| Patents for C07D 451 - Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof (5,273) |
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| 08/06/2008 | EP1951721A1 3 -monosubstituted tropane derivatives as nociceptin receptor ligands |
| 08/06/2008 | EP1951720A1 8-[bis-(2-chloro-phenyl)-methyl]-3-phenyl-8-aza-bicyclo [3.2.1]octane-3-carboxylic acid amide as ligand for the nociceptin receptor orl-1 |
| 08/06/2008 | CN101238131A Bridged piperazine and piperidine derivatives as CCR1 antagonists |
| 08/06/2008 | CN100408575C Aryl-8-azabicyclo[3,2,1]octanes for treating depression |
| 08/06/2008 | CN100408574C Nicotinic acid-heterocyclyl-amides and analogous pyrimidine derivatives serving as pesticides |
| 08/05/2008 | US7407970 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 07/31/2008 | WO2008089852A1 Novel process for preparing tiotropium salts |
| 07/31/2008 | WO2008073687A3 Compounds and compositions as protein kinase inhibitors |
| 07/30/2008 | EP1950196A1 Method for manufacturing ammonium hexafluorphosphates |
| 07/30/2008 | EP1948653A1 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 07/30/2008 | EP1948596A2 Soft anticholinergic esters |
| 07/30/2008 | CN101230063A Method for preparing tiotropium bromide |
| 07/30/2008 | CN101230062A Muscarinic acetycholine receptor antagonists |
| 07/30/2008 | CN101230061A Muscarinic acetycholine receptor antagonists |
| 07/30/2008 | CN101230034A Nitrogen hetero-cycle compounds for use in the treatment of 5-hydroxide tryptamines related diseases |
| 07/30/2008 | CN100406456C Process for preparing scopine esters |
| 07/29/2008 | US7405305 Pyrrole-2, 5dione derivatives and their used as GSK-3 inhibitors |
| 07/29/2008 | US7405224 Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions |
| 07/24/2008 | WO2008089201A2 Heterocyclic-substituted piperidine as orl-1 ligands |
| 07/24/2008 | WO2008026658A8 N-pyridylpiperidine compound, method for producing the same, and pest control agent |
| 07/24/2008 | WO2007137030A3 Cns active fused bicycloheterocycle substituted azabicyclic alkane derivatives |
| 07/24/2008 | WO2007106423A3 Tropane prodrugs with central nervous system activity |
| 07/24/2008 | US20080176895 Gastrointestinal disorders; selectivity, potency, pharmacokinetics, duration of action; minimal side effects |
| 07/24/2008 | CA2823905A1 Heterocyclic-substituted piperidine compounds and the uses thereof |
| 07/24/2008 | CA2823883A1 Heterocyclic-substituted piperidine compounds and the uses thereof |
| 07/24/2008 | CA2675419A1 Heterocyclic-substituted piperidine compounds and the uses thereof |
| 07/23/2008 | CN101228158A N-amide derivatives of 8-azabicyclo[3.2.1]oct-3-yl as ccr1 antagonists |
| 07/23/2008 | CN101227905A Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof |
| 07/22/2008 | US7402835 Heteroatom-containing diamondoid transistors |
| 07/16/2008 | EP1641801B1 Bridged n-arylsulfonylpiperidines as gamma-secretase inhibitors |
| 07/16/2008 | EP1506205B1 Novel azacyclic ethynyl derivatives |
| 07/16/2008 | EP1476151B1 1-arylsulfonyl-3-substitued indole and indoline derivates useful in the treatment of central nervous system disorders |
| 07/16/2008 | CN101220025A Micronized crystalline tiotropium bromide |
| 07/16/2008 | CN100402032C Tetrahydroquinoline analogues as muscarinic agonists |
| 07/15/2008 | CA2425560C Anticholinergics, processes for preparing them and their use as pharmaceutical compositions |
| 07/10/2008 | WO2008063600A3 Triazolyl tropane derivatives |
| 07/09/2008 | CN100400519C N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines |
| 07/03/2008 | US20080161342 Specifically mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate (SB 268091); use as antibiotic; crystallization from isopropanol; improved bioavailability, and/or physical properties, for example solubility or flow properties |
| 07/03/2008 | US20080161310 (2S)-4,4-difluoro-1-(2-{[1-(2-pyrazinyl)piperidin-4-yl]amino}acetyl)-2-pyrrolidine carbonitrile; enzyme inhibitors; diabetes |
| 07/03/2008 | US20080161264 N-{3-[3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-exo-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl}-4,4-difluorocyclohexanecarboxamide; with deuterium isotop; chemokine (C-C motif) CCR5 receptor antagonist; antiinflammatory agent, viricide; with other active ingredients; HIV, AIDS, multiple sclerosis |
| 07/03/2008 | CA2673921A1 Substituted isoquinolines and their use as rho-kinase inhibitors |
| 07/02/2008 | EP1937267A2 M3 muscarinic acetylcholine receptor antagonists |
| 07/02/2008 | EP1937261A1 Novel azabicyclo[3.2.1]oct-2-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 07/02/2008 | EP1937230A2 M3 muscarinic acetylcholine receptor antagonists |
| 07/02/2008 | CN101210014A Setron-like compounds, preparation method and medicament use thereof |
| 07/02/2008 | CN100398538C Process for preparing N-2-fluoro ethyl-2 beta-carbomethoxy-3 beta-(4-chlorphenyl) nor tropane |
| 07/02/2008 | CN100398103C Treatment of affective disorders by the combined action of a nicotinic receptor agonist and a monoaminergic substance |
| 06/26/2008 | WO2008077103A1 Preperation and utility of ccr5 inhibitors |
| 06/26/2008 | WO2008074798A1 Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 06/26/2008 | WO2008074797A1 Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 06/26/2008 | WO2008074703A1 Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives |
| 06/26/2008 | WO2008058096A9 Azaadamantane derivatives and their uses as nicotinic acetylcholine receptors ligands |
| 06/26/2008 | US20080153870 Cocaine receptor binding ligands |
| 06/26/2008 | US20080153809 Novel amides useful for treating pain |
| 06/26/2008 | CA2673566A1 Preparation and utility of ccr5 inhibitors |
| 06/26/2008 | CA2673454A1 Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 06/26/2008 | CA2673315A1 Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 06/26/2008 | CA2671378A1 Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives |
| 06/25/2008 | EP1935887A1 Heterocyclic substituted carbonyl derivatives and their use as dopamine D3 receptor ligands |
| 06/25/2008 | EP1934212A1 9-azabicyclo [3 . 3 . 1]nonane derivatives as monoamine reuptake inhibitors |
| 06/24/2008 | US7390902 N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-2-methoxy-5-iodo-benzamide; high affinity and high selectivity for sigma 2 receptors; Bromine, Iodine, Carbon, Tritium radioisitops; PET and SPECT; breast cancer |
| 06/19/2008 | US20080146807 Indazole-carboxamide compounds as 5-HT4 receptor agonists |
| 06/18/2008 | EP1932844A1 Bridged cyclic amine compound and pest control agent |
| 06/18/2008 | EP1931661A1 Isoxazolo derivatives as gaba a alpha5 inverse agonists |
| 06/18/2008 | CN101203513A Novel crystalline forms of tiotropium bromide |
| 06/17/2008 | CA2439152C Acylated piperidine derivatives as melanocortin-4 receptor agonists |
| 06/12/2008 | US20080139603 Azabicycloalkane compounds |
| 06/11/2008 | EP1930330A1 Pleuromutilin derivatives as antimicrobials |
| 06/11/2008 | CN101198606A Alpha-(aryl-or heteroaryl-methyl)-beta piperidino propanamide compounds as ORL1-receptor antagonists |
| 06/11/2008 | CN100393719C Process for preparing an anticholinergic |
| 06/05/2008 | US20080132537 Viricides; antiinflammatory agents; infection therapy; respiratory system disorders |
| 06/03/2008 | US7381733 Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases |
| 05/29/2008 | WO2008063600A2 Triazolyl tropane derivatives |
| 05/28/2008 | EP1925615A1 Method of fluorine-18 labelling of tropane derivatives |
| 05/28/2008 | EP1924551A2 Organic compounds |
| 05/28/2008 | CN101189232A 3-aryloxy-8-aza-bicyclo [3.2.1.] oct-6-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| 05/27/2008 | US7378526 Cholinergic ligands at the nicotinic acetylcholine receptors; diseases related to the cholinergic system; neurodegenerative disorders; pain; antiinflammatory; diagnostic or monitoring tools using labelled forms; 3-Phenyletynyl-quinuclidin-2-ene |
| 05/22/2008 | WO2008059349A1 Method of fluorine-18 labelling of tropane derivatives |
| 05/22/2008 | WO2008058968A1 Crystalline form of tiotropium bromide and urea |
| 05/22/2008 | CA2669395A1 Crystalline form of tiotropium bromide and urea |
| 05/21/2008 | EP1923393A1 Crystalline form of tiotropium bromide and urea |
| 05/21/2008 | CN101184753A Novel mchr1 antagonists and their use for the treatment of mchr1 mediated conditions and disorders |
| 05/21/2008 | CN100389113C Nitrogenous heterocyclic compound and medicine containing the same |
| 05/20/2008 | US7375114 minimal side effects, selectivity, potency, pharmacokinetics, duration of action; CNS disorders like cognitive, behavioral, mood, autonomic functions; 1-isopropyl-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid {(1S,3R,5R)-8-[3-acetylamino-2-hydroxypropyl]-8-azabicyclo[3.2.1]oct-3-yl}amide |
| 05/15/2008 | CA2668962A1 Azaadamantane derivatives and their uses as nicotinic acetylcholine receptors ligands |
| 05/14/2008 | EP1919476A2 Benztropine compounds and uses thereof as dopamine uptake inhibitors |
| 05/13/2008 | US7371766 Curcumin analogs with anti-tumor and anti-angiogenic properties |
| 05/07/2008 | EP1558600B1 Selected cgrp antagonists, method for production and use thereof as medicament |
| 05/06/2008 | US7368460 Tropane derivatives useful in therapy |
| 05/06/2008 | US7368457 Bridged N-arylsulfonylpiperidines as gamma-secretase inhibitors |
| 05/01/2008 | US20080103166 Administering tropisetron to prevent and treat Schizophrenia, Alzheimer's, Parkinson's, and Huntington's Diseases,Tourette's Syndrome and Attention deficit disorder; antidepressants, anxiolytic and antiepileptic agents |
| 05/01/2008 | US20080103161 Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for the preparation thereof |
| 04/30/2008 | EP1915371A2 Bridged n-bicyclic sulfonamido inhibitors of gamma secretase |
| 04/30/2008 | CN100384421C N-(substituted arylmethyl)-4-(disubstituted methyl) piperidines and pyridines |
| 04/29/2008 | US7365082 N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines |
| 04/29/2008 | US7365070 Such as N-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-fluoro-benzoyl}-N'-butyl-guanidine; involuntary weight loss disorders |
| 04/24/2008 | US20080096922 N-{[cis-1-(3-methoxyphenyl)-4-(piperidin-4-ylamino)-cyclohexyl]methyl}sulfamide diHCL; tert-butyl [({[cis-4-[(biphenyl-4-ylmethyl)amino]-1-(3-methoxyphenyl)cyclohexyl]methyl}amino)sulfonyl]carbamate; for potentiating expression of low density lipoprotein recepotr; arteriosclerosis; hyperlipidemia |
| 04/23/2008 | CN101166738A Novel crystalline forms of tiotropium bromide |
| 04/22/2008 | US7361667 Attention defect disorders; alcoholism; drug abuse; Parkinson's disease; anxiolytic agents; antidepressants |
| 04/17/2008 | WO2008019372A3 2-aminobenzoxazole carboxamides as 5ht3 modulators |