Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
12/2003
12/16/2003US6664083 Adjusting stereospecificiy of amino acid seqences; obtain sample polypeptides, incubate with enzyme, recover stereospecific compound
12/16/2003CA2068614C Esterase genes, esterase, recombinant plasmids and transformants containing the recombinant plasmid and methods of producing optically active carboxylic acids and their enantiomeric esters using said transformants
12/11/2003WO2003010311A3 Process for preparing variant polynucleotides
12/10/2003EP1123410B1 The enzyme-mediated synthesis of peptidomimetics
12/10/2003EP0658211B2 Enzymatic asymmetric reduction process to produce 4 h-thieno(2,3-6)thio pyrane derivatives
12/09/2003US6660500 Nucleotide sequences coding envelope protein for use in prevention of viral disease and parasitic infections
12/04/2003WO2003100050A1 Hydantoin racemase
12/04/2003WO2002081626A3 D-hydantoinase from ochrobactrum anthropi
12/03/2003EP1367132A1 Process for preparation of optically active propoxyaniline derivatives
12/03/2003EP1367129A2 Method for the enzymatic preparation of enantiomerically-enriched beta-amino acids
12/02/2003US6656710 Racemization of preferential amino acids; obtain chemical intermediate, incubate with preferential enzyme, recover amino acid
11/2003
11/27/2003WO2003097851A1 Process for producing optically active alkylcarboxylic acid derivative
11/27/2003WO2003097810A2 Nitrilases, nucleic acids encoding them and methods for making and using them
11/27/2003US20030219897 A vector for transfecting a plant cell, obtained from a tomato mosaic virus, a tobacco masaic virus, producing an antisense RNA or a suppressor RNA, for inhibiting or reducing of gene expression
11/27/2003US20030219879 Method for producing D-allo -isoleucine
11/27/2003CA2486062A1 Nitrilases, nucleic acids encoding them and methods for making and using them
11/26/2003EP1365029A1 Process for producing (3r,5s)-(e)-7- 2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-3,5-dihydroxyhept-6-enic acid esters
11/26/2003EP1365023A1 Dna encoding novel d-aminoacylase and process for producing d-amino acid by using the same
11/25/2003CA2064349C Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids
11/19/2003EP1235832B1 Vitamin d prescursors, method and intermediates
11/19/2003CN1457362A DNA encoding novel D-aminoacylase and process for producing D-amino acid by using the same
11/19/2003CN1456676A Enzyme preparing method for š�-amino acid of enriched antipode
11/13/2003WO2003010183A3 Process for preparing variant polynucleotides
11/12/2003CN1127574C Method for producing esters free of enantiomers
11/11/2003US6645746 Expression vector; transformants; E. coli; Candida; Bacillus; use of microorganisms to produce t-butyl(3R,5S)-6-chloro-3,5 -dihydroxyhexanoate, by enzymatic asymmetrical reduction, for drug, pesticide and HMG-CoA reductase inhibitor synthesis
11/06/2003WO2003091423A1 Adh from rhodococcus erythropolis
11/06/2003WO2003091196A1 Process for the enantioselective synthesis of propargyl alcohol derivatives of r configuration from the racemic mixtures thereof
11/06/2003WO2002086126A3 Enzymatic method for the enantioselective reduction of keto compounds
11/06/2003WO2002077250A3 Process for the production of enantiomer-enriched alpha-substituted carboxylic acids
11/06/2003US20030207436 From an N-acyl-D-amino acid, wherein a minimum reaction rate is specified when forming D-tryptophan from N-acetyl-D-tryptophan in an aqueous medium
11/05/2003EP1358215A2 Glycosaminoglycans derived from k5 polysaccharide having high antithrombin activity and process for their preparation
11/05/2003CN1453362A Chemical-enzymatic synthesis process for optical-enriched rose oxide
11/04/2003US6642035 Synthesis of B-keto esters
10/2003
10/30/2003WO2003010312A3 Nucleic acid sequences encoding enantioselective amidases
10/29/2003EP1141374B1 Method for producing optically active 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives
10/29/2003CN1452603A Process for preparing (-) mentrol and similar compounds
10/28/2003US6638759 Process for preparation of optically active 1,2-diols by cultivating microorganisms
10/28/2003US6638758 Process for the enzymatic resolution of lactams
10/23/2003WO2003087387A1 Chemo-enzymatic synthesis of optically enriched rose-oxides
10/23/2003US20030199048 Polypeptides, capable of stereoselective hydrolysis of chiral feruloyl ester into ferulic acid and an alcohol
10/21/2003US6635284 Delivery of multiple doses of medications
10/16/2003WO2003085120A1 PROCESS FOR PRODUCING EITHER OPTICALLY ACTIVE N-SUBSTITUTED ß-AMINO ACID AND OPTICALLY ACTIVE N-SUBSTITUTED ß-AMINO ACID ESTER OR OPTICALLY ACTIVE N-SUBSTITUTED 2-HOMOPIPECOLIC ACID AND OPTICALLY ACTIVE N-SUBSTITUTED 2-HOMOPIPECOLIC ACID ESTER
10/16/2003WO2003043575A3 Process for the synthesis of (r)-1-(3,5-bis(trifluoromethyl)-phenyl)ethan-1-ol and esters thereof by dynamic kinetic resolution
10/16/2003WO2003020921A3 Novel pyruvate decarboxylase, production and use thereof
10/16/2003CA2481839A1 Process for producing either optically active n-substituted .beta.-amino acid and optically active n-substituted .beta.-amino acid ester or optically active n-substituted 2-homopipecolic acid and optically active n-substituted 2-homopipecolic acid ester
10/15/2003EP1352900A1 Process to prepare taxol
10/15/2003EP1352899A1 Process to prepare taxol
10/15/2003EP1351918A1 Preparation of enantiomerically pure hydroxy esters and acids
10/15/2003CN1449447A Butinol I esterase
10/15/2003CN1124347C Method for obtg. 2-amino-4-methylphosphine butanoic acid gene
10/09/2003WO2003083126A2 Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates
10/09/2003US20030190743 Enzymatic process for the resolution of enantiomeric mixtures of beta-lactams
10/08/2003EP1349950A1 A process for the preparation of 1-(3-trifluoromethylphenyl)-propan-2-ol enantiomers
10/02/2003WO2003080855A2 Deracemisation of amines
10/02/2003WO2003080854A2 Process for preparing optically active beta-aminocarboxylic acids from racemic n-acylated beta-aminocarboxylic acids
10/02/2003US20030187262 Viricides, anticancer agents
10/02/2003US20030186412 Polypeptides which asymmetrically reduce N-benzyl-3-pyrrolidinone to produce (S)-N-benzyl-3-pyrrolidinol with NADPH as coenzyme
10/02/2003US20030186396 Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives
10/02/2003US20030186395 Chemo-enzymatic synthesis of optically enriched rose-oxides
10/02/2003CA2480301A1 Process for preparing optically active beta-aminocarboxylic acids from racemic n-acylated beta-aminocarboxylic acids
10/01/2003EP1348765A1 Process for the preparation of optically active azabicyclo heptanone derivatives
10/01/2003EP1348025A2 Enzymatic deprotection of amines and hydroxides
10/01/2003EP0873290B1 Process for racemization of n-acetyl-d(l)-alpha-aminocarboxylic acids
10/01/2003EP0846759B1 Gene encoding protein having asymmetric hydrolase activity on 4-substituted-1,4-dihydropyridine derivatives and expression product of the same
09/2003
09/25/2003WO2003078615A1 Alcohol dehydrogenases with high solvent and temperature stability
09/25/2003US20030180896 Biocatalytic reduction of 8-chloro-6-oxo-octanoic alkyl ester in presence of Mucor racemosus or Geotrichum candidum to form 8-chloro-6-hydroxyoctanoic acid methyl ester
09/25/2003CA2474905A1 Alcohol dehydrogenases with high solvent and temperature stability
09/23/2003US6624311 Enantioselective enzymatic aminolysis of a racemic 2-isoxazolylacetate alkyl ester
09/18/2003WO2003076384A1 Resolution of chiral compounds using aminocyclopentadienyl ruthenium catalysts
09/18/2003US20030175910 Whole cell catalyst
09/18/2003CA2478408A1 Resolution of chiral compounds using aminocyclopentadienyl ruthenium catalysts
09/17/2003EP1343902A2 Recombinant porcine liver esterases, their use and a method for the production thereof
09/17/2003EP1151992B1 Method for purifying and isolating (2s,3s)- or (2r,3s)-halohydrin derivatives
09/17/2003CN1121497C D-pantolactone hydrolase and gene encoding the same
09/16/2003US6620600 Enzymatic resolution of aryl and thio-substituted acids
09/12/2003WO2003074717A1 Process for preparation of optically active allenes
09/11/2003US20030170869 D-aminoacylases, method for producing the same, and method for producing D-amino acids using the same
09/11/2003US20030170835 Esterase, its DNA, its overexpression and production of optically active aryl propionic acids using the same
09/10/2003EP1342788A1 Process for producing optically active (4r)-1,3-tiazolidine-4-carboxylic acid
09/10/2003EP1341927A1 Method of preparing 3- 2- (methylsulfonyl)oxy ethoxy]-4-(triphenylmethoxy)-1-butanol, methane sulfonate
09/10/2003EP0725142B1 Process for producing d-amino acid by using composite immobilized enzyme preparation
09/09/2003US6617127 Synthesis and recovery of aspartame involving enzymatic deformylation step
09/04/2003WO2003072793A2 Method for producing alcohols from substrates by using oxide reductases, two-phase system comprising an aqueous phase and an organic phase and device for carrying out said method
09/04/2003WO2003072792A2 A method of selectively producing male or female sterile plants
09/04/2003US20030166226 Mixing (1a,3b,5E,7E,20R)-1,3-bis(tert-butyldimethylsiloxy)-20-(3'-cyclopropyl -3'(R,S)-hydroxy-1'-propenyl)-9,10-secopregna-5,7,10(19)-triene with lipase
09/04/2003US20030166178 Contacting with hydantoinase, carbamoylase and racemase; Bacillus and Agrobacterium; can convert into catalyst or bioactive compound
09/04/2003CA2777599A1 A method of selectively producing male or female sterile plants
09/02/2003US6613934 Enantiomerically enriched malonic acid monoesters substituted by a tertiary hydrocarbon radical, and their preparation
09/02/2003US6613550 Microbial process for preparation of optically active 3-hydroxypyrrolidine derivatives
08/2003
08/21/2003US20030157672 Nitrilase from rhodococcus rhodochrous ncimb 11216
08/19/2003CA2287560C Stereoselective microbial reduction of a racemic tetralone
08/14/2003WO2003066873A1 Esterases with lipase activity
08/14/2003WO2002029079A3 Enantioselective production of amino carboxylic acids
08/14/2003US20030153031 Esterification of racemic mixture in solvent
08/14/2003CA2475094A1 Esterases with lipase activity
08/07/2003US20030150019 Comprises plant viral RNA sequences comprising cis-acting replication elements for transfection and expression of heterologous proteins in plants such as tobacco
08/07/2003US20030149281 Protected 3,-5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production
08/07/2003US20030148481 Lipase catalyzes reaction of fluorinated carboxylic acid ester with alcohols, wherein fast and slow reacting enantiomers are separated by distribution between organic and fluorous phases; for production of drugs and plant protective agents
08/07/2003US20030148472 Comprises nucleotide sequences coding hydantoinase/hydrolases for producing pharmaceuticals, chemical industrial products and food
08/07/2003US20030148443 Epoxide hydrolases, nucleic acids encoding them and methods of making and using them
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