| Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784) |
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| 07/11/2000 | CA2062281C Biotechnological process for the production of s-(+)-2,2-dimethylcyclopropanecarboxamide |
| 07/06/2000 | WO2000039324A2 Method for producing optically active 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives |
| 07/05/2000 | EP0882138B1 Stereoselective preparation of 2-substituted succinic derivatives |
| 07/05/2000 | EP0639180B1 Process for stereospecific hydrolysis of piperidinedione derivatives |
| 06/29/2000 | WO2000037668A1 Process for the preparation of optically active alpha-aminonitriles |
| 06/29/2000 | WO2000037666A1 Process for producing (r)-2-hydroxy-1-phenoxypropane derivative |
| 06/29/2000 | WO2000037657A1 Process for the enzymatic preparation of amino acid derivatives with enhanced optical purity |
| 06/29/2000 | WO2000037631A1 Process for the production of enzymes with altered catalytic activity relative to an amino acid substrate and enzymes so produced |
| 06/29/2000 | WO2000037619A2 Mutant epoxide hydrolases |
| 06/29/2000 | WO2000037486A1 Synthesis and recovery of aspartame involving enzymatic deformylation step |
| 06/29/2000 | DE19857302A1 Verfahren zur enantioselektiven Reduktion von 3,5-Dioxocarbonsäuren und deren Ester A process for the enantioselective reduction of 3,5-Dioxocarbonsäuren and esters thereof |
| 06/29/2000 | CA2321450A1 Process for producing (r)-2-hydroxy-1-phenoxypropane derivative |
| 06/28/2000 | EP1013773A1 Process for the preparation of optically active alpha-aminonitriles |
| 06/28/2000 | EP1013769A1 Process for the enzymatic preparation of amino acid derivatives with enhanced optical purity |
| 06/28/2000 | EP1013768A1 Mutant epoxide hydrolases |
| 06/22/2000 | WO2000036134A1 Method for the enantioselective reduction of 3,5-dioxocarboxylic acids, their salts and their esters |
| 06/13/2000 | US6075156 Cycloaddition reaction cyclopentadiene and vinyl acetate, also generating a pressure above 4 atmospheres, then esterifying with a carboxylic acid, biotransformation with an enzyme |
| 06/07/2000 | EP1005563A1 METHOD FOR PRODUCING CYCLIC $g(a)-AMINO ACIDS FREE FROM ENANTIOMERS OR THEIR N-PROTECTED DERIVATIVES BY MEANS OF A D-SPECIFIC AMINOACYLASE |
| 06/07/2000 | CN1255551A Stereo selective microbe reduction of dltetralinone |
| 06/07/2000 | CN1255496A Application of heterobicyclic alcohol antimer for preparing piperazine derivative |
| 05/31/2000 | EP1003903A1 Process for preparing enantiomerically enriched n-derivatised lactams |
| 05/31/2000 | EP1003902A1 Method for racemic biochemical resolution of cis- and trans- pyrrolopiperidine |
| 05/31/2000 | EP1003885A1 Microorganism and esterase obtained therefrom |
| 05/31/2000 | CN1254760A Microbe process for preparing (4R, 6R)-4-hydroxyl-2,2,6-trimethyl cyclohexanone |
| 05/30/2000 | US6069272 Simplified method for the production of vinyl glycine (2-aminobut-3-enoic acid) and a convenient resolution of a derivative |
| 05/30/2000 | US6068986 Antibodies specific for d-myo-inositol 1,4,5-trisphosphate and the enzyme-linked immunosorbent assay of d-myo-inositol 1,4,5-trisphosphate |
| 05/30/2000 | CA2031784C Process for the preparation of optically pure diastereoisomers of tetrahydrofolate compounds |
| 05/25/2000 | WO2000009543A3 Hepatitis c inhibitor tri-peptides |
| 05/25/2000 | DE19850433A1 New coenzyme A derivatives useful for the synthesis of L(-)-carnitine and gamma-butyrobetaine |
| 05/24/2000 | EP1002123A1 Enzymatic kinetic resolution of an intermediate useful for preparing substituted tricyclics |
| 05/24/2000 | EP1002097A2 Dehydrogenases with improved nad-dependence, the production thereof, and their use |
| 05/24/2000 | EP1001772A1 Improved delivery of multiple doses of medications |
| 05/18/2000 | WO2000028007A2 Chemically modified mutant serine hydrolases |
| 05/18/2000 | CA2348014A1 Chemically modified mutant serine hydrolases |
| 05/17/2000 | EP1001036A2 Enzymatic processes for resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes |
| 05/16/2000 | US6063919 Esterification of o-deprotected dibenzyl exochelic acid with benzyl epi-cobactin, hydrogenolytically removing the three benzyl groups to form exochelin 786sm(r) |
| 05/16/2000 | US6063615 Enzymatic acylation of amino acid esters using a carboxylic acid ester substituted with oxygen on the alpha carbon |
| 05/11/2000 | WO2000026351A1 (S)-α-PHENETHYLAMINE : PYRUVATE TRANSAMINASE |
| 05/11/2000 | CA2317028A1 (s)-.alpha.-phenethylamine : pyruvate transaminase |
| 05/09/2000 | US6060290 Esterase and methods for the production of optically active chroman compounds |
| 05/04/2000 | WO2000024923A1 The enzyme-mediated synthesis of peptidomimetics |
| 05/04/2000 | WO2000024919A1 Coenzymes useful for the synthesis of l-carnitine |
| 05/04/2000 | DE19850426A1 New gamma-butyrobetainyl-coenzyme A, useful for activating L(-)-carnitine dehydratase, especially for preparing L(-)-carnitine from crotonobetaine |
| 05/03/2000 | EP0997535A2 Stereoselective microbial reduction of a racemic tetralone |
| 05/03/2000 | EP0997534A2 Process for the resolution of racemic arylalkylcarboxylic acid esters |
| 05/03/2000 | EP0784697B1 Bacterial process for the resolution of racemic cis-diols |
| 05/02/2000 | US6057479 Multistage reaction of hydroxy indanone with amine to form imine, heating and hydrogenation |
| 05/02/2000 | US6057452 Process to prepare taxol |
| 05/02/2000 | US6057121 Method of catalyzing stereochemical reactions |
| 04/27/2000 | WO2000023608A1 Preparation of amino alcohols |
| 04/27/2000 | WO2000023598A1 Aminoacylase and its use in the production of d-aminoacids |
| 04/27/2000 | WO2000023577A1 Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase |
| 04/27/2000 | CA2347079A1 Aminoacylase and its use in the production of d-aminoacids |
| 04/25/2000 | US6054566 Recombinant animal viral nucleic acids |
| 04/20/2000 | WO2000022157A1 Non-homogeneous systems for the resolution of enantiomeric mixtures |
| 04/20/2000 | DE19848129A1 New nucleic acid sequence encoding Alcaligenes faecalis nitrilase polypeptide useful for converting racemic nitriles to chiral carboxylic acids |
| 04/19/2000 | CN1251095A Lipase capalyzed dynamic resolution of isoxazoline thioester to isoxazoline carboxylic acids |
| 04/13/2000 | WO2000020623A1 Resolution of trans-2 -(alkoxycarbonylethyl) -lactams useful in the synthesis of 1- (4-fluorophenyl) -3(r) -[3(s) -hydroxy-3 -(4-fluorophenyl) -propyl)] -4(s) -(4-hydroxyphenyl) -2-azetidinone |
| 04/12/2000 | EP0991772A1 Methods and precursors for the production of chiral vicinal aminoalcohols |
| 04/06/2000 | WO2000018946A1 Process for producing optically active tropinone monocarboxylic acid derivative |
| 04/06/2000 | DE19844876A1 Optical resolution of arylalkanoic acid vinyl or isopropenyl ester, useful in rapid preparation of optically pure chiral carboxylic acids, by enantio-selective transesterification in presence of lipase or esterase |
| 04/05/2000 | CN1249348A Method for resolution of aralkyl carboxylate |
| 04/04/2000 | US6046354 Chemical intermediates, e.g. 2-aryl-1,3-diacyloxy-2-propanol, for drugs and fungicides,e.g. (r)-2-(2,4-difluorophenyl)-3-(1h-1,2,4-triazole-1-yl)-propane-1,2-diol, |
| 04/04/2000 | CA2033278C Method of producing optically active hydroxyesters and methods of purifying and producing optically active five-membered ring lactones |
| 03/30/2000 | WO2000017384A1 Process for the enzymatic kinetic resolution of 3-phenylglycidates by transesterification with aminoalcohols |
| 03/29/2000 | EP0989187A2 Microbial biotransformation using microorganisms of the genus Monosporium or Thamostylum |
| 03/23/2000 | WO1999047684A3 Dehydrogenases with improved nad-dependence, the production thereof, and their use |
| 03/22/2000 | CN1248258A Method for producing heteroaromatic alcohols free of enantiomers |
| 03/21/2000 | US6040133 D-enzyme compositions and methods of their use |
| 03/21/2000 | CA2018773C Enantiomeric enrichment and stereoselective synthesis of chiral amines |
| 03/15/2000 | CN1247572A Method for producing esters free of enantiomers |
| 03/14/2000 | US6037166 Enzymatic kinetic resolution of an intermediate useful for preparing substituted tricyclics |
| 03/14/2000 | US6037158 Lactobacillus alcohol dehydrogenase which reacts with acetophenone to form r-phenylethanol |
| 03/09/2000 | WO2000012745A1 Method for preparing (2r)-piperidine derivatives |
| 03/09/2000 | WO2000005354A3 Enzyme-containing polymers |
| 03/09/2000 | CA2341554A1 Process for the preparation of (2r)-piperidine derivatives |
| 03/08/2000 | EP0984013A2 Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1, 3-oxathiolane |
| 03/08/2000 | EP0983367A1 Enantioselective epoxide hydrolases and genes encoding these |
| 03/02/2000 | WO2000011203A1 Enzyme-catalyzed racemic cleavage of primary amines |
| 03/01/2000 | EP0982406A2 Microbial production of actinol |
| 03/01/2000 | CN1246157A Enzymatic resolution of benzodiazepine-acetic acid esters with lipase |
| 02/29/2000 | US6030823 For industrial production of d-amino acids from n-acetyl-d-amino acids |
| 02/24/2000 | WO2000009547A1 Novel process for the synthesis of exochelins |
| 02/24/2000 | WO2000009543A2 Hepatitis c inhibitor tri-peptides |
| 02/24/2000 | WO1999051722A3 Recombinant l-n-carbamoylase derived from arthrobacter aurescens, and a method for producing l-amino acids by using the same |
| 02/24/2000 | DE19837745A1 Optical resolution of primary amines by enantioselective acylation with a long-chain alkoxyalkanoate or phenoxyalkanoate ester in the presence of a lipase |
| 02/24/2000 | CA2338781A1 Novel process for the synthesis of exochelins |
| 02/23/2000 | EP0980860A1 Optically active secondary alcohol and process for the production thereof |
| 02/22/2000 | US6027926 Method of producing optically active 1,2,4-butanetriol |
| 02/19/2000 | CA2280350A1 Microbial production of actinol |
| 02/16/2000 | EP0979303A1 Method and apparatus for preparation of chiral beta amino acids |
| 02/10/2000 | WO2000006562A1 Optically active 1,4-benzodioxine-2-carboxylic acid derivatives and process for producing the same |
| 02/10/2000 | DE19835533A1 Optically active lactone preparation in high enantiomeric purity from unsaturated acid, by oxygen transfer from peroxide and microbial or enzymatic conversion, used e.g. as aroma or insect attractant |
| 02/09/2000 | EP0978567A1 Process for producing optically active alcohols |
| 02/08/2000 | US6022977 Dynamic resolution of isoxazoline thioesters to isoxazoline carboxylic acids |
| 02/03/2000 | WO2000005354A2 Enzyme-containing polymers |
| 02/03/2000 | CA2337884A1 Enzyme-containing polymers |
| 02/02/2000 | EP0976828A1 Fungal D-aminoacylases and method for producing D-amino acids |
| 01/27/2000 | WO2000004179A1 Stereoselective reductive amination of ketones |
| 01/27/2000 | DE19832547A1 Production of enzyme-containing polymers useful as biocatalysts with longer activity stability |