Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
01/2001
01/30/2001US6180374 Method for preparing tert-leucine and analogues thereof in enantiomeric form and intermediates therein
01/25/2001WO2001005996A1 Process for producing optically active pyridineethanol derivatives
01/25/2001WO2001005982A1 Method for the production of l-amino acids from their racemic n-acetyl-d, l-derivatives by enzymatic racemate cleavage by means of isolated recombinant enzymes
01/25/2001CA2379849A1 Process for the preparation of l-amino acids from their racemic n-acetyl-d,l derivatives by enzymatic resolution by means of isolated, recombinant enzymes
01/25/2001CA2343970A1 Process for producing optically active pyridineethanol derivatives
01/24/2001EP1070132A2 RECOMBINANT L-N-CARBAMOYLASE DERIVED FROM $i(ARTHROBACTER AURESCENS), AND A METHOD FOR PRODUCING L-AMINO ACIDS BY USING THE SAME
01/24/2001EP0812363B1 Process for preparing optically active amines
01/23/2001US6177573 Process to prepare taxol
01/18/2001WO2001004336A1 Method of reducing keto-carboxylic acids and their esters
01/18/2001DE19937825A1 Verfahren zur Reduktion von Keto-Carbonsäuren und deren Estern A process for the reduction of keto-carboxylic acids and esters thereof
01/17/2001EP1069183A2 Immobilized lipase
01/17/2001EP1069109A1 Process for production of optically active N-protected-N-methyl-phenylalanine derivative
01/17/2001CN1280189A 固定化脂酶 Immobilized lipase
01/16/2001US6174711 Method for producing L-allysine acetal
01/16/2001US6174707 Converting d,l-allysine acetal to mixture of 2-oxo-6,6-dialkoxyhexanoic acid and l-allylsine by reacting in the presence of an enzyme capable of stereoselective oxidative deamination of d-amino acids, isolating l-allylsine
01/16/2001CA2089626C Process for separating 1,2-isopropylideneglycerol benzoyl ester enantiomers
01/11/2001DE19931847A1 Immobilisierte Lipase Immobilized lipase
01/09/2001CA2313374A1 Immobilized lipase
01/02/2001CA2161662C Process for preparing intermediates for the synthesis of antifungal agent
12/2000
12/28/2000DE19929577A1 Yeast alpha-oxidation enzymes, used to degrade organic compounds by one carbon atom, used to convert 5-hydroxydecanoic acid to gamma-nonalactone
12/27/2000EP1062950A2 1,3 Oxathiolane nucleoside analogues
12/27/2000CN1059898C Piperidine derivatives, prepn. method and use thereof
12/26/2000US6165777 Resolution of enantiomers of cis-1,2-dihydroxyindan compound of given formula by treating with p. putida to allow destruction of the 1r,2s-enantiomer and recovering the 1s,2r enantiomer; chemical intermediates to drugs, agrochemicals
12/19/2000US6162621 Process for producing optically active azetidine-2-carboxylic acid derivative
12/05/2000US6156893 Process for the preparation of (1S,4R)- or (1R,4S)- 4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol
11/2000
11/29/2000EP1055732A1 Process for producing (r)-2-hydroxy-1-phenoxypropane derivative
11/29/2000EP1054996A1 Process for the enzymatic resolution of lactams
11/28/2000US6153751 Preparing the antiviral b-isomer of a 1,3-oxathiolane nucleoside by reacting in presence of stannic chloride
11/28/2000US6153414 Method for racemic biochemical resolution of CIS-and trans-pyprolopiperidine
11/28/2000CA2074681C Genetic engineering process for the production of s-(+)-2,2-dimethylcyclopropanecarboxamide by microorganisms
11/22/2000EP1053258A1 Device for producing polymer support materials in the form of porous polymer beads
11/16/2000WO2000068394A1 Epoxide hydrolases of aspergillus origin
11/15/2000EP1051480A2 Enzyme activated supports for enantiomeric separations
11/15/2000EP0832191A4 Recombinant viral nucleic acids
11/15/2000CN1273608A Process for preparing (2R, 3S)-3-(4-lower alkoxyphenyl) glycidic acid esters
11/14/2000US6146879 Spray drying whole cells of fusarium lateritium containing cyanide hydratase, methylophilus methylotrophus containing amidase and pseudomonas putida containing d-2-haloalkanoic acid halidohydrolase; enzymes retain activity
11/07/2000US6143933 Process for the preparation of optically active methadones in high enantiomeric purity
11/07/2000US6143554 Process for producing optically active n-substituted azetidine-2 carboxylic acid compound
11/07/2000US6143541 Gene encoding a protein having symmetric hydrolase activity for 4-substituted 1,4-dihydropyridine derivatives and its expression product
10/2000
10/31/2000US6140088 With an amino acid dehydrogenase in the presence of ammonia and a co-factor
10/26/2000DE19857302C2 Verfahren zur enantioselektiven Reduktion von 3,5-Dioxocarbonsäuren, deren Salze und Ester A process for the enantioselective reduction of 3,5-Dioxocarbonsäuren, its salts and esters
10/25/2000EP1046712A2 Method of resolving 2-oxobicyclo (3.1.0) hexane-6-carboxylic acid derivatives
10/24/2000US6137007 Enantiomer compositions of (1R,4S)-1-butyrylamino-4-(hydroxymethyl)-2-cyclopentene
10/24/2000US6136591 Contacting a racemic n-acylazetidine-2-carboxylic acid ester with an enantiospecific enzyme to form enantiomerically enriched n-acylazetidine-2-carboxylic acid, an intermediate to azetidine-2-carboxylic acid and proline synthesis
10/19/2000WO2000061777A1 Process for the preparation of prostaglandin precursors
10/19/2000WO2000061734A2 Enzyme compositions and their use as catalysts
10/18/2000EP1045029A2 Process for producing optically active 4-hydroxy-2-ketoglutaric acids
10/18/2000EP1045025A1 (S)-alpha-PHENETHYLAMINE : PYRUVATE TRANSAMINASE
10/18/2000CN1057568C Process for preparation of D-alpha-amino acids
10/17/2000US6133421 Polypeptides and polypeptide subunits of a stereospecific nitrile hydratase enzyme
10/17/2000US6133018 Enzymatic synthesis of chiral amines using -2-amino propane as amine donor
10/17/2000US6133002 Acetalization of dialdehyde with alcohol, diol, or orthoformic ester; amination, cyanation, oxidation; enantioselective hydrolysis
10/11/2000EP1043401A1 Methods for producing optically active amino acids
10/11/2000CN1269406A Levo-diketoreductase
10/05/2000WO2000058500A1 THE PREPARATION OF trans-4-AMINO-2-CYCLOPENTENE-1-CARBOXYLIC ACID DERIVATIVES
10/05/2000WO2000058449A1 Hydantoinase variants with improved properties and their use for the production of amino acids
10/05/2000WO2000058283A1 Biocatalyst and its use in enzymatic resolution of racemic beta-lactams
10/05/2000DE19913862A1 Biotransformation of compound with poor solubility in water, especially terfenadine, involves reaction in aqueous medium in bioreactor and in situ substrate and product separation
10/05/2000CA2360944A1 Biocatalyst and its use in enzymatic resolution of racemic beta-lactams
10/05/2000CA2303697A1 An optical resolution of 4-halogeno-3-alkanoyloxybutyronitrile
10/04/2000CN1057089C Process for preparing intermediates for synthesis of antifungal agents
09/2000
09/27/2000EP1038953A1 Stereoselective transaminase, gene encoding said protein and use thereof
09/21/2000WO2000039324A3 Method for producing optically active 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives
09/20/2000EP1036190A1 A method for producing hydroxycarboxylic acids by auto-degradation of polyhydroxyalkanoates
09/20/2000EP1036189A1 Resolution of chiral amines
09/20/2000EP0580667B1 Enantiomers of cyclopentene derivatives
09/20/2000CN1267334A Method for racemic biochemical resolusion of cis- and trans-pyrrolopiperidine
09/20/2000CN1266904A Process for preparing stereoisomer carboxylate
09/19/2000US6121025 Process for producing optically active 3-quinuclidinol derivatives
09/06/2000EP1032389A1 CHRONIC, BOLUS ADMINISTRATION OF D-threo METHYLPHENIDATE
09/06/2000CN1056145C Prepn. of 1,3-oxathiolane nucleoside analogue medicine composition
09/05/2000US6114582 Processes for producing optically active 2-amino-1-phenylethanol derivatives
09/05/2000US6114343 Antiviral activity and resolution of 2-hydroxymethyl-5-(5-flurocytosin-1-yl)-1,3-oxathiolane
09/05/2000US6114163 Process for obtaining active L-α-amino carboxylic acids from corresponding racemic d, L-α-amino carboxylic acids
08/2000
08/31/2000WO2000050628A1 Enantioselective enzymatic hydrolysis of 3-substituted esters of glutaric acid
08/31/2000WO2000050623A2 Method for preparing optically active 3,3,3-trifluoromethyl-2-alkyl propionic acid derivatives
08/31/2000DE19908074A1 Verfahren zur Herstellung von stereoisomeren Carbonsäureestern A process for the production of stereoisomeric carboxylic acid esters
08/30/2000EP1031629A2 Method of preparation of stereoisomeric carboxylic acid esters
08/29/2000US6110729 Treating racemic compound with a stereoselective hydrolase and isolating product; for cellular potassium channel openers useful in treatment of urinary inconteinence, hypertension, asthma, peripheral vascular disease, and angina
08/23/2000EP1029071A1 Process for preparing (2r,3s)-3-(4-lower alkoxyphenyl)glycidic acid esters
08/22/2000CA2042421C A method for the preparation in a non-racemic form of furo (3,4-c) pyridine derivatives
08/17/2000WO2000047759A1 Stereoselective synthesis of nucleoside analogues
08/17/2000CA2362570A1 Stereoselective synthesis of nucleoside analogues
08/15/2000US6103517 Process for the production of an optically active alcohol and a novel optically active alcohol
08/10/2000WO2000037619A3 Mutant epoxide hydrolases
08/09/2000EP1026235A1 Levodione reductase
08/09/2000CN1262330A Process for preparing cyclopropanecarboxylic acid with optical active
08/01/2000CA2297440A1 Levodione reductase
08/01/2000CA2009296C N-acyl-2-amino acid amides containing phosphinic esters, process for their preparation, and n-acyl-2-amino acid nitriles as precursors
08/01/2000CA2009295C Process for the enzymatic resolution of 2-amino-4-methylphosphinobutyric acid derivatives
07/2000
07/27/2000WO2000043532A1 Method for carrying out enzyme reactions by simultaneous enzymatic reaction and chromatography, notably for the separation of optical isomers
07/27/2000WO2000043357A1 Method for purifying and isolating (2s,3s)- or (2r,3s)-halohydrin derivatives
07/27/2000WO2000028007A3 Chemically modified mutant serine hydrolases
07/27/2000DE19901925A1 Reactive separation of optical isomers comprises passing the isomers over a hydrolase enzyme immobilized on a microporous solid
07/26/2000CN1261405A Process for preparing enantiomerically enriched N-derivatised lactams
07/26/2000CN1054882C Enzymatic process for the stereoselective preparation of a hetero-bicyclic alcohol enantiomer
07/19/2000EP1020458A1 Optically active 1,4-benzodioxine-2-carboxylic acid derivatives and process for producing the same
07/18/2000US6090616 Stereospecific hydrolysis of a mixture of enantiomers; incubating mixture with an enzyme capable of hydrolysing an enantiomer
07/12/2000CN1259577A Micro-organism biotransformation method
07/11/2000US6087145 Esterase gene and its use
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