Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
12/1993
12/02/1993DE4217506A1 Mikrobielle Esterase zur enantioselektiven Spaltung von 1-Arylalkylestern Microbial esterase for the enantioselective cleavage of 1-arylalkyl esters
11/1993
11/30/1993US5266710 (Exo,exo)-7-oxabicyclo[2.2.1]heptane-2,3-dimethanol; monoacyl ester and diacyl ester
11/25/1993WO1993023547A1 ENZYMATIC PROCESS FOR PRODUCTION OF S-6-METHOXY-α-METHYL-2-NAPHTHALENEACETIC ACID
11/24/1993EP0570593A1 Process for producing optically active norborneol
11/16/1993US5262571 Ionization, salt formation, decyclization and esterification
11/11/1993WO1993022451A1 PROCESS OF PREPARING ENRICHED ENANTIOMERS OF GLYCEROL CARBONATE AND DERIVATIVES THEREOF FOR SYNTHESIS OF β-BLOCKERS
11/11/1993WO1993022284A1 Process for stereospecific hydrolysis of piperidinedione derivatives
11/11/1993CA2135169A1 Process for stereospecific hydrolysis of piperidinedione derivatives
11/09/1993US5260208 Enantioselective amidases, DNA sequences encoding them, method of preparation and utilization
11/02/1993US5258517 Method of preparing optically pure precursors of paroxetine
11/02/1993US5258305 Manufacture of optically active 2-phenylpropionic acid and 2-phenylpropionamide from the nitrile using Rhodococcus equi
11/02/1993US5258292 Hydrolysis of adipamide or ammonium adipamate by contact with amidase or microorganism that generates such polypeptide
10/1993
10/28/1993WO1993021336A1 Method for the preparation of d-aminoacids or d-aminoacids derivatives
10/28/1993WO1993021175A1 Chiral cyclopentene derivatives and their preparation
10/28/1993CA2133959A1 Chiral cyclopentene derivatives and their preparation
10/28/1993CA2111088A1 Method for the preparation of d-aminoacids or d-aminoacids derivatives
10/26/1993US5256803 Process for the preparation of (2R,3R)-cis)-β-phenylglycidic acid
10/26/1993US5256800 Optically active 2,2-dimethyl-1,3-dioxin-4-ones and method for preparing same
10/26/1993US5256569 Reacting alcohols with triglycerides
10/26/1993CA1323593C Process for the enzymatic preparation of l-2-amino-4- methylphosphinobutyric acid
10/20/1993EP0566485A2 Process for producing optically active halogen-containing alcohol
10/20/1993EP0355102B1 Electroenzymatic method for producing compounds having a controlled enantiomeric purity
10/19/1993US5254756 Esterification of racemate, enantioselective hydrolysis with lipase from Pseudomonas fluorescens
10/19/1993US5254464 Culture product of brevibacterium
10/05/1993US5250426 Molecules with antibody combining sites that induce asymmetry
09/1993
09/30/1993WO1993019029A1 Cycloalkyl-based chiral auxiliaries and method of making the same
09/28/1993US5248610 Process for producing optically active α-hydroxyesters using lipase PS
09/28/1993US5248609 Racemic separation of 7α-acyloxy-6β-hydroxymethyl-2-oxabicyclo[3.]-octan-3-ones by stereospecific enzymatic acylate hydrolysis
09/28/1993US5248608 Enzyme catalyzed stereospecific hdyrolysis
09/28/1993US5248601 Amination of epoxybutyric ester and hydrolysis
09/22/1993EP0561535A2 Enantiomeric enrichment of cyanohydrins
09/22/1993EP0561321A2 Additive assisted enzymatic esterification of 1,2-diol monosulfonates
09/21/1993US5247095 Intermediates for d-biotin synthesis and their production
09/21/1993US5246843 Process for preparation of R-(-)-3-halogeno-1,2,-propanediol by treatment with microorganism
09/21/1993CA2090183A1 Additive assisted enzymatic esterification of 1,2-diol monosulfonates
09/16/1993WO1993018138A1 New ketonic ester reductases, its preparation and use for enzymatic redox reactions
09/15/1993EP0560408A1 Enantio- and regioselective syntheses of organic compounds using enol esters as irreversible transacylation reagents
09/15/1993EP0559927A1 A simplified method for the production of vinyl glycine (2-aminobut-3-enioc acid) and a convenient resolution of a derivative
09/14/1993US5245055 Multistage, ylide intermediate, treatment of thrombosis
09/14/1993US5244803 Stereoselective hydrolysis by microorganism in culture
09/10/1993CA2091233A1 A simplified method for the produuction of vinyl glycine (2-aminobut-3-enioc acid) and a convenient resolution of a derivative
09/10/1993CA2090801A1 Enantiomeric enrichment of cyanohydrins
09/02/1993WO1993017120A1 Process for the enzymatic oxidation of (d)-2-hydroxycarboxylic acids to 2-ketonic carboxylic acids
09/02/1993CA2127544A1 The enzymatic oxidation of (d)-2-hydroxy carboxylic acids to 2-keto carboxylic acids
08/1993
08/31/1993US5241087 Enantiomeric enrichment of cyanohydrins
08/31/1993US5241064 Enzymatic process for preparing optically active 3-substituted azetidinones
08/26/1993DE4205391A1 Verfahren zur enzymatischen oxidation von (d)-2-hydroxycarbonsaeuren zu 2-ketocarbonsaeuren Process for the enzymatic oxidation of (d) -2-hydroxy carboxylic acids to 2-ketocarboxylic acids
08/25/1993EP0556909A1 Process for preparing (R) and(S)-1,2-isopropylideneglycerol
08/25/1993EP0556387A1 Process for preparing optically active 1,3-butanediol
08/24/1993US5238838 L-carnitine amidase produced by a microorganism
08/24/1993US5238832 Lipoxygenase inhibitors
08/24/1993US5238828 Contacting racemic nitrile compound with either psuedomonas or fusarium, recovering
08/19/1993DE4204151A1 Prepn. of pure spatial isomers of mono:glyceride(s) - by enzymatic esterification of glycerol adsorbed on solid carrier for mono:glyceride sulphate prepn. as surfactant for food, cosmetics and pharmaceuticals
08/10/1993US5234826 Subjecting DL lactonitrile or acetaldehyde and prussic acid to action of microorganisms
08/10/1993US5234821 Process for preparing 1,4 dihydropyridine compounds
08/05/1993WO1993015208A1 Chiral synthesis with modified enzymes
08/05/1993CA2127126A1 Chiral synthesis with modified enzymes
08/03/1993US5232852 Process for the production of dioxolanes
07/1993
07/27/1993US5231198 Acid catalyzed cyclization
07/27/1993US5231027 Enzymatic process for separating the optical isomers of racemic 1,2-diols using lipase
07/21/1993EP0552041A2 Enzymatic processes for resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
07/20/1993US5229280 Process for the continuous biotechnological preparation of optical isomer s(+) of 2-(6-methoxy-2-naphthyl) propionic acid
07/16/1993CA2434312A1 Enzymatic processes for resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
07/16/1993CA2087359A1 Enzymatic processes for resolution of enantiomeric mixtures of compoundsuseful as intermediates in the preparation of taxanes
07/07/1993EP0549872A2 Process for the preparation of (2R,E3)-4-halo-3-buten-2-ols
07/06/1993US5225339 Nadph <--> nadp
06/1993
06/30/1993EP0517798A4 Stereospecific resolution by hydrolysis of esters of 2-arylpropionic acids by liver enzymes
06/29/1993US5223432 Process for preparing optically pure (S)-α-((tert-butylsulfonyl)methyl)hydrocinnamic acid using protease
06/29/1993US5223416 Process for producing r(-)-mandelic acid and derivatives thereof
06/29/1993CA1319635C Process for the enzymatic resolution of the optical isomers of racemic ester derivatives of 3-mercapto-2- alkyl-propionic acid
06/15/1993US5219757 Treating racemic mixture or reducing ketone with microorganism
06/15/1993US5219743 Method for optical resolution of corey lactone diols
06/15/1993US5219731 Cleaving an oxazolone precursor with lipase
06/10/1993WO1993011255A1 Process for preparing optically active cyanohydrines by racemate separation in the presence of oxynitrilases
06/08/1993CA1318874C Process for preparing optically active hydantoins
06/07/1993WO1993011256A1 Process for producing optically active norborneol
06/01/1993US5215919 Catalytic reduction a 2-oxocycloalkanecarboxylic acid ester with bacteria Enterobacter, Escherichia, Klebsiella, Proteus, Salmonella, Serratia, Curtobacterium, Cellulomonas and Bacillus in presence of reductase
06/01/1993US5215918 Acid anhydride esterification; preferential enzymatic hydrolysis with a subtilisin protease
06/01/1993US5215897 Process for producing L-amino acids
06/01/1993CA1318627C Enzymatic resolution process
05/1993
05/25/1993US5213975 Methods of preparing optically active epoxy alcohol
05/19/1993EP0542300A2 Method of preparing (S)-1-phenyl-1,3-propanediol or derivatives thereof
05/19/1993EP0542098A1 Process of chemical racemisation of 5-monosubstituted hydantoins, device for the execution of the process and use of the hydantoin
05/18/1993US5212089 Process for prepartion of s-(+)-3-halogeno-1,2-propanediol by treatment with alcaligenes
05/11/1993US5210085 Method for the synthesis, compositions and use of 2'-deoxy-5-fluoro-3'-thiacytidine and related compounds
05/05/1993EP0539767A1 Enzymatic process for the enantioselective production of optically active cyanhydrins
05/04/1993US5208156 Esterase purified from serratia marcescens sr41 (ferm bp-no. 487)
05/01/1993CA2078942A1 Enzymatic process for the enantioselective preparation of optically active cyanohydrins
04/1993
04/27/1993US5206162 Process for making D-aminoacylase
04/21/1993EP0537921A2 Enzymatic synthesis of chiral alpha-hydroxyketones and derivatives
04/21/1993EP0537259A1 Process for producing enantiomers of 2-aryl-alkanoic acids
04/20/1993US5204466 Stereoselective preparation of biologically active isomer
04/20/1993US5204248 Process for preparing 2-halogeno-3-hydroxy-3-phenyl-propionic acid ester compounds
04/15/1993WO1993007289A1 ENZYMATIC SYNTHESIS OF CHIRAL α-HYDROXYKETONES AND DERIVATIVES
04/15/1993DE4123621A1 Enzymatisches verfahren zur herstellung von enantiomerenreinen estern und alkoholen An enzymatic process for the preparation of enantiomerically pure esters and alcohols
04/13/1993US5202260 Resolution of α-tertiary carboxylic acid esters using lipase from Candida lipolytica
04/07/1993EP0513200A4 Method and compositions for the synthesis of bch-189 and related compounds
04/06/1993US5200335 Phenylethanol dehydrogenase capable of reducing acetophenone to r(+)-phenylethanol
04/01/1993WO1993006236A1 Enzymatic production of optical isomers of tetrahydropyran-2-ones
04/01/1993WO1993006235A1 Process for the preparation of enantiomerically pure 4-hydroxytetrahydro-2-pyranone derivatives
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