Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
02/2002
02/28/2002WO2001038292A3 Method for producing optically active amines
02/28/2002US20020025567 Hydroxylation in presence of enzyme
02/28/2002US20020025565 Method for optically resolving a racemic alpha-substituted heterocyclic carboxylic acid using enzyme
02/28/2002US20020025549 Synthesis and recovery of aspartame involving enzymatic deformylation step
02/27/2002EP1182205A1 Chiral diphosphines via 2,3 -sigmatropic rearrangement.Application in asymmetric transition metal catalysis
02/21/2002US20020022640 Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
02/14/2002WO2002012472A1 Stereoselective esterase from aspergillus oryzae
02/14/2002WO2001048175A3 METHODS FOR PRODUCING ENANTIOMERICALLY PURE α-SUBSTITUTED CARBOXYLIC ACIDS
02/14/2002US20020019034 Process for preparation of optically active 1,2-diols by cultivating microorganisms
02/13/2002EP1179599A2 Method for producing lysine derivative
02/13/2002EP1179595A1 (r)-2-octanol dehydrogenase, process for producing the enzyme, dna encoding the enzyme and process for producing alcohol by using the same
02/13/2002EP0865500B1 Process for the preparation of optically active amines
02/12/2002US6346632 Crystallization of esters of methoxyphenylglycidic acid from alcohol solvents
02/12/2002US6346402 Acts on optically active (s)-alpha-phenethylamine and pyruvic acid to form acetophenone and alanine; for producing chemical intermediates of drugs and agricultural chemicals
02/07/2002WO2002010399A1 Novel carbonyl reductase, gene thereof and method of using the same
02/07/2002US20020016442 Hepatitis C inhibitor tri-peptides
02/07/2002DE10056025A1 Verfahren zur enantioselektiven Reduktion von 8-Chlor-6oxo-octansäurealkylestern Octanoic acid alkyl esters of 8-chloro-6oxo-process for the enantioselective reduction of
02/07/2002DE10037101A1 Rekombinant hergestellte Enzyme mit verbesserter NAD(H)-Akzeptanz Recombinantly produced enzymes with improved NAD (H) -Akzeptanz
02/07/2002CA2384625A1 Novel carbonyl reductase, gene thereof and method of using the same
02/06/2002CN1334344A Enzyme resolution process for prepairng chiral-trans-chrysanthemum monocarboxylic acid
02/05/2002US6344351 (R)-transaminase from arthrobacter
01/2002
01/31/2002WO2002008439A1 Process for the preparation of 2-amino acids
01/31/2002WO2002008404A2 Production of lysosomal enzymes in plants by transient expression
01/31/2002WO2001044492A3 Method for kinetic resolution of racemates of alcohols or carboxylic acid esters
01/31/2002US20020012975 Culture product containing Rhodococcus
01/31/2002US20020012974 Methods for producing enantiomerically pure alpha-substituted carboxylic acids
01/30/2002EP1176203A1 Enzyme with improved NAD(H)-acceptance
01/29/2002US6342629 Process for production of optically active n-protected-n-methyl-phenylalanine derivative
01/29/2002CA2165996C Stereoselective preparation of 2-substituted succinic derivatives
01/24/2002US20020010360 Process for the preparation of aminoalcohol derivatives and their further conversion to (1R, 4S)-4-((2-amino-6-chloro-5-formamido-4-pyrimidinyl)-amino)-2-cyclopentenyl-1- methanol
01/24/2002US20020010147 High purity of the diastereoisomer; acidifying pH, making an aqueous lysate from the yeast, microfiltration of lysate, absorption on a weak acid resin, elution with inorganic acid, decoloration, reverse osmosis, adding acid to form salt
01/24/2002DE10032254A1 Nukleotidsequenz kodierend für eine Benzaldehyd-Lyase und Verfahren zur stereoselektiven Synthese von 2-Hydroxyketonen Nucleotide sequence encoding a benzaldehyde lyase and methods for the stereoselective synthesis of 2-hydroxyketones
01/23/2002EP1173585A1 Epoxide hydrolases of aspergillus origin
01/23/2002EP0833937B1 Optical resolution of alkyl 1,4-benzodioxan-2-carboxylates using esterase from serratia marcescens
01/22/2002US6340587 Treating racemic mixture with acylase; isolating pure enantiomorph of n-protected (1r,4s)-2-azabicyclo(2.2.1)hept-5-en-3-one
01/17/2002WO2002004384A2 Process for preparing (-)menthol and similar compounds
01/17/2002US20020006960 Neuraminidase inhibitors
01/17/2002US20020006651 To convert ethyl 4-chloroacetoacetate using NADPH as a coenzyme to produce ethyl (S)-4-chloro-3-hydroxybutyrate; substrate specificity, no activity to ethyl acetoacetate, specified optimal pH and temperature; enzyme from candida
01/17/2002US20020006644 Method for preparing an R- or S-form of alpha-substituted heterocyclic carboxylic acid and a counter enantiomeric form of alpha-substituted heterocyclic carboxylic acid ester thereto using enzyme
01/17/2002US20020006635 Stereoselectively hydrolyzing an anomeric mixture of 2-benzoyloxydioxolanecarboxylate with an enzyme; separating product; replacing carboxylate by reaction with a purine or pyrimidinyl derivative
01/16/2002CN1331743A Method for producing chiral carboxylic acids from nitriles with assistance of nitrilase or microorganisms which contain gene for nitrilase
01/10/2002WO2002002753A2 Nucleotide sequence encoding benzaldehyde lyase and method for the stereoselective synthesis of 2-hydroxy ketones
01/10/2002WO2001057232B1 Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives
01/09/2002EP1169467A1 Process for the preparation of prostaglandin precursors
01/09/2002EP1169435A2 Enzyme compositions and their use as catalysts
01/09/2002CN1330721A Resolution of trans-2-(alkoxycarbonylethyl)-laitams useful in synthesis of 1-(4-fluorophenyl)-3(R)-[3(s)-hydroxy-3-(flurophenyl)-propyl)]-4(s)-(4-hydroxyphenyl)-2-azetidinone
01/08/2002US6337197 Coenzymes useful for the synthesis of L-carnitine
01/08/2002US6337196 Enzymatic processes for preparing (S)-cyanohydrins
01/03/2002WO2002000585A1 Chlorohydroxyacetone derivative and process for producing optically active chloropropanediol derivative from the same
01/02/2002EP1167534A2 Process for the preparation of optically active 1,2-diols by cultivating microorganisms
01/02/2002EP1165829A1 THE PREPARATION OF (trans)-4-AMINO-2-CYCLOPENTENE-1-CARBOXYLIC ACID DERIVATIVES
01/02/2002EP1165763A1 Hydantoinase variants with improved properties and their use for the production of amino acids
01/02/2002EP1165507A1 Biocatalyst and its use in enzymatic resolution of racemic beta-lactams
01/02/2002EP0783039B1 Process for producing optically active 2-alkoxycyclohexanol derivatives
01/02/2002CN1329671A Non-homogeneous systems for resolution of enantiomeric mixtures
01/01/2002US6335187 Resolution of chiral amines
12/2001
12/28/2001CA2351913A1 Process for preparation of optically active 1,2-diols by cultivating microorganisms
12/27/2001US20010055798 Process for the enzymatic resolution of lactams
12/25/2001US6333176 Enzymatic cleavage of c-terminal amino group from peptide amide, deamination with peptide amidase, incubation and inoculation
12/20/2001DE10029194A1 New isolated nucleic acid encoding L-pantolactone hydrolase, useful for production of optically pure D-pantolactone from its racemate
12/19/2001CN1326743A Process for preparing 1,3-oxygen-sulphur cyclopentane nucleotide like medicine composition
12/13/2001WO2001027308A3 13-alkyl epothilone derivatives
12/12/2001EP0745137B1 Enzymatic resolution of substituted 2-methyl-propionic acid
12/11/2001US6329533 Chemical intermediate for antidiabetic drug
12/11/2001US6329417 Hepatitis C inhibitor tri-pepitides
12/11/2001US6329379 Oligopeptides for inhibiting hepatitis
12/06/2001WO2001092554A1 Method for preparing an r- or s-form of alpha-substituted heterocyclic carboxylic acid and a counter enantiomeric form of alpha-substituted heterocyclic carboxylic acid ester thereto using enzyme
12/06/2001WO2001092553A1 Method for optically resolving a racemic alpha-substituted heterocyclic carboxylic acid using enzyme
12/06/2001US20010049127 Process for the preparation of D-asparagine derivatives
12/06/2001CA2410441A1 Method for preparing an r- or s-form of alpha-substituted heterocyclic carboxylic acid and a counter enantiomeric form of alpha-substituted heterocyclic carboxylic acid ester thereto using enzyme
12/06/2001CA2410438A1 Method for optically resolving a racemic alpha-substituted heterocyclic carboxylic acid using enzyme
12/04/2001CA1341324C Esterase enzymes used in the process for the preparation of 2-arylpropionic acids
11/2001
11/29/2001WO2001090397A1 Enzymatic conversion of epoxides
11/29/2001WO2001090396A1 Process for the preparation of enantiomerically enriched esters and alcohols
11/29/2001WO2001090130A1 Process for the preparation of pharmaceutically acceptable salts of (ss-rs)-s-adenosyl-l-methionine
11/29/2001CA2410529A1 Process for the preparation of enantiomerically enriched esters and alcohols
11/28/2001EP1158054A1 Enzymatic conversion of epoxides
11/27/2001US6323180 Protease inhibitors; inhibit replication of hepatitis c virus
11/27/2001CA2018562C Process for the enzymatic cleavage of vinyl 2-aryl-propionates
11/27/2001CA2005421C A process for the preparation of l-phosphinothricin
11/22/2001US20010044142 Microbial reductase useful for the stereoselective reduction of a racemic tetralone
11/21/2001EP1156120A2 Enzymatic resolution of selective estrogen receptor modulators
11/21/2001EP1155695A1 1,3 oxathiolane nucleoside analogues
11/21/2001EP1155138A2 Method for preparing optically active 3,3,3-trifluoromethyl-2-alkyl propionic acid derivatives
11/21/2001CN1323316A 丙型肝炎三肽抑制剂 Tripeptide inhibitor of hepatitis C
11/21/2001CN1322842A Enzyme dividing method for selective estrogenic hormone acceptor regulator
11/21/2001CN1322707A Producing process for triazole derivant
11/21/2001CN1074924C Preparing method for medical composition containing 1,3-oxathiolane nucleoside analogues
11/15/2001US20010041717 Chronic, bolus administration of D-threo methylphenidate
11/15/2001US20010041359 Process for the preparation of optically and chemically highly pure (R) - or (S) -alpha- hydroxycarboxylic acids
11/14/2001EP0576471B1 Recombinant virus vectors encoding human papillomavirus proteins
11/13/2001US6316233 Generating preferentially halogenated compounds using pseudomonas; culture cells, mix with halogenated substrate, isolated preferentially halogenated compounds
11/08/2001WO2001083807A1 Resolution of aminotetralins
11/08/2001CA2407776A1 Resolution of aminotetralins
11/07/2001EP1152054A1 Novel carbonyl reductase, gene thereof and method of using the same
11/07/2001EP1151992A1 Method for purifying and isolating (2s,3s)- or (2r,3s)-halohydrin derivatives
11/07/2001EP1151133A1 Stereoselective synthesis of nucleoside analogues
11/07/2001EP1151130A1 Coenzymes useful for the synthesis of l-carnitine
11/01/2001US20010036660 Reacting a a-keto acid with methylamine
11/01/2001US20010036653 Stereo-specific synthesis of shimikic acid derivatives with improved efficiency
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