| Patents for C07D 451 - Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.02,4] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof (5,273) |
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| 09/09/2003 | US6617339 Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them |
| 09/03/2003 | EP1235826B1 Quinuclidine acrylamides |
| 08/28/2003 | US20030162972 Pyridyl alkane acid amides as cytostatics and immunosupressives |
| 08/27/2003 | EP1337532A2 Compound for chelating a metal, radiopharmaceutical, manufacturing process therefor, and diagnostic kit |
| 08/27/2003 | EP1007520B1 2-aminopyridines containing fused ring substituents as nos inhibitors |
| 08/27/2003 | EP0874809B1 Carbamoyloxy derivatives of mutiline and their use as antibacterials |
| 08/26/2003 | US6610849 Process for the manufacture of tropenol |
| 08/21/2003 | WO2003068235A1 Nicotinamide derivatives useful as pde4 inhibitors |
| 08/21/2003 | WO2003068234A1 Nicotinamide derivatives and a tiotropium salt in combination for the treatment of e.g. inflammatory, allergic and respiratory diseases |
| 08/21/2003 | WO2003068233A1 Nicotinamide derivatives and a tiotropium salt in combination for the treatment of e.g. inflammatory, allergic and respiratory diseases |
| 08/21/2003 | WO2003068232A1 Nicotinamide derivatives useful as pde4 inhibitors |
| 08/21/2003 | WO2003068220A1 1-arylsulfonyl-3-substituted indole and indoline derivatives useful in the treatment of central nervous system disorders |
| 08/21/2003 | US20030158221 2-imidazomethyl- pyrido(4,3-b)indol-1-one or -carbazol-1-one derivatives containing an ester group; especially for treating irritable bowel syndrome. |
| 08/21/2003 | CA2475708A1 Nicotinamide derivatives useful as pde4 inhibitors |
| 08/20/2003 | EP1335729A2 Inhalative solution formulation containing a tiotropium salt |
| 08/20/2003 | CN1437599A Tryasolyl tropane derivatives for therapy |
| 08/19/2003 | US6608078 Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment |
| 08/19/2003 | US6608055 Crystalline anticholinergic, processes for preparing it and its use for preparing a pharmaceutical composition |
| 08/14/2003 | WO2003066004A2 Therapeutic compounds |
| 08/14/2003 | US20030153568 Serine/threonine and tyrosine kinases inhibitors |
| 08/14/2003 | CA2476218A1 Therapeutic compounds |
| 08/13/2003 | EP1334092A1 Process for preparation of bicyclic and polycyclic molecules |
| 08/13/2003 | EP1333830A2 Novel medicament compositions based on anticholinergics and corticosteroids |
| 08/12/2003 | US6605621 Monomeric and dimeric heterocycles, and therapeutic uses thereof |
| 08/12/2003 | CA2088702C Aminobenzoic acid derivatives |
| 08/07/2003 | WO2003064432A1 Process for total synthesis of ecteinascidins and intermediates therefor |
| 08/07/2003 | WO2003064419A1 Novel fluorene carboxylic acid esters, methods for the production thereof, and use of the same as pharmaceuticals |
| 08/07/2003 | WO2003064418A1 Anticholinergic agents, method for producing the same and use thereof as medicaments |
| 08/07/2003 | WO2003064417A1 Xanthene-carboxylic acid esters of tropenol and scopine as m3 antagonists, method for producing the same and use thereof as medicaments |
| 08/07/2003 | US20030149017 For therapy and prophylaxis of migraine, inflammatory diseases, stroke, acute and chronic pain, hypovolemic shock, traumatic shock, reperfusion injury, Crohn's disease, ulcerative colitis, septic shock, multiple sclerosis, etc. |
| 08/05/2003 | US6602875 Sorbitol dehydrogenase inhibitors |
| 07/31/2003 | WO2003062235A1 Modulators of acetylcholine receptors |
| 07/31/2003 | WO2003061657A1 5-ht3 receptor antagonists and methods of use |
| 07/31/2003 | US20030144319 2-Substituted piperidine analogs as excitatory amino acid receptor antagonists that block N-methyl-D-aspartic acid receptors; neuroprotective agents; stroke; brain disorders; antiischemic agents; anxiolytic agents; headaches; analgesics |
| 07/31/2003 | US20030144317 Ester interchange effected by heating benzoylmethylecgonine and 1,2-propylene glycol in the presence/absence of water followed by removal of water to obtain 2% 2-hydroxypropyl benzoylecgonine esters and 2 % ecgonidine esters; stability |
| 07/31/2003 | US20030144289 Dopamine and serotonin reuptake antagonists, used for the prophylaxis of drug abuse or dependence, neurodegenerative diseases or as antidepressants |
| 07/31/2003 | US20030144263 Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them |
| 07/31/2003 | CA2473392A1 5-ht3 receptor antagonists and methods of use |
| 07/29/2003 | CA2132982C Catalytic antibodies against cocaine and methods of using and producing same |
| 07/29/2003 | CA2089070C Cocaine receptor binding ligands |
| 07/23/2003 | EP1328524A2 Novel anticholinergics, method for the production thereof and use thereof as medicaments |
| 07/23/2003 | CN1432011A Benzoamide piperidine compounds as substance P antagonists |
| 07/22/2003 | US6596868 Process for synthesizing anhydroecgonine derivative |
| 07/17/2003 | WO2003057694A1 Method for producing scopine esters |
| 07/17/2003 | WO2003057672A2 Tetrahydroquinoline analogues as muscarinic agonists |
| 07/16/2003 | EP1326867A2 Bridged piperazine derivatives |
| 07/16/2003 | EP1326862A1 Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament |
| 07/16/2003 | EP1326585A2 Method for producing powdery formulations |
| 07/10/2003 | WO2003055879A2 Tropane derivative, chelation product comprising this tropane derivative and a metal or a metal complex, and radiopharmaceutical |
| 07/10/2003 | US20030130513 Useful for treating depression, anxiety, and alleviating the symptoms caused by withdrawal or partial withdrawal from tobacco or nicotine. |
| 07/10/2003 | US20030130236 Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs |
| 07/10/2003 | US20030129591 Linker arms for nanocrystals and compounds thereof |
| 07/10/2003 | US20030129590 Linker arms for nanocrystals and compounds thereof |
| 07/09/2003 | EP1325001A1 Anticholinergic agents that can be used as medicaments and method for the production thereof |
| 07/09/2003 | CN1113880C Process for production of endotropine |
| 07/03/2003 | WO2002016340A8 Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same |
| 07/03/2003 | US20030125350 Combination of formoterol and a tiotropium salt |
| 07/02/2003 | EP1224180B1 Substituted azoles |
| 07/02/2003 | EP1218372B1 Novel heterocyclic compounds useful as reversible inhibitors of cysteine proteases |
| 07/01/2003 | US6586446 Chemotaxic cytokine agonists or antagonists such as N(3-acetylphlenyl)-N'-(-2-((-3-((4-fluorophenyl)methyl)-8 -azabicyclo(3.2.1)oct-8-yl)methyl)-(2R)-1-cyclohexyl)urea, used as antiinflammatory agents for asthma or allergies |
| 07/01/2003 | US6586430 Administering azabicyclo compounds to treat human immunodeficiency virus infections and respiratory system disorders |
| 07/01/2003 | US6585959 Excipient having different particle size distribution are added in alternate layers into a suitable mixing vessel; mixing together using a suitable mixer, wherein a portion of the excipient having the larger particle size is added first |
| 06/26/2003 | US20030119847 Heteroaryl derivatives as superior ligands for nociceptin receptor ORL-1 |
| 06/25/2003 | EP0777652B1 Neuroprotective 3-(piperidinyl-1)-chroman-4,7-diol and 1-(4-hydrophenyl)-2-(piperidinyl-1)-alkanol derivatives |
| 06/25/2003 | CN1426411A 3-(diarylmethylene)-8-azabicyclo [3,2,1] octane derivatives |
| 06/25/2003 | CN1112365C Piperidine derivatives and preparing method and use |
| 06/19/2003 | WO2003028650A3 Benzimidazolidinone derivatives as muscarinic agents |
| 06/18/2003 | EP1318978A2 N-acylsulfonamide apoptosis promoters |
| 06/17/2003 | US6579878 Pharmaceutical compositions and methods for use |
| 06/17/2003 | US6579874 Substituted azoles |
| 06/17/2003 | US6579863 Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
| 06/12/2003 | US20030109708 Process for synthesizing anhydroecgonine derivative |
| 06/12/2003 | US20030109564 Treating: allergy, allergy-induced airway responses, congestion, hypotension, cardiovascular disease, hypotension, diseases of the GI tract, hyper and hypo motility and acidic secretion of the gastrointestinal tract, obesity, sleep |
| 06/11/2003 | CN1423651A New use and novel N-azabicyclo-amide derivatives |
| 06/05/2003 | WO2003045388A1 Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases |
| 06/05/2003 | US20030105125 Tropane analogs and methods for inhibition of monoamine transport |
| 06/05/2003 | US20030105096 Serotonin transport inhibitors |
| 06/05/2003 | US20030105074 Phthalazine compounds and therapeutic agents for erectile dysfunction |
| 06/04/2003 | EP1315710A1 Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same |
| 06/04/2003 | EP1315709A1 Aminoalkylbenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same |
| 06/04/2003 | CN1422262A 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors |
| 06/03/2003 | US6573275 Insecticidal compositions comprising and to methods of combatting and controlling insect pests therewith. |
| 05/29/2003 | US20030100545 Psychological disorder treatments that increase the activity of cholinergic receptors |
| 05/28/2003 | CN1420881A Beta-amino acid derivs. as inhibitors of matrix metalloproteases and TNF-alpha |
| 05/22/2003 | WO2003042209A1 Novel benzoylecgonine compositions and methods for producing them |
| 05/22/2003 | WO2003042176A1 Azabicyclo compound, matrix metalloprotease inhibitor, and skin preparation |
| 05/22/2003 | US20030096858 The parent drug compound is modified by forming one or more of predetermined chemical arrangement within parent drug structure for programming specific course and rate of metabolism for drug that leads to inactive nontoxic metabolite |
| 05/22/2003 | US20030095992 Altering a drug's distribution, metabolism and elimination properties, especially by modifying with aralkyl ester moieties to increase rate of metabolism to inactive and nontoxic metabolites when exposure is halted; surgery, riots |
| 05/22/2003 | CA2466062A1 Novel benzoylecgonine compositions and methods for producing them |
| 05/20/2003 | US6566084 Detecting hydrolysis of cocaine compound; obtain cocaine mixture, incubate with antibody, monitor generation of benzoic zacid |
| 05/15/2003 | WO2003039469A2 Heteroaryl derivatives as superior ligands for nociceptin receptor orl-1 |
| 05/15/2003 | US20030092729 Anticancer agents; modulating glycoprotein |
| 05/15/2003 | US20030092712 Antiinflammatory agents; rheumatic diseases |
| 05/14/2003 | EP1309551A1 Indoline derivatives as 5ht2c antagonists |
| 05/13/2003 | CA2115443C Azabicyclo arylacetylene and arylenyne oximes as cholinergic agents and methods of treatment |
| 05/08/2003 | US20030087927 Crystalline anticholinergic, processes for preparing it and its use for preparing a pharmaceutical composition |
| 05/07/2003 | EP1307449A1 1,4-dihydropyridines as bradykinin antagonists |
| 05/02/2003 | EP1305316A2 Azabicyclic derivatives and their therapeutic use |
| 05/02/2003 | EP1212103A4 4-fluoroalkyl-3-halophenyl nortropanes |
| 04/29/2003 | US6555552 Azabicyclic amine derivatives and their use as therapeutic agents |