| Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784) |
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| 04/28/2004 | EP1412323A1 Protected 3,5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and derivatives and method for the production and use thereof |
| 04/28/2004 | EP1412322A2 Protected 3.5-dihydroxy-2.2-dimethyl-valeroamides for the synthesis of epothilone and derivatives and method for the production and use thereof |
| 04/28/2004 | EP1411943A2 Methods for treatment of cognitive and menopausal disorders with d-threo methylphenidate |
| 04/28/2004 | EP0513200B2 Method and compositions for the synthesis of bch-189 and related compounds |
| 04/27/2004 | US6727088 Process for preparation of (R)-1, 2-propanediol by microbes |
| 04/27/2004 | US6727083 Protein for use in the generation of bronchodilating agent, pesticides, fungicide, herbicides and for use in the treatment of diabetes |
| 04/22/2004 | US20040077864 A ketoxime of given formula, palladium as a reduction and racemization catalyst, lipase as a stereoselective acylation catalyst, an acyl donor, and a tertiary amine react in an organic solvent to provide a chiral amide which is hydrolyzed |
| 04/22/2004 | US20040077061 Enzymatic resolution of aryl and thio-substituted acids |
| 04/22/2004 | US20040077060 Treatment of a lactic acid ester derivative with an enzyme or the like, which has asymmetric ester-hydrolyzing ability, can specifically hydrolyze the ester moiety of an isomer existing as the pair to the racemic derivative; microbiocides |
| 04/22/2004 | US20040077059 Process for the preparation of enantiomerically enriched esters and alcohols |
| 04/21/2004 | EP1409691A2 Stereoselective preparation of cyclic l-amino acids |
| 04/21/2004 | EP1409688A2 Nucleic acid sequences encoding enantioselective amidases |
| 04/21/2004 | EP1409667A2 Process for preparing variant polynucleotides |
| 04/20/2004 | US6723868 Process for the preparation of aminoalcohol derivatives and their further conversion to (1R,4S)-4-((2-amino-6-chloro-5-formamido-4-pyrimidinyl)-amino)-2-cyclopentenyl-1-methanol |
| 04/15/2004 | US20040072310 Enzymatic resolution of aryl and thio-substituted acids |
| 04/15/2004 | US20040072309 Method for producing 2-azetidinone derivative |
| 04/15/2004 | US20040072308 Culturing microorganism with enhanced serine deaminase activity and producing sterospecific serine for use in preparation of cycloserine |
| 04/14/2004 | EP1408107A2 Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene |
| 04/14/2004 | EP1407037A1 Process for manufacturing of tagatose |
| 04/14/2004 | EP1407009A2 Hydrolase enzymes and their use in kinetic resolution |
| 04/14/2004 | EP1406853A1 Process for the racemization of alcohols |
| 04/13/2004 | US6720183 Cytoplasmic inhibition of gene expression |
| 04/13/2004 | US6720169 By converting the corresponding acetal-protected aldehyde into the corresponding aminonitrile, converting the aminonitrile into the corresponding amino acid amide, and performing enzymatic, enantioselective hydrolysis |
| 04/07/2004 | EP1404854A2 Process for the preparation of enantiomer-enriched amino acids |
| 04/06/2004 | US6717006 Reacting aldehyde or ketone with hydrocyanic acid stirred aqueous-solvent emulsion; reduced enzyme and time requirements |
| 04/01/2004 | US20040064855 Production of lysosomal enzymes in plants by transient expression |
| 03/30/2004 | US6713288 Converts 5-monosubstituted hydantoins to l- or d-amino acids for the production of enantiomerically enriched amino acids |
| 03/25/2004 | WO2004024934A1 Process for producing optically active erythro 3-cyclohexylserines |
| 03/25/2004 | WO2004018466A3 A method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives |
| 03/25/2004 | WO2003080854A3 Process for preparing optically active beta-aminocarboxylic acids from racemic n-acylated beta-aminocarboxylic acids |
| 03/25/2004 | US20040058422 Process for preparing (-)- menthol and similar compounds |
| 03/25/2004 | CA2497811A1 Process for producing optically active erythro 3-cyclohexylserines |
| 03/24/2004 | CN1484695A Enzymatic deprotection of amines and hydroxides |
| 03/24/2004 | CN1484631A Preparation of enantiomerically pure hydroxy esters and acids |
| 03/18/2004 | WO2004022766A1 PROCESS FOR PRODUCING L-α-METHYLCYSTEINE DERIVATIVE |
| 03/18/2004 | WO2004022764A2 Use of malate dehydrogenase for nadh regeneration |
| 03/18/2004 | WO2003072792A3 A method of selectively producing male or female sterile plants |
| 03/18/2004 | US20040054216 Method for producing lysine derivative |
| 03/18/2004 | US20040053401 Preparation of enantiomerically pure hydroxy esters and acids |
| 03/18/2004 | US20040053382 Oxidizing an alpha-amino-carboxylic acid, hydrate, or salt thereof using a L-amino acid deaminase or oxidase and subsequently reducing the product thereof using a dehydrogenase |
| 03/18/2004 | CA2497499A1 Use of malate dehydrogenase for nadh regeneration |
| 03/17/2004 | CN1142189C Device for producing macromolecule materials in form of porous polymer bead carrier and its preparing process and application |
| 03/16/2004 | US6706500 Generation of preferential menthol; obtain reaction mixture, incubate with lipase, recover menthol |
| 03/11/2004 | WO2003035878A3 Lipase variants |
| 03/11/2004 | US20040049067 Process for the enantioselective synthesis of propargyl alcohol derivatives of R configuration from the racemic mixtures thereof |
| 03/11/2004 | US20040049025 Recombinant viral nucleic acids |
| 03/11/2004 | DE10240603A1 Verwendung von Malat-Dehydrogenase zur NADH-Regenerierung Use of malate dehydrogenase for NADH regeneration |
| 03/04/2004 | WO2004018466A2 A method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives |
| 03/04/2004 | US20040043460 Process for producing optically active pyridineethanol derivatives |
| 03/04/2004 | US20040043459 Racemization and deprotection of special N-protected amino acids in the acylase/racemase system for the total conversion of special N- protected racemic amino acids into optically pure amino acids |
| 03/04/2004 | CA2493244A1 A method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives |
| 02/29/2004 | WO2004016767A2 Evolving new molecular function |
| 02/29/2004 | CA2495881A1 Evolving new molecular function |
| 02/26/2004 | WO2002101003A3 Stereoselective preparation of cyclic l-amino acids |
| 02/26/2004 | WO2002092828A3 Process for the preparation of substituted carboxylic acid estersby enzymatic hydrolysis |
| 02/25/2004 | CN1477203A Method for preparing optical pure phenylethanediol by utilizing microbial stereoselectivity transformation and its special-purpose microbe |
| 02/19/2004 | DE10234764A1 Racemization of 5-tert-butylhydantoin, useful as precursor of tert-leucine, using peptide with hydantoin racemase activity, also preparation of tert-leucine |
| 02/17/2004 | US6692944 Alkoxyhalogentating racemic citronellol; dehydrohalogenating to 3-octenol derivative; acylating; biocatalytically resolving isomers; hydrolyzing and cyclizing |
| 02/12/2004 | WO2003020943A3 Enzymatic method for the enantiomeric resolution of amino acids |
| 02/12/2004 | WO2002057411A3 Hydrolase enzymes and their use in kinetic resolution |
| 02/12/2004 | US20040030139 Process for producing (3R,5S)-(E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin- 3-yl]-3, 5-dihydroxyhept-6-enic acid esters |
| 02/12/2004 | US20040029236 Process for the enzymatic preparation of enantiomer-enriched beta-amino acids |
| 02/10/2004 | US6689591 Method of reducing keto-carboxylic acids and their esters |
| 02/05/2004 | US20040023281 Production of lysosomal enzymes in plants by transient expression |
| 02/04/2004 | EP1238094B1 Method for the production of optically active cyanohydrins using r-oxynitrilase |
| 02/03/2004 | US6686181 Method for the production of L-amino acids from their racemic N-aceytyl-D, L-derivatives by enzymatic racemate cleavage by means of isolated recombinant enzymes |
| 01/28/2004 | EP1383899A2 Enzymatic method for the enantioselective reduction of keto compounds |
| 01/28/2004 | EP1383886A2 D-hydantoinase from ochrobactrum anthropi |
| 01/28/2004 | EP1095160B1 Method for producing (1r,4s)-2-azabicyclo 2.2.1 hept-5-en-3-on derivatives. |
| 01/28/2004 | EP1054996B1 Process for the enzymatic resolution of lactams |
| 01/28/2004 | CN1471584A Process for preparing (-)-menthol and the like compounds |
| 01/28/2004 | CN1136318C Process for producing optically active amines |
| 01/27/2004 | US6682916 Chemical intermediate for drugs; reduction using enzyme |
| 01/22/2004 | WO2004007741A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE β-AMINONITRILE COMPOUND AND AMIDE COMPOUND AS ANTIPODE THEREOF |
| 01/22/2004 | WO2003083126A3 Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates |
| 01/22/2004 | US20040016021 Recombinant viral expression constructs of human alpha galactosidase nucleotide sequences |
| 01/22/2004 | US20040014195 Nitrilases have increased activity and stability at increased pH and temperature |
| 01/22/2004 | US20040014182 Nucleotide sequence encoding a benzaldehyde lyase, and process for stereoselectively synthesizing 2-hydroxyketones |
| 01/22/2004 | US20040014181 Wherein a phenylacetic acid derivative is brought into contact with a mixture of enantiomers of an amine in the presence of a Pen-G acylase derived from Alcaligenes faecalis |
| 01/20/2004 | US6680183 Production of optically active 2-substituted tetrahydropyran-4-ones |
| 01/15/2004 | WO2004005517A2 L-amidase from rhizobium huautlense |
| 01/15/2004 | WO2004005241A1 Process for producing optically active amide |
| 01/15/2004 | WO2003072793A3 Method for producing alcohols from substrates by using oxide reductases, two-phase system comprising an aqueous phase and an organic phase and device for carrying out said method |
| 01/15/2004 | US20040009561 Comprises enzymatic polypeptide with amino acid oxidase activity for preparation of chemical intermediates for antibiotics and hypotensive agents |
| 01/08/2004 | WO2004003001A1 Process for the enzymatic resolution of 1,3-dioxolane-4-carboxylates |
| 01/07/2004 | CN1133749C Process for preparing enantiomericaly enriched N-derivatised lactams |
| 01/02/2004 | EP1375649A1 D-amino acid oxidase from Arthrobacter protophormiae |
| 01/02/2004 | EP1375495A1 Method for producing 2-azetidinone derivative |
| 01/02/2004 | EP1373548A1 Chemo-enzymatic synthesis of optically enriched rose-oxides |
| 01/02/2004 | EP1373522A2 D-carbamoylase from arthrobacter crystallopoietes dsm 20117 |
| 01/01/2004 | US20040002147 Improved activity and stability at increased pH/temperature; solid phase synthesis; immunoassays |
| 12/31/2003 | WO2002061107A3 Process for the preparation of enantiomer-enriched amino acids |
| 12/24/2003 | WO2003106691A1 POLYPEPTIDES HAVING alpha- H-alpha-AMINO ACID AMIDE RACEMASE ACTIVITY AND NUCLEIC ACIDS ENCODING THE SAME |
| 12/24/2003 | WO2003106689A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE alpha-METHYLCYSTEINE DERIVATIVE |
| 12/24/2003 | WO2003060094A3 Selective enzymatic esterification and solvolysis of epimeric vitamin d analog and separation of the epimers |
| 12/24/2003 | CA2486350A1 Process for producing optically active .alpha.-methylcysteine derivative |
| 12/18/2003 | WO2003044206A3 Process for the preparation of an enantiomerically enriched a-amino acid |
| 12/18/2003 | US20030232857 Side effects reduction; for treating nervous system disorders (attention deficit/hyperactivity, and cognitive decline associated with acquired immunodeficiency syndrome) |
| 12/17/2003 | EP1283845B1 Process for the preparation of pharmaceutically acceptable salts of (ss-rs)-s-adenosyl-l-methionine |
| 12/16/2003 | US6664412 Method for producing lysine derivative |