| Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784) |
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| 01/27/2000 | CA2337230A1 Stereoselective reductive amination of ketones |
| 01/26/2000 | EP0974670A2 Process for producing optically active N-substituted azetidine-2-carboxylic acid compound |
| 01/20/2000 | WO2000003032A1 Method for producing (1r,4s)-2-azabicylco[2.2.1]hept-5-en-3-on derivatives |
| 01/19/2000 | EP0972845A1 Method for producing L-Allysine acetal |
| 01/19/2000 | EP0971906A1 Lipase catalyzed dynamic resolution of isoxazoline thioesters to isoxazoline carboxylic acids |
| 01/19/2000 | CN1242054A Process and composition for preparing D-aspartic acid |
| 01/19/2000 | CN1048524C Preparation of D-alpha amino acid |
| 01/18/2000 | US6015698 Method of producing D-amino acid and method of producing amine |
| 01/12/2000 | EP0970235A1 Process for the selective enzymatic hydroxylation of aldehydes and ketones |
| 01/05/2000 | EP0968302A1 Method for producing esters free of enantiomers |
| 12/29/1999 | EP0967271A1 Novel carbonyl reductase, gene that encodes the same, and method of utilizing these |
| 12/29/1999 | EP0966469A1 Method for producing heteroaromatic alcohols free of enantiomers |
| 12/22/1999 | EP0964928A1 Enzymatic resolution of benzodiazepine-acetic acid esters with a lipase |
| 12/22/1999 | EP0723586B1 Enzyme and its use in preparing (s)-pipecolic acid |
| 12/15/1999 | EP0720655B1 Racemate cleavage of primary and secondary amines by enzyme-catalysed acylation |
| 12/15/1999 | CN1238808A Process for preparation of optically active N-benzyl-3-pyrrolidinol |
| 12/14/1999 | US6001615 Stereoselectively reducing a compound by using a reductase from beauveria, candida, kluyveromyces, debaromyces, or pichia and recovering the compound |
| 12/09/1999 | WO1999063104A1 Method for stereoselective production of substituted cyclohexylcyanhydrins |
| 12/09/1999 | DE19824491A1 Verfahren zur stereoselektiven Herstellung von substituierten Cyclohexylcyanhydrinen A process for the stereoselective preparation of substituted Cyclohexylcyanhydrinen |
| 12/08/1999 | EP0765857B1 Process for producing optically active alpha-substituted carboxylic acid derivatives |
| 11/24/1999 | EP0959139A1 Method for producing optically active cyclopropanecarboxylic acid |
| 11/23/1999 | US5989900 Process for preparing optically active allylic alcohol derivatives |
| 11/18/1999 | WO1999058706A1 Novel method for preparing synthesis intermediates |
| 11/16/1999 | US5985632 Peptide amidase from xanthomonas |
| 11/10/1999 | EP0954571A1 Biocatalysts with amine acylase activity |
| 11/04/1999 | WO1999055898A1 Enzymatic resolvation for obtaining a (-)-3,4-trans-diarylchroman |
| 11/02/1999 | US5977438 Production of peptides in plants as viral coat protein fusions |
| 10/27/1999 | EP0952227A1 A bio-resolution process |
| 10/27/1999 | EP0951561A1 Enzymatic processes for preparing (s)-cyanohydrins |
| 10/26/1999 | US5973214 Method for producing an optically active 2-alkanol |
| 10/20/1999 | EP0950706A2 D-aminoacylase |
| 10/14/1999 | WO1999051722A2 Recombinant l-n-carbamoylase derived from arthrobacter aurescens, and a method for producing l-amino acids by using the same |
| 10/14/1999 | WO1999037754A3 Enzyme activated supports for enantiomeric separations |
| 10/14/1999 | DE19913741A1 New Arthrobacter aurescens recombinant L-N-carbamoylase, useful for production of amino acids |
| 10/13/1999 | EP0948484A1 The preparation of enantiomerically-enriched threo-methylphenidate |
| 10/12/1999 | US5965432 Method for improving optical purity of an amine compound |
| 10/12/1999 | US5965032 Purification of α-, β- or γ-substituted carboxylic acids |
| 10/05/1999 | US5962282 Producing cis 2-substituted tetrahydropyran-4-ol by stereospecifically hydrolysing an ester derivative using hydrolase in a racemic mixture; for forming optically active ketone derivatives |
| 10/05/1999 | US5962279 Process for producing D-amino acids with composite immobilized enzyme preparation |
| 09/30/1999 | DE19812004A1 Dehydrogenasen mit verbesserter NAD-Abhängigkeit, deren Herstellung und Verwendung Dehydrogenases with improved NAD-dependence, their preparation and use |
| 09/29/1999 | EP0945518A1 Process for producing optically active 3-quinuclidinol derivatives |
| 09/29/1999 | EP0944730A1 Method for production of d-proline derivatives |
| 09/28/1999 | US5959159 Utilizes a microbial lipase derived from chromobacterium viscosum to catalyze the enantioselective and regioselective hydrolysis of the (s)(-)-enantiomer of the racemic mixture to its corresponding monoester |
| 09/28/1999 | US5958743 Culturing candida schatavii in medium containing substrate |
| 09/23/1999 | WO1999047684A2 Dehydrogenases with improved nad-dependence, the production thereof, and their use |
| 09/16/1999 | WO1999046398A1 Improvements in the enzymatic synthesis of chiral amines |
| 09/16/1999 | CA2322605A1 Improvements in the enzymatic synthesis of chiral amines |
| 09/15/1999 | EP0942068A1 Process for the preparation of optically active n-benzyl-3-pyrrolidinol |
| 09/15/1999 | CN1228812A Microorganism, Lactamase enzyme obtained therefrom, and their use |
| 09/10/1999 | WO1999045134A1 OPTICAL RESOLUTION OF α-ALKYL-β-THIOLACTONES USING HYDROLYTIC ENZYME |
| 09/10/1999 | WO1999045133A1 Method for enzymatic enantiomer-separation of 3(r)- and 3(s)-hydroxy-1- methyl-4-(2,4, 6-trimethoxyphenyl)-1, 2,3,6- tetrahydro-pyridine or its carboxylic acid esters |
| 09/09/1999 | DE19809649A1 Verfahren zur enzymatischen Enantiomeren-Trennung von 3(R)- und 3(S)-Hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydro-pyridin bzw. der Carbonsäureester Process for the enzymatic separation of enantiomers 3 (R) - and 3 (S) -hydroxy-1-methyl-4- (2,4,6-trimethoxyphenyl) -1,2,3,6-tetrahydro-pyridine or carboxylic acid esters |
| 09/01/1999 | EP0939135A1 Substantially pure hetero-bicyclic alcohol enantiomers |
| 09/01/1999 | EP0939134A1 Processes for producing optically active 2-amino-1-phenylethanol derivatives |
| 09/01/1999 | EP0938584A2 Method of preparing (s) - or (r) -3,3,3-trifluoro-2-hydroxy-2- methylpropionic acid |
| 08/31/1999 | CA2018345C Stabilization of carboxyl esterase |
| 08/25/1999 | EP0937152A2 Screening for and use of an esterase for a stereospecific resolution |
| 08/24/1999 | US5942646 Trifluoromethylhydroxyalkyl fluoroalkyl ethers; liquid crystals |
| 08/24/1999 | US5942644 Composition of chiral beta-hydroxycarboxamides, beta-hydroxyhydraxides, and beta-hydroxyhydroxamic acids can be used for stereoselective production of aminoalcohols, such as for drugs and fungicides |
| 08/19/1999 | WO1999041405A1 Process for the enzymatic resolution of lactams |
| 08/18/1999 | EP0935669A1 Enzymatic synthesis of optically active hydroxamic acids and their conversion into optically active primary amines by lossen transposition |
| 08/18/1999 | EP0695362B1 Chiral synthesis of tertiary alcohols with a hydrolase |
| 08/12/1999 | WO1999040122A1 Device for producing polymer support materials in the form of porous polymer beads |
| 08/12/1999 | DE19804518A1 Verfahren zur Herstellung von Trägerpolymermaterialien in Form von porösen Polymerperlen Process for the preparation of carrier polymer materials in the form of porous polymer beads |
| 08/11/1999 | EP0934426A1 Process and composition for preparing d-aspartic acid |
| 08/11/1999 | CN1225393A Method for obtg. 2-amino-4-methylphosphine butanoic acid gene |
| 07/29/1999 | WO1999037754A2 Enzyme activated supports for enantiomeric separations |
| 07/29/1999 | CA2319265A1 Enzyme activated supports for enantiomeric separations |
| 07/28/1999 | EP0931139A1 Immobilized cofactor-dependent enzymes |
| 07/27/1999 | US5928933 Separating racemic mixture by enantioselectively hydrolyzing the ester of the l-isomer; chemical intermediate for 4-hydroxyproline |
| 07/14/1999 | EP0784698A4 Biological resolution of racemic indene oxide to (1s,2r)-indene oxide |
| 07/14/1999 | EP0696282B1 Process for preparing intermediates for the synthesis of antifungal agents |
| 07/13/1999 | US5922736 Chronic, bolus administration of D-threo methylphenidate |
| 07/13/1999 | US5922602 This invention is in the field of gene regulation through anti-sense rna endogenously produced inhibitory rna molecules such as anti-sense rna and co-suppressor rna. |
| 07/08/1999 | WO1999034010A1 Process for producing optically active alcohols |
| 07/07/1999 | CN1221793A Enzyme with deaminizating formyl activity |
| 07/06/1999 | US5919672 Adding racemic lactam to microorganism media containing buffer and solvent or enzyme with solvent and buffer to obtain an isomer, hydrolyzing the carboxylic ester of the compound to form an acid |
| 06/30/1999 | EP0926131A2 Process for the preparation of aminoalcohol derivatives and their further transformation zu (1R,4S)-4-((2-amino-6-chlor-5-formamido-4-pyrimidinyl)-amino)-2-cyclopenten-1-methanol |
| 06/30/1999 | EP0925361A1 Microorganism, lactamase enzyme obtained therefrom, and their use |
| 06/29/1999 | US5916781 Comprises contacting d,l-tryptophan mixture with tryptophanase, microorganism producing tryptophanase, or treated product of microorganism producing tryptophanase to selectively degrade l-tryptophan, thereby increasing content |
| 06/29/1999 | US5916774 D-aminoacylase |
| 06/24/1999 | WO1999031264A1 Resolution of chiral amines |
| 06/24/1999 | CA2313684A1 Resolution of chiral amines |
| 06/23/1999 | EP0924194A2 Processes for producing optically active 2-amino-1-phenylethanol derivatives |
| 06/23/1999 | EP0924193A1 Processes for producing optically active 2-amino-1-phenylethanol derivatives |
| 06/23/1999 | CN1220702A Process for producing optically active amines |
| 06/23/1999 | CN1220695A Process for preparation of amino alcohols and derivatives thereof |
| 06/22/1999 | US5914400 Method and compositions for the synthesis of BCH-189 and related compounds |
| 06/22/1999 | US5914263 Enzymatic process for the stereoselective preparation of a hetero-bicyclic alcohol enantiomer |
| 06/17/1999 | WO1999029889A1 A method for producing hydroxycarboxylic acids by auto-degradation of polyhydroxyalkanoates |
| 06/15/1999 | US5912355 Enantiomorphs as intermediates for drugs and agrochemicals |
| 06/15/1999 | US5912164 Stereoselective hydrolysis of chiral carboxylic acid esters using esterase from ophiostoma or ceratocystis |
| 06/09/1999 | CN1218797A Process for preparing optical 2-amino-omega-oxo alkane acid derivative |
| 06/09/1999 | CN1218795A Process for preparation of aminoalcohol derivatives and their further conversion to (1R,4S)-4-((2-amino-6-chloro-5-formamido-4-pyrimidinyl) amino)-2-cyclopentenyl-1-methanol |
| 06/08/1999 | US5910437 Ligated d-protein of formula r-l-r' where r and r' are peptides and l is linking group of thiol ester or selenol ester; for production of chirally pure chemicals and drugs; production of racemic crystals; prolonged half-life in body |
| 06/02/1999 | EP0919630A1 Process for producing l-allysine acetals |
| 06/02/1999 | CN1218110A Novel esterase and methods for production of optically active chroman compounds |
| 05/27/1999 | CA2591571A1 Process for the preparation of aminoalcohol derivatives and their further conversion to (1s,4r)- or (1r,4s)-1-amino-4-(hydroxymethyl)-2-cyclopentene |
| 05/25/1999 | CA2038011C Processes for preparing 2-halogeno-3-hydroxy-3-phenyl-propionic acid ester compounds |
| 05/12/1999 | EP0914464A1 Process for the preparation of optically active methadones in high enantiomeric purity |