| Patents for C07D 453 - Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids (5,704) |
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| 07/09/2014 | EP2751101A1 Compounds useful as inhibitors of choline kinase |
| 07/08/2014 | US8772511 Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists |
| 07/08/2014 | US8772491 Process for the preparation of solifenacin succinate |
| 07/08/2014 | US8772314 Glycine derivatives and medicinal compositions thereof |
| 07/08/2014 | CA2512582C Antibacterial agents |
| 07/02/2014 | CN103906741A 氨烷基取代的n-噻吩基苯甲酰胺衍生物 Aminoalkyl-substituted n- thienyl benzamide derivative |
| 07/02/2014 | CN103906739A 用于制备hcv的大环蛋白酶抑制剂的方法和中间体 Method for preparing a macrocyclic protease inhibitors and intermediates hcv |
| 07/02/2014 | CN103896938A 一种琥珀酸索利那新的制备方法 One kind of solifenacin succinate new preparation method |
| 07/02/2014 | CN103896860A 含有锌结合基的不可逆egfr抑制剂 Zinc binding group containing irreversible inhibitors of egfr |
| 07/01/2014 | US8765955 Asymmetric aldol additions using bifunctional cinchona-alkaloid-based catalysts |
| 07/01/2014 | US8765785 Solifenacin salts |
| 07/01/2014 | US8765764 2-acylaminothiazole derivative or salt thereof |
| 06/26/2014 | WO2014095920A1 New cyclohexyl and quinuclidinyl carbamate derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activity |
| 06/24/2014 | US8759524 Production process of optically active 3-quinuclidinol derivative |
| 06/19/2014 | US20140171646 Amorphous forms of palonosetron hydrochloride |
| 06/19/2014 | US20140171414 Novel compounds |
| 06/19/2014 | US20140171407 1,7-diazacarbazoles and methods of use |
| 06/18/2014 | EP2742940A1 Salts of aza-bicyclo-di-aryl ethers for adminstration once daily, twice daily or thrice daily |
| 06/17/2014 | US8754074 Vinyl quinuclidine useful as a synthesis intermediate in the preparation of (R)-mequitazine |
| 06/12/2014 | WO2014086927A1 Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| 06/12/2014 | WO2014086924A1 Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| 06/12/2014 | WO2014086855A1 Phenylethylpyridine derivatives as pde4-inhibitors |
| 06/12/2014 | WO2014086852A1 Phenylethylpyridine derivatives as pde4-inhibitors |
| 06/12/2014 | WO2014086849A1 Phenylethylpyridine derivatives as pde4-inhibitors |
| 06/12/2014 | US20140163067 Methods of Treatment of Limited Cognitive Impairment |
| 06/12/2014 | US20140163066 Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| 06/12/2014 | US20140163000 Compounds useful as inhibitors of atr kinase |
| 06/12/2014 | US20140162999 Pim kinase inhibitors and preparation methods and use in medicinal manufacture thereof |
| 06/12/2014 | US20140161736 Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| 06/10/2014 | US8748613 Quinuclidine esters of 1-azaheterocyclylacetic acid as antimuscarinic agents, process for their preparation and medicinal compositions thereof |
| 06/05/2014 | US20140155429 Treatment of Cognitive Disorders with Certain Alpha-7 Nicotinic Acid Receptor Agonists in Combination with Nicotine |
| 06/05/2014 | US20140155428 Novel compounds |
| 06/05/2014 | US20140155427 Novel compounds |
| 06/05/2014 | US20140155386 Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors |
| 06/05/2014 | US20140155373 Novel compounds |
| 06/03/2014 | US8742096 Methods and compositions for preparing noribogaine from voacangine |
| 05/22/2014 | WO2014078454A1 Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain |
| 05/22/2014 | WO2014077401A1 Nitrogen-containing heterocyclic compound |
| 05/21/2014 | EP2731946A1 Salts of aza-bicyclic di-aryl ethers and methods to make them or their precursors |
| 05/21/2014 | CN103814026A 可用作胆碱激酶抑制剂的化合物 Compounds useful as inhibitors of choline kinase |
| 05/21/2014 | CN103814025A 可用作胆碱激酶抑制剂的化合物 Compounds useful as inhibitors of choline kinase |
| 05/21/2014 | CN103804373A 一种盐酸阿扎司琼的合成工艺 A synthesis of hydrochloric acid azasetron |
| 05/14/2014 | EP2729445A1 Cyclic amine derivatives as ep4 receptor antagonists |
| 05/14/2014 | CN103787969A 一种(1s)-1-苯基-3,4-二氢-2（1h）-异喹啉甲酸酯的制备方法 One kind of (1s) -1- phenyl-3,4-dihydro -2 (1h) - isoquinoline carboxylate of Preparation |
| 05/14/2014 | CN102292335B (2s,3r)-n-2-((3-吡啶基)甲基)-1-氮杂双环[2.2.2]辛-3-基)-3,5-二氟苯甲酰胺的制备和治疗应用 (2s, 3r) -n-2 - ((3- pyridinyl) methyl) -1-azabicyclo [2.2.2] oct-3-yl) -3,5-difluorophenyl-carboxamide and therapeutic use |
| 05/14/2014 | CN101484424B 治疗化合物 Therapeutic compounds |
| 05/13/2014 | US8722891 Conjugate addition reactions using bifunctional Cinchona-alkaloid-based catalysts |
| 05/08/2014 | WO2014069554A1 Quinuclidine amide derivative and medicinal use of same |
| 05/08/2014 | WO2014067219A1 Preparation method of (1s)-1-phenyl-3,4-dihydro-2(1h)-isoquinoline carboxylate |
| 05/08/2014 | US20140128365 Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors |
| 05/07/2014 | CN102115446B 一种催化合成手性姜黄素类似物的方法 A catalytic synthesis of chiral curcumin analogues method |
| 05/06/2014 | US8716309 Pharmaceutical composition comprising pyridone derivatives |
| 04/30/2014 | EP2723734A1 Process for the preparation of solifenacin and salts thereof |
| 04/30/2014 | CN103755699A Preparation method of 2-hydroyxl-2,2-dithienyl-2-polyglycolic acid-1-azabicyclo[2, 2, 2] octyl-3(R)-base ester |
| 04/30/2014 | CN103755698A Technology for preparing aclidinium bromide employing one-pot process |
| 04/30/2014 | CN101668742B Bridged six-membered ring compounds |
| 04/29/2014 | US8710227 Crystalline form of (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate |
| 04/17/2014 | US20140107027 Methods and compositions for treating amyloid-related diseases |
| 04/16/2014 | EP2718280A1 Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| 04/16/2014 | CN103724343A Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof |
| 04/15/2014 | US8697722 Nicotinic acetylcholine receptor modulators |
| 04/10/2014 | WO2014055955A1 Gdf-8 inhibitors |
| 04/09/2014 | CN103717596A Salts of aza-bicyclic di-aryl ethers and methods to make them or their precursors |
| 04/08/2014 | US8691864 Agents useful for reducing amyloid precursor protein and treating dementia and methods of use thereof |
| 04/08/2014 | US8691841 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and use thereof |
| 04/08/2014 | US8691840 N-biarylamides |
| 04/03/2014 | WO2014051055A1 Quinuclidine urea derivatives and medicinal use thereof |
| 04/02/2014 | CN103702997A Process for the preparation of solifenacin and salts thereof |
| 04/02/2014 | CN103702980A Cyclic amine derivatives as EP4 receptor antagonists |
| 03/27/2014 | US20140088080 Imidazopyridine compounds |
| 03/27/2014 | US20140088078 Partially Saturated Tricyclic Compounds and Methods of Making and Using Same |
| 03/20/2014 | WO2014043068A1 Glucosylceramide synthase inhibitors |
| 03/20/2014 | US20140080863 Muscarinic acetylcholine receptor antagonists |
| 03/19/2014 | CN103649084A 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof |
| 03/19/2014 | CN103641816A Compounds and compositions as protein kinase inhibitors |
| 03/13/2014 | US20140073624 Biaryl Heterocyclic Compounds and Methods of Making and Using the Same |
| 03/11/2014 | CA2501932C Use of benzimidazole quinolinones for treating cancer |
| 03/06/2014 | US20140066436 Pyrimidine derivatives as protein kinase inhibitors |
| 03/05/2014 | EP2702041A1 Alkaloid ester and carbamate derivatives and medicinal compositions thereof |
| 03/05/2014 | CN103613590A Method of preparing isoquinine ring compound by adopting micro-channel modular reaction device |
| 02/27/2014 | US20140058100 Tetrahydroisoquinolin-1-one derivative or salt thereof |
| 02/27/2014 | US20140057921 3-(heteroaryl-oxy)-2-alkyl-1-aza-bicycloalkyl derivatives as alpha. 7-nachr ligands for the treatment of cns diseases |
| 02/26/2014 | EP2699570A1 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof |
| 02/26/2014 | EP2699535A1 Method for producing compound with carbonyl group by using ruthenium carbonyl complex having tridentate ligand as dehydrogenation oxidation catalyst |
| 02/26/2014 | CN102372692B 二氢吡啶衍生物 Dihydropyridine derivatives |
| 02/20/2014 | WO2014027045A1 Chemical process |
| 02/20/2014 | WO2014026467A1 Bicyclic substituted pyrimidine compounds |
| 02/20/2014 | US20140051721 Stable crystalline salt of (r)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabicyclo [2.2.2]oct-3-yl ester |
| 02/20/2014 | US20140051687 Substituted indole compounds having nos inhibitory activity |
| 02/18/2014 | CA2755954C Quaternary quinuclidine derivatives and their use as muscarinic receptor antagonists |
| 02/13/2014 | US20140045880 Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders |
| 02/13/2014 | US20140045779 Compounds containing an alicyclie structure and anti-tumor application |
| 02/12/2014 | CN103570708A Alkaloid dipolymer derivative product and preparation method thereof |
| 02/05/2014 | CN103562198A Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| 02/05/2014 | CN103554101A 3-(heteroaryl-oxy)-2-alkyl-1-aza-bicycloalkyl derivatives as alpha7-nachr ligands for the treatment of cns diseases |
| 02/04/2014 | US8642764 Julolidine conjugates and methods for their preparation and use |
| 01/30/2014 | US20140030191 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof |
| 01/29/2014 | CN102112474B Quinuclidine carbonate derivatives and medicinal composition thereof |
| 01/23/2014 | US20140024673 (2s,3r)-n-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzyofurn-2-carboxamide, novel salt forms, and methods of use thereof |
| 01/22/2014 | EP2687527A1 Cinchona alkaloid derivatives, their process of preparation and their use as catalysts |