| Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784) |
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| 03/05/2015 | WO2015030010A1 Method for producing pyrrole derivative, and intermediate thereof |
| 03/03/2015 | US8969051 Process for producing optically active 2-alkyl-1,1,3-trialkoxycarbonylpropane |
| 02/18/2015 | EP2837689A1 Optical resolution method for bicyclic compound using enzyme |
| 02/17/2015 | US8956840 Engineered ketoreductase polypeptides |
| 02/11/2015 | CN104350035A 制备曲前列环素及其衍生物的方法 Prepared treprostinil and its derivatives |
| 02/11/2015 | CN104342478A R-1-(2,3-二甲基苯基)乙醇及其酯的合成 Synthesis of R-1- (2,3-dimethylphenyl) ethanol and its esters |
| 02/11/2015 | CN102753702B 旋光性3-取代戊二酸单酰胺的制备方法 Method for preparing optically active 3-substituted glutaric acid monoamide |
| 02/04/2015 | CN102409074B 一种光学纯2-氨基-2'-羟基-1,1'-联萘的酶拆分方法 An optically pure 2-amino-2'-hydroxy-1,1'-binaphthyl enzymatic resolution methods |
| 02/03/2015 | US8946507 Method of selectively producing male or female sterile plants |
| 02/03/2015 | US8945890 Method for producing monoterpene and monoterpinoid compounds and use thereof |
| 01/21/2015 | CN104293875A 生物酶催化制备(s)-2-氯苯甘氨酸甲酯单一对映体的方法 (S) -2- chlorophenyl glycine methyl ester individual enantiomers were prepared biocatalysis |
| 01/21/2015 | CN104292074A R-1-(2,4-二甲基苯基)乙醇及其酯的合成 Synthesis of R-1- (2,4-dimethylphenyl) ethanol and its esters |
| 01/15/2015 | WO2015005341A1 Method for manufacturing optically active fluorolactic acid derivative |
| 01/15/2015 | WO2015004015A1 Biocatalyzed synthesis of the optically pure (r) and (s) 3-methyl-1,2,3,4-tetrahydroquinoline and their use as chiral synthons for the preparation of the antithrombotic (21r)- and (21s)-argatroban |
| 01/14/2015 | EP2824187A1 Biocatalyzed synthesis of the optically pure (R) and (S) 3-methyl-1,2,3,4-tetrahydroquinoline and their use as chiral synthons for the preparation of the antithrombotic (21R)- and (21S)-argatroban |
| 01/13/2015 | US8932837 Amidase and use thereof for producing 3-aminocarboxylic acid esters |
| 01/08/2015 | WO2015001330A1 Lactate production process |
| 01/07/2015 | CN104263803A 动态动力学拆分制备s-2-四氢萘胺 Dynamic Kinetic Resolution for preparing s-2- tetralin amine |
| 01/07/2015 | CN104263802A 动态动力学拆分制备s-1-四氢萘胺 Dynamic Kinetic Resolution for preparing s-1- tetrahydro-naphthylamine |
| 01/07/2015 | CN104263801A 一种r-2-四氢萘胺的制备方法 A process for preparing tetrahydro-naphthylamine-2- r |
| 01/07/2015 | CN104263800A S-2-四氢萘胺的制备方法 Preparation S-2- tetralin amine |
| 01/07/2015 | CN104263799A 一种s-2-四氢萘胺的制备方法 Method for preparing s-2- tetralin amine |
| 01/07/2015 | CN104263798A S-1-四氢萘胺的制备 Preparation of S-1- tetrahydro-naphthylamine |
| 01/07/2015 | CN104263797A R-1-四氢萘胺的制备 Preparation of R-1- tetrahydro-naphthylamine |
| 01/07/2015 | CN104263796A 一种r-1-四氢萘胺的制备方法 One kind of r-1- Preparation of tetrahydro-naphthylamine |
| 01/07/2015 | CN104263795A 制备手性α-环烷基甘氨酸的方法 Preparation of Chiral α- cycloalkyl method glycine |
| 01/07/2015 | CN104262115A 一种r-1-(4-甲氧基苯基)乙醇及其酯的合成方法 One kind of r-1- (4- methoxyphenyl) ethanol and its esters synthesis |
| 01/07/2015 | CN104262096A 一种r-1-(4-溴苯基)乙醇及其酯的合成方法 One kind of r-1- synthesis (4-bromophenyl) ethanol and its esters |
| 01/07/2015 | CN104262095A R-1-(4-氟苯基)乙醇及其酯的合成 Synthesis of R-1- (4- fluorophenyl) ethanol and its esters |
| 01/07/2015 | CN104262094A 一种r-1-(4-氯苯基)乙醇及其酯的合成方法 One method of synthesis r-1- (4- chlorophenyl) ethanol and its esters |
| 01/07/2015 | CN104262093A R-1-(3-甲基苯基)乙醇及其酯的合成 R-1- (3- methylphenyl) ethanol and esters Synthesis |
| 01/07/2015 | CN104262092A R-1-(2-甲基苯基)乙醇及其酯的合成 R-1- (2- methylphenyl) ethanol and esters Synthesis |
| 01/07/2015 | CN104262091A R-1-(2,5-二甲基苯基)乙醇及其酯的合成 Synthesis of R-1- (2,5-dimethylphenyl) ethanol and its esters |
| 12/31/2014 | CN103333942B 左旋吡喹酮的合成方法 Synthesis of L praziquantel |
| 12/25/2014 | US20140377798 Process for the enzymatic regeneration of redox cofactors |
| 12/24/2014 | CN104245951A 使用酶对二环化合物光学拆分的方法 Using enzymes bicyclic compound optical resolution methods |
| 12/24/2014 | CN104232730A 酶法生产一种手性四氢吡唑并嘧啶的工艺 Enzymatic production of one chiral tetrahydro pyrazolopyrimidine process |
| 12/18/2014 | US20140370556 Method for preparing (r)-praziquantel |
| 12/17/2014 | CN104212738A 解淀粉芽孢杆菌wzz002及应用 Bacillus amyloliquefaciens wzz002 and application |
| 12/17/2014 | CN104211626A 新型维生素d受体活化剂及制造方法 The new vitamin d receptor activation and manufacturing method |
| 12/09/2014 | US8906663 Nitrilases |
| 12/02/2014 | US8900830 Process for producing optically active succinimide derivatives |
| 10/07/2014 | US8852904 Protein complex having activity catalyzing asymmetric oxidation reaction and process for producing the same |
| 10/01/2014 | EP2783004A1 Diterpene synthases and method for producing diterpenoids |
| 09/30/2014 | US8846366 R-hydroxynitrile lyase (R-HNL) random variants and their use for preparing optically pure, sterically hindered cyanohydrins |
| 09/25/2014 | WO2014148929A1 Method of enzymatic resolution of serine racemic derivative |
| 09/18/2014 | WO2014140006A1 Process for enantioselective synthesis of 3-hydroxy-glutaric acid monoesters and use thereof |
| 09/17/2014 | EP2778229A1 Process for the enantioselective preparation of 3-hydroxyglutaric acid monoesters and their use |
| 09/09/2014 | US8828691 Process for resolving cyclopropyl diesters |
| 09/03/2014 | EP2772547A1 Method for enzymatic synthesis of (7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid, and use for the synthesis of ivabradine and the salts thereof |
| 08/13/2014 | CN103981248A 一种拆分外消旋亮氨酸的方法 One kind of resolution of racemic leucine method |
| 08/13/2014 | CN102628075B 一种青霉素酰化酶拆分生产手性氨基酸的方法及其产品 Penicillin acylase production of chiral amino acids split method and products |
| 08/06/2014 | EP2762565A1 Novel amidase |
| 08/06/2014 | CN103966192A 一种具有拆分消旋体γ-内酰胺活性的（-）γ-内酰胺酶及其编码基因与应用 Having γ- Separation of racemic lactam activity (-) γ- lactamase coding gene and application |
| 07/31/2014 | US20140212957 Production of optically pure propane-1,2-diol |
| 07/23/2014 | CN103937867A 一种以大豆慢生根瘤菌全细胞拆分消旋体β-内酰胺的方法 A slow-growing soybean rhizobia in the whole cell splitting method racemic β- lactam |
| 07/16/2014 | CN102086462B 手性单体扁桃酸的获得方法 Method of obtaining chiral mandelic acid monomer |
| 07/15/2014 | US8778651 Nitrilases, nucleic acids encoding them and methods for making and using them |
| 07/10/2014 | WO2014030106A3 Process for procuding (2r,3s)-3-(4-methoxyphenyl)glydidic acid ethyl ester by enantioselective hydrolysis of racemic 3(4-methoxyphenyl)glycidic acid methyl ester employing lipase derived from serratia marcescens and/or candida cylindracea |
| 07/09/2014 | CN102586384B 一种通过dl-氨基酸去消旋化制备d-氨基酸的生物催化方法 By dl- a biocatalytic process for the preparation of amino acid to amino acid racemization d- |
| 07/08/2014 | CA2495881C Evolving new molecular function |
| 07/02/2014 | EP2748303A1 A novel bacterial strain of achromobacter sp. mtcc 5605 and a highly enantioselective epoxide hydrolase isolated therefrom |
| 07/02/2014 | CN102925529B 制备左旋吡喹酮的中间体及左旋吡喹酮的方法 Preparation of L and L praziquantel praziquantel intermediate approach |
| 07/02/2014 | CN102925528B 一种制备左旋吡喹酮的中间体及左旋吡喹酮的方法 A process for preparing L-L praziquantel praziquantel intermediates and methods |
| 06/26/2014 | WO2013174848A3 Process for the preparation of treprostinil and derivatives thereof |
| 06/19/2014 | WO2014092496A1 Method for preparing optically active amine compound using deracemization |
| 06/18/2014 | CN103865976A Method of biochemically separating 8-benzyl-7, 9-dioxo-2, 8-diazo bicycle [4.3.0] nonane |
| 06/18/2014 | CN101889081B Ketoreductase polypeptides and uses thereof |
| 06/11/2014 | CN1849391B Nitrilases, nucleic acids encoding them and methods for making and using them |
| 06/11/2014 | CN103857384A Method for the synthesis of porphyrin-phospholipid conjugates |
| 06/11/2014 | CN103114122B Method for preparing trans-4-aminomethyl-naphthenic acid from Actioplanes sp. |
| 06/11/2014 | CN103013945B Epoxide hydrolase mutant as well as gene and application of epoxide hydrolase mutant |
| 06/11/2014 | CN102839141B Enterobacter capable of producing esterase, esterase and gene as well as application in preparation of taxol chiral precursor |
| 06/11/2014 | CN102719512B Preparation method for R-2-(4- hydroxyphenoxy) propionate |
| 06/04/2014 | EP2737074A1 Process for producing l-carnitine from beta-lactones employing lipases |
| 06/04/2014 | CN103842505A Novel amidase |
| 06/04/2014 | CN103045504B Microorganism catalysis prepared (2S,3R)-2-benzoyl aminomethyl-3-hydroxybutyric acid ester and bacterial strain |
| 06/03/2014 | CA2430192C Enzymes having dehalogenase activity and methods of use thereof |
| 05/28/2014 | CN103820521A 生物催化动态动力学拆分制备r-邻氯扁桃酸甲酯的方法 Biocatalysis dynamic kinetic resolution r- Chloromandelic methyl ester method |
| 05/28/2014 | CN103820417A 一种酯水解酶、编码基因、载体、工程菌及其应用 An ester hydrolase encoding gene, vector, engineering bacteria and its application |
| 05/28/2014 | CN103820416A 一种高立体选择性酯水解酶、编码基因及其应用 A highly stereoselective ester hydrolase encoding gene and its Applications |
| 05/27/2014 | CA2443377C D-hydantoinase from ochrobactrum anthropi |
| 05/21/2014 | EP2732043A2 Separation process |
| 05/21/2014 | EP2732042A1 Separation process |
| 05/21/2014 | EP2732041A1 Separation process |
| 05/21/2014 | CN102392066B 有效分离外消旋体制备纯手性物的方法 The method of effective separation of racemic prepared from pure chiral matter |
| 05/15/2014 | WO2014073673A1 Protein complex capable of catalyzing asymmetric oxidation reaction and method for producing same |
| 05/14/2014 | CN102605034B 一种制备光学纯（s）-5-（4-氟苯基）-5-羟基戊酸甲酯的生物酶拆分法 An optically pure (s) Preparation of 5- (4-fluorophenyl) -5-hydroxy pentanoate The enzymatic resolution method |
| 05/14/2014 | CN102559833B 离子液体共溶剂生物拆分制备(s)-(+)-2，2-二甲基环丙烷甲酸的方法 Preparation of bio-resolution ionic liquid co-solvent (s) - (+) - 2,2- dimethyl-cyclopropane carboxylic acid method |
| 05/07/2014 | CN101611141B R-hnl随机变体及其用于制备光学纯的空间位阻氰醇的用途 R-hnl random variants and for the preparation of optically pure sterically hindered the use of cyanohydrin |
| 04/23/2014 | CN103160562B Method of synthetizing levo-praziquantel |
| 04/23/2014 | CN102911996B Method for preparing levo-praziquantel |
| 04/22/2014 | CA2622894C New esterases and their use for processes for kinetic resolution of butinolesters |
| 04/16/2014 | EP2717857A1 Method for the synthesis of porphyrin-phospholipid conjugates |
| 04/16/2014 | CN102796719B (+)Gamma-lactamase, its coding gene and application |
| 04/09/2014 | EP2716629A1 Method for producing optically active alpha-substituted proline |
| 04/02/2014 | CN103703138A Process for producing l-carnitine from beta-lactones employing lipases |
| 03/27/2014 | WO2014045036A1 Lactate production process |
| 03/26/2014 | CN103687955A Separation process |
| 03/26/2014 | CN103667242A Preparation method and application of immobilized aspergillus terreus lipase |