Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
06/2001
06/13/2001EP1105413A2 Hepatitis c inhibitor tri-peptides
06/13/2001EP0874801B1 Process for obtaining optically active l-alpha-aminocarboxylic acids from corresponding racemic d,l-alpha-aminocarboxylic acids
06/13/2001EP0628637B1 Process for producing d-alpha-amino acids
06/07/2001WO2001040498A1 Process for the production of optically active cyclohexene derivatives and intermediates therefor
06/07/2001WO2001040450A1 Novel carbonyl reductase, gene thereof and method of using the same
06/07/2001WO2001040157A1 Method for preparing chiral esters
06/07/2001US20010003046 Process for preparing (S)-3-halogeno-1,2-propanediol by microorganism
06/07/2001CA2393336A1 Method for preparing chiral esters
06/05/2001US6242243 Pure culture; for production of hydrolase enzyme useful in efficient resolution of (+)-6-methoxy-alpha-methyl naphthalene acetic acid alkyl esters; production of naproxen
05/2001
05/31/2001WO2001038292A2 Method for producing optically active amines
05/31/2001DE19956786A1 New optically active aminoalcohol and diamine derivatives useful as intermediates, e.g. for pharmaceuticals and plant protectants
05/30/2001EP1103620A1 Process for preparing (s)-3-halogeno-1,2-propanediol by Pseudomonas
05/30/2001EP1103619A1 Process for the enantioselective preparation of aminoacids and derivatives thereof using racemization-catalysts
05/30/2001EP1102839A2 Enzyme-containing polymers
05/29/2001US6239316 Optically active secondary alcohol and process for the production thereof
05/29/2001CA2326854A1 Process for preparing (s)-3-halogeno-1,2-propanediol by microorganism
05/25/2001WO2001023535A3 Hydantoin-racemase
05/23/2001DE19955283A1 Verfahren zur enantioselektiven Gewinnung von Aminosäuren und Aminosäurederivaten unter Verwendung von Racemisierungskatalysatoren A method for the enantioselective production of amino acids and amino acid derivatives using racemization catalysts
05/22/2001US6235516 From rhodococcus globerulus, rhodococcus equi or arthrobacter aurescens
05/22/2001US6234811 Stereoselective synthesis
05/17/2001WO2001007408A3 Novel method for preparing benzoperhydroisoindole compounds
05/16/2001CN1065917C Enzyme method separation process for racemic ketoprofen
05/15/2001CA2043763C Enantiomerically selective biocatalyzed acylation
05/10/2001WO2001032890A1 L-pantolactone-hydrolase and a method for producing d-pantolactone
05/10/2001WO2001032847A1 Novel esterases derived from pseudomonas aeruginosa, its gene and process for production of optically active carboxylic acids using them
05/10/2001CA2389064A1 L-pantolactone-hydrolase and a method for producing d-pantolactone
05/09/2001EP1097236A1 Stereoselective reductive amination of ketones
05/03/2001DE19952501A1 New nucleic acid encoding L-pantolactone hydrolase, useful for producing pure D-pantolactone, an intermediate for vitamins, from its racemate
05/02/2001EP1096019A1 Process for preparing optically active 4-halogeno-1, 3-butanediol and its derivatives by microorganism
05/02/2001EP1095160A1 Method for producing (1r,4s)-2-azabicylco 2.2.1]hept-5-en-3-on derivatives
05/01/2001US6225099 Alcohol dehydrogenase and its use for the enzymatic production of chiral hydroxy compounds
04/2001
04/26/2001WO2001029245A2 ENZYMATIC PROCESS FOR THE RESOLUTION OF ENANTIOMERIC MIXTURES OF β-LACTAMS
04/26/2001WO2001028970A1 Preparing method of chiral ester
04/26/2001CA2387949A1 Preparing method of chiral ester
04/26/2001CA2386487A1 Enzymatic process for the resolution of enantiomeric mixtures of .beta.-lactams
04/26/2001CA2324395A1 Process for preparing optically active 4-halogeno-1,3-butanediol and its derivative by microorganism
04/25/2001CN1292828A Improvement in enzymatic synthesis of chiral amines
04/24/2001US6222052 Process for preparing optically active 2-amino-ω-oxoalkanoic acid derivatives
04/24/2001US6222050 As chemical intermediates useful for synthesis of (rrr)-optical isomers of 1,4-benzodioxin-2-carboxylic acid derivatives which are useful as prophylactic and therapeutic agent for diabetes, hyperglycemia
04/24/2001US6221638 Process for producing optically active amino compounds
04/24/2001CA1341217C Enantio-and regioselective syntheses of organic compounds using enol esters as irreversible transacylation reagents
04/19/2001WO2001027308A2 13-alkyl epothilone derivatives
04/19/2001WO2001027145A1 Antibody catalysis of enantio- and diastereo-selective aldol reactions
04/19/2001WO2000050623A3 Method for preparing optically active 3,3,3-trifluoromethyl-2-alkyl propionic acid derivatives
04/19/2001CA2425620A1 13-alkyl epothilone derivatives
04/18/2001CN1292034A Method for enzymatic enantiomer-separation of 3(R)-and 3(S)-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydro-pyridine or its carboxylic acid esters
04/18/2001CN1291653A Piperidine derivative, its preparation method and application
04/18/2001CN1291647A Aspergillus niger strain and its culture method and application
04/17/2001US6218581 Process of producing optically active alcohol
04/17/2001US6218156 Gene encoding carbonyl reductase, and methods for its use
04/11/2001EP0657429B1 Process for production of optically active 1,4-dihydropyridine compounds
04/11/2001CN1291236A Process for producing (R)-2-hydroxyl-1-phenoxypropane derivative
04/11/2001CN1291200A Device for producing polymer support material in form of porous polymer beand
04/10/2001US6214611 Process for the preparation of prostaglandin precursors
04/10/2001US6214610 Process for the preparation of optically active N-benzyl-3-pyrrolidinol
04/10/2001US6214609 Method and apparatus for preparation of chiral beta amino acids using penicilln G acylase
04/10/2001US6214608 Resolution of racemates of primary and secondary heteroatom-substitued amines by enzyme-catalyzed acylation
04/10/2001US6214604 Pure culture of burkholderia strain dsm 9925
04/10/2001CA2059263C Composition comprising the (-) enantiomer of cis-4-amino-1-(2-hydromethyl-1,3-oxathiolan-5-yl)-(1h)-pyrimidine-2-one or an enriched composition thereof, and its uses as a pharmaceutical agent
04/05/2001WO2001023582A1 Whole cell catalyst comprising a hydantoinase, a racemase and a carbamoylase
04/05/2001WO2001023535A2 Hydantoin-racemase
04/05/2001WO2000061734A3 Enzyme compositions and their use as catalysts
04/03/2001US6211422 Reacting substrate with crosslinked enzyme crystal catalyst in liquid or supercritical carbon dioxide fluid to produce product
04/03/2001US6210938 Antibody catalysis of enantio- and diastereo-selective aldol reactions
03/2001
03/29/2001WO2001007564A3 The use of orthoesters for the synthesis of chiral acids in biocatalyzed irreversible esterification processes
03/28/2001EP1087018A1 Aminoacylases for acylation of alcohols and amines
03/28/2001EP1087017A2 The cytoplasmic inhibition of gene expression
03/27/2001US6207429 Reacting 2,2-dimethyl-3-(substituted vinyl)cyclopropane-1-carboxylic acid c1-c4 esters with stereospecific esterase from arthrobacter to form trans-2,2-dimethyl-3-(substituted vinyl)cyclopropane-1-carboxylic acid
03/22/2001WO2001019982A2 Micro-organisms, their use and method for producing d-amino acids
03/22/2001CA2385241A1 Micro-organisms, their use and method for producing d-amino acids
03/15/2001DE19942812A1 Verfahren zur Herstellung von D-(3'-Pyridyl)-alanin Process for the preparation of D- (3'-pyridyl) -alanine
03/14/2001EP1083170A1 Method for producing D-(3'-Pyridyl)-alanine
03/14/2001EP1082449A1 Method for stereoselective production of substituted cyclohexylcyanhydrins
03/13/2001US6201147 Process for the resolution of esters of arylalkylcarboxylic acids
03/08/2001WO2001016090A1 Enantiomerically-enriched compounds having photocleavable bond(s) and methods related thereto
03/08/2001CA2384191A1 Enantiomerically-enriched compounds having photocleavable bond(s) and methods related thereto
03/07/2001EP1081228A2 Process for producing carboxylic acid isomer
02/2001
02/28/2001CN1285410A Process for producing leve diketone microbe
02/21/2001EP1076718A1 Novel method for preparing synthesis intermediates
02/20/2001US6191292 Precursors of the A-ring of vitamin D and method and intermediates for the preparation thereof
02/20/2001CA2001115C Biocatalysts
02/15/2001WO2001011073A1 Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids
02/15/2001WO2001011072A1 Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids
02/14/2001EP1075534A1 Improvements in the enzymatic synthesis of chiral amines
02/13/2001US6187936 Transesterification of mixture of trans enantiomers catalysed by enzymes in organic solvent with aminoalcohols to give mixture of trans esters, non transesterified and transesterified, having opposite configuration, separating
02/13/2001US6187582 Process for producing optically active amines
02/08/2001DE19935268A1 N-Acetylaminosäureracemase N-acetylamino acid
02/08/2001DE19933362A1 Verfahren zur Herstellung von L-Aminosäuren aus ihren racemischen N-Acetyl-D,L-Derivaten durch enzymatische Racemat-Spaltung mittels isolierter, rekombinanter Enzyme A method for producing L-amino acids from their racemic N-acetyl-D, L derivatives by enzymatic resolution by means of isolated, recombinant enzymes
02/07/2001EP1074630A2 Microbial production of levodione
02/07/2001EP1074628A1 N-Acetylamino acid racemase
02/07/2001EP1073762A1 Enzymatic resolvation for obtaining a (-)-3,4-trans-diarylchroman
02/06/2001US6184008 Production of optically active sphingoid compound
02/02/2001CA2315837A1 Microbial production of levodione
02/01/2001WO2001007623A1 Epoxide hydrolases from streptomyces
02/01/2001WO2001007564A2 The use of orthoesters for the synthesis of chiral acids in biocatalyzed irreversible esterification processes
02/01/2001WO2001007408A2 Novel method for preparing benzoperhydroisoindole compounds
02/01/2001DE19935113A1 Epoxidhydrolasen aus Streptomyces Epoxide hydrolases from Streptomyces
02/01/2001CA2379859A1 Novel method for preparing benzoperhydroisoindole compounds
01/2001
01/31/2001EP1071807A1 Method for enzymatic enantiomer-separation of 3(r)- and 3(s)-hydroxy-1- methyl-4-(2,4, 6-trimethoxyphenyl)-1, 2,3,6- tetrahydro-pyridine or its carboxylic acid esters
01/30/2001US6180639 Therapy for human immunodeficiency virus
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