| Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784) |
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| 04/22/1998 | CN1179770A Preparation of cis- 4 -0 -protected -2 -cyclopentenol derivatives |
| 04/08/1998 | EP0833938A1 Reduction of ketone groups |
| 04/08/1998 | EP0833937A1 Optical resolution of alkyl 1,4-benzodioxan-2-carboxylates using esterase from serratia marcescens |
| 04/07/1998 | US5736385 Nitrilase or nitrile hydratase hydrolysis of a cyanohydrin while automatically controlling cyanohydrin concentration |
| 04/01/1998 | EP0832191A1 Recombinant viral nucleic acids |
| 03/31/1998 | US5733756 Using an amidase as biocatalyst to make the free acid of methylphenidate, d-threo-2-(piperid-2-yl)-2-phenylacetic acid |
| 03/31/1998 | US5733754 Enzyme and its use in preparing (S)-pipecolic acid |
| 03/31/1998 | US5733749 Glycerol phosphatase with stereo-specific activity |
| 03/25/1998 | CN1177382A Process for preparing optically active amines |
| 03/24/1998 | US5731464 Process for preparation of indenol |
| 03/24/1998 | US5731175 Method of producing (R)-2-amino-1-phenylethanol and optically active phenylserine and their halogen substituted products using microbes |
| 03/18/1998 | CN1176635A Chiral derivatives of hydroxyphenylglycin, and their use in the synthesis of pharmaceutical active principles |
| 03/17/1998 | US5728899 Reduction of ketones to form alcohols |
| 03/17/1998 | US5728876 Reaction of amines with ester in the presence of protease or lipse for acylation |
| 03/12/1998 | WO1998010091A1 Process for preparing optically active isomers of 2-halo-2-fluorocyclopropanecarboxylic acids |
| 03/12/1998 | WO1998010075A1 Microorganism, lactamase enzyme obtained therefrom, and their use |
| 03/11/1998 | CN1037682C Process for preparing 2 -hydroxymethyl -5 -(5 -fluorocytosin -1 -yl) -1 ,3 -oxathiolane |
| 03/04/1998 | EP0826065A1 Enzymatic hydrolysis of 3,3-diethyl-4- (4-carboxy)phenoxy]-2-azetidinone esters |
| 03/04/1998 | EP0826032A1 BIOTECHNICAL PRODUCTION PROCESS OF PIPERAZINE R-$g(a)-CARBOXYLIC ACIDS AND PIPERAZINE S-$g(a)-CARBOXYLIC ACID AMIDE |
| 03/03/1998 | US5723321 Microorganisms |
| 02/19/1998 | WO1998001568A3 Method of preparing (s) - or (r) -3,3,3-trifluoro-2-hydroxy-2- methylpropionic acid |
| 02/17/1998 | US5719308 Enzymatic process for the preparation of optically active tetralin derivatives |
| 02/17/1998 | US5719054 Recombinant virus vectors encoding human papillomavirus proteins |
| 02/10/1998 | US5717116 Process for producing (R)-styrene oxides |
| 02/10/1998 | US5716841 Process for the resolution of ethyl 4,4,4-trifluoro-3(R)-hydroxybutanoate using lipase from candida |
| 02/05/1998 | WO1998004733A1 Production of amino acids and enzymes used therefor |
| 02/05/1998 | CA2262016A1 Production of amino acids and enzymes used therefor |
| 02/04/1998 | CN1172504A Pacemate separation of primary and secondary heteroatom-substituted amine by enzyme-catalysed acylation |
| 02/03/1998 | US5714642 Resolution of immixtures of stereoisomeric alcohols |
| 02/03/1998 | US5714357 Biosynthesis comprising a microorganism of the genus rhodococcus, alcaligenes, pseudomonas or brevibacterium capable of asymmetrically hydrolyzing a nitrile group of a racemic alpha-hydroxynitrile |
| 02/03/1998 | US5714355 Biologically pure culture of mutant microorganism |
| 02/03/1998 | US5714351 Cyclopentenes |
| 01/27/1998 | CA1339644C Method of preparing beta-2',2'-difluoronucleosides |
| 01/22/1998 | WO1998002568A1 The bioresolution of n-acylazetidine-2-carboxylic acids |
| 01/22/1998 | WO1998002556A2 Screening for and use of an esterase for a stereospecific resolution |
| 01/22/1998 | CA2259402A1 The bioresolution of n-acylazetidine-2-carboxylic acids |
| 01/20/1998 | US5710272 Increasing cerebral blood flow |
| 01/15/1998 | WO1998001568A2 Method of preparing (s) - or (r) -3,3,3-trifluoro-2-hydroxy-2- methylpropionic acid |
| 01/15/1998 | DE19725802A1 Preparation of 3,3,3-tri:fluoro-2-hydroxy-2-methyl propionic acid, |
| 01/14/1998 | EP0818438A1 Chiral derivatives of hydroxyphenylglycin, and their use in the synthesis of pharmaceutical active principles |
| 01/14/1998 | EP0817764A1 Preparation of cis-4-o-protected-2-cyclopentenol derivatives |
| 01/13/1998 | US5707837 Method of producing (R)-tertiary leucine |
| 01/13/1998 | US5707825 Interface bioreactor system |
| 01/07/1998 | EP0672165B1 A process for the preparation of s-(+)-2-(3-benzoylphenyl)propionic acid by enzyme-catalysed enantioselective transesterification in an organic solvent |
| 01/02/1998 | DE19624292A1 Preparation of optically pure 1'-hydroxy-benz-bromoarone |
| 12/30/1997 | US5702928 Asymmetric synthesis by ester interchange or hydrolysis catalyzed by microbial lipase |
| 12/29/1997 | EP0813530A1 Novel process for preparing 2,3-dihydro-benzofuranol derivatives |
| 12/29/1997 | EP0687305B1 Esterase and its use in biotransformation |
| 12/18/1997 | WO1997038124A3 Enzymatic process for stereoselective preparation of therapeutic amides |
| 12/17/1997 | EP0812819A2 Enantiomer-enriched tertiary hydrocarbonrest-substituted malonic acid ester and the preparation |
| 12/17/1997 | EP0812363A1 Process for preparing optically active amines |
| 12/16/1997 | US5698696 Cyclization; protecting; deprotecting; hydroboration/oxidation; resolution; esterification; reduction |
| 12/11/1997 | WO1997046698A1 Process for producing optically active amines |
| 12/10/1997 | EP0599967B1 Arylalkanoic acid resolution |
| 12/09/1997 | US5696299 Interesterification in the presence of a heat resistant lipase and in the absence of water or solvent |
| 12/09/1997 | US5695968 Process for production of D-α-amino acids |
| 12/04/1997 | WO1997045551A1 Process for the preparation of optically active methadones in high enantiomeric purity |
| 12/04/1997 | WO1997045529A1 Process for the preparation of amino alcohols and derivatives thereof |
| 12/04/1997 | DE19622168A1 Recovery of individual isomers from mixtures using cells or microorganisms |
| 12/04/1997 | DE19621686A1 Verfahren zur Herstellung von optisch aktiven Aminen A process for producing optically active amines |
| 12/04/1997 | CA2256011A1 Process for the preparation of optically active methadones in high enantiomeric purity |
| 12/03/1997 | EP0644949B1 A process for the preparation of s-(+)-2-(3-benzoylphenyl)propionic acid by enzyme-catalysed enantioselective hydrolysis |
| 11/27/1997 | WO1997044480A1 Enzymatic synthesis of optically active hydroxamic acids and their conversion into optically active primary amines by lossen transposition |
| 11/27/1997 | DE19634446A1 Enzymatische Synthese optisch aktiver Hydroxamsäuren und ihre Umsetzung zu optisch aktiven primären Aminen durch Lossen-Umlagerung Enzymatic synthesis of optically active hydroxamic acids and their conversion to optically active primary amines by Lossen rearrangement |
| 11/27/1997 | CA2253866A1 Enzymatic synthesis of optically active hydroxamic acids and their conversion into optically active primary amines by lossen transposition |
| 11/26/1997 | CN1166182A D-pantolactone hydrolase and gene encoding the same |
| 11/18/1997 | US5688933 Preparation of biologically active compounds from substantially pure enantiomers of 2-azabicyclo 2.2.1!hept-5-en-one |
| 11/13/1997 | WO1997042167A1 Process to prepare taxol |
| 11/13/1997 | CA2251703A1 Process to prepare taxol |
| 11/11/1997 | US5686285 Norbornane type ester hydrolase |
| 11/06/1997 | WO1997041214A1 Biocatalysts with amine acylase activity |
| 11/05/1997 | EP0804600A1 The cytoplasmic inhibition of gene expression |
| 10/22/1997 | EP0801683A1 Racemate separation of primary and secondary heteroatom-substituted amine by enzyme-catalysed acylation |
| 10/22/1997 | CN1036196C 1,3-Oxatholane nucleoside analogues |
| 10/16/1997 | WO1997038124A2 Enzymatic process for stereoselective preparation of therapeutic amides |
| 10/16/1997 | CA2251634A1 Enzymatic process for stereoselective preparation of therapeutic amides |
| 10/15/1997 | EP0801135A1 Enzymatic resolution of endo-bicyclo (2.2.1)heptan-2-ol |
| 10/14/1997 | US5677168 Enantioselective enzymatic hydrolysis using lipase from horse liver acetone powder, pseudomonas or candida to give mixture of unhydrolyzed r-acetate and s-alcohol |
| 10/14/1997 | US5677155 Reacting 1-bromodecane with tetrahydropyranyl ether of propargyl alcohol, deprotecting, catalytically hydrogenating, oxidizing, stereoselectively acylating in presence of lipase, recovering optically active alcohol, tosylating, alkylating |
| 09/30/1997 | US5672504 Process for enriching an R,S!-1,2-epoxide in one enantiomer by using microbes to convert one enantiomer to the other or to preferentially open the epoxide ring |
| 09/24/1997 | EP0796914A2 Alcohol dehydrogenase and its use in the enzymatic production of chiral hydroxy-compounds |
| 09/24/1997 | CN1160421A Enzymatic process for preparation of chiral-alpha-t-carboxylic acid esters |
| 09/23/1997 | US5670662 Pyranones |
| 09/18/1997 | WO1997033987A1 Process for producing n-protected d-proline derivatives |
| 09/18/1997 | CA2245543A1 Process for producing n-protected d-proline derivatives 8 |
| 09/17/1997 | EP0795609A2 Process for preparing optically active trans-3-phenylglycidamide compounds |
| 09/17/1997 | EP0795025A1 Enantioselective preparation of pharmaceutically active sulfoxides by bioreduction |
| 09/17/1997 | EP0795024A1 Enantioselective preparation of pharmaceutically active sulfoxides by biooxidation |
| 09/17/1997 | EP0795023A1 A process for producing sulphoxide enriched in the (r) or the (s) enantiomer |
| 09/15/1997 | CA2199880A1 Process for preparing optically active trans-3- phenylglycidamide compounds |
| 09/11/1997 | DE19715465A1 Preparation of (R)-3-quinuclidinol from (R,S)-3-quinuclidinol |
| 09/10/1997 | EP0794251A1 D-pantolactone hydrolase and gene encoding the same |
| 09/09/1997 | US5665598 Synthesis of chiral N-protected-α-substituted-glycine free acids by zinc-mediated addition of organic halide to glycine cation equivalent |
| 09/09/1997 | US5665575 Microbial esterase for the enantioselective cleavage of 1-phenylethyl acetate |
| 09/03/1997 | EP0792936A2 Process for the preparation of optically active 2-halo-1-(substituted phenyl) ethanol |
| 09/02/1997 | USH1679 Process for preparing an optically pure intermediate for a phosphonosulfonate soualene synthetase inhibitor |
| 09/02/1997 | US5663329 With bacteria |
| 08/26/1997 | US5661014 Cyclization of ester-nitrile; biotransformation |
| 08/20/1997 | EP0529085B1 Process for producing optically active 3-chloro-1-phenyl-1-propanol and derivative thereof |
| 08/19/1997 | US5658796 Optical resolution of alkyl chroman-2-carboxylates |