| 03/21/2013 | US20130072515 Crystalline forms of an 8-azabicyclo[3.2.1]octane compound |
| 03/13/2013 | CN102971304A GPR119 agonist |
| 03/13/2013 | CN102964345A Method for preparing 2-hydroxy-2,2-diphenylacetic acid-3alpha-(8-aza-bicyclo(3,2,1))-3-trioctyl |
| 03/13/2013 | CN102964344A Novel tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same |
| 03/12/2013 | US8394819 Indole derivatives as CRTH2 receptor antagonists |
| 03/06/2013 | EP2563780A1 3, 3 -disubstituted- ( 8 - aza - bicyclo [3.2.1]oct- 8 - yl) -[5- (1h - pyrazol - 4 -yl) -thiophen-3 -yl]methanones as inhibitors of 11 (beta) -hsd1 |
| 02/28/2013 | US20130053364 Sulphone Compounds and Methods of Making and Using Same |
| 02/27/2013 | CN102947297A Amido-tropane derivatives |
| 02/27/2013 | CN102947295A 3,3-disubstituted-(8-aza-bicyclo [3.2.1]oct-8-y)-[5-(1 -pyrazol-4-yl)-thiophe-3-yl] methanones as inhibitors of 11[beta]-HSD1 |
| 02/27/2013 | CN101824033B Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| 02/26/2013 | US8383817 Benztropine compounds and uses thereof |
| 02/21/2013 | US20130045951 Novel Nitroso Compounds as Nitroxyl Donors and Methods of Use Thereof |
| 02/20/2013 | EP1934212B1 9-azabicyclo [3 . 3 . 1]nonane derivatives as monoamine reuptake inhibitors |
| 02/19/2013 | US8378103 Process for the preparation of tiotropium bromide |
| 02/14/2013 | US20130041106 Chemoselective enrichment for compound isolation |
| 02/14/2013 | US20130040986 Modulators of Cystic Fibrosis Transmembrane Conductance Regulator |
| 02/14/2013 | US20130040985 Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 02/13/2013 | CN102924446A PIM kinase inhibitor, preparation method thereof, and application thereof in pharmacy |
| 02/13/2013 | CN102146079B Preparation method of scopolamine butylbromide |
| 02/12/2013 | CA2480638C Substituted benzazoles and use thereof as raf kinase inhibitors |
| 02/07/2013 | WO2013018929A1 Nitrogen-containing heterocyclic compound |
| 02/07/2013 | WO2013017585A1 Precursor compounds for the radiosynthesis of [18f] norchloro-fluorohomoepibatidine |
| 02/07/2013 | DE102011052348B3 Präkursorverbindungen für die Radiosynthese von [18F]Norchlor-fluor-homoepibatidin Precursor compounds for the radio synthesis of [18F] fluoro-Norchlor-homoepibatidin |
| 02/07/2013 | CA2841800A1 Precursor compounds for the radiosynthesis of [18f] norchloro-fluorohomoepibatidine |
| 02/06/2013 | EP2552913A1 Method for synthesis of tiotropium bromide |
| 02/06/2013 | EP2552912A1 Synthesis method for producing tiotropium bromide |
| 02/06/2013 | EP2552911A1 Tiotropium bromide preparation process |
| 01/31/2013 | WO2013016160A1 NOVEL IMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS mTOR INHIBITORS |
| 01/24/2013 | WO2013012827A1 Diaminocyclohexane compounds and uses thereof |
| 01/23/2013 | EP2547203A1 Ccr5 modulators for treating hiv |
| 01/23/2013 | CN102887893A Preparation method of tropisetron |
| 01/23/2013 | CN101993443B Novel crystal form of benzilic acid nortropine easter and preparation method thereof |
| 01/22/2013 | US8357686 Aryl-substituted polycyclic amines, method for the production thereof, and use thereof as a medicament |
| 01/17/2013 | WO2012146724A3 Novel rock inhibitors |
| 01/16/2013 | CN101861315B Method for producing 2-azaadamantane |
| 01/02/2013 | EP2540719A1 Cyclic amine compound and miticide |
| 01/02/2013 | CN102850343A Pretreatment method for alkaloid in Anisodus tanguticus |
| 01/01/2013 | US8344143 Process for the preparation of tiotropium bromide |
| 12/27/2012 | WO2012175520A1 Hydroxy substituted isoquinolinone derivatives |
| 12/27/2012 | WO2012071509A3 Benzoxazepines as inhibitors of p13k/mtor and methods of their use and manufacture |
| 12/27/2012 | US20120329828 Cocaine Analogs and Methods of Preparation and Uses Thereof |
| 12/26/2012 | EP2537830A1 Compounds and compositions as protein kinase inhibitors |
| 12/20/2012 | US20120322804 N-linked heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders |
| 12/18/2012 | US8334303 Specifically mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate (SB 268091); use as antibiotic; crystallization from isopropanol; improved bioavailability, and/or physical properties, for example solubility or flow properties |
| 12/13/2012 | WO2012168359A1 Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| 12/12/2012 | EP2532656A1 Gpr119 agonist |
| 12/06/2012 | DE112010005112T5 Verfahren zur Herstellung von Nortropylbenzilat und dessen Salzen sowie dabei verwendeten Zwischenprodukten A process for preparing Nortropylbenzilat and its salts as well as intermediates used therein |
| 11/29/2012 | US20120302541 4-substituted-2-phenoxy-phenylamine delta opioid receptor modulators |
| 11/28/2012 | EP2527317A1 Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors |
| 11/28/2012 | EP2527315A1 Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as Alzheimer's disease, type 2 diabetes and Parkinson's disease |
| 11/28/2012 | CN102796095A Tetrahydroquinoline analogues as muscarinic agonists |
| 11/28/2012 | CN102060853B Method for separating alkaloid by reversely two-way eluted pH-zone-refining counter-current chromatography |
| 11/27/2012 | CA2695742C Bicyclic amides for enhancing glutamatergic synaptic responses |
| 11/22/2012 | US20120295877 Therapeutic Compounds |
| 11/21/2012 | EP2523562A1 Nicotinic acetylcholine receptor modulators |
| 11/15/2012 | WO2012152854A1 Metabotropic glutamate receptor modulators |
| 11/15/2012 | US20120289700 Cyclic amine compound and acaricide |
| 11/14/2012 | CN102781938A Preparation of N-monofluoroalkyl tropanes |
| 11/13/2012 | US8309729 Therapeutically useful substituted hydropyrido [3,2,1-ij] quinoline compounds |
| 11/08/2012 | US20120283249 Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action |
| 11/07/2012 | CN102770430A Cyclic amine compound and miticide |
| 11/07/2012 | CN102367251B More stable tropisetron compound and pharmaceutical composition thereof |
| 11/06/2012 | US8304426 Polymorphic form of Granisetron base, methods for obtaining it and formulation containing it |