Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
08/2006
08/03/2006WO2006080409A1 5-substituted hydantoin racemase, dna encoding the same, recombinant dna, transformed cell, and process for production of optically active n-carbamylamino acid or optically active amino acid
08/03/2006US20060172393 Process for producing optically active alpha -methylcysteine derivative
08/02/2006EP1686114A1 Process for producing optically active 2-alkylcysteine, derivative thereof, and processes for production
08/02/2006EP1685248A2 Oxidoreductase from metschnikowia zobellii
08/02/2006EP1341927B1 Method of preparing 3-¬2-{(methylsulfonyl)oxy}ethoxy|-4-(triphenylmethoxy)-1-butanol, methane sulfonate
08/02/2006CN1267560C Process for preparing stereoisomer carboxylate
08/01/2006CA2346426C Enzymatic resolution of selective estrogen receptor modulators
07/2006
07/27/2006US20060166342 via enzyme from Brettanomyces, Debaryomyces, Galactomyces, Ogataea, Pichia, Saccharomycopsis, Sporidiobolus, Sporobolomyces, Sterigmatomyces, Torulaspora, Trichosporon, Yamadazyma, Achromobacter, Cellulomonas, Devosia, Hafnia, Jensenia, Klebsiella, Micrococcus, Proteus, or Serratia
07/27/2006US20060166337 Process for producing optically active erythro 3-cyclohexylserines
07/26/2006CN1809642A Method for the microbiological isomerisation of alpha-hydroxy carboxylic acids
07/26/2006CN1807403A Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use
07/26/2006CN1266148C Method for producing 2-azetidinone derivative
07/20/2006WO2006076565A2 Preparation of chiral propargylic alcohol and ester intermediates of himbacine analogs
07/20/2006WO2006034812A3 Method for producing an optically active 2-methyl-alkane-1-ol from the corresponding 2-methylalk-2-en-1-al, comprising carbonyl-selective reduction, enantioselective hydration and lipase-catalyzed, stereoselective acylation in order to enrich the desired enantiomer
07/20/2006CA2594742A1 Preparation of chiral propargylic alcohol and ester intermediates of himbacine analogs
07/18/2006US7078226 Method for producing optically active amines
07/13/2006WO2006015727A3 Method for enantioselectively opening 3-substituted oxetan-2-ones under the action of lipases of candida antarctica or burkholderia plantarrii
07/12/2006CN1800401A Ester hydrolase and its gene and recombinant enzyme
07/11/2006US7074606 Microorganism utilizing propionamide for use in preparation of therapeutic amides
06/2006
06/29/2006US20060141606 lipase-mediated kinetic resolution of racemic 3-hydroxy-4-trityloxybutanenitrile; acetylation; transesterification
06/29/2006US20060141591 Method for producing optically active chroman-carboxylate
06/28/2006EP1673463A1 Method for transforming epoxy carrier of trifluoromethyl groups
06/28/2006EP1673327A1 Process for the preparation of alkynols
06/28/2006EP1540013A4 Evolving new molecular function
06/28/2006EP1332221B1 Enzyme catalysis in the presence of ionic liquids
06/27/2006US7067305 Enzymatic process for the resolution for enantiomeric mixtures of β-lactams
06/27/2006US7067291 Biocatalytic preparation of enantiomerically enriched aminopentanenitrile
06/22/2006WO2006064213A2 Chemical process
06/22/2006WO2006015716A3 Method for producing the enantiomer forms of cis-configured 3-hydroxycyclohexane carboxylic acid derivatives using hydrolases
06/22/2006US20060134763 Stereoselective process for the production of dioxolane nucleoside analogues
06/22/2006CA2588591A1 Chemical process
06/20/2006US7063977 Enzymatic resolution of t-butyl taxane derivatives
06/15/2006US20060127997 Process for the preparation of compounds with enhanced optical purity
06/14/2006EP1141333B1 Process for the enzymatic preparation of amino acid derivatives with enhanced optical purity
06/14/2006DE102004059469A1 Preparation of optically active trans-1,2-cyclopropane dicarbonic acid-diester and -monoester comprises enantioselective hydrolysis of a racemic mixture of trans-1,2-cyclopropane dicarbonic acid diesters enzymatically with esterase
06/14/2006CN1259306C Process for the preparation of aminoalcohol, aminoalcohol derivatives and their further conversion to (1S, 4R)-4-(2-AMINO - 6-CHLORO - 9- H - PURINE - 9-YL)-2- CYCLOPENTENYL-1-METHANOL or its salt
06/13/2006US7060485 DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, recombinant DNA containing the genes, cells transformed with the recombinant DNA, methods for producing proteins utilizing the transformed cells and methods for producing D-amino acids
06/13/2006US7060477 Protein corresponding to recombinant fungal epoxide hydrolase; use making enantiomerically pure diols and/or epoxides
06/13/2006US7060471 Stereoselective chemoenzymatic process for the preparation of optically enriched phenylglycidates as precursors of taxol side chain
06/08/2006WO2006058595A1 Enzyme reactions in miniemulsions
06/08/2006US20060122429 Preparation of optically active amines
06/08/2006CA2589939A1 Enzyme reactions in miniemulsions
06/07/2006EP1666458A1 Optically active 3,3 -dithiobis(2-amino-2-methylpropioni c acid) derivative and process for producing optically active 2-amino-3-mercapto-2-methyl-propionic acid derivative
06/07/2006EP1664323A1 Enzymatic synthesis of enatiopure intermediates by means of cholesterolesterase from yeasts
06/07/2006EP1664286A1 Alcohol dehydrogenases with increased solvent and temperature stability
06/07/2006CN1782088A Enzyme method for preparing laevo-rotation and dextro-rotation tryptophane 15N by resolving racemic tryptophase 15N
06/07/2006CN1258597C Method for preparing L-menthol
06/01/2006US20060115883 Regioselective hydrolysis of (E)-2-methyl-2-butenonitrile to (E)-2-methyl-2-butenoic acid (2M2BA) using enzyme catalysts having either a nitrilase activity or both of nitrile hydratase and amidase activities
06/01/2006DE10308350B4 Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 1,3-Cyclohexandiol-Derivaten A process for preparing the enantiomeric forms of cis-configured 1,3-cyclohexanediol derivatives
06/01/2006DE102004057966A1 Method for asymmetrical enzymatic production of optically active organic compounds in microemulsion
05/2006
05/31/2006EP1576194B1 Bacterial strains of delftia acidovorans mc1-r, their production and their use in the production of the r enantiomers of 2-phenoxypropionic acid derivatives
05/31/2006EP1342788B1 Process for producing optically active (4r)-1,3-tiazolidine-4-carboxylic acid
05/30/2006US7053225 Such as 2-(t-butyldimethylsilyloxymethyl)-3,4-((dimethylmethylene)-dioxy)-5-hydroxy -tricyclo(5.2.1.02,6) deca-3,8-diene; for Diels-Alder reaction; antitumor agents
05/30/2006US7053224 Intermediates and improved processes for the preparation of neplanocin A
05/26/2006WO2006055528A2 Process for the preparation of an optically acitive n-carbamate protected beta-lactam by optical resolution employing a candida antarctica lipase
05/26/2006WO2006054437A1 Method for preparing optically active compound
05/26/2006WO2006053713A1 Method for the production of optically-active alcohols
05/26/2006CA2580151A1 Stereoisomerically enriched .beta.-lactams using candida antarctica
05/24/2006EP1658277A1 Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament
05/24/2006EP1658276A1 Trans-1(6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine
05/24/2006EP1576147B1 Bacterial strains delftia acidovorans mc1-s, production and use thereof for the production of the s enantiomers of 2-phenoxypropionic acid derivatives
05/24/2006EP1290209A4 Method for preparing an r- or s-form of alpha-substituted heterocyclic carboxylic acid and a counter enantiomeric form of alpha-substituted heterocyclic carboxylic acid ester thereto using enzyme
05/24/2006EP1290208A4 Method for optically resolving a racemic alpha-substituted heterocyclic carboxylic acid using enzyme
05/24/2006CN1775951A Enzymatic deprotection of amines and hydroxides
05/18/2006US20060105435 Process for producing optically active alpha-methylcysteine derivative
05/18/2006DE102004062894B3 Addition of caffeine to cell suspension in production of chiral beta-hydroxy esters by stereoselective microbial reduction of prochiraler alpha substituted beta-ketoester using whole-cell biotransformation, increases diastereoselectivity
05/17/2006EP1657243A1 Procedure for the production of amino alcohols
05/17/2006EP1656456A1 Method of separating optical isomers of a protected aminoacid
05/17/2006EP1141373B1 Method for the enantioselective and regioselective reduction of 3,5-dioxocarboxylic acids, their salts and their esters
05/17/2006CN1774509A Biocatalytic preparation of enantiomerically enriched aminopentanenitrile
05/16/2006US7045341 transesterification and acetylation using vinyl acetate or isopropenyl acetate and lipases from Pseudomonas cepacia, Candida cylindracea, Candida rugosa, Mucor miehei or porcine pancreas lipase
05/16/2006US7045334 Nucleotide sequence encoding a benzaldehyde lyase, and process for stereoselectively synthesizing 2-hydroxyketones
05/11/2006US20060099696 Converting (R)- or (S)-cyanohydrins by enzymatic hydrolysis in presence of Rhodococcus erythropolis NCIMB 11540 into conjugate of alpha -hydroxycarboxylic acids; enantiomeric purity; carboxylation
05/10/2006EP1654371A2 Methods for the manufacture of pure single enantiomer compounds and for selecting enantioselective enzymes
05/10/2006EP1283898B1 Process for the preparation of enantiomerically enriched esters and alcohols
05/10/2006CN1771323A L-carnitin dehydrogenases, their derivatives and method for producing substituted (s) alkanols
05/04/2006WO2006046455A1 Novel carbonyl reductase, gene therefor and use thereof
05/04/2006DE10032254B4 Nukleotidsequenz kodierend für eine Benzaldehyd-Lyase und Verfahren zur stereoselektiven Synthese von (R)-2-Hydroxyketonen Nucleotide sequence encoding a benzaldehyde lyase and methods for the stereoselective synthesis of (R) -2-hydroxy ketones
05/03/2006CN1768149A Process for producing enantiopure beta-amino acid derivatives, and enantiopure beta-amino acid derivatives
05/03/2006CN1768141A Pantolactone hydrolase
05/03/2006CN1768134A Coupled cofactor-dependent enzymatic reaction system
05/03/2006CN1768030A Process for producing amino acid derivatives
04/2006
04/27/2006WO2005123932A3 Process for the preparation of optically active alpha-substituted carboxylic acids or alpha-substituted carboxylic acid amides from enantiomeric mixtures of alpha-substituted carboxylic acid amides employing pseudomonas fluorescens
04/26/2006EP1650187A1 Optically active 2-allylcarboxylic acid derivative and process for producing the same
04/25/2006US7034165 Protected 3,-5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production
04/25/2006US7033808 Carbonyl reductase, gene thereof and method of using the same
04/20/2006WO2006041062A1 Method for producing (4e)-5-chloro-2-isopropyl-4-pentenoate and optically active substance thereof
04/20/2006CA2582840A1 Processes for producing (4e)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof
04/19/2006EP1646718A2 Methods for the stereoselective synthesis and enantiomeric enrichment of b-amino acids
04/19/2006CN1761742A Process for producing lactonase and utilization thereof
04/19/2006CN1252277C Stereo selective microbe reduction of dltetralinone
04/13/2006WO2006038698A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE (S)- OR (R)-β-AMINO ACIDS AND OPTICALLY ACTIVE (R)- OR (S)-β-AMINO ACID ESTERS, 2-ALKOXYETHYL ESTERS OF β-AMINO ACIDS, AND OPTICALLY ACITVE (S)- OR (R)-2-ALKOXYETHYL ESTERS OF β-AMINO ACIDS
04/13/2006WO2006037334A1 Hydrolysis of ester bonds with lipase
04/13/2006WO2005100569A3 Methods for the preparation of optically active epoxides and vicinal diols from styrene epoxides using enantioselective epoxide hydrolases derived from yeasts
04/13/2006CA2583322A1 Processes for preparing optically active (s or r)-b-amino acid and optically active (r or s)-b-amino acid ester, and b-amino acid 2-alkoxyethyl ester and optically active (s or r)-b-amino acid 2-alkoxyethyl ester
04/12/2006CN1759185A Stereoselective chemoenzymatic process for preparing optically enriched phenylglycidates
04/11/2006US7026144 Process for preparing (-) menthol and similar compounds
04/11/2006US7026143 Enzymatic resolution of aryl and thio-substituted acids
04/06/2006WO2004076385A3 METHOD FOR PRODUCING CHIRAL α HYDROXYCARBOXYLIC CRYSTALLINE ACIDS
03/2006
03/30/2006WO2006032776A1 Method for partial or total inversion of an amine configuration
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