Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
08/1994
08/10/1994EP0610048A2 Process for producing optically active alpha-hydrocarboxylic acid having phenyl group
08/09/1994US5336774 Intermediates for pharmaceuticals
08/09/1994US5336619 Using a microorganism
08/02/1994US5334535 Process for the preparation of optically pure diastereoisomers of tetrahydrofolate compounds using 10-formyltetrahydrofolate synthetase from clostridium
08/02/1994US5334534 Enzymatic preparation of optically active propanolol and β-adrenergic blockers using esterase
07/1994
07/26/1994US5332675 Optically active aromatic carboxylic acid derivatives and process for producing the same
07/26/1994US5332674 Process for preparing (R) and (S)-1,2-isopropylideneglycerol by crystallizing racemic benzoyl ester
07/12/1994US5329018 Enantiomorphs for enzyme inhibitors for HMG-CoA reductase as anticholesterol agents
07/06/1994EP0605033A1 Enzymatic process for the stereoselective preparation of a hetero-bicyclic alcohol enantiomer
07/06/1994EP0604525A1 Enzymatic production of optical isomers of tetrahydropyran-2-ones
07/06/1994EP0604483A1 Process for the preparation of enantiomerically pure 4-hydroxytetrahydro-2-pyranone derivatives
07/05/1994US5326885 Process of preparing enriched enantiomers of glycerol carbonate and derivatives thereof for synthesis of β-blockers
07/05/1994US5326705 Process for producing optically active 1,3-butandiol by asymmetric assimilation
07/05/1994US5326702 Hydrolysis of the nitrile
06/1994
06/30/1994DE4243867A1 Isomer pure myo-inositol derivs., intermediates for pharmaceuticals
06/28/1994US5324852 Ring opening optically active a-hydroxybutyrolactone; esterification
06/23/1994WO1994013828A1 Chiral arylpropionates and their use
06/22/1994EP0602740A1 Process for the enzymatic preparation of optically active transglycidic acid esters
06/22/1994EP0602247A1 Method for the preparation of d-aminoacids or d-aminoacids derivatives
06/22/1994CA2111607A1 Enzymatic process for the stereoselective preparation of a hetero-bicyclic alcohol enantiomer
06/21/1994US5322791 Enantiospecific hydrolysis
06/21/1994US5322782 Contacting alpha, beta-dihalopropionic acid with 2-halo acid dehalogenase at pH 9 or less
06/08/1994EP0599967A1 Arylalkanoic acid resolution
06/08/1994EP0599959A1 Chiral glutarate esters, their resolution and derived glutarimide compounds
05/1994
05/31/1994US5316944 Enzymatic resolution of a racemic mixture of gamma-amino acids using penicillin acylase
05/31/1994US5316943 Racemic conversion of using a transaminase
05/31/1994US5316931 Genetic engineering
05/24/1994US5314642 Hydrolysis
05/11/1994WO1994010334A1 Enantioselective production of chiral carboxylic acids
05/11/1994EP0596490A2 Stereoselective reduction of ketones
05/11/1994EP0596466A2 The process for producing D-mandelic acid
05/11/1994CA2146556A1 Enantioselective production of chiral carboxylic acids
05/10/1994US5310666 Process for the enantioselective preparation of (β-1)-hydroxyalkylxanthines by reduction using Rhodotorula rubra
05/06/1994CA2103932A1 Stereoselective reduction of ketones
05/04/1994EP0594621A1 Process for enzymatically preparing enantiomer-free esters and alcohols
05/03/1994US5308765 Esterase genes, esterase, recombinant plasmids and transformants containing the recombinant plasmid and methods of producing optically acitve carboxylic acids and their enantiomeric esters using said transformants
04/1994
04/27/1994EP0515541B1 METHOD FOR PREPARING CIS-$g(b)-PHENYLGLYCIDIC-(2R,3R) ACID
04/26/1994US5306638 Amine additive assisted enzymatic esterification of 1,2-diol monosulfonates
04/14/1994WO1994008030A1 PROCESS FOR PRODUCING D-α-AMINO ACID
04/14/1994WO1994007887A1 Optically active lactones
04/12/1994US5302528 Hydrolysis of a racemic ester mixture to the stereospecific alpha-aryl or -aryloxyalkanoic acid
04/06/1994EP0590549A1 Process for preparing thienothiopyran derivative
04/05/1994US5300437 Using omega-amino acid transaminase
03/1994
03/31/1994WO1994006930A1 A process for the preparation of enantiomeric 2-alkanoic acids
03/30/1994EP0588809A1 Process for producing chiral compounds as pure optical isomers
03/22/1994US5296373 Process for producing R(-)-mandelic acid or a derivative thereof from a mandelonitrile using rhodococcus
03/17/1994WO1994005802A1 Enzymatic asymmetric reduction process to produce 4 h-thieno(2,3-6)thio pyrane derivatives
03/17/1994WO1994005637A1 Optically active 1,4-dihydropyridine compound and process for producing the same
03/17/1994CA2143106A1 Optically active 1,4-dihydropyridine compounds and process for production thereof
03/09/1994EP0321479B1 Enzymatic membrane method for the synthesis and separation of peptides
03/08/1994US5292891 Optically active 2,2-dimethyl-1,3-dioxin-4-ones and method for preparing same and method for preparing optically active compound for synthesis of physiologically active substance and optically active intermediate compound
03/03/1994WO1994004701A1 Process for producing optically active 1,4-dihydropyridine compound
02/1994
02/23/1994EP0583979A1 Cyclohexene and cyclohexenone derivatives and process for production of cyclohexene derivatives
02/17/1994WO1994003428A1 Method of preparing optically pure precursors of paroxetine
02/17/1994CA2141843A1 Method of preparing optically pure precursors of paroxetine
02/16/1994CN1082113A Enzymatic process to separate racemic mixtures of delta valerolactones
02/15/1994US5286650 Acylation, hydrogenation of a tetramic acid; separation
02/10/1994DE4225817A1 Sepn. of racemic mixt. of delta valerolactone derivs. - by reacting a soln. of the racemic cpd. with a hydrolase, opt. in the presence of an esterifying agent to convert (2R,3R,5S) enantiomer to the (2S,3S,5R) enantiomer
02/08/1994US5284769 Process for preparing a single enantiomer of a lactam using lactamase
02/03/1994WO1994002628A1 Enzymatic resolution of a racemic mixture of stereospecific gaba-t inhibitors
02/02/1994EP0581649A1 New method of production of 20-keto 21(S)-hydroxy steroids and intermediates thereof
02/02/1994EP0580667A1 Enantiomers of cyclopentene derivatives
02/01/1994US5283346 Dioxolanes
02/01/1994US5283193 A biosynthesis of converting a racemic 2-substituted nitrile compound in presence of nitrilase or a mixture of hydratase and amidase
02/01/1994US5283182 Hydrolysis of 5-phenyl hydantoin; yields D(-)phenyl glycine or N-carbamoyl derivative; separation; recycling
01/1994
01/25/1994US5281534 Process for hydrolyzing stereoisomer esters of trans chrysanthemic acid using liver enzymes derived from horse, rabbit, pigeon or cat
01/20/1994WO1994001577A1 Process for producing optically active d-amino acid
01/20/1994WO1994001428A1 Asymmetric synthesis of hexahydrodibenzofurans by stereospecific inversion of ortho substituted 2-phenylcyclohexanols
01/19/1994EP0579370A2 An optically active 1,5-disubstituted-2,4-0-isoproylidene-2,4-dihydroxypentane and a process for producing the same
01/18/1994US5280096 Substantially pure diol and triol stereoisomers, method of preparation and polymers thereof
01/12/1994EP0578016A2 Enzymatic process for the resolution of a racemic mixture of delta-valerolactones
01/11/1994US5278070 Process for producing epoxyalcohols of high optical purity
01/11/1994US5278054 Process for the enzymatic hydrolysis of a carboxylic acid derivative
01/07/1994CA2096597A1 Enzymatic process to separate racemic mixtures of delta valerolactones
01/06/1994WO1994000593A1 Process for the preparation of substituted and optically pure 1-arylalkanols
01/06/1994WO1994000577A1 D-n-carbamoyl-amino acid amidohydrolase and hydantoinase
01/05/1994EP0577446A2 Process for preparing optically active halogen-containing alcohols
01/05/1994EP0577253A2 Enantiomeric enrichment of (R,S)-3-quinuclidinol
01/05/1994EP0576834A2 Process for producing optically active 1,2-diol derivatives
01/05/1994EP0576638A1 Process for preparing optically active cyanohydrines by racemate separation in the presence of oxynitrilases
01/05/1994EP0576471A1 Recombinant virus vectors encoding human papillomavirus proteins
01/04/1994US5276268 Phosphinothricin-resistance gene, and its use
01/04/1994US5275949 (De)cyclization
12/1993
12/29/1993EP0576002A1 Optically active 2-alkoxy-carbonyl-2-cycloalkene derivatives and a process for producing the derivatives
12/29/1993EP0575482A1 Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane
12/28/1993US5274300 Enzymatic hydrolysis of glycidate esters in the presence of bisulfite anion
12/28/1993US5274168 Optically active benzene derivatives, process for producing the same and liquid-crystalline substances containing said derivatives as active ingredient and optical switching elements
12/28/1993US5273903 Biotechnological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide
12/28/1993US5273895 Oxidizing the aldehyde or hydroxy precursor by an enzyme or Pseudomonas, Aeromonas, Escherichia and Alicaligenes
12/28/1993US5273894 Phosphinothricin-resistance gene, and its use
12/23/1993WO1993025704A1 A process for the preparation of s-(+)-2-(3-benzoylphenyl)propionic acid by enzyme-catalysed enantioselective transesterification in an organic solvent
12/23/1993WO1993025703A1 A process for the preparation of s-(+)-2-(3-benzoylphenyl)propionic acid by enzyme-catalysed enantioselective hydrolysis
12/23/1993WO1993025667A1 D-enzyme compositions and methods of their use
12/23/1993WO1993025521A1 Aryl aliphatic acids
12/21/1993US5272069 Method of producing optically active hydroxyesters
12/20/1993CA2093890A1 Enantiomeric enrichment of (r,s)-3-quinuclidinol
12/15/1993EP0573455A1 Method of preparation of pilocarpines and intermediates thereof
12/14/1993US5270206 Enzymatic resolution of endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents
12/09/1993WO1993024648A1 Microbial esterase for the enantioselective cleavage of 1-arylalkylesters
12/08/1993EP0494203B1 Synthesis of aryl alkanediols having high optical purity
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