Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
03/2014
03/26/2014CN103667088A Candida and method for preparing D-valine through microbial metabolism
03/26/2014CN103664976A Method for preparing cis-hexahydrofuro[2,3-B]furan-3-ol
03/26/2014CN101985647B Method for improving asymmetric conversion efficiency of (R)-phenyl glycol by recombination strains through cosubstrate coupling
03/25/2014US8680051 Method of ameliorating symptoms of type 1-diabetes using GABA related compounds and GLP-1/exendin-4 compounds
03/20/2014WO2014041372A1 Lipases, polynucleotides encoding them and their uses
03/19/2014CN103649324A Separation process
03/19/2014CN103649323A Separation process
03/12/2014CN103627776A Method for preparing S-2-(4-nitrobenzophenone) oxirane
03/12/2014CN102408289B Separation method of chiral medicament by applying protein functionalized magnetic nano-particles
03/05/2014CN103614450A Method for resolving DL-menthol through catalysis of lipase
03/05/2014CN103614449A Resolution method for Se-methylselenocysteine
02/2014
02/25/2014CA2583322C Processes for preparing optically active (s or r)-b-amino acid and optically active (r or s)-b-amino acid ester, and b-amino acid 2-alkoxyethyl ester and optically active (s or r)-b-amino acid 2-alkoxyethyl ester
02/19/2014CN103596924A Method for producing optically active alpha-substituted proline
02/18/2014CA2659300C Process for preparation of optically active n-protected 3-aminopyrrolidine or optically active n-protected 3-aminopiperidine and the corresponding ketones by optical resolution ofthe racemic amine mixtures employing a bacterial omega-transaminase
02/13/2014WO2014024886A1 Method for producing methyl jasmonate isomer composition having high epi-isomer content
02/12/2014CN103571908A Method for preparing chiral N-tert-butyloxycarboryl-3-hydroxypiperidine
02/11/2014US8647857 Processes for the digestion of colanic acid
02/11/2014CA2559186C Process for preparing optically active amino acids using a whole-cell catalyst
02/04/2014US8642836 Method of selectively producing male or female sterile plants
02/04/2014CA2580151C Stereoisomerically enriched .beta.-lactams using candida antarctica
01/2014
01/29/2014CN103540641A Method for producing valine
01/23/2014WO2014013179A1 Method for the enzyme synthesis of (7s)-1-(3,4-dimethoxy bicyclo[4.2.0]octa-1,3,5-triene 7-yl) n-methyl methanamine, and application to the synthesis of ivabradine and the salts thereof
01/22/2014EP2687506A1 Method for enzymatic synthesis of (7S)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-yl) N-methyl methanamine, and use for the synthesis of Ivabradine and the salts thereof
01/22/2014CN103534353A Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same
01/22/2014CN103534350A Novel transaminase showing high activity for glutamic acid, gene encoding same, and method for utilization thereof
01/22/2014CN101880695B Method for preparing (S)-naproxen by enzyme resolution of racemic naproxen ester
01/17/2014CA2820192A1 Enzymatic synthesis process for (7s)-1-(3,4-dimethoxy bicyclo[4.2.0]octa-1,3,5-triene 7-yl) n-methyl methanamine, and application to the synthesis of ivabradine and of its salts
01/15/2014EP2684953A1 Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same
01/09/2014US20140011224 Novel bacterial strain of achromobacter sp. mtcc 5605 and a highly enantioselective epoxide hydrolase isolated therefrom
12/2013
12/25/2013CN103468779A Preparation method of L-menthol
12/25/2013CN103468658A Enantioselective epoxide hydlrolase and method for preparing and enantiopure epoxide using the same
12/19/2013WO2013186540A1 Lactate production process
12/18/2013EP2674413A1 Process for the preparation of treprostinil and derivatives thereof
12/18/2013CN103450040A Synthesis method of D-threonine
12/18/2013CN102408288B Method for separating chiral drug by using protein-functionalized magnetic nanoparticles
12/04/2013CN102851238B Sphingobacterium and method for preparing levetiracetam acid by utilizing same
11/2013
11/28/2013WO2013174848A2 Improved process for the preparation of treprostinil and derivatives thereof
11/28/2013US20130316409 Nitrilases, Nucleic Acids Encoding Them and Methods for Making and Using Them
11/27/2013CN102796715B Tertiary alcohol ester hydrolase, encoding gene, carrier, engineering bacteria and application thereof
11/20/2013EP2261327B1 A group of novel enantioselective microbial nitrile hydratases with broad substrate specificity
11/14/2013WO2013117869A3 Method for enzymatically synthesizing (7s)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid or the esters thereof, and use in the synthesis of ivabradine and the salts thereof
11/13/2013CN102089439B Method for producing (1s,2r)-2-chloro-2-fluorocyclopropanecarboxylic acid
11/06/2013CN102286563B Method for preparing L-ornithine from immobilized enzyme
10/2013
10/30/2013CN101935639B Ene reductase gene, protein and application thereof
10/17/2013WO2013154066A1 Optical resolution method for bicyclic compound using enzyme
10/16/2013CN102660624B Alpha-hydroxy acid deracemisation method and strain
10/03/2013US20130261331 Process for producing optically active alpha-methylcysteine derivative
10/02/2013EP2643281A1 Preparation of isomerically pure substituted cyclohexanols
10/02/2013CN103333942A A synthetic method for (R)-praziquantel
09/2013
09/18/2013CN103305584A Method for splitting optically pure 2-octyl alcohol by adopting enzyme catalysis
09/18/2013CN103305583A Simple extraction of racemic p-methoxyphenyl glycidic acid methyl ester
09/11/2013CN102533921B Method and bacterial strains for preparing (S)-epichlorohydrin through microbial transformation
09/10/2013US8530213 Compositions and methods for using NADH oxidases
08/2013
08/29/2013WO2013126337A1 Process for resolving cyclopropyl diesters
08/27/2013CA2625834C Oxidoreductases for the stereoselective reduction of keto compounds
08/22/2013WO2013123240A1 Methods and compounds useful in the synthesis of orexin-2 receptor antagonists
08/14/2013EP2626428A2 Method for enzymatic synthesis of (7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid or the esters thereof, and use for the synthesis of ivabradine and the salts thereof
08/14/2013CN103243146A Enzymatic synthesis of ivabradine midbody and application in the synthesis of ivabradine and addition salts thereof
08/14/2013CN102102114B Preparation of pregabalin and related compounds
08/09/2013CA2805831A1 Enzymatic synthesis process for (7s)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid or of its esters and application of ivabradine and its salts to the synthesis
08/07/2013EP2623595A1 Novel transaminase showing high activity for glutamic acid, gene encoding same, and method for utilization thereof
08/07/2013EP2623593A1 Novel aminotransferase and gene encoding same, and use of the aminotransferase and the gene
08/07/2013CN103232992A Immobilized lipase and preparation method and application thereof
08/07/2013CN102628076B Preparation technology of chiral amino acid
08/06/2013US8501451 Nitrilases and methods for making and using them
07/2013
07/31/2013CN103224973A Method of fementing shrimp heads to prepare active substances, chitin and organic acidity calcium
07/31/2013CN102851216B Aspergillus fumigatus and its use in microbial preparation of (R,R)-3-phenylglcidol
07/31/2013CN102660470B Sinorhizobium fredii and its application in producing chiral alpha-hydroxy acid by biologically splitting alpha-hydroxy acid raceme
07/31/2013CN102533922B Method for catalyzing dynamic kinetic resolution of arylamine via racemization catalyst
07/25/2013WO2013011296A3 Separation process
07/24/2013CN102174633B Method for splitting ibuprofen
07/23/2013CA2529583C Oxidoreductase from pichia capsulata
07/11/2013US20130177949 Nitrilases
07/10/2013EP2612913A1 Novel hydrolase protein
07/10/2013CN103194520A Method for preparing 4-hydroxyl tetrahydropyran derivative with optical activity through enzymatic transesterification
06/2013
06/27/2013WO2013094499A1 METHOD FOR PRODUCING OPTICALLY-ACTIVE α-SUBSTITUTED-β-AMINO ACID
06/26/2013EP2607480A1 Asymmetric hydrolase and gene thereof
06/19/2013CN103160562A Method of synthetizing levo-praziquantel
06/19/2013CN101978055B Hydrogen peroxide-forming nadh oxidase and DNA encoding the same
06/12/2013CN102719378B Method for preparing (-) gamma-lactam by catalysis asymmetry of microorganism
06/12/2013CN102154432B Method for preparing rasagiline
06/11/2013US8460902 DNA encoding hydantoinase, DNA encoding N-carbamyl-L-amino acid hydrolase, recombinant DNA, transformed cell, method of producing protein, and method of producing optically active amino acid
06/06/2013WO2013081100A1 Adamantyl hydantoin compound
06/05/2013CN103140580A Novel aminotransferase and gene encoding same, and use of the aminotransferase and the gene
06/05/2013CN103131747A Method for synthesizing (S)-3-(4-hydroxyl phenyl)-3-methylamino propionic acid by using biological enzymes through chiral resolution
06/05/2013CN103131659A Organic solvent-resistant lipase, as well as encoding gene, producing strain and application thereof
06/05/2013CN103131649A Pseudomonas fluorescens and application in preparation of transform-4-aminomethyl-naphthenic acid thereof
05/2013
05/30/2013WO2013075239A1 Diterpene synthases and method for producing diterpenoids
05/30/2013CA2855171A1 Diterpene synthases and method for producing diterpenoids
05/23/2013WO2013073679A1 Method for producing (2r,4r)-monatin polyvalent metal salt crystals
05/22/2013CN103114122A Method for preparing trans-4-aminomethyl-naphthenic acid from Actioplanes sp.
05/10/2013WO2013030851A4 A novel bacterial strain of achromobacter sp. mtcc 5605 and a highly enantioselective epoxide hydrolase isolated therefrom
05/02/2013WO2013060292A1 R-praziquantel preparation method
05/02/2013US20130109719 Method of treating attention deficit disorders with d-threo methylphenidate
05/01/2013CN103074409A Method for splitting halogenated alpha-amino acid
05/01/2013CN101522892B Enantioselective epoxide hydlrolase and method for preparing an enantiopure epoxide using the same
05/01/2013CN101517088B Method for producing optically active 2-benzyloxycyclohexylamine
04/2013
04/24/2013CN102367430B Pseudoalteromonas sp.B3 and application thereof in biological oxidation of L-amino acid
04/24/2013CN102242085B Epoxy hydrolase, gene thereof and application thereof
04/24/2013CN101979527B Reductase, reductase gene, recombinant enzyme, preparation method of recombinant enzyme and application
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