| Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784) |
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| 03/20/2003 | US20030054510 Generation of preferential enantiomers; obtain substrate, incubate with enzyme, recover product |
| 03/20/2003 | US20030054507 Process for the preparation of the enant iomeric forms of 2-substituted 2- (2, 5-dioxoimidazolidin-1-yl) -acetic acid derivatives |
| 03/19/2003 | EP0833938B1 Reduction of ketone groups |
| 03/18/2003 | US6534523 Racemates, diastereoisomers and optical isomers of a compound of formula (I): synthesis, compositions and methods for the treatment of hepatitis C virus (HCV) infection and intermediates |
| 03/13/2003 | WO2003020943A2 Enzymatic method for the enantiomeric resolution of amino acids |
| 03/13/2003 | WO2003020929A1 Novel amide hydrolase gene |
| 03/13/2003 | WO2003020921A2 Novel pyruvate decarboxylase, production and use thereof |
| 03/12/2003 | EP1290209A1 Method for preparing an r- or s-form of alpha-substituted heterocyclic carboxylic acid and a counter enantiomeric form of alpha-substituted heterocyclic carboxylic acid ester thereto using enzyme |
| 03/12/2003 | EP1290208A1 Method for optically resolving a racemic alpha-substituted heterocyclic carboxylic acid using enzyme |
| 03/06/2003 | US20030044894 Sterilizing of transformed microorganism; generation nutrient broth, inoculate with microorganism, heat, express vector, recover heat resistant protein |
| 03/05/2003 | EP1287155A1 Enzymatic conversion of epoxides |
| 03/05/2003 | EP1082449B1 Method for stereoselective production of substituted cyclohexylcyanhydrins |
| 03/05/2003 | CN1400312A Enzyme method resolution method of racemic ornidazole |
| 03/05/2003 | CN1102661C Resolution of racemic amino esters by enzyme-catalyzed cylation |
| 03/04/2003 | US6528686 Processes for producing optically active 2-amino-1-phenylethanol derivatives |
| 03/04/2003 | US6528530 Side effect reduction; mainly the D-threo stereoisomer of a phenidate |
| 02/27/2003 | WO2003016543A2 Enzymatic resolution of t-butyl taxane derivatives |
| 02/26/2003 | EP1285962A1 NADH oxidase from Lactobacillus |
| 02/26/2003 | EP1036189B1 Resolution of chiral amines |
| 02/26/2003 | EP1003903B1 Process for preparing enantiomerically enriched n-derivatised lactams |
| 02/26/2003 | CN1399687A Method for producing optically active amines |
| 02/25/2003 | US6524844 Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent-2-ene derivatives |
| 02/25/2003 | US6524837 Hydantoinase variants with improved properties and their use for the production of amino acids |
| 02/20/2003 | WO2003014068A1 Protected 3.5-dihydroxy-2.2-dimethyl-valeronitriles for the synthesis of epothilones and derivatives and method for the production and use thereof |
| 02/20/2003 | WO2003014063A2 Protected 3.5-dihydroxy-2.2-dimethyl-valeroamides for the synthesis of epothilone and derivatives and method for the production and use thereof |
| 02/20/2003 | CA2456255A1 Protected 3.5-dihydroxy-2.2-dimethyl-valeroamides for the synthesis of epothilone and derivatives and method for the production and use thereof |
| 02/19/2003 | EP1283898A1 Process for the preparation of enantiomerically enriched esters and alcohols |
| 02/19/2003 | EP1283845A1 Process for the preparation of pharmaceutically acceptable salts of (ss-rs)-s-adenosyl-l-methionine |
| 02/19/2003 | EP0868525B1 Process for preparing intermediates for the synthesis of antifungal agents |
| 02/19/2003 | EP0795024B1 Enantioselective preparation of pharmaceutically active sulfoxides by biooxidation |
| 02/18/2003 | US6521445 Stereoselective ester hydrolysis of racemic trans-3-(4-methoxyphenyl) glycidic acid ester using a hydrolase enzyme; resolution; diltiazem production |
| 02/13/2003 | WO2003012126A2 Epoxide hydrolases, nucleic acids encoding them and methods for making and using them |
| 02/13/2003 | WO2002033110A3 PRODUCTION OF α-HYDROXY-CARBOXYLIC ACIDS USING A COUPLED ENZYME SYSTEM |
| 02/13/2003 | US20030032153 Novel (R)-2,3-butanediol dehydrogenase, methods for producing same, and methods for producing optically active alcohol using the dehydrogenase |
| 02/13/2003 | US20030032150 Generation of optically active (4R)-1,3-thiazolidine-4-carboxylic acid; obtain cells, hydrolyze optically active (4R)-1,3-thiazolidine-4- carboxylic acid amide, recover (4R)-1,3- thiazolidine-4-carboxylic acid |
| 02/13/2003 | CA2456229A1 Epoxide hydrolases, nucleic acids encoding them and methods for making and using them |
| 02/12/2003 | EP1283200A2 Optically pure paroxetine precursors |
| 02/11/2003 | US6518048 Hydrogenation a isophthalic acid derivative |
| 02/06/2003 | WO2003010312A2 Nucleic acid sequences encoding enantioselective amidases |
| 02/06/2003 | WO2003010311A2 Process for preparing variant polynucleotides |
| 02/06/2003 | WO2003010183A2 Process for preparing variant polynucleotides |
| 02/06/2003 | US20030027295 Nucleotide sequences coding enzymatic polypeptide for use in the generation insecticides |
| 02/06/2003 | CA2454701A1 Nucleic acid sequences encoding enantioselective amidases |
| 02/05/2003 | EP1228033A4 Preparing method of chiral ester |
| 02/04/2003 | US6514742 D-aminoacylases, method for producing the same, and method for producing D-amino acids using the same |
| 02/04/2003 | US6514740 Esterase gene and its use |
| 01/30/2003 | WO2003008617A1 Process for manufacturing of tagatose |
| 01/30/2003 | WO2003008569A1 Novel d-stereo specific amino acid amidase, gene thereof, preparation method thereof and production method of d-amino acid by using the same |
| 01/30/2003 | WO2003008386A2 Process for the preparation of the enantiomeric forms of 2-substituted 2-(2,5-dioxoimidazolidin-1-yl)-acetic acid derivatives |
| 01/30/2003 | WO2003008361A1 Process for the racemization of alcohols |
| 01/30/2003 | CA2453753A1 Process for the preparation of the enantiomeric forms of 2-substituted 2-(2,5-dioxoimidazolidin-1-yl)-acetic acid derivatives |
| 01/29/2003 | EP1278885A1 Resolution of aminotetralins |
| 01/29/2003 | EP0751224B1 Process for producing (r)-2-amino-1-phenylethanol or halogenated derivative thereof, process for producing optically active phenylserine or halogenated derivative thereof, and novel compound 3-(3-chlorophenyl)serine |
| 01/24/2003 | WO2002010422A1 Method for the enantioselective reduction of 8-chloro-6-oxo-octanoic acid alkyl esters |
| 01/24/2003 | CA2417119A1 Method for the enantioselective reduction of 8-chloro-6-oxo-octanoic acid alkyl esters |
| 01/23/2003 | WO2003005962A2 Methods for treatment of cognitive and menopausal disorders with d-threo methylphenidate |
| 01/23/2003 | US20030018048 Antidepressants; psychological disorders; Parkinson's disease |
| 01/22/2003 | EP0910660B1 Process for producing optically active amines |
| 01/21/2003 | US6509482 Optically active 1,4-benzodioxin-2-carboxylic acid derivatives and process for producing the same |
| 01/16/2003 | WO2002053724A3 Enzymatic deprotection of amines and hydroxides |
| 01/16/2003 | US20030013102 D-hydantoinase from Ochrobactrum anthropi |
| 01/15/2003 | EP1275723A1 Recombinant D-hydantoin hydrolases and N-carbamyl-D-amino acid hydrolases, and DNA encoding them; uses thereof for producing D-amino acids |
| 01/09/2003 | US20030008361 Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids |
| 01/09/2003 | US20030008360 Microorganisms for use in the generation of preferential cyclopentene |
| 01/08/2003 | EP1273665A1 Process for the production of optically active beta-amino alcohols |
| 01/08/2003 | CN1390192A Preparation method of chiral ester |
| 01/08/2003 | CN1390189A Method for preparing chiral ester |
| 01/03/2003 | WO2003000909A2 Methods for the manufacture of pure single enantiomer compounds and for selecting enantioselective enzymes |
| 01/03/2003 | WO2003000840A2 Nitrilases |
| 01/03/2003 | CA2677781A1 Nitrilases |
| 01/03/2003 | CA2450577A1 Methods for the manufacture of pure single enantiomer compounds and for selecting enantioselective enzymes |
| 01/02/2003 | US20030004175 Viricides |
| 01/02/2003 | US20030003552 Method for kinetic resolution of racemates of alcohols or carboxylic acid esters |
| 01/02/2003 | EP1268757A1 Nitrilase from rhodococcus rhodochrous ncimb 11216 |
| 12/26/2002 | US20020198234 Identifying a patient suffering from fatigue arising from oncological condition, and administering to the patient a therapeutically effective amount of D-threo-methylphenidate free of 1-threo isomer |
| 12/25/2002 | CN1097093C Method for resolution of aralkyl carboxylate |
| 12/24/2002 | CA2280994C O-demethylation of pharmaceutical intermediates using microorganism of the genus monosporium or thamnostylum |
| 12/19/2002 | WO2002101003A2 Stereoselective preparation of cyclic l-amino acids |
| 12/18/2002 | EP1265890A1 Stereoselective synthesis of nucleoside analogues |
| 12/12/2002 | WO2002077212A3 D-carbamoylase from arthrobacter crystallopoietes dsm 20117 |
| 12/12/2002 | WO2002048322A3 Recombinant porcine liver esterases, their use and a method for the production thereof |
| 12/11/2002 | CN1384880A L-pantolactone-hydrolase and method for producing D-pantolactone |
| 12/05/2002 | US20020182674 Generation of preferential menthol; obtain reaction mixture, incubate with lipase, recover menthol |
| 12/04/2002 | EP1262550A2 (R)-2,3-butanediol dehydrogenase, methods for producing same, and methods for producing optically active alcohol using the dehydrogenase |
| 11/26/2002 | US6486331 Substituted alkylketo compounds and process |
| 11/26/2002 | US6486323 Process for producing optically active tropinonemonocarboxylic acid derivative |
| 11/26/2002 | US6486177 Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate |
| 11/21/2002 | WO2002092828A2 Process for the preparation of substituted carboxylic acid estersby enzymatic hydrolysis |
| 11/21/2002 | US20020173012 Process for the preparation of pharmaceutically acceptable salts of (R,S)-S-adenosyl-L-methionine |
| 11/21/2002 | US20020173009 Methods for producing optically active amino acids |
| 11/20/2002 | EP1257659A2 Method and catalyst system for stereoselectively inverting a chiral center of a chemical compound |
| 11/12/2002 | US6479291 Cytoplasmic inhibition of gene expression by viral RNA |
| 11/06/2002 | CN1093880C Stabilization of carboxyl esterase |
| 11/05/2002 | US6475773 Optically purity; from alkenyl ester |
| 10/31/2002 | WO2002086126A2 Enzymatic method for the enantioselective reduction of keto compounds |
| 10/31/2002 | WO2002085519A2 High capacity methods for separation, purification, concentration, immobilization and synthesis of compounds and applications based thereupon |
| 10/31/2002 | WO2002018560A3 Butinol i esterase |
| 10/31/2002 | US20020160465 Enantioselective enzymatic aminolysis of a racemic 2-isoxazolylacetate alkyl ester |
| 10/31/2002 | US20020160398 Chlorohydroxyacetone derivative and process for producing optically active chloropropanediol derivative from the same |
| 10/31/2002 | DE10119274A1 Enzymatisches Verfahren zur enantioselektiven Reduktion von Ketoverbindungen Enzymatic method for the enantioselective reduction of keto compounds |