Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
10/2005
10/27/2005CA2564130A1 Methods for obtaining optically active epoxides and vicinal diols from 2,2-disubstituted epoxides
10/27/2005CA2564119A1 Methods of obtaining optically active epoxides and vicinal diols from styrene oxides
10/26/2005EP1587943A1 Method for preparing a (r)- or (s)- form of n-(2,6-dimethyl phenyl) alanine and a counter enantiomeric form of n-(2,6-dimethyl phenyl) alanine ester thereto using enzyme
10/26/2005EP1587937A1 Process for preparing enantiomerically enriched (1s,4r) 1-acetoxy-4-hydroxycyclopent-2-ene
10/26/2005CN1224697C Process for preparation of amino alcohols and derivatives thereof
10/25/2005US6958233 Generating S-adenosyl-L-methionine; obtain yeast, incubate in nutrient broth, lyse, filter, elute and recover s-adenosyl-l-methionine
10/20/2005WO2005098018A1 Chemo-enzymatic process for preparing escitalopram
10/20/2005CA2561888A1 Chemo-enzymatic process for preparing escitalopram
10/19/2005EP1586636A1 Hydantoinase variants with improved properties and their use for the production of amino acids
10/18/2005CA2104399C Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane
10/13/2005WO2005095629A1 Process for the preparation of enantiomerically enriched esters and alcohols by means of azeotropically dried enzyme compositions
10/13/2005WO2005095628A1 Method for the production of chiral, secondary alcohols
10/13/2005WO2005095602A1 Novel modified s-hydroxynitrile lyase
10/12/2005EP1584690A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE a-METHYLCYSTEINE DERIVATIVE
10/12/2005EP1001772B1 Improved delivery of multiple doses of medications
10/12/2005CN1681936A Process for producing optically active erythro 3-cyclohexylserines
10/11/2005US6953678 Use of orthoesters for the synthesis of chiral acids in biocatalyzed irreversible esterification processes
10/11/2005US6953677 Biosynthesis of L-methionine, L-tryptophan, L-phenylalanine, or L-tyrosine, by fermenting an E. coli host cell with a polynucleotide sequences in presence of an immobilized hydrolase enzyme
10/06/2005WO2005093081A1 Process for preparing optically active amino acids using a whole-cell catalyst
10/06/2005DE10361794B3 Optisch aktive heteroaromatische ß-Hydroxy-Ester und Verfahren zu deren Herstellung sowie deren Verwendung als Zwischenprodukte bei der Epothilon-Totalsynthese Optically active heteroaromatic beta-hydroxy ester, and processes for their preparation and their use as intermediates in the total synthesis of epothilone-
10/06/2005CA2559186A1 Process for preparing optically active amino acids using a whole-cell catalyst
10/05/2005EP1581465A2 Biocatalytic preparation of enantiomerically enriched aminopentanenitrile
09/2005
09/29/2005US20050215518 Glycosaminoglycans derived from K5 polysaccharide having high anticoagulant and antithrombotic activities and process for their preparation
09/28/2005EP1578987A2 Epoxide hydrolases, nucleic acids encoding them and methods for making and using them
09/28/2005EP1578910A2 Nitrilases
09/28/2005CN1675371A Polypeptides having a- h-a-amino acid amide racemase activity and nucleic acids encoding the same
09/21/2005EP1576194A1 Bacterial strains of delftia acidovorans mc1-r, their production and their use in the production of the r enantiomers of 2-phenoxypropionic acid derivatives
09/21/2005EP1576147A1 Bacterial strains delftia acidovorans mc1-s, production and use thereof for the production of the s enantiomers of 2-phenoxypropionic acid derivatives
09/21/2005EP1576108A2 Nitrilases, nucleic acids encoding them and methods for making and using them
09/21/2005CN1671704A A method of preparing enantiomers of indole-2, 3-dione-3-oxime derivatives
09/20/2005US6946272 Transition state analogs
09/15/2005WO2005085462A1 Enzymatic preparation of an enantiomerically enriched beta-2-amino acids
09/15/2005WO2005085184A1 Process for production of cyclopentenenitrile derivatives
09/15/2005WO2002085519A3 High capacity methods for separation, purification, concentration, immobilization and synthesis of compounds and applications based thereupon
09/15/2005US20050204422 Using vector transformation to express antisense sequences which suppress phytoene desaturase activity and enhance phytoene concentration in plant
09/14/2005EP1573019A1 Stereoselective process for the production of dioxolane nucleoside analogues
09/14/2005EP1573018A1 Chemoenzymatic process for stereoselective preparation of r- and s-enantiomers of 2-hydroxy-3-(2-thienyl) propanenitrile
09/14/2005EP1572363A2 High capacity methods for separation, purification, concentration, immobilization and synthesis of compounds and applications based thereupon
09/07/2005EP1570059A1 Method for the production of r-alpha-lipoic acid by fermentation
09/01/2005US20050192441 Methods for the preparation of stereoisomerically enriched amines
08/2005
08/31/2005EP1568778A1 Hydantoinase from agrobacterium
08/31/2005EP1568679A1 Process for producing optically active 3-hydroxypropionic ester derivative
08/31/2005CN1661025A Production of levodione by microorganism
08/30/2005US6936445 Comprises hydrolase for N-benzylazetidine-2-carboxylic acid ester immolbilized on poroous divinylbenzene-styrene copolymer
08/18/2005WO2005075650A1 Polypeptide having amidase activity and gene thereof
08/18/2005US20050181472 proteins from Pseudomonas, having butynol I esterase activity; nucleotides sequences codes; expression cassettes, vectors and genetic engineered microorganisms; used for stereospecific hydrolysis or transesterification of organic esters
08/17/2005EP0857790B1 Process for producing optically active amino compounds
08/17/2005CN1656230A Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates
08/17/2005CN1656218A Hydantoin racemase
08/16/2005US6930130 For use in therapy of schizophrenia, Parkinson's disease, and Alzheimer's disease
08/11/2005US20050176119 Process for the preparation of 1-(3-trifluoromehylphenyl) -propan-2-ol enantiomers
08/11/2005US20050176118 Esterases with lipase activity
08/11/2005DE19937825B4 Verfahren zur Reduktion von Hydroxyketo-Carbonsäuren und deren Estern A method of reducing Hydroxyketo-carboxylic acids and esters thereof
08/04/2005WO2004104205A3 Enzymatic preparation of chiral indole esters
08/04/2005US20050170473 Hydrolyzing with hydrolase (protease, esterase, lipase from Candida antarctica)
08/04/2005US20050170376 Combinatorial chemistry
07/2005
07/28/2005WO2001032847A9 Novel esterases derived from pseudomonas aeruginosa, its gene and process for production of optically active carboxylic acids using them
07/27/2005CN1644012A Serration and its use in preparation of chiral precurser for dielzepin
07/27/2005CN1212405C Enzyme method resolution method of racemic ornidazole
07/27/2005CN1212403C Method for preparing optical pure phenylethanediol by utilizing microbial stereoselectivity transformation and its special-purpose microbe
07/20/2005CN1643158A Process for preparing optically active beta-aminocarboxylic acids from racemic N-acylated beta-aminocarboxylic acids
07/14/2005WO2005064006A1 OPTICALLY ACTIVE, HETEROAROMATIC β-HYDROXY ESTERS, PROCESSES FOR THEIR PREPARATION FROM β-KETO ESTERS AND PROCESSES FOR THE PREPARATION OF THESE β-KETO ESTERS
07/14/2005US20050153409 Stereoselectively resolving a racemic mixture of 3-chloro-2-methyl-1,2-propanediol enantiomorphs by allowing at least one kind of microorganism (especially Pseudomonas) to act on it; process is enhanced by conducting it under aerobic conditions
07/14/2005US20050153404 Anti-kazlauskas lipases
07/14/2005US20050153401 Process for preparing optically active beta-aminocarboxylic acids from racemic n-acylated beta-aminocarboxylic acids
07/14/2005CA2546981A1 Optically active, heteroaromatic .beta.-hydroxy esters, processes for their preparation from .beta.-keto esters and processes for the preparation of these .beta.-keto esters
07/13/2005EP1553170A1 Novel carbonyl reductase, gene thereof and method of using the same
07/13/2005EP1373548B1 Chemo-enzymatic synthesis of optically enriched rose-oxides
07/13/2005CN1639344A A method of selectively producing male or female sterile plants
07/13/2005CN1639329A Selective enzymatic esterification and solvolysis of epimeric vitamin D analog and separation of the epimers
07/13/2005CN1210282C Vitamin D precursors, preparation and intermediates thereof
07/07/2005US20050150013 Generating sex specific sterility in plants via vector transformation and expression of phytotoxic converting enzymes; hybrid seed production and enhanced crop yields
07/06/2005EP1550730A1 Method for producing optically active 3-chloro-2-methyl-1,2-propanediol taking advantage of microorganism
07/06/2005EP1550725A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE alpha-METHYLCYSTEINE DERIVATIVE
07/06/2005EP1075534B8 Improvements in the enzymatic synthesis of chiral amines
07/06/2005CN1635129A Process for preparing optical active cyanalcohol through enzyme catalysis alcoholysis reaction resolution
06/2005
06/30/2005WO2005044973A3 NOVEL ACETOACETYL-CoA REDUCTASE AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL
06/30/2005US20050142646 Hydrolyzing an enantiomeric mixture of N-unprotected beta -amino acid esters with a hydrolase in a two-phase system of water and an organic solvent; optics efficiency; kinetics; industrial scale; environmental compatibility,
06/29/2005CN1633504A Method of preparing 3-[2-{(methylsulfonyl)oxy}ethoxy]-4-(triphenylmethoxy)-1-butanol, methane sulfonate
06/29/2005CN1633502A Process for producing (3r, 5s)-(e)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin- 3-yl]-3, 5-dihydroxyhept-6-enic acid esters
06/29/2005CN1633427A Method for preparing chiral amines
06/29/2005CN1632129A Method for enzyme catalytic resolution of N substituted alpha amino acid
06/28/2005CA2307390C Enzymatic resolution of aminotetralins
06/23/2005WO2005017171A3 Process for the production of d-amino acids
06/23/2005DE10354779A1 Oxidoreduktase aus Metschnikowia zobellii Oxidoreductase from Metschnikowia zobellii
06/22/2005EP1165763B1 Hydantoinase variants with improved properties and their use for the production of amino acids
06/21/2005US6908752 Generation of preferential particle; obtain chemical intermediates, inubate wit reaction mixture and enzyme, recover and separate preferential particles
06/16/2005WO2005054186A2 Methods for the preparation of stereoisomerically enriched amines
06/16/2005WO2004111227A3 Screening process for hydantoin racemases
06/16/2005WO2004106534B1 The enzymatic method of making 1,2-diol derivatives and their esters with succine anhydride
06/16/2005US20050130282 Resolution of chiral compounds using aminocyclopentadienyl ruthenium catalysts
06/16/2005US20050130141 Process for preparing variant polynucleotides
06/16/2005US20050130140 Using site directed mutagenesis and polymerase chain reaction replication to produce polypeptides of preferential characteristics; directed protein evolution
06/16/2005CA2549289A1 Methods for the preparation of stereoisomerically enriched amines
06/15/2005EP1541692A1 PROCESS FOR PRODUCING L-a-METHYLCYSTEINE DERIVATIVE
06/15/2005EP1541147A1 Improved delivery of multiple doses of a methylphenidate drug
06/15/2005EP1540013A2 Evolving new molecular function
06/14/2005US6905861 Extracted from fungi; polypeptide
06/09/2005US20050125859 Modified galactosidase for use as tool in enzyme replacement therapy and treatment of lysosomal storage diseases in humans and animals
06/09/2005US20050123991 Nucleotide sequences coding hydrolase capable of resolving enantiomeric mixtures of alcohol or ester substrates; for use in regio-and stereoselective biotransformations
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