| Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784) |
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| 10/09/2008 | WO2008120554A1 Novel amidase, gene for the same, vector, transformant, and method for production of optically active carboxylic acid amide and optically active carboxylic acid by using any one of those items |
| 10/09/2008 | US20080250535 Using vector transformation to express amino acid oxidase and phosphinothricin and preferential destroy or prevent gamete formation in plants |
| 10/08/2008 | EP1634957B1 2-alkylcysteinamide or salt thereof, process for producing these, and use of these |
| 10/07/2008 | US7431944 One-a-day, oral administration of a methylphenidate drug, e,g, Ritalin, the dosage of which form provides an immediate dose upon ingestion followed by release of more dose(s) later; particles uncoated/coated with ammonio methacrylate |
| 10/02/2008 | WO2008067981A3 Whole-cell catalytic system comprising a hydantoinase, a racemase and a carbamoylase |
| 10/01/2008 | EP1973867A1 Preparation of gamma-amino acids having affinity for the alpha-2-delta protein |
| 10/01/2008 | CN100422319C Method for producing chiral carboxylic acids from nitriles with assistance of nitrilase or microorganisms which contain gene for nitrilase |
| 09/30/2008 | USRE40525 Hepatitis C inhibitor tri-peptides |
| 09/24/2008 | CN101273137A Oxidoreductases for the stereoselective reduction of keto compounds |
| 09/18/2008 | US20080227132 Hydrolase Enzymes and Their Use in Kinetic Resolution |
| 09/17/2008 | EP1969129A1 Method for producing (r) - and (s)-4-(1-ammoniumethyl)benzoic acid methylester-sulphate from racemic 4-(1-aminoethyl)benzoic acid methylester by lipase catalysed enantoselective acylation and subsequent precipitation with sulphuric acid |
| 09/16/2008 | US7425530 Stereoselective preparation of cyclic L-amino acids |
| 09/11/2008 | US20080220485 Aziding epichlorohydrin in presence of halohydrin dehalogenase to form alcohol |
| 09/10/2008 | EP1966373A2 Novel polypeptide having esterase activity and recombinant esterase and use thereof |
| 09/10/2008 | CN101260415A Preparation of two kinds of high optical activity enantiomer of ethyl 4-cyano-3-hydroxybutyrate by biological catalysis method |
| 09/04/2008 | WO2008105493A1 Method for production of optically active amino acid |
| 09/04/2008 | CA2679503A1 Nitrilases, nucleic acids encoding them and methods for making and using them |
| 09/03/2008 | EP1964925A1 Process for production of optically active 4-hydroxy-1,2,3,4 -tetrahydroquinolines |
| 09/03/2008 | EP1963516A1 Method for the enantioselective enzymatic reduction of hydroxyketo compounds |
| 09/03/2008 | EP1375495B1 Method for producing a 2-azetidinone derivative |
| 09/03/2008 | CN100415892C Method for the microbiological isomerisation of alpha-hydroxy carboxylic acids |
| 09/02/2008 | CA2234412C Method for producing optically active compound |
| 09/02/2008 | CA2204743C D-pantolactone hydrolase and gene encoding the same |
| 08/28/2008 | WO2008102720A1 Method for producing optically active 3-aminopiperidine or salt thereof |
| 08/28/2008 | US20080206827 Method for producing chiral a-hydroxycarboxylic crystalline acids |
| 08/27/2008 | EP1491633B1 Novel carbonyl reductase, gene encoding it and process for producing optically active alcohols using the same |
| 08/27/2008 | EP1053258B8 Device for producing polymer support materials in the form of porous polymer beads |
| 08/27/2008 | CN101253271A Method for production of optically active alpha-hydroxycarboxylic acid |
| 08/27/2008 | CN101253262A New esterases and their use for processes for kinetic resolution of butinolesters |
| 08/27/2008 | CN101250546A Lipase gene as well as engineering bacterium and lipase strain |
| 08/27/2008 | CN101250492A Agrobacterium strain and method for preparing left-lateral lactone compounds thereby |
| 08/27/2008 | CN100413972C Enzymatic catalyzing process for the preparation of substituted 2-amino-3-(2-amino-phenylsulfanyl)-propionic acid |
| 08/27/2008 | CN100413967C (R)-2-octanol dehydrogenase, process for producing enzyme, DNA encoding enzyme and process for producing alcohol by using same |
| 08/21/2008 | WO2008099730A1 Method for production of amine compound using optically active 2-(aroyloxy)propionic acid |
| 08/21/2008 | WO2007072159B1 Preparation of gamma-amino acids having affinity for the alpha-2-delta protein |
| 08/20/2008 | EP1959019A1 Method for enzymatic reduction of alkene derivates |
| 08/20/2008 | CN101248184A Process for production of optically active (S or R)-a-amino acid or optically active (S or R)-a -amino acid ester |
| 08/20/2008 | CN100412062C Synthesis of enantiomerically pure amino-substituted fused bicyclic rings |
| 08/19/2008 | US7413883 Enantioselective immobilized lipase |
| 08/13/2008 | EP1572363A4 High capacity methods for separation, purification, concentration, immobilization and synthesis of compounds and applications based thereupon |
| 08/13/2008 | CN101240314A Enzyme catalysis alcoholysis reaction resolution method for preparing optical activity 4-Hydroxy-3-methyl-2-(2-propynyl)-2-cyclopentene-1-one |
| 08/13/2008 | CN101240257A Micro-bacilus, mutagenesis method and application thereof in chiral medicament intermediate production |
| 08/06/2008 | CN101235403A Chiral method for preparing D-ornithine and putrescine or derivatives thereof |
| 08/06/2008 | CN100408689C Process for producing D-alanine |
| 08/05/2008 | CA2142444C Enzymatic asymmetric reduction process to produce 4 h - thieno (2,3-6) thio pyrane derivatives |
| 08/05/2008 | CA2137378C D-enzyme compositions and methods of their use |
| 07/30/2008 | EP1383886B1 D-hydantoinase from ochrobactrum anthropi |
| 07/29/2008 | US7405070 Reacting with methanol and thionyl chloride using Savinase, Alcalase, Protease and Acylase; superior optical purity and yield |
| 07/29/2008 | US7405065 Such as 1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene via N-acetylamino-alcohol hydrolase isolated from Rhodococcus, Gordona, Arthrobacter, Alcaligenes, Agrobacterium/Rhizobium, Bacillus, Pseudomonas or Alcaligenes/Bordetella |
| 07/24/2008 | WO2007073845A8 Polypeptide having esterase activity and recombinant esterase and use thereof |
| 07/23/2008 | CN101225427A Method for improving reaction rate of enzymatic ibuprofen chiral separation |
| 07/23/2008 | CN100404686C Separation and isomerization method for vitamin D derivative isomer |
| 07/22/2008 | US7402695 desalting step of removing a salt contained in the aqueous solution and/or formed in the neutralization step, and a step of separately collecting the optically active amino acid amide/amino acid separately from the desalted aqueous solution by a process which takes advantage of a difference in solubility |
| 07/22/2008 | US7402383 Using site directed mutagenesis and polymerase chain reaction replication to produce polypeptides of preferential characteristics; directed protein evolution |
| 07/22/2008 | CA2343346C Process for the preparation of 4,5-diamino shikimic acid derivatives |
| 07/17/2008 | DE112006002442T5 Verfahren zur Herstellung von optisch aktivem Theaspiran A process for producing optically active Theaspiran |
| 07/17/2008 | DE112006002419T5 Verfahren zur Herstellung von optisch aktivem α-Ionen A process for producing optically active α-ion |
| 07/17/2008 | CA2666348A1 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
| 07/16/2008 | CN101220336A Saccharomycete with stereoselectivity lipase liveness and application in producing S- type betaxolol hydrochloride with biological split method thereof |
| 07/16/2008 | CN100402640C Process for producing lactonase and utilization thereof |
| 07/09/2008 | EP1942193A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE (S OR R)-a-AMINO ACID OR OPTICALLY ACTIVE (S OR R)-a -AMINO ACID ESTER |
| 07/09/2008 | EP1196590B1 Process of separation of epoxide-enantiomer mixtures by epoxide-hydrolase producing microorganisms |
| 07/09/2008 | CN101215534A Organic solvent resisting basified protease producing strain, gene and application thereof |
| 07/09/2008 | CN100400669C Stereoselective chemoenzymatic process for preparing optically enriched phenylglycidates |
| 07/02/2008 | EP1937809A1 New esterases and their use for processes for kinetic resolution of butinolesters |
| 07/02/2008 | EP1601778B1 Stereoselective chemoenzymatic process for preparing optically enriched phenylglycidates |
| 07/02/2008 | EP1173585B1 Epoxide hydrolases of aspergillus origin |
| 07/01/2008 | US7393679 Enzyme for degrading hyaluronic acid to amino acid; genetic engineered gene |
| 06/26/2008 | WO2008074506A1 Optical resolution of a mixture of enantiomers of butynol or butenol |
| 06/26/2008 | WO2008038050A3 Reduction of alpha-halo ketones |
| 06/25/2008 | EP1306438B1 Novel carbonyl reductase, gene thereof and method of using the same |
| 06/25/2008 | CN100396785C Resoldution method for racemic compound of nucleoside enantiomorph |
| 06/24/2008 | US7390647 Converting (R)- or (S)-cyanohydrins by enzymatic hydrolysis in presence of Rhodococcus erythropolis NCIMB 11540 into conjugate of alpha -hydroxycarboxylic acids; enantiomeric purity; carboxylation |
| 06/19/2008 | WO2008072764A1 Method for producing optically active (r)- or (s)-piperidine-3-carboxylic acid compound and (s)- or (r)-piperidine-3-carboxylic acid alkyl ester compound |
| 06/19/2008 | WO2008071695A1 R-hnl random variants and their use for preparing optically pure, sterically hindered cyanohydrins |
| 06/18/2008 | EP1835927A4 Modified beta thymosin peptides |
| 06/11/2008 | EP1930441A1 Method for production of optically active -hydroxycarboxylic acid |
| 06/11/2008 | CN101198704A Enzymatic transformation of a prostaglandin (bimatoprost) intermediate |
| 06/10/2008 | CA2129046C Opioid diarylmethylpiperazines and piperidines |
| 06/05/2008 | WO2008022627A3 Method for the production of optically active hydroxyalkyl acetates by racemate resolution of 4-hydroxy-2 ketones with the help of baeyer-villger monooxygenases |
| 06/04/2008 | CN100392090C Enzyme method for detaching and preparing L-methionine-15N and D-methionine-15N |
| 05/29/2008 | US20080124784 Novel Modified S-Hydroxynitrile Lyase |
| 05/28/2008 | EP0938584B1 Method of preparing (s) - or (r) -3,3,3-trifluoro-2-hydroxy-2- methylpropionic acid |
| 05/28/2008 | CN101186944A Biological resolution method for amino acid |
| 05/28/2008 | CN101186937A Non-homogeneous systems for the resolution of enantiomeric mixtures |
| 05/27/2008 | US7378269 Racemization and deprotection of special N-protected amino acids in the acylase/racemase system for the total conversion of special N-protected racemic amino acids into optically pure amino acids |
| 05/22/2008 | WO2008058951A1 Process for enzymatic reduction of alkene derivatives |
| 05/21/2008 | EP1428876B1 Novel amide hydrolase gene |
| 05/20/2008 | US7374926 Enantioconvergent chemoenzymatic synthesis of (R)-γ-amino-β-hydroxybutyric acid ((R)-GABOB) |
| 05/15/2008 | US20080115247 Chemical Process |
| 05/14/2008 | EP1733042B1 Chemo-enzymatic process for preparing escitalopram |
| 05/14/2008 | CN101180402A Process for production of carboxylic acid using surfactant-modifying enzyme |
| 05/14/2008 | CN101177678A Magnetic nano particle enzyme immobilization as well as preparation method and uses thereof |
| 05/13/2008 | US7371901 Process for the preparation of alkynols |
| 05/13/2008 | US7371555 Polypeptides having α-H-α-amino acid amide racemase activity and nucleic acids encoding the same |
| 05/07/2008 | EP1020458B1 Optically active 1,4-benzodioxine-2-carboxylic acid derivatives and process for producing the same |
| 05/02/2008 | WO2008051563A1 Mandelic acid derivatives and preparation thereof |
| 05/02/2008 | CA2667287A1 Mandelic acid derivatives and preparation thereof |
| 04/30/2008 | EP1819825A4 Thermostable omega-transaminases |
| 04/30/2008 | CN100385007C Process for preparing (R)-mandelic acid by microbial asymmetric resolution |