Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
07/1992
07/07/1992US5128264 Process for preparing optically active 3-hydroxybutane derivatives using lipase
07/07/1992US5128263 Producing captopril
07/07/1992US5128252 Resolution of optically active esters, transesterification, lipase
07/01/1992EP0493060A2 Production method of d-pantothenic acid and plasmids and microorganisms thereof
06/1992
06/25/1992WO1992010579A1 PROCESS FOR PRODUCING D-α-AMINO ACID
06/24/1992EP0491548A2 Processes and intermediates for thromboxane receptor antagonists
06/19/1992CA2055572A1 Processes and intermediates for thromboxane receptor antagonists
06/17/1992EP0490407A2 Process for the enzymatic separation of the optical isomers of tosyloxy-alkanols
06/16/1992US5122462 Reacting oxo compound with hydrocyanic acid in presence of oxynitrilase solubilized in lyotropic liquid crystal under acid conditions
06/10/1992EP0489323A1 Optically pure dithiolanyl- and dithianoamino acids and their derivatives, process for their preparation and their use
06/09/1992US5120652 Substantially purified n-acyl-l-proline acylase from comamonas testosteroni dsm 5416 and alcaligenes denitrificans dsm 5417
06/03/1992EP0488999A1 A method for producing optically active cyclopropane carboxylic acid
06/03/1992EP0488916A1 Process for enzymatic preparation of ammonium adipate
06/02/1992US5118619 Culturing corynebacterium or brevibacterium under aerobic condition in aqueous culture medium
05/1992
05/29/1992CA2056326A1 Enzymic process for the synthesis of ammonium adipate
05/27/1992DE4037251A1 Prepn. of optically active alpha-hydroxy:carboxylic and alpha-acetoxy:carboxylic acid - by acylation of racemate of alpha-hydroxy:carboxylic acid with vinyl carboxylate, using lipase in organic solvent
05/20/1992EP0486289A2 Biological process for producing alpha-hydroxyamide or alpha-hydroxy acid
05/20/1992EP0440723A4 Process for preparing optically active glycidate esters
05/19/1992CA1301100C Resolution of racemates of 3-acyloxy- bicyclo-[3.3.0]-octane-7-one-2-carboxylic acid esters by stereo-specific enzymatic or microbiological acylate hydrolysis
05/06/1992EP0484063A2 Process for preparing optically active epoxy alcohols
05/05/1992US5110943 Certain phenoxy (or 5-trifluoromethyl-pyridyl-oxy)-phenoxy-2-yl-propane derivatives
04/1992
04/30/1992WO1992007082A1 Process for producing optically active 1,3-butanediol
04/28/1992US5108917 Process for the preparation of ibuprofen
04/28/1992US5108916 Process for stereoselectively hydrolyzing, transesterifying or esterifying with immobilized isozyme of lipase from candida rugosa
04/21/1992US5107039 Intermediates for asymmetric synthesis of steroids and alkaloids
04/21/1992US5106750 Enantio- and regioselective synthesis of organic compounds using enol esters as irreversible transacylation reagents
04/21/1992US5106736 Enzymatic process for enantiomer-specific perparation of mercapto alkanoic acid compounds
04/16/1992WO1992006182A1 D-pantolactone hydrolase and production thereof
04/15/1992EP0480676A2 Acyl carnitine esterase, production thereof and method for analyzing acyl carnitines
04/15/1992EP0480567A1 Selective aqueous extraction of organics coupled with trapping by membrane separation
04/15/1992EP0423133A4 Enzymatic resolution systems and compounds useful in the systems and their reparations
04/14/1992CA1298800C Immobilized enzyme preparation and its use
04/10/1992CA2046552A1 Selective aqueous extraction of organics coupled with trapping by membrane separation
04/07/1992US5102799 Of esters
04/07/1992US5102793 Treating with a culture product to form optically active 3alpha-hydroxy prostacyclin compound
04/02/1992WO1992005275A1 A process for the preparation of enantiomeric 2-alkanoic acids
03/1992
03/18/1992EP0475255A2 Process for the preparation of optically pure (S)-alpha-[(tert-butylsulfonyl)methyl]hydro cinnamic acid
03/18/1992EP0474861A1 Alcohol-ester separation by reaction with acetate.
03/11/1992EP0474250A2 Enzymatic process for separating the optical isomers of racemic 1,2-diols
03/11/1992EP0474129A2 1,4-Dihydropyridine derivatives and process for preparing the same
03/04/1992EP0473328A2 Biological process for preparing optically active lactic acid
03/03/1992US5093250 Process for producing optically active bicyclo[3.3.0]octanedione carboxylic acid esters
02/1992
02/26/1992EP0472336A1 Process for preparing optically active 3-hydroxybutane derivatives
02/20/1992WO1992002631A1 Process for producing optically active 3-phenyl-1,3-propanediol
02/19/1992EP0471531A1 Process for preparing optically active alpha-hydroxyalkene derivatives
02/18/1992US5089637 2R-(trifluoromethylsulfonyloxymethyl) chroman or 2R-benzylchroman
02/18/1992US5089405 Process for the preparation of optically active 2-arylpropionic acids and pharmaceutical compositions containing the same
02/18/1992US5089176 2-acyloxymethyl-3-hydroxymethylbicyclo (2.2.2)oct-5-ene
01/1992
01/29/1992CN1058214A 1,3-oxathiolane nucleoside analogues
01/28/1992US5084392 Process for producing optically active hydroxy lactones
01/28/1992US5084387 Microbiological hydrolysis for the preparation of (exo,exo)-7-oxabicyclo(2.2.1) heptane-2,3, monoacyl ester dimethanol
01/28/1992CA1294910C Process for the enzymatic separation of the optical isomers of racemic oxazolidinonic derivatives
01/22/1992EP0467132A2 4-Substituted-2-hydroxybutanoates and a process for producing them
01/14/1992US5081024 Resolution by microbial fermentation
01/08/1992EP0464905A1 Enzymatic, enantioselective preparation of R-glycidol
01/07/1992US5079167 Enzymatic resolution of amino acid carbamate racemates
01/07/1992US5079152 Antibody combining sites that exhibit stereoselective synthase activity, and methods using the same
01/06/1992CA2086236A1 Process for producing enantiomers of 2-aryl-alkanoic acids
12/1991
12/31/1991US5077217 Using enzymes in aqueous solutions
12/24/1991US5075233 Process for the preparation of 2-aryloxypropionic acids
12/12/1991WO1991019002A1 A process for chiral enrichment of asymmetric primary amines
12/11/1991EP0461043A2 Enantiomer separation by transesterification
12/11/1991EP0460949A2 Enantiomerically selective enzymic acylation of a racemic 3-amino azetidinone
12/04/1991EP0459455A2 Process for producing optically active alpha-hydroxyesters
12/03/1991US5070022 Lipase from pseudomonas, candida or chromobacterium
11/1991
11/26/1991US5068187 Process for producing D-α-amino acids
11/26/1991CA1292434C Process for racemizing an optically active n-benzylidene amino-acid amide
11/14/1991WO1991017159A1 1,3-oxathiolane nucleoside analogues
11/14/1991CA2337748A1 1,3-oxathiolane nucleoside analogues
11/13/1991EP0456107A2 Process for the enzymatic reduction of oxo-compounds, especially acetophenone and the enzyme therefor
10/1991
10/30/1991EP0454463A2 Process for producing epoxyalcohols of high optical purity
10/29/1991US5061629 Pseudomonas lipase
10/27/1991CA2039857A1 Process for producing epoxyalcohols of high optical purity
10/17/1991WO1991013066A3 METHOD FOR PREPARING CIS-β-PHENYLGLYCIDIC-(2R,3R) ACID
10/16/1991EP0451668A2 Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof
10/15/1991US5057607 3-amino-2(ethyl-2-furanyl)-4-oxo azetidine acetic acids or esters are reacted with substituted acids or esters in presence of penicillin G amidase
10/15/1991US5057427 Method for resolution of stereoisomers
10/02/1991EP0449648A2 Process for producing R(-)-mandelic acid and derivatives thereof
10/02/1991DE4009891A1 Prepn. of optically active alcohol(s) and carbonic acid di:ester(s) - by hydrolysis of racemic carbonic acid di:ester(s) with lipase
10/01/1991WO1991015470A1 Alcohol-ester separation by reaction with acetate
10/01/1991US5053507 Optically active pyrimidines derivatives
09/1991
09/25/1991EP0448254A2 Process and intermediates for 2R-benzyl-chroman-6-carbaldehyde
09/25/1991EP0447938A1 Process for preparing 2-halogeno-3-hydroxy-3-phenyl-propionic acid ester compounds
09/25/1991EP0431060A4 Method of catalyzing stereochemical reactions
09/24/1991US5051525 Selective hydrolysis of nitriles to form amides
09/18/1991EP0446826A2 Process for the production of optical active cyanhydrin
09/18/1991EP0446771A2 Esterase from Serratia and process for preparing the same
09/18/1991EP0148272B1 Process for producing optically active benzyl alcohol compounds
09/17/1991US5049497 Novel process for the synthesis of the enantiomers of bicyclo(4.2.0)oct-2-en-7-one and derivatives
09/10/1991US5047585 Process for racemizing an optically active N-benzylidene amino-acid amide
09/10/1991US5047346 Optically active 3-(2-trifluoro-1-hydroxyethyl)propenyl benzyl ether, derivatives thereof, method for preparing the same and use thereof for liquid crystal compound
09/05/1991WO1991013066A2 METHOD FOR PREPARING CIS-β-PHENYLGLYCIDIC-(2R,3R) ACID
08/1991
08/28/1991EP0443406A2 Process for enzymatic racemate separation of pantolacton
08/27/1991WO1991013163A1 Stereospecific resolution by hydrolysis of esters of 2-arylpropionic acids by liver enzymes
08/27/1991US5043274 Microorganism containing stereospecific inverting enzyme
08/27/1991CA2076972A1 Stereospecific resolution by hydrolysis of esters of 2-arylpropionic acids by liver enzymes
08/22/1991WO1991012221A1 Process for separating enantiomeric substances, and a separating medium for carrying out the process
08/20/1991US5041375 Method of producing carnitine
08/20/1991US5041227 Continous recycling of extractant
08/14/1991EP0440723A1 Process for preparing optically active glycidate esters.
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