Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
07/2002
07/10/2002EP1220898A2 Hydantoin-racemase
07/10/2002CN1087349C novel process for preparing N-acetyl(L)-4-cyanophenylamine Ac-(L)-phe(4-CN)-OH and N-acetyl-(L)-P-amidinophenylalantne-cyclohexylglycine-beta-(3-N-methylpyridinium)alanine Ac-(L)-pAph-Chg-palme(3)-NH2
07/10/2002CN1087348C Resolution of receme of heteroatom-bustituted primary amine and secondary amine by enzymatic acylation
07/04/2002US20020088024 Nucleotide sequences coding enzymatic protein for use in the treatment of lysosomal storage defects
07/03/2002EP1219715A1 Process for preparation of (R)-1,2-propanediol by microbes
07/02/2002US6413752 Protein capable of catalyzing transamination stereoselectively, gene encoding said protein and use thereof
07/02/2002US6413750 Enzyme having mutation in n-terminal sequence which changes alkalinity of cofactor binding site
06/2002
06/27/2002WO2002050125A2 Glycosaminoglycans derived from k5 polysaccharide having high antithrombin activity and process for their preparation
06/26/2002EP1216304A1 Whole cell catalyst comprising a hydantoinase, a racemase and a carbamoylase
06/26/2002CA2365805A1 Process for preparation of (r) -1,2-propanediol by microbes
06/25/2002US6410531 For therapy of hepatitis c virus (hcv) infection
06/25/2002US6410279 Generating preferential compound in solution; obtain n-substituted azetidine-2-carboxylic acid ester, incubate with preferential enzyme, recover compound
06/20/2002WO2002048383A1 Process for producing optically active (4r)-1,3-tiazolidine-4-carboxylic acid
06/20/2002WO2002048322A2 Recombinant porcine liver esterases, their use and a method for the production thereof
06/20/2002WO2002004384A3 Process for preparing (-)menthol and similar compounds
06/18/2002US6407284 Contacting with enzyme; hydrolysis
06/18/2002US6406912 Method for enzymatic enantiomer-separation of 3(r)- and 3(s)-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydro-pyridine or its carboxylic acid esters
06/18/2002US6406904 Preparing 1,2,4-butanetriol by culture of pseudomonas broths and isolation
06/18/2002US6406898 Recombinant protein with pantolactone activity
06/18/2002CA2041837C Enzyme capable of reducing acetophenone and other carbonyl compounds and processes therefor
06/11/2002US6403824 Process for the preparation for 4,5-diamino shikimic acid derivatives
06/11/2002US6403357 Thermostable D-hydantoinase and the application thereof
06/05/2002EP1211312A2 Method for sterilizing transformed cells
06/05/2002CN1352695A Method for producing optically active 1-amino-4-hydroxymethyl-cyclopent-2-ene derivatives
06/04/2002US6399339 Simple and efficient process using alcohol dehydrogenase in presence of a cofactor
06/04/2002CA2070640C D-pantolactone hydrolase and process for the preparation thereof
05/2002
05/30/2002US20020065316 Citrullimycines, a process for their production and their use as pharmaceuticals
05/30/2002US20020064847 Polypeptide for use generation of preferential compounds
05/29/2002EP1208079A1 Enantiomerically-enriched compounds having photocleavable bond(s) and methods related thereto
05/28/2002US6395535 Optical resolution of 4-halogeno-3-alkanoyloxy-butyronitrile
05/23/2002WO2002040438A1 Preparation of enantiomerically pure hydroxy esters and acids
05/23/2002US20020062019 Glycosaminoglycans derived from K5 polysaccharide having high anticoagulant and antithrombotic activities and process for their preparation
05/23/2002US20020061565 Monitoring preferential compounds in racemic; obtain enantiomer, incubate with racemic mix, hydrolyze mix, recover preferential compound
05/23/2002DE10055512A1 L-Aminosäure-Oxidase aus Rhodococcus-Arten L-amino acid oxidase from Rhodococcus species
05/22/2002EP1206565A1 Process for the preparation of substituted 3-phenyl-propanoic acid esters and substituted 3-phenyl-propanoic acids
05/22/2002EP1206452A2 Novel method for preparing benzoperhydroisoindole compounds
05/21/2002US6391597 Generating preferential carboxylic acid compound; obtain preferential ester, incubate hydrolase, recover preferential compound
05/16/2002WO2002038784A1 Enzyme catalysis in the presence of ionic liquids
05/15/2002EP1205555A1 Enzymatic catalysis in the presence of ionic liquids
05/15/2002EP1205542A1 L-amino acid oxidase from Rhodococcus
05/15/2002CN1084745C Method for preparing 1,3-oxythiapentane and its derivatives
05/14/2002US6387692 Process for the preparation of optically active amines
05/14/2002US6387668 Crude or pure enzyme preparation from agrobacterium species; for selectively degrading epichlorohydrin
05/14/2002CA2241210C Novel process for preparing n-acetyl(l)-4-cyanophenylalanine ac-(l)-phe(4-cn)-oh and n-acetyl-(l)-p-amidinophenylalanine-cyclohexylglycine-.beta.-(3-n-methylpyridinium)-alanine ac-(l)-paph-chg-palme(3)-nh2
05/10/2002WO2002036795A2 Process for preparing (-)- menthol and similar compounds
05/10/2002WO2002002753A3 Nucleotide sequence encoding benzaldehyde lyase and method for the stereoselective synthesis of 2-hydroxy ketones
05/09/2002WO2002036803A1 Process for producing d-serine
05/08/2002CN1348500A Novel method for preparing synthesis intermediates
05/02/2002EP1200601A1 Method for the production of l-amino acids from their racemic n-acetyl-d, l-derivatives by enzymatic racemate cleavage by means of isolated recombinant enzymes
05/02/2002EP1076718B1 Novel method for preparing synthesis intermediates
05/02/2002EP0801683B1 Racemate separation of primary and secondary heteroatom-substituted amine by enzyme-catalysed acylation
04/2002
04/30/2002US6379936 With crotonobetainyl-coenzyme a and l(-)-carnitine dehydratase, adding d(+)-carnitine and isolating l-isomer
04/25/2002WO2002033110A2 PRODUCTION OF α-HYDROXY-CARBOXYLIC ACIDS USING A COUPLED ENZYME SYSTEM
04/25/2002US20020049342 Substituted alkylketo compounds and process
04/25/2002US20020049219 Preparing 5,6-substitued-5,6,7,8-tetrahydronaphthalen-2-ol compounds by selectively deacylating the corresponding 2-ester with a hydrolytic enzyme; estrogen agonists
04/25/2002US20020048797 Fungicidal mixture; for killing plant parasites
04/25/2002DE10050124A1 Verwendung der Acetylaminosäureracemase aus Amycolatopsis orientalis Racemisierung von Carbamoylaminosäuren Use of Amycolatopsis orientalis from acetylamino acid racemization of carbamoyl
04/25/2002DE10050123A1 Verfahren zur Herstellung von Aminosäuren A process for the production of amino acids
04/25/2002CA2426594A1 Production of .alpha.-hydroxy-carboxylic acids using a coupled enzyme system
04/24/2002EP1199369A2 Use of the acetylamino acid racemase from Amycolatopsis orientalis in the racemization of carbamoylamino acids
04/23/2002US6376752 Cytoplasmic inhibition of gene expression in a plant
04/23/2002US6376230 Stereoselective process for producing intermediates of cryptophycins
04/18/2002US20020045238 Thermostable D-hydantoinase and the application thereof
04/17/2002EP1197563A1 Method for Producing Amino Acids
04/17/2002EP1196622A2 The use of orthoesters for the synthesis of chiral acids in biocatalyzed irreversible esterification processes
04/17/2002EP1196590A1 Epoxide hydrolases from streptomyces
04/16/2002US6372459 For producing enantiomer-enriched amino acids, and derivatives
04/16/2002CA2053955C Methods of preparing optically active epoxy alcohol and intermediate prepared in the process of the methods
04/11/2002WO2002029079A2 Enantioselective production of amino carboxylic acids
04/11/2002WO2002028824A1 Citrullimycines, a process for their production and their use as pharmaceuticals
04/11/2002US20020042537 Method for producing lysine derivative
04/11/2002US20020042108 Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent -2- ene derivatives
04/11/2002CA2424273A1 Citrullimycines, a process for their production and their use as pharmaceuticals
04/11/2002CA2359648A1 Process for the production of amino acids
04/11/2002CA2358853A1 Use of acetyl amino acid racemase from amycolatopsis orientalis for racemisation of carbomoyl amino acids
04/09/2002US6368850 Preparing 1-amino-4-(hydroxymethyl)-2-cyclopentene and n-acetylamino-alcohol hydrolase activity obtainable from these microorganisms.
04/04/2002US20020039769 Chemical intermediates; hydrolysis using hydrolases
04/03/2002EP1193249A1 Citrullimycines, a process for their production and their use as pharmaceuticals
04/03/2002EP0862646B1 Production of optically active 2-substituted tetrahydropyran-4-ones
04/02/2002US6365399 Process for producing carboxylic acid isomer using Nocardia diaphanozonaria or Saccharopolyspora hirsuta
04/02/2002US6365398 Process for preparation to stereoisomeric carboxylic acid esters
04/02/2002US6365380 Method for stereoselectively inverting a chiral center of a chemical compound using an enzyme and a metal catalyst
03/2002
03/28/2002US20020037998 For therapy of hepatitis C virus (HCV) infection
03/28/2002US20020037559 Microorganism which can utilize an N-protected proline derivative of given general formula in the form of the racemate or an optically active isomer; simplification; N-acyl-L-proline acylase
03/26/2002US6361987 Useful for preparing intermediates for the synthesis of optically active 1,4-dihydropyridine derivatives which are well known per se and useful as prophylactic and therapeutic agents for ischemic heart diseases, hypertension
03/21/2002WO2002022849A2 Enzymatic resolution of aryl- and thio-substituted acids
03/21/2002WO2002022844A1 Optically active fluorophenylalanine derivative and process for producing the same
03/21/2002US20020035126 Side effect reduction
03/21/2002US20020034776 Genetically engineering enzymatic proteins; transform eschericha, generate mutations, transmit mutation to another microoganism and detect enzymatic activity, recover microorganism with adjusted enzymatic activity
03/21/2002CA2422466A1 Enzymatic resolution of aryl- and thio-substituted acids
03/20/2002EP1188826A2 5-substituted hydantoin racemase, DNA coding for the same, and process for producing optically active amino acids
03/14/2002WO2002020821A2 Process for the preparation of enantiomerically enriched amines
03/14/2002WO2002020820A1 Method for the preparation of enantiomerically enriched amines
03/14/2002DE10042892A1 New butynol I esterase, for stereospecific hydrolysis or transesterification of esters, to produce optically active reaction products
03/12/2002US6355656 Phenidate drug formulations having diminished abuse potential
03/07/2002WO2002018560A2 Butinol i esterase
03/07/2002WO2001062948A3 Method and catalyst system for stereoselectively inverting a chiral center of a chemical compound
03/07/2002US20020028957 Optically active 1,4-benzodioxin-2-carboxylic acid derivatives and process for producing the same
03/07/2002CA2419275A1 Butinol i esterase
03/05/2002US6352848 Nucleotide sequences of amino acid sequences
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