Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
05/2009
05/13/2009CN101432435A Method for the enantioselective enzymatic reduction of hydroxyketo compounds
05/12/2009US7531331 Butynol I esterase
05/12/2009US7531330 Heat resistant lyase for use in producing optically active cyanohydrins; drug design
05/06/2009EP2054510A2 Enantioselective representation of aliphatic acyclic esters and ketones
05/06/2009EP2003211A9 Process for producing optically active (s)-7-hydroxy-6-methylheptane-2-one and precursor thereof
05/06/2009CN101423861A Biocatalysis preparation method of L-aminoacid derivates
04/2009
04/29/2009EP1105413B1 Hepatitis c inhibitor tri-peptides
04/29/2009CN101418291A Method for preparing S type cyclopentenone by sol-gel embedding immobilized enzyme
04/29/2009CN100482800C Steroselective preparation of cyclic L-amino acids
04/29/2009CN100482792C Hydantoin racemase
04/29/2009CN100482641C Protected 3,5-dihydroxy-2, 2-dimethyl-valeronitriles for synthesis of epothilones and derivatives and method for preparaton and use thereof
04/23/2009WO2009050216A1 Process for the preparation of an enantiomerically and/or diastereomerically enriched ester, thioester, alcohol or thiol
04/21/2009US7521216 Nitrilases and methods for making and using them
04/15/2009EP2046967A1 Process for the production of fluorine containing alpha-hydroxy carboxylic acids
04/15/2009EP1805316B1 Process for the preparation of the enantiomeric forms of cis-3-hydroxycyclohexane carboxylic acid derivatives employing hydrolases
04/15/2009EP1573018B1 Chemoenzymatic process for stereoselective preparation of r- and s-enantiomers of 2-hydroxy-3-(2-thienyl) propanenitrile
04/09/2009CA2701114A1 Production of monatin stereoisomers
04/08/2009EP1815002B1 Process for the preparation of (s)-butan-2-ol
04/07/2009US7514245 Method for producing chiral α-hydroxycarboxylic acids by enzymatic hydrolysis of chiral cyanohydrins
04/02/2009WO2009042984A1 Ketoreductase polypeptides and uses thereof
04/02/2009WO2009009117A3 Chemoenzymatic processes for preparation of levetiracetam
04/02/2009WO2009007460A3 Enantioselective reduction
04/02/2009US20090088455 Chronic, Bolus Adminstration Of D-Threo Methylphenidate
04/02/2009US20090087885 Process For Preparing Optically Active Amino Acids Using a Whole-Cell Catalyst
03/2009
03/26/2009DE102007044379A1 Procedure for the conversion of substrates e.g. organic sulfides, ketones and amino acids, to products by a combined electrochemical and catalytic process in a reaction medium containing ionic liquid`
03/25/2009EP2039762A2 Nitralases
03/25/2009EP2038407A1 Proteins with esterase activity
03/25/2009CN100471950C Polypeptides having alpha- h-alpha-amino acid amide racemase activity and nucleic acids encoding the same
03/19/2009WO2009035407A1 Use of intermediates ((r ) -2,2, 4-trimethyl-l, 3-dioxolane-4-yl) methanol (a), 3-f luoro-4-nitro-phenol (b) and 1- (4-chloro- benzyl) -piperidin-4-ylamine (c)
03/19/2009US20090075329 Chemically modified mutant serine hydrolases show improved catalytic activity and chiral selectivity
03/12/2009DE102007042600A1 Verfahren zur Herstellung von enantiomerenangereichten Aminen A process for preparing amines enantiomerenangereichten
03/11/2009EP2033654A1 Macrocyclic isoquinoline peptide inhibitors of hepatitis c virus
03/11/2009EP1969129B1 Process for the preparation of (r)- and (s)-4-(1-aminomethyl) benzoic acid methylester-sulphate from racemic 4-(1-aminoethyl)benzoic acid methylester
03/04/2009CN101379193A Biocatalytic racemisation of alpha-hydroxyketones
03/04/2009CN100465286C A preparation method of optically active propoxyaniline derivatives
02/2009
02/25/2009EP2028186A2 Hepatitis C inhibitor tri-peptides
02/24/2009CA2468370C Chronic, bolus administration of d-threo methylphenidate
02/18/2009EP1634958B1 Method for producing optically active chroman-carboxylate
02/18/2009EP1629000B1 Macrocyclic isoquinoline peptide inhibitors of hepatitis c virus
02/18/2009CN101370943A Production method of optically active biphenyl alanine compound or salt thereof and ester thereof
02/18/2009CN101368199A Method for preparing D-aminophenol with immobilization penicillin acylated enzyme catalysis
02/17/2009US7491494 Evolving new molecular function
02/11/2009EP1444367B1 Reca-negative and rhab-negative microorganism
02/11/2009CN101363015A Epoxide hydrolases from streptomyces
02/05/2009US20090035815 Synthetic Gene for Enhanced Expression in E. Coli
02/03/2009US7485452 Method of making optically active ester derivatives and their acids from racemic esters
01/2009
01/28/2009EP1812581B1 Process for the preparation of optically active n-carbamate protected beta-lactams by optical resolution employing a candida antarctica lipase
01/28/2009EP1739914B1 Method, apparatus, edge router and system for providing a guarantee of the quality of service (qos)
01/27/2009CA2170059C Resolution of the racemates of primary and secondary amines by enzyme-catalyzed acylation
01/21/2009EP2017259A2 Preparation of gamma-amino acids having affinity for the alpha-2-delta protein
01/21/2009CN101351548A Novel polypeptide having esterase activity and recombinant esterase and use thereof
01/15/2009WO2009008834A1 Microbial kinetic resolution of ethyl-3,4-epoxybutyrate
01/15/2009WO2009007759A1 Resolution process
01/15/2009WO2009007460A2 Enantioselective reduction
01/15/2009US20090017510 Enzymic method for the enantioselective reduction of keto compounds
01/14/2009EP1573019B1 Stereoselective process for the production of dioxolane nucleoside analogues
01/07/2009EP2011794A2 Process for the preparation of 5-(3-pyridylmethylene)-imidazolidine-2,4-dione
01/07/2009EP2010666A1 Process for dynamic kinetic resolution (dkr) of racemic compounds in (hydro) fluorocarbon solvents
01/07/2009CN101341117A Preparation of gamma-amino acids having affinity for the alpha-2-delta protein
01/07/2009CN101338287A Bacillus subtilis esterase and application thereof for producing 1-menthol
12/2008
12/31/2008CN101333554A Method for producing D-lactic acid by enzyme resolution of D,L-lactic Acid
12/30/2008US7470526 from 4-(4-dimethylamino)-1-(4'-fluorophenyl)-1-(hydroxybutyl)-3-(acyloxymethyl)benzonitrile by means of enzymatic enantiomeric resolution
12/24/2008EP2004838A1 Process for the preparation of steroid derivatives by reduction of oxosteroid compounds or by oxidation of hydroxysteroid compounds using a hydroxysteroid dehydrogenase
12/24/2008EP2004836A1 Process for the preparation of enantiomeri cally enriched beta-amino alcohols starting from glycine and an aldehyde in the presence of a threonine aldolase and a decarboxylase
12/24/2008EP2004814A2 A group of novel enantioselective microbial nitrile hydratases with broad substrate specificity
12/17/2008EP2003211A2 Process for producing optically active (s)-7-hydroxy-6-methylheptane-2-one and precursor thereof
12/17/2008EP1222305B1 Enzymatic process for the resolution of enantiomeric mixtures of beta-lactams
12/16/2008US7465842 Enantioselective biotransformation for preparation of protein tyrosine kinase inhibitor intermediates
12/11/2008US20080305534 Novel Glycerol Dehydrogenase, Gene Therefor, and Method of Utilizing the Same
12/10/2008CN101321875A Method for producing (R) - and (S)-4-(1-ammoniumethyl)benzoic acid methylester-sulphate from racemic 4-(1-aminoethyl)benzoic acid methylester by lipase catalysed enantoselective acylation and subseque
12/09/2008CA2202652C Production of peptides in plants as viral coat protein fusions
12/09/2008CA2172954C Enzyme and its use in preparing (s)-pipecolic acid
12/04/2008US20080299623 Enzyme catalysis in the presence of ionic liquids
12/03/2008CN101314787A Method for preparing optical activity chirality secondary alcohol with rhodotorula reductase formulation
12/02/2008US7459301 Stereoisomerically enriched N-protected β-lactams using candida antarctica
11/2008
11/26/2008EP1994162A1 Process for the preparation of optically active 5-substituted 2-oxazolidinones from racemic epoxides and cyanate employing a halohydrin dehalogenase
11/20/2008WO2008140127A1 Process for producing optically active 2-alkyl-1,1,3-trialkoxycarbonylpropane
11/20/2008US20080286832 Methods for Obtaining Optically Active Epoxides and Vicinal Diols From 2,2-Disubstituted Epoxides
11/19/2008EP1992609A1 A process for the preparation of a (S)(+)-3-(aminomethyl)-5-methylhexanoic acid
11/18/2008US7452703 Uranium enrichment using microorganisms
11/14/2008CA2631110A1 A process for the preparation of (s)(+)-3-(aminomethyl)-5-methylhexanoic acid
11/12/2008EP1440155B1 Lipase variants
11/12/2008CN101302543A Method for preparing (S)-benzoglycol by microorganism unsymmetrical split
11/12/2008CN101302503A Mutated plant lactobacillus plantarum D-lactate dehydrogenases, genes, recombinase and use thereof
11/11/2008US7449325 Process for enzymatically producing either optically active N-substituted β-amino acids or esters thereof or optically active N-substituted 2-homopipecolic acids or esters thereof
10/2008
10/30/2008WO2008129873A1 Phenylalanine aminomutase with selectivity for s-form, dna encoding the same, method for producing (s)-β-phenylalanine and method for producing (s)-β-phenylalanine analogs
10/29/2008EP1985700A1 Novel (s,s)-butanediol dehydrogenase, gene for the same, and use of the same
10/29/2008EP1984515A1 Biocatalytic racemisation of alpha-hydroxyketones
10/28/2008CA2252616C Biocatalysts with amine acylase activity
10/28/2008CA2221800C Reduction of ketone groups
10/22/2008EP1982985A2 Method for manufacturing a purine derivative
10/22/2008EP1045025B1 (S)-alpha-PHENETHYLAMINE : PYRUVATE TRANSAMINASE
10/22/2008CN100427608C Process for resolution preparation of allyl furfural alcohol with optical activity by enzyme method
10/21/2008US7439036 Process for producing optically active octahydro-1H-indole-2-carboxylic acid
10/15/2008EP1980622A1 Method for production of optically active biphenylalanine compound or salt or ester thereof
10/15/2008CN101285059A Immobilization process of microbacterium sp and process for preparing gamma-lactam
10/15/2008CN101284769A Synthetic method for mainly intermediate compounds of anti-hypertensive drug aliskiren
10/14/2008US7435574 Whole cell catalyst which expresses lactobacillus oxidase for use in generating/producing chrial enantiomer-enriched organic compounds
10/14/2008CA2340218C Process for producing optically active tropinonemonocarboxylic acid ester derivative
10/09/2008WO2008120567A1 Method for collection of l-biphenylalanine compound salt, and method for collection of biphenylalanine ester compound using the same
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