Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
09/2010
09/14/2010US7795004 Process for the racemization of optically active secondary alcohols with the use of two alcohol dehydrogenases
09/14/2010CA2536144C Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament
09/10/2010WO2010100195A1 Method for stereoselectively and enzymatically reducing keto compounds
09/10/2010CA2753634A1 Process for the stereoselective enzymatic reduction of keto compounds
09/08/2010EP2226386A1 Method for stereoselective enzymatic reduction of keto compounds
09/08/2010CN101827944A Process for the preparation of an enantiomerically and/or diastereomerically enriched ester, thioester, alcohol or thiol
09/08/2010CN101338287B Bacillus subtilis esterase and application thereof for producing 1-menthol
09/07/2010US7790436 Method for production of (1S)-3-chloro-1-(2-thienyl)-propan-1-ol using alcohol dehydrogenase from thermoanaerobacter
09/07/2010CA2354382C Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent-2-ene derivatives
09/02/2010WO2010098505A1 Process for producing novel optically active mandelic acid and derivative thereof
09/01/2010EP1179595B1 (r)-2-octanol dehydrogenases, methods for producing the enzymes, dna encoding the enzymes, and methods for producing alcohols using the enzymes
09/01/2010CN101821404A Microbial kinetic resolution of ethyl-3,4-epoxybutyrate
08/2010
08/26/2010US20100216214 hydrolysis of a hydroxyglutaryl nitrile to generate an ethyl 4-cyano-3-hydroxybutyrate; hydrolysis of a mandelonitrile to generate a mandelic acid; hydrolysis of phenyllactocyanonitrile to generate an (S)-phenyllactic acid
08/18/2010EP2218788A1 Process for the preparation of optically active cyclopentenones
08/17/2010US7776582 Optically enhanced chiral ionic liquids
08/12/2010US20100204503 Stereoselective Bioconversion of Aliphatic Dinitriles into Cyano Carboxylic Acids
08/11/2010CN101802207A enantioselective reduction
08/10/2010US7772240 used for the treatment of psychological disorders such as schizophrenia, anxiety, depression and bipolar disorder
08/10/2010US7771935 Combinatorial chemistry
08/05/2010US20100197934 Process for producing optically active alpha-methylcysteine derivative
08/05/2010US20100196970 Butynol I esterase
08/03/2010US7767683 Hydrogen succinate salts of trans-4-((1R, 3S)-6-chloro-3-phenylindan-1-YL)-1,2,2-trimethylpiperazine and the use as a medicament
08/03/2010CA2591818C Process for the preparation of optically active aminoalcohols
07/2010
07/29/2010DE102006039189B4 Enantioselektive Darstellung von aliphatischen azyklischen Estern und Ketonen Enantioselective preparation of aliphatic acyclic esters and ketones
07/20/2010US7759110 Rhodosporidium biosynthesis
07/20/2010CA2389250C Antibody catalysis of enantio- and diastereo-selective aldol reactions
07/15/2010WO2010081053A2 Transaminase polypeptides
07/14/2010EP1071807B1 Method for enzymatic enantiomer-separation of 3(r)- and 3(s)-hydroxy-1- methyl-4-(2,4, 6-trimethoxyphenyl)-1, 2,3,6- tetrahydro-pyridine or its carboxylic acid esters
07/13/2010US7754462 increases in the yield and selectivity; can be used as co-solvents to improve the solubility of educts and products
07/07/2010EP2203562A1 Process for the preparation of an enantiomerically and/or diastereomerically enriched ester, thioester, alcohol or thiol
07/01/2010WO2009121785A3 Method for deracemization of secondary alcohols
06/2010
06/30/2010CN101760499A Enzymatic production method of theanine
06/24/2010WO2010068994A1 Process for the production of chemicals
06/24/2010CA2747212A1 Process for the production of chemicals
06/23/2010CN1656230B Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates
06/23/2010CN101031531B Proess for producing an optically active 2-methyl-alkane-1-ols from the corresponding 2-methylalk-2-en-1-als, comprising the steps of carbonyl selective reductioin, antipode selective hydrogenation, l
06/17/2010WO2010067613A1 L-succinyl aminoacylase and process for producing l-amino acid using same
06/16/2010CN1934264B Process for preparing optically active amino acids using a whole-cell catalyst
06/16/2010CN1839124B Succinate and malonate salt of trans-4-(1R,3S)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament
06/10/2010WO2010064744A1 Mutant blocked in glycerol oxidaion pathway for producing 1,3-propanediol
06/09/2010EP1685248B1 Oxidoreductase from metschnikowia zobellii
06/09/2010EP1228087B1 Antibody catalysis of enantio- and diastereo-selective aldol reactions
06/09/2010CN1935977B Levo lactone hydrolase producing fungus, and its method for preparing chiral hydroxy acid
06/09/2010CN101250492B Agrobacterium strain and method for preparing left-lateral lactone compounds thereby
06/03/2010US20100136557 Methods and Compositions for Isolating Nucleic Acid Sequence Variants
06/02/2010CN101717810A Preparation method of D-serine by enzymatic conversion
06/01/2010US7727749 Stereoselective bioconversion of aliphatic dinitriles into cyano carboxylic acids
06/01/2010CA2157427C Oxazoloquinolinone derivatives, their preparation and their therapeutic application
05/2010
05/27/2010WO2010058577A1 Method for producing unsaturated aminocarboxylic acid derivative
05/26/2010EP1490501B1 Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates
05/25/2010USRE41356 Hepatitis C inhibitor tri-peptides
05/19/2010CN101709323A Method for producing R-mandelic acid with biocatalysis and separating and coupling method
05/19/2010CN101134943B Bacillus alcaligenes and method for preparing single enantiomer amygdalic acid
05/14/2010WO2010053050A1 O-alkylserine, and process for producing n-benzyl-o-alkylserine
05/11/2010US7713724 Hydantoin racemase
05/06/2010WO2010050516A1 Method for producing l-amino acid
05/05/2010CN1942587B Stereoselective bioconversion of aliphatic dinitriles into cyano carboxylic acids
05/05/2010CN101701243A Method for producing R-mandelic acid and derivates thereof by biocatalysis
04/2010
04/28/2010EP2179050A1 Microbial kinetic resolution of ethyl-3,4-epoxybutyrate
04/15/2010WO2009141362A3 Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester
04/15/2010US20100093797 Methods For Treatment Of Cognitive And Menopausal Disorders With D-Threo Methylphenidate
04/14/2010CN101693914A Process for preparing (R)-2-methylbutanoic acid and (R)-2-methylbutanoic acid ethyl ester via lipase resolution
04/13/2010US7695942 Aziding epichlorohydrin in presence of halohydrin dehalogenase to form alcohol
04/13/2010CA2432150C Glycosaminoglycans derived from k5 polysaccharide having high antithrombin activity and process for their preparation
04/08/2010US20100086986 Nitrilases and Methods for Making and Using Them
04/07/2010EP2171077A2 Enantioselective reduction
04/07/2010CN101153300B Method for splitting and producing D-tyrosine-15N by enzymatic method
03/2010
03/25/2010US20100075404 Processes for the digestion of colanic acid
03/25/2010CA2735769A1 Method for producing l-phenylephrine using an alcohol dehydrogenase of aromatoleum aromaticum ebn1 (azoarcus sp. ebn1)
03/23/2010CA2437312C Process for producing (3r,5s)-(e)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-3,5-dihydroxyhept-6-enic acid esters
03/23/2010CA2393617C Vitamin d precursors, method and intermediates
03/23/2010CA2196656C Method for the preparation of (±)-calanolide a and intermediates thereof
03/17/2010CN101671716A Method for manufacturing D-phenylalanine by bio-enzyme asymmetric transformation
03/17/2010CN101671664A Preparation method of immobilized aminoacylase and product and application thereof
03/10/2010EP1216304B1 Whole cell catalyst comprising a hydantoinase, a racemase and a carbamoylase
03/09/2010US7674614 Method of optically resolving racemic alcohols with a bicyclooxaoctane or a bicycooxaoctene resolving reagents
03/04/2010CA2735230A1 Hydrolases, nucleic acids encoding them and methods for making and using them
03/03/2010CN101659978A D-serine enzymatic conversion preparation method
02/2010
02/25/2010CA2734620A1 Production of l-ribose and other rare sugars
02/24/2010CN100591775C Method for preparing optical pure selenium - methyl selenium substituted cysteine by employing enzymatic resolution of racemic selenium- methyl selenium substituted cysteine
02/23/2010US7666659 via enzyme from Brettanomyces, Debaryomyces, Galactomyces, Ogataea, Pichia, Saccharomycopsis, Sporidiobolus, Sporobolomyces, Sterigmatomyces, Torulaspora, Trichosporon, Yamadazyma, Achromobacter, Cellulomonas, Devosia, Hafnia, Jensenia, Klebsiella, Micrococcus, Proteus, or Serratia
02/23/2010CA2347521C Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase
02/17/2010EP2154253A1 Process for producing optically active 2-alkyl-1,1,3-trialkoxycarbonylpropane
02/17/2010CN101649344A Biological preparation technology of D-lactamine
02/16/2010US7662610 using the lipase from Candida antarctica to contact ester to form an acid intermediate; hydrolyzing
02/11/2010US20100035928 Method Of Treating Attention Deficit Disorders With D-Threo Methylphenidate
02/09/2010US7659106 Non-homogeneous systems for the resolution of enantiomeric mixtures
02/02/2010US7655450 Efficient production of an optically active amino acid; Arthrobacter; culturing
01/2010
01/28/2010DE112008000311T5 Verfahren zum Auffangen eines L-Biphenylalanin-Verbindungssalzes und Verfahren zum Auffangen einer Biphenylalaninester-Verbindung unter Verwendung desselben Of the same method for collecting an L-biphenylalanine compound salt and method for collecting a biphenylalanine ester compound using
01/26/2010US7651849 Increased activity and stability at increased pH and temperature
01/26/2010CA2229312C Cleavage of optically active amides
01/21/2010US20100016627 Process for producing optically active 3-hydroxypropionic ester derivative
01/20/2010EP2145009A1 Process for enzymatic reduction of alkene derivatives
01/14/2010WO2010005003A1 Method for producing (1s,2r)-2-chloro-2-fluorocyclopropanecarboxylic acid
01/14/2010WO2010004577A1 Preparation of enantiomerically enriched gamma-nitro acid and pregabalin
01/14/2010US20100009426 synthetic or recombinant polypeptide having a nitrilase activity; have increased activity and stability at increased pH and temperature
01/12/2010US7645607 Method for producing optically active N-protected-propargylglycine
01/12/2010CA2399062C Stereoselective synthesis of nucleoside analogues
12/2009
12/30/2009WO2009158343A1 Stereoselective enzymatic synthesis of (s) or (r)-iso-butyl-glutaric ester
12/23/2009WO2009153325A1 Optical resolution of a mixture of enantiomers of butynol or butenol
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