Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
04/2008
04/24/2008WO2008047819A1 Novel ester hydrolase, gene encoding the same, and use thereof
04/24/2008WO2008046328A1 A levorotatory lactonohydrolase producing strain and its use for producing chiral oxyacid
04/22/2008US7361490 Amplification, translation, transcription
04/22/2008CA2261628C Process for preparing 3-pyrroline-2-carboxylic acid derivatives
04/15/2008US7358396 can be resolved using optically active carboxylic acids or enzymes; compounds such as 1-benzyloxy-3-aminobutane
04/15/2008US7358382 Two alcohol groups of 2,2-dimethyl-pentane-nitrile compound are protected with benzyl, 4-methoxybenzyl, 3,4-dimethoxybenzyl, triethylsilyl, trimethylsilyl, triisopropyl, tetrahydropyran, methyloxymethyl, allyl, trityl
04/15/2008US7358073 Process for the preparation of aminoalcohol derivatives and their further conversion to (1R, 4S)-4(2-amino-6-chloro-5-formamido-4- pyrimidinyl)-amino-2-cyclopentenyl-1-methanol
04/15/2008CA2337452C Process for the preparation of 4,5-diamino shikimic acid derivatives
04/10/2008WO2008042389A1 Specific hydrolysis of the n-unprotected (r) -ester of (3 ) -amin0-3-arylpr0pi0nic acid esters
04/10/2008WO2008041385A1 Novel alkane polyol dehydrogenase
04/09/2008EP1907556A1 Oxidoreductases for the stereoselective reduction of keto compounds
04/09/2008CN101157950A Method for preparing optical pure selenium - methyl selenium substituted aminothiopropionic acid by employing enzymatic resolution of racemic selenium- methyl selenium substituted aminothiopropionic a
04/09/2008CN100379867C Butinol I esterase
04/03/2008WO2008038050A2 Reduction of alpha-halo ketones
04/02/2008CN101153301A Method for splitting and producing L-tyrosine-**N by enzymatic method
04/02/2008CN101153300A Method for splitting and producing D-tyrosine-**N by enzymatic method
04/01/2008US7351567 Enzymatic resolution of selective estrogen receptor modulators
03/2008
03/27/2008WO2008035735A1 Method for producing optically active succinimide compound
03/26/2008EP1730274A4 Novel modified s-hydroxynitrile lyase
03/20/2008WO2008031852A1 Method for producing optically active 2-benzyloxycyclohexylamine
03/20/2008DE102006039189A1 Enantioselektive Darstellung von aliphatischen azyklischen Estern und Ketonen Enantioselective preparation of aliphatic acyclic esters and ketones
03/19/2008EP1613745B1 L-carnitin dehydrogenases, their derivatives and method for producing substituted (s) alkanols
03/19/2008CN101143892A 丙型肝炎三肽抑制剂 Tripeptide inhibitor of hepatitis C
03/18/2008CA2151769C The preparation of enantiomerically pure lactams
03/13/2008WO2008028654A1 Process for preparation of optically active n-protected 3 -aminopyrrolidine or optically active n-protected 3-aminopiperidine and the corresponding ketones by optical resolution of the racemic amine mixtures employing a bacterial omega-transaminase
03/13/2008WO2007112299A3 Enzymatic preparation of (s) amino acid from (r,s) amino acid or from keto acid
03/13/2008CA2659300A1 Process for preparation of optically active n-protected 3-aminopyrrolidine or optically active n-protected 3-aminopiperidine and the corresponding ketones by optical resolution ofthe racemic amine mixtures employing a bacterial omega-transaminase
03/12/2008EP1897956A1 Process for preparation of optically active amines by optical resolution of racemic amines employing a bacterial omega-transaminase
03/12/2008EP1116795B1 Process for producing optically active pyridineethanol derivatives
03/11/2008US7341859 ADH from Rhodococcus erythropolis
03/11/2008CA2237297C Process for the preparation of (1s,4r)-or(1r,4s)-4-(2-amino-6-chloro-9h-purin-9-yl)-2-cyclopentene-1-methanol
03/06/2008WO2007115797A3 A group of novel enantioselective microbial nitrile hydratases with broad substrate specificity
03/05/2008CN101137614A Preparation of chiral propargylic alcohol and ester intermediates of himbacine analogs
03/05/2008CN101134943A Bacillus alcaligenes and method for preparing single enantiomer amygdalic acid
03/05/2008CN100372926C Pseudomonas putida and application thereof for mandelic acid racemate resolution
03/04/2008US7338945 (1R,4S) or (1S,4R)-1-Amino-4-(hydroxymethyl)-2-cyclopentene D- or L-hydrogen tartrate intermediates
02/2008
02/28/2008WO2008022394A1 Reaction system
02/27/2008CN101130805A Method for enzymatically splitting and preparing chiral 1-aryl-3-chlorine-1, 2-propylene glycol
02/26/2008US7335502 Protein comprising an amino acid sequence having a chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase activity; stereoselectivity ; can produce an optically active compound with an industrial scale by using microorganisms with the gene
02/20/2008EP1889903A1 Biocatalysts with amine acylase activity
02/14/2008US20080038802 Method of Making Optically Active Ester Derivatives and Their Acids From Racemic Esters
02/13/2008EP1887086A1 Process for production of carboxylic acid using surfactant-modifying enzyme
02/13/2008EP1885849A2 Methods for obtaining optically active glycidyl ethers and optically active vicinal diols from racemic substrates
02/13/2008EP1805314B1 Process for the enantioselective opening of 3-substituted oxetan-2-ones employing lipases of candida antarctica or of burkholderia plantarrii
02/12/2008US7329518 Producing polycyclic pyridineethanol derivative by causing an enzyme or enzyme source to act on polycyclic acetylpyridine derivatives
02/12/2008CA2440025C Aminoketone asymmetric reductase and nucleic acid thereof
02/12/2008CA2258701C Carboxamide derivatives of pyrrolidine, piperidine and hexahydroazepine for the treatment of thrombosis disorders
02/06/2008EP1324980B1 Citrullimycines, a process for their production and their use as pharmaceuticals
02/05/2008US7326559 Reacting an allene derivative containing two hydroxy or two ester groups in presence of esterase or lipase enzyme catalyst with an unsaturated ester when ( both are hydroxy groups) or with water when (both are ester groups); chemical intermediates for medicinal and agricultural active agents
01/2008
01/31/2008US20080025218 Method, Apparatus, Edge Router and System for Providing Qos Guarantee
01/24/2008WO2008009710A1 Process for the production of fluorine containing alpha-hydroxy carboxylic acids
01/23/2008EP1881077A1 Process for the production of fluorine containing a-hydroxy carboxylic acids
01/23/2008EP1880991A1 Method of separating and collecting optically active amino acid amide
01/23/2008EP1427721B1 Method for synthesis of 5-(3-pyridylmethylene)-imidazolidine-2,4-dione
01/16/2008EP1673327B1 Process for the preparation of alkynols
01/16/2008EP1506177B1 Process for the preparation of the enantiomeric forms of 2-substituted 2-(2,5-dioxoimidazolidin-1-yl)-acetic acid derivatives
01/15/2008US7319027 Contacting chiral primary amine, omega-transaminase, and amino acceptor to convert into ketone; stereospecific; gene expression; can be used to enrich enantiomerically a mixture of chiral amines or to synthesize stereoselectively one of a pair of chiral amines
01/15/2008CA2303195C Optically active 1,4-benzodioxine-2-carboxylic acid derivatives and process for producing the same
01/03/2008WO2008000738A1 Proteins with esterase activity
01/02/2008CN100359019C Enzymatic deprotection of amines and hydroxides
01/01/2008US7314739 Lipase variants
01/01/2008US7314738 Nucleotide sequences coding hydantoinase/hydrolases for producing pharmaceuticals, chemical industrial products and food; for producing the D-amino acid efficiently from the 5-substituted hydantoin
12/2007
12/27/2007DE102006028818A1 Verfahren zur Herstellung enantiomerenangereicherter Amine und Amide durch enzymatische Racematspaltung Process for the preparation of enantiomerically enriched amines and amides by enzymatic resolution
12/26/2007EP1870475A1 Process for the preparation of optically active amines and amides employing a hydrolase and sulfonyl acetic acid ester as the acyl donor
12/26/2007CN101092641A Process for the preparation of enantiomerically enriched amines and amides by enzymatic resolution
12/19/2007EP1867730A1 Process for production of optically active hydroxymethyl -substituted phenylalanine
12/19/2007CN100355900C Method for enzyme catalytic resolution of N substituted alpha amino acid
12/12/2007CN100354422C Ester hydrolase and its gene and recombinant enzyme
12/06/2007US20070281339 Methods For Obtaining Optically Active Epoxides and Vicinal Diols From Styrene Oxides
12/06/2007CA2653054A1 Methods and systems for increasing production of equilibrium reactions
12/05/2007EP1470220A4 Selective enzymatic esterification and solvolysis of epimeric vitamin d analog and separation of the epimers
12/05/2007CN101082058A Method of resolution and racemic mixture of nucleoside enantiomers
12/04/2007CA2257562C Enzymatic process for the preparation of (s)-cyanohydrins
11/2007
11/29/2007US20070276150 Process for the Preparation of Alkynols
11/28/2007CN101080495A Chemical process
11/28/2007CN100351389C Non-homogeneous systems for resolution of enantiomeric mixtures
11/27/2007US7300775 Genetic engineered nucleic acid promoter
11/22/2007CA2649939A1 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
11/21/2007CN101074446A Decomposition of tert-leucine with optical activity
11/21/2007CN101074228A Method for preparing medicine composition containing 1,3-oxathin cyclopentane nucleoside analogues
11/15/2007WO2007129018A1 Process for dynamic kinetic resolution (dkr) of racemic compounds in (hydro) fluorocarbon solvents
11/15/2007WO2007128469A1 Process for the preparation of enantiomerically enriched nitriles
11/15/2007WO2003000840A3 Nitrilases
11/14/2007EP1854893A1 Process for producing optically active secondary alcohol
11/07/2007EP1852510A1 5-substituted hydantoin racemase, dna encoding the same, recombinant dna, transformed cell, and process for production of optically active n-carbamylamino acid or optically active amino acid
11/07/2007EP1851311A2 Enzymatic enantioselective ester or amide hydrolysis or synthesis
11/07/2007CN101068780A Methods for the preparation of stereoisomerically enriched amines
11/07/2007CN101066970A Method for preparing medicine composition containing 1,3 oxathiolane nucleoside analogue
11/01/2007WO2007096314A3 Enzymatic resolution of racemic 3-aryl-4-aminobutyric acid
10/2007
10/31/2007EP1848683A2 Preparation of chiral propargylic alcohol and ester intermediates of himbacine analogs
10/31/2007CN101065494A Enzyme reactions in miniemulsions
10/31/2007CN101063157A Method for catalyzing and splitting 2-aryl ethylformic acid antimer by using Serratieae fat enzyme
10/31/2007CN101063156A Method for preparing (R)-6-hydroxy-8-chlorine octanoic acid ethyl by enzyme resolution
10/31/2007CN101063153A Method for improving single batch conversion bubatrate concentration in alloisomerism preparation of styrene glycol
10/25/2007WO2007118682A1 Process for the preparation of enantiomeri cally enriched beta-amino alcohols starting from glycine and an aldehyde in the presence of a threonine aldolase and a decarboxylase
10/25/2007US20070249025 Enzymatic resolution of selective estrogen receptor modulators
10/25/2007CA2648697A1 Process for the preparation of enantiomeri cally enriched beta-amino alcohols starting from glycine and an aldehyde in the presence of a threonine aldolase and a decarboxylase
10/24/2007CN101058817A Ester hydrolase with R-isomer stereoselectivity, gene and recombination enzyme thereof
10/23/2007US7285410 Using trangenic microorganism having nitrilase and amidase activities to convert (E,Z)-2-methyl-2-butenenitrile into (E and Z)-2-methyl-2-butenoic acids
10/18/2007WO2007115797A2 A group of novel enantioselective microbial nitrile hydratases with broad substrate specificity
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