Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
04/1993
04/01/1993CA2118796A1 Pyranones
04/01/1993CA2118795A1 Pyranones
03/1993
03/31/1993EP0264457B1 Process for preparing optically active cyclopropanecarboxylic acids
03/30/1993US5198568 Improved resolution of enantiomorphs by forming water soluble derivatives, ibuprofen derivatives
03/25/1993DE4131546A1 Candida lipase for high activity and aldehyde resistance - comprises covalent bonding to epoxy activated macroporous carrier for immobilisation and enantioselective esterification of chiral alcohol with enol ester
03/24/1993CN1070191A 1,3-oxathiolane nucleoside analogues
03/23/1993US5196568 Compounds useful in enzymatic resolution systems and their preparation
03/09/1993US5192687 Oxidoreductase capable of reverse oxidation
03/09/1993CA1314254C Enzymatic membrane method for the synthesis and separation of peptides
03/04/1993WO1993004190A1 Arylalkanoic acid resolution
03/04/1993WO1993004189A1 Arylalkanoic acid resolution
03/04/1993WO1993004058A1 Chiral glutarate esters, their resolution and derived glutarimide compounds
03/04/1993WO1992018444A3 Cyclopentenes
03/04/1993CA2116108A1 Chiral gultarate esters, their resolution and derived glutarimide compounds
03/04/1993CA2116004A1 Arylalkanoic acid resolution
03/03/1993EP0529601A1 Process for the production of optically active vinylglycine in free or protected form by an enzymatic, anantioselective hydrolysis
03/03/1993EP0529590A1 Intermediates for D-biotin synthesis and their production
03/03/1993EP0529483A2 Process for the preparation of optically active 4-amino-3-hydroxycarboxylic acids
03/03/1993EP0529424A2 Process to increase the enantiomeric selectivity of a lipase from Candida by esterification of chiral alcohols and immobilized lipase
03/03/1993EP0529085A1 Process for producing optically active 3-chloro-1-phenyl-1-propanol and derivative thereof
03/02/1993US5191109 Prostaglandin intermediates
03/02/1993US5190867 Process for the preparation of R-2,2-R1,R2 -1,3-dioxolane-4-methanol
03/01/1993CA2075699A1 Process for increasing the enantio-selectivity of a candida lipase in the esterification of chiral alcohols, and an immobilized candida lipase
02/1993
02/28/1993CA2076902A1 Intermediates for d-biotin synthesis and their production
02/24/1993EP0528607A2 Process for preparing optically active 3-phenylglycidic acid esters
02/24/1993EP0528256A1 D-2,4-dihydroxy-3,3-dimethylbutyronitrile, its production and use and process for production of D-pantolactone, D-2,4-dihydroxy-3,3-dimethylbutyramide and D-pantothenic acid
02/23/1993CA2076580A1 Process for the production of optically-active 4-amino-3-hydroxycarboxylic acids
02/18/1993WO1993003027A1 1,3-oxathiolane nucleoside analogues
02/17/1993EP0527553A1 Process for producing r(-)-mandelic acid and derivative thereof
02/16/1993US5187094 Using Pseudomonas or Mucor stereospecific esterases for hydrolysis of racemic mixtures of N-benzyl-3-acyloxy-pyrrolidine
02/04/1993WO1993002207A1 Stereoselective synthesis of alcohols
02/04/1993WO1993002034A1 Process for enzymatically preparing enantiomer-free esters and alcohols
02/04/1993CA2111711A1 Process for enzymatically preparing enantiomer-free esters and alcohols
02/03/1993EP0526253A1 1,3-Oxathiolane nucleoside analogues
01/1993
01/27/1993EP0524604A2 Process for the preparations of S-(+)-2,2-dimethyl-cyclopropane carboxamid by genetically engineered microorganismes
01/26/1993US5182209 Enantioselective preparation of s-2R1,2R2 -1,3-dioxolane-4-methanol and derivatives thereof
01/26/1993US5182198 Process for preparing (+)-homopilopic acid
01/21/1993DE4123253A1 Racemic ester(s) of halogenated aryl-alkanol(s) - can be enzymically hydrolysed to give pure (R)-alcohol and pure (S)-ester which can then be further reacted to tomoxetine, fluoxetine, nisoxetine etc.
01/19/1993US5180671 Method for producing optically active cyclopropane carboxylic acid
01/05/1993US5177007 Process for producing optically active r-(+)-2,3-dichloro-1-propanol using microorganism
01/05/1993US5177006 Enzyme inhibitors
12/1992
12/29/1992US5175100 Using enzymes derived from certain animals
12/16/1992EP0517798A1 Stereospecific resolution by hydrolysis of esters of 2-arylpropionic acids by liver enzymes.
12/14/1992WO1992001062A1 Process for producing enantiomers of 2-aryl-alkanoic acids
12/08/1992US5169780 Conversion to ketone in aqueous solution with amino acceptor and omega-amino acid acceptor; solvent extraction
12/08/1992US5169779 Enzyme catalyzing the transesterification of dextrorotatory enantiomer into insoluble form by adding acid, salt or ester derivative of butanol
12/03/1992DE4117255A1 Enzymatic hydrolysis of carboxylic acid derivs. - by forming a soln. of the acid deriv. in an organic solvent with only slight water miscibility, saturating the soln. with water and contacting with a hydrolase
12/02/1992EP0515698A1 PROCESS FOR PRODUCING D-$g(a)-AMINO ACID
12/02/1992EP0515541A1 METHOD FOR PREPARING CIS--g(b)-PHENYLGLYCIDIC-(2R,3R) ACID.
11/1992
11/26/1992WO1992020812A1 Process for producing chiral compounds as pure optical isomers
11/25/1992EP0514780A2 Process for the preparation of linear enantiomer-pure N-alkyl-L or D-amino acids
11/24/1992US5166062 Methods for separating diol and triol stereoisomers from a stereoisomer mixture
11/19/1992EP0513806A1 Esterase genes, esterase, recombinant plasmids and transformants containing the recombinant plasmid and methods of producing optically active carboxylic acids and their enantiomeric esters using said transformants
11/19/1992EP0513200A1 Method and compositions for the synthesis of bch-189 and related compounds
11/11/1992EP0512848A2 Enzymatic resolution of alpha-tertiary carboxylic acid esters
11/11/1992EP0330695B1 Process for preparation of organic chemicals
11/09/1992CA2068038A1 Enzymatic resolution of .alpha.-tertiary carboxylic acid esters
11/04/1992EP0511526A1 Process for enzymatic hydrolysis of a carboxylic acid derivate
11/03/1992CA1309683C Process for preparing l(-)-carnitine chloride from 3, 4-epoxybutyric esters and novel intermediate compounds
10/1992
10/30/1992CA2065550A1 Process for the enzymatic hydrolysis of a carboxylic acid derivative
10/29/1992WO1992018477A1 Azabicycloheptanone
10/29/1992WO1992018444A2 Cyclopentenes
10/29/1992WO1992014743A3 Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane
10/28/1992EP0510712A2 Process for the separation of the optical isomers of alpha-substituted carboxylic acids
10/27/1992CA2066926A1 Process for the separation of the optical isomers of alphasubstituted carboxylic acids
10/20/1992US5156965 Monoclonal antibodies
10/20/1992CA1309048C Process for preparing l(-)-carnitine chloride
10/13/1992US5155043 Method for preparing optically active substances
10/13/1992US5155030 Process for preparing optically active (R)-(-)-3-halo-1,2-propanediol from an epihalohydrin by a strain of corynebacterium or microbacterium
10/13/1992US5155028 Incubation, enyzmatic hydrolysis; stereoselective; antiinflammatory agents
10/07/1992EP0507278A2 Immobilised biocatalyser, its preparation and use for ester synthesis in a column reactor
10/07/1992EP0507153A2 Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenyl-propionic acids
10/07/1992CN1065065A Process for preparing 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane
10/03/1992CA2064676A1 Immobilized biocatalyst, its preparation and use for ester synthesis in a column reactor
10/01/1992WO1992016636A1 Recombinant virus vectors encoding human papillomavirus proteins
10/01/1992CA2106069A1 Recombinant virus vectors encoding human papillomavirus proteins
09/1992
09/30/1992EP0505567A1 Process for producing optically active 1,3-butanediol
09/30/1992CN1064892A Recombinant virus vectors
09/23/1992EP0504421A1 D-pantolactone hydrolase and production thereof
09/09/1992EP0502525A1 Biotechnological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide and R-(-)-2,2-dimethylcyclopropanecarboxylic acid
09/03/1992WO1992014835A1 Process for producing optically active 3-chloro-1-phenyl-1-propanol and derivative thereof
09/03/1992WO1992014743A2 Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane
09/02/1992EP0501353A2 Process for producing optically active 2-hydroxycycloalkanecarboxylic acid esters
09/02/1992EP0501310A1 Method for optical resolution of corey lactone diols
09/02/1992EP0501292A1 A L-carnitine-amidase producing microorganism, L-carnitine-amidase, method of production and use
09/01/1992US5143831 Fructose 1,6-diphosphate aldolase catalyzed steroselective synthesis of sugars
08/1992
08/26/1992WO1992014693A1 Method of preparation of pilocarpines and intermediates thereof
08/26/1992EP0500364A1 Optically active 1,3-dioxin-4-ones
08/26/1992CA2101445A1 Method of preparation of pilocarpines and intermediates thereof
08/12/1992EP0498706A1 Process for the preparation of (-)-(2R,3S)-2,3-epoxy-3-(4-methoxyphenyl)methylpropionate
08/05/1992EP0497103A2 Gene encoding asymmetrically active esterase
08/05/1992CN1063310A Process for preparation of d-alpha-amino acids
08/01/1992WO1992013843A1 Synthesis of intermediates in the preparation of acat inhibitors
08/01/1992CA2099564A1 Synthesis of intermediates in the preparation of acat inhibitors
07/1992
07/29/1992EP0496001A1 Process for producing optically active 3-phenyl-1,3-propanediol
07/16/1992DE4100394A1 Prepn. of optically active alcohol(s) and optically active ester(s) - by enantioselective acylation of racemic alcohol(s) with vinyl ester(s) of higher fatty acids in the presence of a lipase
07/15/1992EP0494716A2 Enzyme-catalysed preparation of optically active carboxylic acids
07/14/1992US5130252 Esterification and enzymatic hydrolysis to form the enantiomer
07/14/1992US5130240 Process for producing d-alpha-alanine and/or l-alpha-alanineamide by arthrobacter sp
07/12/1992CA2059075A1 Enzyme-catalysed preparation of optically active carboxylic acids
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