Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
03/1996
03/12/1996US5498786 Enzyme inhibitors, cardiovascular disorders
03/12/1996US5498625 Substantially pure enantieners of 2-azabicyclo(2.2.1)hept-5-en-3-one
02/1996
02/29/1996DE4430089A1 Enantiomeric chromane carboxylic acid derivs. prodn.
02/28/1996EP0549710B1 A process for the preparation of enantiomeric 2-alkanoic acids
02/27/1996US5494821 Process for separating optically active 1-hydroxy-cyclopentane methanol derivatives using lipase from candida or pseudomonas
02/20/1996US5493063 Process for optical resolution of 1,2-diol derivatives
02/20/1996US5492830 Enzymatic resolution of α-tertiary carboxylic acid esters
02/14/1996EP0696282A1 Process for preparing intermediates for the synthesis of antifungal agents
02/13/1996US5491260 Acylating carnitine nitrile or amide, hydrolyzing under acid conditions, lactonizing by treating with base, converting to carnitine by treating with base
02/07/1996EP0695362A1 Chiral synthesis of tertiary alcohols with a hydrolase
02/01/1996WO1996002664A1 Process for producing optically active triazole compound and method of racemizing optically active triazole compound
02/01/1996WO1995034668A3 The cytoplasmic inhibition of gene expression
01/1996
01/24/1996EP0693134A1 Arylalkanoic acid resolution
01/16/1996US5484725 Norbornane type ester hydrolase from Acetobacter pasteurianus
01/09/1996US5482847 Esterase genes, esterase, recombinant plasmids and transformants containing the recombinant plasmid and methods of producing optically active carboxylic acids and their enantiomeric esters using said trasnformants
01/04/1996WO1996000296A1 Process for producing d-amino acid by using composite immobilized enzyme preparation
01/03/1996EP0690133A1 Process for the enzymatic resolution of 2-amino-4-methyl phosphinobutanoic acid amides
01/03/1996EP0689607A1 ENANTIOSELECTIVE HYDROLYSIS OF KETOPROFEN ESTERS BY $i(BEAUVERIA BASSIANA) AND ENZYMES DERIVED THEREFROM
12/1995
12/27/1995CA2152579A1 Process for the enzymatic cleavage of 2-amino-4-methyl-phosphinobutyramide derivatives
12/26/1995US5478831 R-(-)1-(5-hydroxyhexyl)-3-methyl-7-propylxanthine, a process for its preparation and pharmaceuticals containing this compound
12/26/1995US5478734 Method of chiral epoxidation of benzopyran or pyranopyridine derivatives using microorganisms
12/21/1995WO1995034668A2 The cytoplasmic inhibition of gene expression
12/21/1995WO1995034525A1 OPTICALLY ACTIVE α-SUBSTITUTED CARBOXYLIC ACID DERIVATIVE AND PROCESS FOR PRODUCING THE SAME
12/20/1995EP0687736A1 Method for the preparation of enantiomerically pure lactams
12/20/1995EP0687305A1 Esterase and its use in biotransformation
12/19/1995US5476965 Enzymatic resolution of substituted 2-methyl-propionic acid
12/19/1995US5476791 Process for producing optically active carboxylic acid amide
12/14/1995WO1995033845A1 Process for producing optically active propargyl alcohol compound
12/13/1995EP0686698A2 Biotechnological process for the production of cyclic S-alpha-aminocarboxylic acids and R-alpha-aminocarboxylic acid amides
12/07/1995WO1995032947A1 Chiral compounds and their resolution
12/07/1995CA2191363A1 Chiral compounds and their resolution
12/05/1995US5473087 Preparation process for 20-keto 21(S) hydroxy steroids compounds and intermediates
12/05/1995US5472873 Rhodotorula rubra useful in a process for the preparation of (ω-1)-hydroxyalkylxanthines
11/1995
11/22/1995EP0683236A1 Enzymatic process for the preparation of optical active tetralin-derivatives
11/22/1995EP0683235A1 A process for the preparation of enantiomeric 2-alkanoic acids
11/22/1995EP0683145A1 A method for racemizing nitriles
11/21/1995CA2037634C Esterase and process for preparing the same
11/21/1995CA1337597C Phosphinotricin-resistance gene, and its use
11/16/1995WO1995030740A1 Process for obtaining micro-organisms containing peptide amidase, micro-organisms obtained therewith, peptide amidases contained in them and use thereof
11/16/1995DE19516018A1 Isolation of microorganisms able to produce peptide amidase by selection on two amide contg. media
11/07/1995US5464772 Process for producing optically active halogen-containing alcohols using lipase ay-120 from Candida rugosa
10/1995
10/26/1995WO1995028385A1 Synthesis n-protected amino acids, especially n-boc-l-propargylglycine by zinc-mediated addition or organic halides to glycine cation equivalent
10/26/1995WO1995028374A1 Process for producing triazole derivative
10/26/1995DE4414273A1 Optical resolution of racemic alcohols
10/26/1995CA2187733A1 Synthesis n-protected amino acids, especially n-boc-l-propargylglycine by zinc-mediated addition or organic halides to glycine cation equivalent
10/25/1995EP0678579A1 Enzymatic process for the preparation of optical active tetralin-derivatives
10/18/1995EP0677585A1 Process for the production of D-alpha-amino acids
10/17/1995US5459067 In presence of microorganism, Arthrobacter
10/11/1995EP0654025A4 Method of preparing optically pure precursors of paroxetine.
10/11/1995EP0436730B1 Method of producing d-pantolactone
10/10/1995US5457052 Process for the preparation of optically active 3-chloro-1-phenyl-propanol by a lipase catalyzed hydrolysis
10/10/1995US5457051 Enantioselective hydrolysis of ketoprofen esters by beauveria bassiana and enzymes derived therefrom
10/04/1995EP0675205A1 Enzymatic separation of racemates of asymmetric alcohols using vinyl esters of poylcarboxylic acids
10/01/1995CA2145230A1 Enzymatic resolution of asymmetric alcohols by means of vinyl esters of polybasic carboxylic acids
09/1995
09/27/1995EP0674008A1 Preparation of optically active cyclohexenol and cyclohexenyl acetic acid via an enzymatic process followed by a rearrangement reaction and their use as intermediates in the synthesis of indolobenzoquinoline derivatives
09/20/1995EP0672166A1 Enantioselective production of chiral carboxylic acids
09/20/1995EP0672165A1 A process for the preparation of s-(+)-2-(3-benzoylphenyl)propionic acid by enzyme-catalysed enantioselective transesterification in an organic solvent
09/20/1995EP0423133B1 Enzymatic resolution systems and compounds useful in the systems and their reparations
09/20/1995CN1108655A 1,3-oxathiolane nucleoside analogues
09/12/1995US5449823 Compounds and process for making a flavorant
09/12/1995US5449793 Esterification and ketalization of 1,2,4,5-pentanetetraol for preparing a HMG-CoA reductase inhibitors
09/12/1995US5449786 Method for the chemical racemization of 5-monosubstituted hydantoins by contact with anionic ion exchanger
09/08/1995WO1995023869A1 Process for producing (r)-2-amino-1-phenylethanol or halogenated derivative thereof, process for producing optically active phenylserine or halogenated derivative thereof, and novel compound 3-(3-chlorophenyl)serine
09/06/1995EP0670371A2 Process for producing optically active 4-hydroxy-2-ketoglutaric acids
09/05/1995US5447865 Method of resolution of hydroxy substituted cyclopentanone enantiomers using lipase and lithium salt complexation
09/05/1995US5447659 Optically active benzene derivatives, process for producing the same and liquid-crystalline substances containing said derivatives as active ingredient and optical switching elements
08/1995
08/30/1995EP0668925A1 Arylalkanoic acid resolution
08/30/1995EP0437555B1 Process for the racemic separation of 4-aryl-2-oxo-pyrrolidine-3-carboxylic acid esters
08/24/1995WO1995022620A1 Enzymatic resolution of substituted 2-methyl-propionic acid
08/22/1995US5443971 Separation of isomers in a mixture by selective reaction
08/22/1995US5443970 Pyranones
08/16/1995EP0440723B1 Process for preparing optically active glycidate esters
08/15/1995US5442098 Cyclohexene diol derivatives
08/15/1995US5441888 Treating racemic mandelic acid with culture broth in two steps using two different microorganisms
08/09/1995EP0556387B1 Process for preparing optically active 1,3-butanediol
08/02/1995EP0569482B1 Synthesis of intermediates in the preparation of acat inhibitors
08/01/1995CA2037043C Process for the preparation of d-pantolactone
07/1995
07/25/1995CA1336415C Manufacturing method of optically-active 1,2-diols
07/25/1995CA1336414C D-amidase and process for producing d-–-alanine and/or l-–-alanineamide
07/20/1995WO1995019373A1 Antibodies specific for d-myo-inositol 1,4,5-trisphosphate
07/12/1995EP0662149A1 A process for the preparation of enantiomeric 2-alkanoic acids
06/1995
06/27/1995US5427934 Genetic engineering process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide by microorganisms
06/22/1995WO1995016786A1 Phenylserine amides and the preparation of phenylserines/phenylserine amides
06/22/1995WO1995013386A3 Tyrosinase-activator protein fusion enzyme
06/21/1995EP0658211A1 Enzymatic asymmetric reduction process to produce 4 h-thieno(2,3-6)thio pyrane derivatives.
06/20/1995US5426211 Vinyl 2-aryl-propionates
06/14/1995EP0657544A1 Process for preparing optically active glycidate esters
06/14/1995EP0657429A1 Optically active 1,4-dihydropyridine compound and process for producing the same
06/06/1995US5422255 Culture product
05/1995
05/31/1995EP0655504A2 Process for optical resolution of 1,2-diol derivatives
05/30/1995US5420037 Process for separation of enantiomeric 3-mercapto-2-substituted alkanoic acid using lipase P30 and synthesis of captopril type compounds
05/24/1995EP0654534A2 Processes for producing optically active 2-amino-1-phenylethanol derivatives
05/24/1995EP0654533A2 A process for producing D-lactic acid and L-lactamide
05/24/1995EP0654025A1 Method of preparing optically pure precursors of paroxetine
05/18/1995WO1995013386A2 Tyrosinase-activator protein fusion enzyme
05/17/1995CN1102672A Preparation of D-alpha amino acid
05/11/1995WO1995012573A1 A method for preparing tert-leucine and analogues thereof in enantiomeric form, and intermediates therein
05/11/1995CA2173205A1 A method for preparing tert-leucine and analogues thereof in enantiomeric form, and intermediates therein
05/10/1995EP0651821A1 Enzymatic resolution of a racemic mixture of stereospecific gaba-t inhibitors.
05/09/1995US5413935 Process for selecting an enantiomer of a hydroxy lactone using pseudomonas lipase
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