Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
06/2005
06/08/2005EP1538216A1 Process for producing optically active erythro 3-cyclohexylserines
06/08/2005EP0794251B1 D-pantolactone hydrolase and gene encoding the same
06/07/2005US6902927 Separation of enantiomers of an amino acid; obtain racemic mixture, incubate with glutaric anhydride, expose products to hydrolase, recover enantiomers
06/02/2005WO2005049816A2 Oxidoreductase from metschnikowia zobellii
06/02/2005US20050119307 Method of treating attention deficit disorders with D-threo methylphenidate
06/01/2005EP1536017A2 Process for producing optically active octahydro-1H-indole-2-carboxylic acid
06/01/2005EP1534849A2 Use of malate dehydrogenase for nadh regeneration
06/01/2005CN1622932A Resolution of chiral compounds using aminocyclopentadienyl ruthenium catalysts
06/01/2005CN1204262C Method for producing optically active amines
05/2005
05/25/2005EP1532146A2 A method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives
05/24/2005US6897058 Method for the preparation of enantiomerically enriched amines
05/19/2005WO2005044973A2 NOVEL ACETOACETYL-CoA REDUCTASE AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL
05/19/2005WO2004094452A3 Macrocyclic isoquinoline peptide inhibitors of hepatitis c virus
05/19/2005US20050106692 Reacting an allene derivative containing two hydroxy or two ester groups in presence of esterase or lipase enzyme catalyst with an unsaturated ester when ( both are hydroxy groups) or with water when (both are ester groups); chemical intermediates for medicinal and agricultural active agents
05/19/2005US20050106690 Process for producing optically active octahydro-1H-indole-2-carboxylic acid
05/18/2005EP1196622B1 The use of orthoesters for the synthesis of chiral acids in biocatalyzed irreversible esterification processes
05/18/2005CN1617931A Esteralse with lipase activity
05/17/2005US6894170 Process for the preparation of substituted thiazolines and their intermediates
05/12/2005WO2005005633A3 Methods for the stereoselective synthesis and enantiomeric enrichment of b-amino acids
05/12/2005US20050101782 Process for the preparation of substituted thiazolines and their intermediates
05/11/2005EP1075534B1 Improvements in the enzymatic synthesis of chiral amines
05/11/2005EP1036190B1 A method for producing hydroxycarboxylic acids by auto-degradation of polyhydroxyalkanoates
05/10/2005US6890748 Production of lysosomal enzymes in plants by transient expression
05/10/2005CA2001515C Process for preparing optically active glycidate esters
05/06/2005WO2005040076A1 Process for the preparatin of alkynols
05/03/2005US6887700 Process for the enzymatic preparation of enantiopure 1, 3-dioxolan-4-one and 1,3-oxathiolan-5-one derivatives
05/03/2005US6887697 D-aminoacylase and gene encoding the same
05/03/2005US6887696 Production of lysosomal enzymes in plants by transient expression
04/2005
04/28/2005WO2005038036A1 Method for transforming epoxy carrier of trifluoromethyl groups
04/28/2005US20050090432 Macrocyclic isoquinoline peptide inhibitors of Hepatitis C virus
04/27/2005EP0983367B1 Enantioselective epoxide hydrolases and genes encoding these
04/26/2005CA2360376C Novel carbonyl reductase, gene thereof and method of using the same
04/21/2005US20050084946 E.g., 5-indolyl methyl hydantoin, 5-(p-hydroxybenzyl) hydantoin, 5-isobutyl hydantoin, and 5-(3'-pyridyl)-methyl hydantoin; efficiently catalyzes racemization reactions at a high optimum temperature
04/20/2005EP1483229A4 Resolution of chiral compounds using aminocyclopentadienyl ruthenium catalysts
04/14/2005WO2005033076A1 Method for preparing 3-hydroxy-4-hydroxymethyl-pyrrolidine compounds
04/14/2005WO2004022764A9 Use of malate dehydrogenase for nadh regeneration
04/14/2005US20050079595 Expression vector comprising nucleotide sequences coding hydrolase for use in generating enantimorphic carboxylic acid; agrochemicals and pharmeceuticals; drug design
04/14/2005DE10336270B3 Verfahren zur enantioselektiven Herstellung von sekundären Alkoholen durch lipasenkatalysierte Solvolyse der korrespondierenden Acetessigester Method for the enantioselective preparation of secondary alcohols by lipasenkatalysierte solvolysis of the corresponding ethyl acetoacetate
04/13/2005CN1196795C Novel method for preparing synthesis intermediates
04/12/2005US6878842 Process for the enantioselective synthesis of propargyl alcohol derivatives of R configuration from the racemic mixtures thereof
03/2005
03/30/2005EP1115881B1 Process for the enzymatic kinetic resolution of 3-phenylglycidates by transesterification with aminoalcohols
03/30/2005CN1194960C Method for preparing 4,5-diamino shikimic acid derivative
03/24/2005WO2005026373A1 Enzymatic synthesis of enatiopure intermediates by means of cholesterolesterase from yeasts
03/24/2005WO2005026338A1 Alcohol dehydrogenases with increased solvent and temperature stability
03/24/2005WO2005026110A1 Optically active 3,3'-dithiobis(2-amino-2­methylpropionic acid) derivative and process for producing optically active 2-amino-3-mercapto-2-methyl­propionic acid derivative
03/24/2005WO2004016767A3 Evolving new molecular function
03/24/2005US20050065204 Process for the preparation of enantiopure pyrrolidin-2-one derivatives
03/24/2005US20050064570 Whole cell catalyst which expresses lactobacillus oxidase for use in generating/producing chrial enantiomer-enriched organic compounds
03/24/2005CA2539037A1 Enzymatic synthesis of enatiopure intermediates by means of cholesterolesterase from yeasts
03/24/2005CA2535710A1 Alcohol dehydrogenases with increased solvent and temperature stability
03/23/2005EP1152054B1 Novel carbonyl reductase, gene thereof and method of using the same
03/23/2005CN1599798A Process for producing D-alanine
03/23/2005CN1194098C Method for producing hydroxycarboxylic acids by auto-degradation of polyhydroxyalkanoates
03/22/2005US6869791 Method for sterilizing transformed cells
03/22/2005US6869788 DNA encoding novel D-aminoacylase and process for producing D-amino acid by using the same
03/22/2005US6869783 Nucleic acid sequences which code for a polypeptide having nitrilase activity, nucleic acid constructs comprising the nucleic acid sequences, and vectors comprising the nucleic acid sequences or the nucleic constructs
03/22/2005US6869781 Process for the enzymatic preparation of enantiomer-enriched β-amino acids
03/17/2005WO2004090094A3 L-carnitin dehydrogenases, their derivatives and method for producing substituted (s) alkanols
03/17/2005WO2003083126A8 Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates
03/17/2005DE10337614A1 Verfahren zur Herstellung von D-Aminosäuren A process for the preparation of D-amino acids
03/17/2005DE102004022065A1 Screeningverfahren für Hydantoinrazemasen Screening process for hydantoin racemases
03/16/2005EP1513946A1 POLYPEPTIDES HAVING a- H-a-AMINO ACID AMIDE RACEMASE ACTIVITY AND NUCLEIC ACIDS ENCODING THE SAME
03/16/2005EP0904400B1 Enzymatic process for stereoselective preparation of therapeutic amides
03/09/2005EP0978567B1 Process for producing optically active alcohols
03/09/2005CN1592789A Process for the preparation of an enantiomerically enriched alpha-amino acid
03/09/2005CN1592783A Sulphatases and use thereof
03/03/2005US20050049279 Sustained release daily dosage form comprising D-threo methylphenidate; substantially free of L-threo and erythro optical isomers; minimizing side effects, increasing efficacy
03/02/2005EP1232279B1 Method for producing optically active amines
03/02/2005EP1151130B1 Coenzyme useful for the synthesis of l-carnitine
03/02/2005CN1191373C Enzyme resolution process for prepairng chiral-trands-chrysanthemum monocarboxylic acid
03/02/2005CN1191372C Resolution of trans-2-(alkoxycarbonylethyl)-laitams useful in synthesis of 1-(4-fluorphenyl)-3(R)-[3(S)-hydroxy-3-(flurophenyl)-propyl)]-4(S)-(4-hydroxyphenyl)-2-azetidinone
02/2005
02/24/2005WO2005017171A2 Process for the production of d-amino acids
02/24/2005WO2005016901A1 Trans-1(6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine
02/24/2005WO2005016900A1 Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament
02/24/2005CA2536073A1 Trans-1(6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine
02/23/2005EP1508565A1 Process for the preparation of optically active aminoalcohols
02/17/2005WO2005014509A1 Process for the preparation of enantiomerically enriched esters and alcohols
02/17/2005US20050038255 Stereoselective preparation of cyclic l-amino acids
02/16/2005EP1506294A1 Hydantoin racemase
02/16/2005EP1506177A2 Process for the preparation of the enantiomeric forms of 2-substituted 2-(2,5-dioxoimidazolidin-1-yl)-acetic acid derivatives
02/16/2005CN1580275A Preparation method for resolving optical active cyan alcohol by enzyme process
02/16/2005CN1189569C Method for producing optically active 1-amino-4-hydroxymethyl-cyclopent-2-ene derivatives
02/15/2005CA2117482C New ketonic ester reductases, its preparation and use for enzymatic redox reactions
02/10/2005US20050032182 Process for the enantioselective preparation of secondary alcohols by lipase-catalyzed solvolysis of the corresponding acetoacetic esters
02/09/2005EP1505156A1 Process for the enantioselective preparation of secondary alcohols by lipase catalysed solvolysis of the corresponding acetoacetic acid ester
02/03/2005WO2004087940A3 PROCESS FOR PRODUCING ENANTIOPURE β-AMINO ACID DERIVATIVES, AND ENANTIOPURE β-AMINO ACID DERIVATIVES
02/03/2005US20050026260 Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates
02/02/2005EP1502914A1 Process for the preparation of 1-amino-4-(hydroxymethyl)-2-cyclopentene derivatives
02/02/2005EP1501780A1 Process for the enantioselective synthesis of propargyl alcohol derivatives of r configuration from the racemic mixtures thereof
02/02/2005CN1187444C Enzyme with deaminizating formyl activity
01/2005
01/27/2005WO2004097026B1 The enzymatic method of making 1,2-diol derivatives and their esters
01/27/2005WO2004081220A3 A process for enzymatically resolving an enantiomeric mixture of alpha-hydroxy acids
01/26/2005EP1499716A1 Adh from rhodococcus erythropolis
01/25/2005US6846968 Production of lysosomal enzymes in plants by transient expression
01/25/2005US6846654 Catalytic antibodies as chemical sensors
01/20/2005WO2005005633A2 Methods for the stereoselective synthesis and enantiomeric enrichment of b-amino acids
01/20/2005WO2004085651A3 Pantolactone hydrolase
01/20/2005CA2529509A1 Methods for the stereoselective synthesis and enantiomeric enrichment of .beta.-amino acids
01/13/2005WO2004087932A3 Enzymatic resolution of (±) methyl trans-3-phenyl glycidate
01/13/2005US20050009158 Process for enzymatically resolving an enantiomeric mixture of alpha-hydroxy acids
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