Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
05/1999
05/12/1999EP0627007B1 Process for the enzymatic oxidation of (d)-lactic acid to pyruvic acids
05/11/1999US5902736 Using decarbamylase from comamonas, alcaligenes, rhizobium, blastobacter, sporosarcina, and bradyrhyzobium species in aqueous medium; as chemical intermediates for semisynthetic penicillin and cephalosporin
05/06/1999WO1999022015A1 Method for preparing optically active 5-hydroxy-3- (4'-hydroxyphenyl)-1, 1,3-trimethylindane
05/06/1999WO1999022014A1 Process for preparing (2r,3s)-3-(4-lower alkoxyphenyl)glycidic acid esters
05/06/1999EP0912755A1 The bioresolution of n-acylazetidine-2-carboxylic acids
05/06/1999EP0912504A1 Process to prepare taxol
05/06/1999CA2316294A1 Method for preparing optically active 5-hydroxy-3- (4'-hydroxyphenyl)-1, 1,3-trimethylindane
05/05/1999CN1216039A Process to prepare taxol
05/04/1999US5900369 Adding lipase to ketoalcohol and vinyl acetate, producing optically active ester; chemical intermediate for analgesics
05/04/1999US5900368 Process for bioreduction of bisaryl ketone to bisaryl alcohol
05/04/1999US5900237 Catalytic antibodies which hydrolyze primary amides and methods for eliciting such antibodies
05/04/1999CA1340524C Process for preparing optically active 2-arylpropionic acids
04/1999
04/28/1999EP0910661A1 Production of amino acids and enzymes used therefor
04/28/1999EP0910660A1 Process for producing optically active amines
04/28/1999CN1215434A Enzymatic process stereoselective preparation of therapeutic amides
04/28/1999CN1215085A Enzyme method separation process for racemic ketoprofen
04/27/1999CA1340511C Method of catalyzing chemical reactions using monoclonal antibodies
04/21/1999EP0909821A2 Engineering enzymes having altered substrate specificity
04/21/1999EP0909757A2 Process for producing optically active pentanetetraols
04/14/1999EP0908522A1 A method for producing an optically active 2-alkanol
04/08/1999WO1999016439A1 CHRONIC, BOLUS ADMINISTRATION OF D-threo METHYLPHENIDATE
04/07/1999EP0647266B1 D-enzyme compositions and methods of their use
04/07/1999CN1213400A Process for producing N-protected D-proline derivatives
04/02/1999CA2246045A1 The alteration of the substrate specificity of enzymes
03/1999
03/31/1999EP0905257A1 Process for preparing optically active 2-amino-Omega-oxoalkanoic acid derivatives
03/31/1999EP0904400A2 Enzymatic process for stereoselective preparation of therapeutic amides
03/31/1999EP0904348A1 Process for the preparation of amino alcohols and derivatives thereof
03/30/1999US5889190 Stability; capable of systemic infections; transcription;gene expression
03/30/1999US5888785 Method for using hydratase or a hydratase-amidase fusion for stereospecifically bioconverting certain racemic nitriles to the corresponding enatiomeric R--or S-amide or s-carboxylic acid
03/25/1999CA2247952A1 Process for preparing optically active 2-amino-w-oxoalkanoic acid derivatives
03/23/1999US5885816 Catalytic antibodies enantioselectively hydrolysing amino acid ester derivatives
03/23/1999US5885787 Process for preparing optically active amines
03/16/1999US5883264 Subjecting racemic trans-3-phenylglycidamide compound to optical resolution using a microorganism having ability of preferentially hydrolyzing one of (2s,3r) isomer or (2r,3s) isomer thereof
03/09/1999US5879930 Process for the enzymatic resolution of 2-amino-4-methyl-phosphinobutyric acid derivatives
03/09/1999US5879929 Enzymatic processes for the resolution of enantiomeric mixtures of lactams useful as intermediates in the preparation of taxanes
03/09/1999US5879903 Using gene obtained from streptomyces viridochromogenes as antibiotic resistance marker in transformed bacteria
03/09/1999CA2038610C Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde
03/04/1999WO1999010519A1 Process for preparing enantiomerically enriched n-derivatised lactams
03/04/1999CA2295017A1 Process for preparing enantiomerically enriched n-derivatised lactams
02/1999
02/25/1999WO1999009200A1 Method for racemic biochemical resolution of cis- and trans- pyrrolopiperidine
02/25/1999CA2300119A1 Method for racemic biochemical resolution of cis- and trans- pyrrolopiperidine
02/24/1999CN1209171A Process for preparing intermediates for synthesis of antifungal agents
02/23/1999US5874613 3-(3-chlorophenyl) serine
02/18/1999WO1999007875A1 Process for preparing (2r,3s)-3-(substituted or unsubstituted phenyl)glycidamide compounds by asymmetric amidation
02/18/1999WO1999007873A1 METHOD FOR PRODUCING CYCLIC α-AMINO ACIDS FREE FROM ENANTIOMERS OR THEIR N-PROTECTED DERIVATIVES BY MEANS OF A D-SPECIFIC AMINOACYLASE
02/18/1999DE19735198A1 Optical resolution of cis- or trans-pyrrolo:piperidine derivatives
02/18/1999CA2299324A1 Method for producing cyclic .alpha.-amino acids free from enantiomers or their n-protected derivatives by means of a d-specific aminoacylase
02/17/1999EP0896617A1 Process for producing n-protected d-proline derivatives
02/10/1999EP0896057A2 D-aminoacylase
02/09/1999CA2121180C Norbornane type ester hydrolase
02/09/1999CA1340382C Process for the preparation of 2-arylpropionic acids
02/03/1999EP0726891B1 A method for preparing tert-leucine and analogues thereof in enantiomeric form, and intermediates therein
02/02/1999US5866785 Recombinant plant viral nucleic acids
01/1999
01/28/1999WO1999004028A1 PROCESS FOR PREPARING OPTICALLY ACTIVE α-TRIFLUOROMETHYLLACTIC ACID AND ANTIPODE ESTERS THEREOF AND METHOD OF PURIFICATION THEREOF
01/28/1999WO1999004015A1 Microorganism and esterase obtained therefrom
01/28/1999WO1999003471A1 Improved delivery of multiple doses of medications
01/27/1999EP0893508A2 A new method for producing oxodicyclopentadiene
01/27/1999EP0893422A1 Optically active alcohol and process for the production thereof
01/26/1999US5863785 Proteins
01/20/1999EP0892044A2 Esterase and its use for the production of optically active chroman compounds
01/20/1999CN1205742A Movel process for preparing N-acetyl(L)-4-cyanophenylalanine Ac-(L)-phe(4-CN)-OH and N-acetyl-(L)-p-amidinophenylalantne-cyclohexylglycine-'beta'-(3-N-methylpyridinium)-alanine Ac-(L)-pAph-Chg-PalMe(3
01/19/1999US5861304 Enzymatic resolution of compounds using lipase or esterase from candida
01/14/1999WO1998040390A3 Oligosaccharides and the derivatives thereof, chemo-enzymatic method for the production thereof
01/13/1999EP0890649A1 Process for the preparation of acylated amino acid esters and resolving racemic mixtures of amino acid esters by enzyme-catalysed acylation
01/12/1999US5858759 D-N-carbamoyl-amino acid amidohydrolase and hydantoinase
01/06/1999CN1203949A Resolution of racemic amino esters by enzyme-catalyzed acylation
01/05/1999CA2101945C Process for producing optically active norborneol
12/1998
12/30/1998CN1203232A 2-carboxymethyl-5-(5-fluoro cyti midine-1-yl) 1,3-oxythiapentane and its derivatives
12/29/1998US5854062 Catalyzed enantiomeric selection of 1,2-diols and their cyclization to produce oxiranes
12/23/1998WO1998058073A1 Enzymatic kinetic resolution of an intermediate useful for preparing substituted tricyclics
12/23/1998EP0786012B1 Enzymatic process for the preparation of chiral-alpha-tertiary carboxylic acid esters
12/16/1998CN1201794A Process for preparation of (1S,4R)-or(1R,4S)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol
12/15/1998US5849568 Resolution of racemic indene oxide to yield (1S,2R)-indene oxide using Diplodia gossipina
12/09/1998EP0882737A1 Ligated d-protein and method of indentifying compounds that modulate receptor activity
12/09/1998EP0882138A1 Stereoselective preparation of 2-substituted succinic derivatives
12/09/1998CA2633357A1 Method for producing optically active compound
12/08/1998US5846793 Microbial process for biotransformation to (R)-3-chloro-1,2-propanediol
12/08/1998US5846792 Method of producing (R)-2-amino-1-phenylethanol and opticaly active phenylserine and their halogen substituted products using tyrosine decarboxylase
12/08/1998CA2074674C Process for preparing (2s, 3r)- or (2r, 3s)-3- (alkylphenyl) glycidic acid esters using hydrolase
12/08/1998CA2030218C Process for preparing (+) - homopilopic acid
12/03/1998WO1998054350A1 Methods and precursors for the production of chiral vicinal aminoalcohols
12/01/1998US5843765 Streptomyces microorganism useful for the preparation of (R)-baclofen from the racemic mixture
11/1998
11/26/1998WO1998053081A1 Enantioselective epoxide hydrolases and genes encoding these
11/25/1998EP0879893A1 Method of producing optically active 1,2,4-butanetriol
11/25/1998EP0879890A1 Enantioselective epoxide hydrolases and genes encoding these
11/24/1998US5841001 Process for the preparation of optically active 2-halo-1-(substituted phenyl) ethanol
11/24/1998US5840923 Chiral cyclopentene derivatives and their preparation
11/24/1998US5840553 Process for preparing 1,2-propanediol derivative compounds
11/24/1998US5840552 Using microorganisms or microbial enzyme system to produce stereospecific enantiomers; antiulcer agents
11/24/1998CA2029705C Enzymatic resolution of endo-bicyclo¬2.2.1|heptan-2-ol and derived pharmaceutical agents
11/18/1998EP0878548A2 Multistep process for the preparation of (1S,4R)- and/or (1R,4S)-4-(2-Amino-6-Chlor-9-H-purin-9-yl)-2-cyclopentene-1-methanol
11/18/1998EP0877815A1 Method of producing optically active amines
11/18/1998CN1040772C Method for obtaining gene of 2-amino-4-methylphosphinebutyric acid
11/17/1998US5837284 Oral dosage form of dl-threo methylphenidate hydrochloride; daily dosage; includes ammonio methacrylate polymer
11/12/1998WO1998050575A1 Method and apparatus for preparation of chiral beta amino acids
11/12/1998CA2287171A1 Method and apparatus for preparation of chiral beta amino acids
11/11/1998EP0876329A1 Process for the production of n-acetyl-d,l-alpha-aminocarboxylic acids
11/10/1998US5834261 Stereospecific rearrangement biosynthesis by microorganism
11/10/1998US5834259 Enzymatic decarboxylation of racemic mixture
11/10/1998US5834258 Stereoselective conversion of racemic mixtures of 5-substituted hydantoins with enzyme
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