Patents
Sitemap › C12 - Biochemistry; Beer; Spirits; Wine; Vinegar; Microbiology; Enzymology; Mutation or genetic engineering › C12P - Fermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture › C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture
Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
12/2009
12/23/2009CN101611141A R-HNL random variants and their use for preparing optically pure, sterically hindered cyanohydrins
12/23/2009CN100572348C Process for preparing the enantiomeric forms of cis-configured 1,3-cyclohexanediol derivatives
12/22/2009CA2407559C Process for the preparation of pharmaceutically acceptable salts of (ss-rs)-s-adenosyl-l-methionine
12/22/2009CA2114221C 1, 3-oxathiolane nucleoside analogues
12/16/2009CN100569950C Fermentative production of D-p-hydroxyphenylglycine and D-phenylglycine
12/16/2009CN100569736C Process for producing amino acid derivatives
12/15/2009US7632948 reacting 8-amino-1,2,3,4-tetrahydro-isoquinoline with chloral hydrate and hydroxylamine hydrochloride to give an N-(1,2,3,4-tetrahydro-isoquinolin-8-yl)-2-hydroxyimino-acetamide, adding H2SO4 to provide a 2,3-dioxo-2,3,6,7,8,9-hexahydro-1H-pyrrolo[3,2-h]isoquinoline, finally reacting with butyrolactone
12/15/2009CA2481078C Method and compositions for the synthesis of bch-189 and related compounds
12/10/2009WO2008058951A8 Process for enzymatic reduction of alkene derivatives
12/09/2009EP2130925A1 Method for production of optically active amino acid
12/09/2009CN100567321C Oxidoreductase from pichia capsulata
12/02/2009EP2128258A1 Novel amidase, gene for the same, vector, transformant, and method for production of optically active carboxylic acid amide and optically active carboxylic acid by using any one of those items
12/02/2009CN101591693A Method for preparing D-cysteine by using enzyme conversion
12/02/2009CN101591664A High-enantiomer selectivity epoxide hydrolase and gene coded thereby
12/02/2009CN100564536C Method for splitting and producing L-tyrosine-**N by enzymatic method
11/2009
11/26/2009CA2724828A1 Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester
11/25/2009EP2123769A1 Method for producing optically active 3-aminopiperidine or salt thereof
11/25/2009EP2123760A1 Enzymatic method for enantioselective reduction of keto compounds
11/25/2009CN101589152A Process for the production of fluorine containing alpha-hydroxy carboxylic acids
11/24/2009CA2445046C Nitrilases
11/18/2009EP2119770A1 Production of alpha-oxyfunctionalized carbonyl compounds
11/18/2009CN101580864A Method for producing optically pure L-alanine by one pseudomonas and two enzymes
11/18/2009CN101580863A Application of poultry livers in preparing chiral antimer by splitting racemation epoxy chloropropane
11/18/2009CN101580862A Device and method for preparing diltiazem chiral precursor by using immobilized lipase
11/12/2009US20090280558 Process For Dynamic Kinetic Resolution (DKR) Of Racemic Compounds In (Hydro) Fluorocarbon Solvents
11/11/2009EP2115153A2 Nitrilases, nucleic acids encoding them and methods for making and using them
11/11/2009CN100558905C Method for preparing (R)-6-hydroxy-8-chlorine octanoic acid ethyl by enzyme resolution
11/11/2009CN100558901C A method of selectively producing male or female sterile plants
11/05/2009US20090275077 Methods of Obtaining Optically Active Epoxides and Vicinal Diols from Styrene Oxides
11/04/2009EP2113031A1 Optically active, heteroaromatic beta-hydroxy esters, processes for their preparation from beta-keto esters and processes for the preparation of these beta-keto esters
11/03/2009US7611886 selective enzymatic acetylation of (1S,5R,6R,7R)-6-[(3S)-3-hydroxy-5-phenyl-1-pentenyl]-7-[(4-benzoyl)oxy]-2-oxabicyclo[3,3,0]octan-3-one; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-5-N-ethylheptenamide
10/2009
10/28/2009CN101565685A Gene recombination bacterium and application thereof in preparing chiral pure acetoin and 2,3-butanediol
10/28/2009CN100554403C Oxidized microbacterium and method of preparing optical pure chiral aryl secondary alcohol by the same
10/21/2009CN101563160A Reaction system
10/14/2009EP1313860B1 Butinol i esterase
10/14/2009CN101558159A Specific hydrolysis of the n-unprotected (r) -ester of (3 ) -amin0-3-arylpr0pi0nic acid esters
10/08/2009WO2009121785A2 Method for deracemization of enantiomer mixtures
10/08/2009WO2009094569A3 Method for the enzymatic kinetic resolution of acyloxyalkyl thiocarbonates used for the synthesis of acyloxyalkyl carbamates
10/07/2009EP1745136B1 Method for enzymatic preparation of (s)-3-cyano-5-methylhexanoic acid
10/07/2009EP1686114B1 Process for producing optically active 2-alkylcysteine, derivative thereof, and processes for production
10/07/2009CN101553573A Whole-cell catalytic system comprising a hydantoinase, a racemase and a carbamoylase
10/01/2009WO2009118750A1 Stereoselective hydrolysis for the resolution of racemic mixtures of (+/-) -cis-s-acetoxy-l- (4-methoxyphenyl) -4- (2-furyl) -2-azetidinone, (+/-) -cis-s-acetoxy-l- (4-methoxyphenyl) -4- (2-thienyl) -2-azetidinone, or
09/2009
09/30/2009EP2105507A1 Deracemisation of amines
09/30/2009EP1412323B1 Protected 3,5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and derivatives and method for the production and use thereof
09/30/2009CN101545002A Method for improving the concentration of substrate in biological resolution L-menthol reaction
09/23/2009EP2102353A2 Whole-cell catalytic system comprising a hydantoinase, a racemase and a carbamoylase
09/23/2009EP1383899B1 Enzymatic method for the enantioselective reduction of keto compounds
09/23/2009EP1070132B1 Recombinant l-n-carbamoylase derived from arthrobacter aurescens, and a method for producing l-amino acids by using the same
09/23/2009CN100542535C Preparation method of medicinal composition containing 1,3-oxathin cyclopentane nucleoside analogues
09/22/2009US7592476 Process for producing enantiopure β-amino acid derivatives, and enantiopure β-amino acid derivatives
09/16/2009CN101532007A Immobilized Serratia lipase, preparation method and application for catalyzing and splitting diltiazem chiral precursor
09/03/2009WO2009107821A1 Process for production of optically active carboxylic acid using esterase derived from thermophilic archaebacterium
09/02/2009EP1853719B1 Enzymatic transformation of a prostaglandin (bimatoprost) intermediate
09/02/2009CN101519683A Method for resolving and purifying chiral aromatic alcohol compound and partial intermediate products and final products thereof
09/01/2009US7582469 Method for enantioselectively opening oxetan-2-ones
09/01/2009US7582468 Process for preparing (2R,3S)-1,2-epoxy-3-(protected)amino-4-substituted butane and intermediates thereof
09/01/2009US7582454 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids
08/2009
08/27/2009US20090215132 Novel amide hydrolase gene
08/26/2009EP2092060A1 R-hnl random variants and their use for preparing optically pure, sterically hindered cyanohydrins
08/26/2009CN101517092A Method for producing optically active succinimide compound
08/26/2009CN101517088A Method for producing optically active 2-benzyloxycyclohexylamine
08/19/2009EP1600499B1 Process for producing lactonase and utilization thereof
08/19/2009CN101512005A Process for preparation of optically active N-protected 3 -aminopyrrolidine or optically active N-protected 3-aminopiperidine and the corresponding ketones by optical resolution of the racemic amine m
08/19/2009CN100529097C Enzymatic synthesis of enatiopure intermediates by means of cholesterolesterase from yeasts
08/13/2009WO2009099140A1 Process for production of optically active indoline-2-carboxylic acid or derivative thereof
08/12/2009EP2087127A2 Method for the enantioselective enzymatic reduction of secodione derivatives
08/12/2009EP1367132B1 Process for preparation of optically active propoxyaniline derivatives
08/12/2009CN101503729A Enzymatic resolution method of dl 1-phenylethanol compounds
08/12/2009CN101503683A Magnetic nano particle immobilized Serratieae lipase, preparation and use
08/11/2009US7572606 Biosyntheses of salinosporamide A and its analogs and related methods of making salinosporamide A and its analogs
08/11/2009CA2183449C Enzymatic resolution of substituted 2-methyl-propionic acid
08/05/2009CN101501189A Proteins with esterase activity
08/04/2009US7569375 obtained from Rhodococcus; biocatalyst; stereospecific alcohol dehydrogenase activity in the oxidation of secondary alcohols or the reduction of ketones
08/04/2009CA2253977C Process for the preparation of amino alcohols and derivatives thereof
07/2009
07/30/2009WO2009094569A2 Method for the enzymatic kinetic resolution of acyloxyalkyl thiocarbonates used for the synthesis of acyloxyalkyl carbamates
07/30/2009CA2706575A1 Enantiomerically resolving acyloxyalkyl thiocarbonates used in synthesizing acyloxyalkyl carbamate prodrugs
07/29/2009EP1994162B1 Process for the preparation of optically active 5-substituted 2-oxazolidinones from racemic epoxides and cyanate employing a halohydrin dehalogenase
07/23/2009WO2009091054A1 Novel hydrogen peroxide-forming nadh oxidase, and dna encoding the same
07/15/2009EP2077987A1 Mandelic acid derivatives and preparation thereof
07/14/2009CA2143545C Process for producing optically active 4-hydroxy-2-ketoglutaric acids
07/09/2009WO2008046328A8 A levorotatory lactonohydrolase producing strain and its use for producing chiral oxyacid
07/09/2009US20090176976 Nitrilases
07/08/2009CN100510098C Optically active, heteroaromatic beta-hydroxy esters, processes for their preparation from beta-keto esters and processes for the preparation of these beta-keto esters
07/01/2009EP2073933A1 Reaction system
06/2009
06/30/2009US7553652 Polypeptide having amidohydrolase activity capable of hydrolysing 3,3,3-trifluoro-2-hydroxy-2-methyl propionamide in form of the racemate or of an optically active isomer; obtainable from Klebsiella oxytoca, Pseudomonas, Rhodococcus opacus, Arthrobacter ramosus, Bacillus
06/30/2009CA2254693C Process for the preparation of aminoalcohol derivatives and their further conversion to (1r,4s)-4-((2-amino-6-chloro-5-formamido-4-pyrimidinyl)amino)-2-cyclopentenyl-1-methanol
06/25/2009US20090162906 Biocatalysts; mutant and/or chemically modified enzymes; stereoselectively hydrolyze an amino nitrile or cyanohydrin intermediate to produce the corresponding carboxylic acid; e.g. phenylglycinonitrile from benzaldehyde, potassium cyanide and ammonium chloride
06/18/2009WO2003000909A3 Methods for the manufacture of pure single enantiomer compounds and for selecting enantioselective enzymes
06/17/2009EP2071033A1 Method for producing optically active succinimide compound
06/17/2009EP2071032A2 The use of enzymatic resolution for the preparation of intermediates of pregabalin
06/17/2009EP2069517A1 Method for producing optically active 2-benzyloxycyclohexylamine
06/17/2009EP2069516A1 Specific hydrolysis of the n-unprotected (r) -ester of (3 ) -amin0-3-arylpr0pi0nic acid esters
06/10/2009EP1409667B2 Process for preparing variant polynucleotides
06/10/2009EP1129180B1 Chemically modified mutant serine hydrolases
06/03/2009EP2064331A1 Process for preparation of optically active n-protected 3 -aminopyrrolidine or optically active n-protected 3-aminopiperidine and the corresponding ketones by optical resolution of the racemic amine mixtures employing a bacterial omega-transaminase
06/03/2009EP1433857B1 Process for producing monomer
05/2009
05/28/2009WO2009006492A3 Stereoselective resolution of racemic amines
05/28/2009US20090137012 Process for producing lactonase and utilitzation thereof
05/28/2009US20090136994 Polypeptide having amidase activity and gene thereof
05/20/2009CN101437955A Process for the preparation of optically active 5-substituted 2-oxazolidinones from racemic epoxides and cyanate employing a halohydrin dehalogenase
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