Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
10/2001
10/31/2001EP1149849A1 Process for the production of covalently bound biologically active materials on polyurethane foams and the use of such carriers for chiral syntheses
10/30/2001US6309881 Aldehyde and ketone reactants are contacted with antibody molecules or molecules containing antibody combining site portions that catalyze an aldol addition reaction
10/30/2001CA2030073C Enantioselective amidases, dna sequences encoding them, method of pre paration, and utilization
10/25/2001WO2001019982A3 Micro-organisms, their use and method for producing d-amino acids
10/25/2001DE10019380A1 Verfahren zur Herstellung von kovalent gebundenen biologisch aktiven Stoffen an Polyurethanschaumstoffen sowie Verwendung der geträgerten Polyurethanschaumstoffe für chirale Synthesen Process for the preparation of covalently bonded biologically active substances on polyurethane foams and the use of supported polyurethane foams for chiral syntheses
10/25/2001DE10019377A1 Immobilization of biologically active substances, especially enzymes, comprises contacting a foamed polymeric material with the substance
10/24/2001EP1148140A1 Process for the preparation of D-asparagine derivatives
10/24/2001EP1148042A2 Method for producing optically and chemically pure (R)- and (S)-hydroxycarboxylic acids
10/23/2001US6307064 Process to prepare taxol
10/23/2001US6306634 Esterase gene and its use
10/18/2001US20010031487 Process for producing optically active amino compounds
10/17/2001EP1146036A2 Tamiflu, Gallocarboxylic acid approach
10/17/2001CN1317481A Method for preparing 4,5-diamino shikimic acid derivative
10/17/2001CA2344004A1 Process for the preparation of optically and chemically highly pure (r)- or (s)-a-hydroxycarboxylic acids
10/16/2001US6303349 Contacting chroman-3-acetic acid ester with ester hydrolase to hydrolyze to chroman-3-acetic acid
10/16/2001CA2176236C Tyrosinase-activator protein fusion enzyme
10/10/2001EP1141374A2 Method for producing optically active 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives
10/10/2001EP1141373A1 Method for the enantioselective reduction of 3,5-dioxocarboxylic acids, their salts and their esters
10/10/2001EP1141369A1 Process for the preparation of optically active alpha-aminonitriles
10/10/2001EP1141333A1 Process for the enzymatic preparation of amino acid derivatives with enhanced optical purity
10/09/2001US6300106 Method of preparing 3-[2-{(Methylsulfonyl)oxy}-ethoxy ]-4-(triphenylmethoxy)-1-butanol, methane sulfonate
10/04/2001WO2001073100A1 PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE β-AMINO ALCOHOLS
10/04/2001WO2001029245A8 ENZYMATIC PROCESS FOR THE RESOLUTION OF ENANTIOMERIC MIXTURES OF β-LACTAMS
10/04/2001CA2404668A1 Process for producing optically active .beta. -amino alcohols
10/03/2001CN1315962A Novel process for synthesis of exochelins
09/2001
09/25/2001US6294374 Use of catalytic antibodies for synthesizing epothilone
09/19/2001EP0638077B1 Chiral cyclopentene derivatives and their preparation
09/19/2001CN1313905A Enzyme-catalyzed racemic cleavage of primary a mines
09/18/2001US6291701 Used as chemical intermeidate
09/18/2001US6291679 Process for preparing benzoperhydroisoindole compounds
09/13/2001US20010021521 Crotonobetanyl-coenzyme A is prepared from crotonobetaine hydrochloride and coenzyme A, characterised in that crotonobetainyl chloride is prepared form crotonobetaine hydrochloride and subsequently transformed by coenzyme A
09/13/2001US20010021519 Method and catalyst system for stereoselectively inverting a chiral center of a chemical compound
09/11/2001US6287829 Process for the selective enzymatic hydroxylation of aldehydes and ketones
09/07/2001WO2001064857A1 Nitrilase from rhodococcus rhodochrous ncimb 11216
09/07/2001CA2400446A1 Nitrilase from rhodococcus rhodochrous ncimb 11216
09/06/2001DE10010149A1 New nucleic acid encoding nitrilase, useful for converting aromatic nitriles to carboxylic acid, pharmaceutical intermediates, isolated from Rhodococcus rhodochrous
09/05/2001EP1130109A1 Microbial process for preparation of optically active 3-Hydroxypyrrolidine derivatives
09/05/2001EP1130108A1 Methods for racemizing N-acylamino acids and producing optically active amino acids
09/05/2001EP1130107A1 Method of producing optically active N-methylamino acids
09/05/2001EP1129180A2 Chemically modified mutant serine hydrolases
09/05/2001CN1311333A Micro-organism method for prepn. of optical 3-hydroxy pyrrolidine derivatives
09/04/2001US6284492 Recombinant animal viral nucleic acids
08/2001
08/30/2001WO2001062948A2 Method and catalyst system for stereoselectively inverting a chiral center of a chemical compound
08/30/2001US20010018529 Chemical intermediate for antidiabetic drug
08/30/2001US20010018205 Process for stereospecific hydrolysis of piperidinedione derivatives
08/30/2001US20010018201 Using hapten
08/29/2001EP1127872A1 Tamiflu via Diels-Alder
08/29/2001CN1310170A Process for producing 4,5-diamino shikimic acid derivative
08/29/2001CA2338308A1 Microbial process for preparation of optically active 3-hydroxypyrrolidine derivatives
08/28/2001US6281003 Enzymatic synthesis of optically active hydroxamic acids and their conversion to optically active primary amines by a lossen rearrangement
08/23/2001WO2001061027A1 Processes for producing optically active 1,2-epoxy-2,6,6-trimethylcyclohexane methanol
08/21/2001US6277626 Lactam esters are contacted with a biocatalyst, such as enzyme or a microorganism, in solution wherein only one enantiomer is selectively hydrolyzed to give optically active isomer of corresponding acid; separating hydrolysis product
08/16/2001WO2001058894A1 Stereoselective synthesis of nucleoside analogues
08/16/2001EP1123410A1 The enzyme-mediated synthesis of peptidomimetics
08/16/2001EP1123386A1 Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase
08/16/2001EP0731843B1 Tyrosinase-activator protein fusion enzyme
08/09/2001WO2001057232A1 Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives
08/09/2001US20010012898 Optically purity; from alkenyl ester
08/09/2001DE10006824A1 Verfahren zur kinetischen Racematspaltung von Carbonsäureestern A method for kinetic resolution of carboxylic acid esters
08/09/2001DE10004926A1 Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten A process for the enzymatic resolution of aminomethyl-aryl-cyclohexanol derivatives
08/08/2001EP1121446A1 Aminoacylase and its use in the production of d-aminoacids
08/08/2001EP0951561B1 Enzymatic processes for preparing (s)-cyanohydrins
08/07/2001US6271005 By stereospecific acylation by the enzyme pseudomonas cepacia lipase of one stereoisomer while leaving the other unchanged; 5-methoxy-2-aminotetralin chemical intermediates to a 2-aminotetralin-ethylthiophene parkinson's drug
08/01/2001EP1120465A1 D-Aminoacylase and gene encoding the same
08/01/2001EP1120397A2 Process for preparing triazole derivative
08/01/2001EP1119635A1 Non-homogeneous systems for the resolution of enantiomeric mixtures
08/01/2001EP1119634A1 Enzyme-catalyzed racemic cleavage of primary amines
07/2001
07/31/2001US6268207 Resolution of enantiomers from a mixture of (1r,2s)/(1s,2s)-1-amino-2-vinylcyclopropyl carboxylic acid methyl ester comprising the step of treating said mixture with an esterase to obtain the corresponding (1r,2s) enantiomer
07/31/2001US6268185 Production of amino acids and enzymes used therefor
07/26/2001US20010009770 Process for the preparation of prostaglandin precursors
07/25/2001EP1118674A1 Process for producing optically active tropinone monocarboxylic acid derivative
07/25/2001EP1117823A1 Resolution of trans-2 -(alkoxycarbonylethyl) -lactams useful in the synthesis of 1- (4-fluorophenyl) -3(r) - 3(s) -hydroxy-3 -(4-fluorophenyl) -propyl)] -4(s) -(4-hydroxyphenyl) -2-azetidinone
07/25/2001EP0704419B1 Process for producing an optically active 2-aryl-3-acyloxy-1,2-propanediol
07/18/2001EP1116795A1 Process for producing optically active pyridineethanol derivatives
07/18/2001EP1115881A1 Process for the enzymatic kinetic resolution of 3-phenylglycidates by transesterification with aminoalcohols
07/18/2001EP0876329B1 Process for the production of n-acetyl-d,l-alpha-aminocarboxylic acids
07/17/2001US6262295 Process for the preparation of a racemic or optically active 4-(hydroxymethyl)-2-cyclopentene derivative
07/17/2001US6261830 Enzymatic process for stereoselective preparation of a tertiary acid
07/11/2001EP1114815A2 Process to prepare taxol
07/11/2001CN1302612A Preparation method of medicinal composition containing 1,3-oxathin cyclopentane nucleoside analogues
07/10/2001US6258574 Stereospecifically esterifying a racemic mixture of cis-substituted tetrahydropyran-4-ol using esterase
07/05/2001WO2001048175A2 METHODS FOR PRODUCING ENANTIOMERICALLY PURE α-SUBSTITUTED CARBOXYLIC ACIDS
07/05/2001US20010006797 Transfection cell with genetic vector
07/05/2001CA2365224A1 Methods for producing enantiomerically pure .alpha.-substituted carboxylic acids
07/03/2001US6255325 Chronic, bolus administration of D-threo methylphenidate
07/03/2001US6255092 Stereospecific alcohol dehydrogenase isolated from Candida parapsilosis, amino acid and DNA sequences therefor, and method of preparation thereof
06/2001
06/27/2001EP0759066B1 Process for obtaining micro-organisms containing peptide amidase, micro-organisms obtained therewith, peptide amidases contained in them and use thereof
06/27/2001CN1301310A Method for producing hydroxycarboxylic acids by auto-degradation of polyhydroxyalkanoates
06/26/2001US6252112 Process for the preparation of an enantiomer of a (1R, 4S) or (1S, 4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene derivative
06/26/2001US6251650 Pseudomonas putida amidase polypeptide useful for the production of chiral amides and acids
06/21/2001WO2001044492A2 Method for kinetic resolution of racemates of alcohols or carboxylic acid esters
06/21/2001WO2001044487A1 Method for the production of optically active cyanohydrins using r-oxynitrilase
06/21/2001WO2001029245A3 ENZYMATIC PROCESS FOR THE RESOLUTION OF ENANTIOMERIC MIXTURES OF β-LACTAMS
06/21/2001DE19963315A1 Resolution of racemic alcohols and carboxylic acid esters involves lipase catalyzed labeling of one enantiomer with fluorine to improve enantiomer separation procedure
06/21/2001DE19963314A1 Resolution of racemic alcohols and carboxylic acid esters involves lipase catalyzed labeling of one enantiomer with fluorine to improve enantiomer separation procedure
06/21/2001CA2393080A1 Method for the production of optically active cyanohydrins using r-oxynitrilase
06/20/2001EP1108053A1 Method for preparing (2r)-piperidine derivatives
06/14/2001WO2001042251A1 Vitamin d precursors, method and intermediates
06/13/2001EP1106618A1 Precursors of the A-ring of vitamin D, and method and intermediates for the preparation thereof
06/13/2001EP1105416A1 Novel process for the synthesis of exochelins
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