Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
10/2007
10/18/2007CA2648557A1 A group of novel enantioselective microbial nitrile hydratases with broad substrate specificity
10/17/2007EP1844777A1 Chronic, bolus administration of d-treo methylphenidate
10/17/2007CN101056984A Method for the production of optically-active alcohols
10/16/2007US7282605 N-allylcarboxamide derivative undergoes rearrangement reaction diastereoselectively in the presence of a base to give a 2-allylcarboxamide derivative, derivative is subjected to a carbamation reaction and solvolysis to give an optically active 2-allylcarboxylic acid ester, and ester is hydrolyzed
10/11/2007WO2007114199A1 Process for producing optically active (s)-7-hydroxy-6-methylheptane-2-one and precursor thereof
10/11/2007US20070238887 Chemo-enzymatic process for the preparation of escitalopram
10/10/2007EP1842907A1 A group of novel enantioselective microbial nitrile hydratases with broad substrate specificity
10/04/2007WO2007112299A2 Enzymatic preparation of (s) amino acid from (r,s) amino acid or from keto acid
10/04/2007WO2004101513A3 Preparation of (e)- and (z)-2-methyl-2-butenoic acids
10/03/2007EP1840218A1 Process for production of optically active (s)- or (r)- beta-amino acids and optically active (r)- or (s)-beta -amino acid esters, 2-alkoxyethyl esters of -amino acids, and optically acitve (s)- or (r)-2-alkoxyethyl esters of -amino acids
10/02/2007US7276360 Thermostable omega-transaminases
09/2007
09/26/2007EP1835927A1 Modified beta thymosin peptides
09/26/2007CN100339389C 丙型肝炎三肽抑制剂 Tripeptide inhibitor of hepatitis C
09/20/2007US20070219389 Process for Production of Cyclopentenenitrile Derivatives
09/19/2007CN101040053A Process for production of optically active (S)- or (R)- beta-amino acids and optically active (R)- or (S)-beta -amino acid esters, 2-alkoxyethyl esters of -amino acids, and optically acitve (S)- or (R
09/19/2007CN100338006C Purification of alpha-, bera- or gamma-substituted carboxylic acids
09/13/2007US20070213559 desalting step of removing a salt contained in the aqueous solution and/or formed in the neutralization step, and a step of separately collecting the optically active amino acid amide/amino acid separately from the desalted aqueous solution by a process which takes advantage of a difference in solubility
09/12/2007EP1831150A1 Process for the preparation of (2r, 3r)-2-hydroxy-3-amino-3-aryl-propionamide and (2r, 3r)-2-hydroxy-3-amino-3-aryl-propionic acid alkyl ester
09/12/2007CN101035894A Hydrolysis of ester bonds with lipase
09/12/2007CN101035753A Processes for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof
09/11/2007US7267969 Thermostable omega-transaminases
09/07/2007WO2007099107A1 Process for the preparation of optically active 5-substituted 2-oxazolidinones from racemic epoxides and cyanate employing a halohydrin dehalogenase
09/05/2007EP1829974A1 Method for producing (S)-2-butanol and 2-butanone from racemic 2-butanol employing an alcohol dehydrogenase
09/05/2007EP1828394A2 Chemical process
09/05/2007CN101031531A Proess for producing an optically active 2-methyl-alkane-1-ols from the corresponding 2-methylalk-2-en-1-als, comprising a step of enantioselective acylation to enrich one enantiomer
09/04/2007US7264960 Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates
09/04/2007US7264952 Thermostable omega-transaminases
08/2007
08/30/2007WO2007097429A1 Novel acylamidase gene and use thereof
08/29/2007EP1485471B1 Alcohol dehydrogenases with high solvent and temperature stability
08/29/2007EP0954571B1 Biocatalysts with amine acylase activity
08/29/2007CN101027404A Enantioselective biotransformation for preparation of protein tyrosine kinase inhibitor intermediates
08/29/2007CN101027277A Process for the preparation of (2R, 3R)-2-hydroxy-3-amino-3-aryl-propionamide and (2R, 3R)-2-hydroxy-3-amino-3-aryl-propionic acid alkylester
08/29/2007CN100334222C Enzyme method for preparing laevo-rotation and dextro-rotation tryptophane 15N by resolving racemic tryptophase 15N
08/29/2007CN100334198C Serration and its use in preparation of chiral precurser for dielzepin
08/23/2007WO2007094178A1 Novel (s,s)-butanediol dehydrogenase, gene for the same, and use of the same
08/23/2007US20070196905 Stereoselective bioconversion of aliphatic dinitriles into cyano carboxylic acids
08/23/2007US20070196904 Method for the production of chiral secondary alcohols
08/22/2007EP1819825A2 Thermostable omega-transaminases
08/16/2007WO2007091110A1 Enzymatic resolution process for the preparation of cycli-c beta-amino acid and ester enatiomers
08/16/2007WO2007090767A1 Biocatalytic racemisation of alpha-hydroxyketones
08/16/2007WO2007071599A3 A process for the production of an optically enriched tertiary alcohol
08/15/2007EP1817424A1 Enzyme reactions in miniemulsions
08/15/2007CN101016526A Oxidization microbacterium and method of preparing optical pure chiral aryl secondary alcohol by the same
08/08/2007EP1815002A1 Method for the production of optically-active alcohols
08/02/2007WO2007073845A3 Polypeptide having esterase activity and recombinant esterase and use thereof
08/01/2007EP1813679A1 Method for preparing optically active compound
08/01/2007EP1812581A2 Process for the preparation of an optically acitive n-carbamate protected beta-lactam by optical resolution employing a candida antarctica lipase
08/01/2007EP1032389B1 CHRONIC, BOLUS ADMINISTRATION OF D-threo METHYLPHENIDATE
08/01/2007CN1329520C Process for producing (3R,5S)-(E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin- 3-yl]-3, 5-dihydroxyhept-6-enic acid esters
08/01/2007CN101008020A Optically active cyclopropanecarboxamide preparation method
07/2007
07/26/2007WO2007084545A1 Process for making amino acids
07/26/2007WO2007083776A1 Method for production of optically active biphenylalanine compound or salt or ester thereof
07/26/2007US20070172933 Thermally stable amidases
07/25/2007EP1811037A1 Process for the preparation of optically active cyclopentenones
07/25/2007EP1811021A1 Novel carbonyl reductase, gene therefor and use thereof
07/25/2007CN101003822A Method for producing D amino acid by immobilizing acylation enzyme of penicillin
07/24/2007US7247468 Method for producing optically active 1,2-diols by microorganism culturing
07/24/2007US7247465 Screening process for hydantoin racemases
07/24/2007US7247460 Thermostable omega-transaminases
07/19/2007US20070166814 using the lipase from Candida antarctica to contact ester to form an acid intermediate; hydrolyzing
07/19/2007US20070166811 Deracemisation of Amines
07/18/2007EP1808492A1 Synthesis of intermediates for the preparation of pramipexol
07/18/2007CN1327002C Enzyme preparing method for Beta-amino acid of enriched antipode
07/12/2007WO2007077120A1 Method for producing (r) - and (s)-4-(1-ammoniumethyl)benzoic acid methylester-sulphate from racemic 4-(1-aminoethyl)benzoic acid methylester by lipase catalysed enantoselective acylation and subsequent precipitation with sulphuric acid
07/12/2007DE102006001160A1 Verfahren zur Herstellung von (R) und (S)-4-(1-Aminoethyl)benzoesäure-methylester A process for the preparation of (R) and (S) -4- (1-aminoethyl) benzoic acid methyl ester
07/11/2007EP1805316A2 Method for producing the enantiomer forms of cis-configured 3-hydroxycyclohexane carboxylic acid derivatives using hydrolases
07/11/2007EP1805314A2 Method for enantioselectively opening 3-substituted oxetan-2-ones under the action of lipases of candida antarctica or burkholderia plantarrii
07/11/2007EP1805302A1 Hydrolysis of ester bonds with lipase
07/10/2007US7241602 Nucleic acid sequences encoding enantioselective amidases
07/05/2007WO2007073875A1 Method for the enantioselective enzymatic reduction of hydroxyketo compounds
07/05/2007WO2007073846A1 Method for preparing enantiomerically enriched 2-alkyl-5-halopent-4-enecarboxylic acids and -carboxylic esters
07/05/2007WO2007073845A2 Polypeptide having esterase activity and recombinant esterase and use thereof
07/05/2007DE102005062966A1 Verfahren zur Herstellung von (R)- und (S)-4-(Ammoniumethyl)benzoesäuremethylester-sulfat A process for the preparation of (R) - and (S) -4- (ammoniumethyl) benzoate sulfate
07/05/2007CA2635380A1 Polypeptide having esterase activity and recombinant esterase and use thereof
07/05/2007CA2633583A1 Method for the enantioselective enzymatic reduction of hydroxyketo compounds
07/04/2007CN1993476A Process for the production of (s)-5-chloro-2-isopropylpent-4-enoic acid esters
07/04/2007CN1993472A Method for enantioselectively opening 3-substituted oxetan-2-ones under the action of lipases of candida antarctica or burkholderia plantarrii
06/2007
06/28/2007WO2007072753A1 Process for production of optically active 3-(3-hydroxyphenyl)-2-alkoxypropanoic acid or ester thereof
06/28/2007WO2007072159A1 Preparation of gamma-amino acids having affinity for the alpha-2-delta protein
06/28/2007US20070148742 Racemization and deprotection of special N-protected amino acids in the acylase/racemase system for the total conversion of special N-protected racemic amino acids into optically pure amino acids
06/28/2007CA2633358A1 Preparation of gamma-amino acids having affinity for the alpha-2-delta protein
06/27/2007EP1801228A1 Process for production of enantiomer-enriched compounds
06/27/2007EP1801094A1 Method for producing (4e)-5-chloro-2-isopropyl-4-pentenoate and optically active substance thereof
06/27/2007CN1989253A Method for the preparation of enantiomer forms of cis-configured 3-hydroxycyclohexane carboxylic acid derivatives using hydrolases
06/27/2007CN1323057C Process for the preparation of (1S,4R) or (1R,4S)-1-amino-4-(methylol)-2-cyclopentene and its derivatives or its salts
06/26/2007US7235399 Stereoselectively resolving a racemic mixture of 3-chloro-2-methyl-1,2-propanediol enantiomorphs by allowing at least one kind of microorganism (especially Pseudomonas) to act on it; process is enhanced by conducting it under aerobic conditions
06/21/2007WO2006063336A3 Thermostable omega-transaminases
06/21/2007CA2604928A1 Methods for obtaining optically active epoxides and diols from 2,3-disubstituted and 2,3-trisubstituted epoxides
06/20/2007EP1604030B1 Enzymatic process for stereo-selective preparation of chemical compounds in hydrofluorocarbon solvents
06/20/2007EP1409688B1 Nucleic acid sequences encoding enantioselective amidases
06/20/2007CN1322129C Novel carbonyl reductase, gene encoding it and process for producing optically active alcohols using the same
06/14/2007WO2003012126A3 Epoxide hydrolases, nucleic acids encoding them and methods for making and using them
06/14/2007US20070134775 Process for producing lactonase and utilization thereof
06/13/2007EP1309674B1 Stereoselective esterase from aspergillus oryzae
06/12/2007US7229981 Process for the preparation of aminoalcohol derivatives and their further conversion to (1R,4S)-4-(2-amino-6-chloro-5-formamido-4-pyrimidinyl)-amino)-2-cyclopentenyl-1-methanol
06/12/2007US7229817 Recombinant porcine liver esterases, their use and a method for the production thereof
06/07/2007US20070128705 Enzymatic process for stereo-selective preparation of chemical compounds in hydrofluorocarbon solvents
06/07/2007US20070128689 Reca-negative and rhab-negative microorganism
06/06/2007EP1791965A1 Enantioselective biotransformation for preparation of protein tyrosine kinase inhibitor intermediates
05/2007
05/31/2007US20070123545 (1R,4S) or (1S,4R)-1-Amino-4-(hydroxymethyl)-2-cyclopentene D- or L-hydrogen tartrate intermediates
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