Patents for C12P 41 - Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture (4,784)
03/2011
03/30/2011CN101993828A Method for improving transformation efficiency of (S)-phenyl glycol by coupling glucose-6-phosphate dehydrogenase and (S)-carbonyl reductase
03/30/2011CN101253262B New esterases and their use for processes for kinetic resolution of butinolesters
03/24/2011WO2011034126A1 Process for asymmetric synthesis of equol
03/24/2011US20110070630 Method for deracemization of enantiomer mixtures
03/23/2011EP2297090A1 Stereoselective enzymatic synthesis of (s) or (r)-iso-butyl-glutaric ester
03/22/2011CA2366637C Process for the preparation of prostaglandin precursors
03/17/2011US20110065168 Preparation of Pregabalin and Related Compounds
03/17/2011US20110065154 Deracemisation of Amines
03/16/2011EP2294207A2 Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester
03/16/2011CN101985647A Method for improving asymmetric conversion efficiency of (R)-phenyl glycol by recombination strains through cosubstrate coupling
03/16/2011CN101985609A Pseudomonas and method for performing microbial transformation on pregabalin intermediate by using same
03/10/2011US20110059503 Compositions of variant biocatalysts for preparing enantiopure amino acids
03/08/2011US7903553 Method, apparatus, edge router and system for providing QoS guarantee
03/03/2011US20110053957 Malonate salt of 4-((1r,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and uses of same
02/2011
02/23/2011EP2287322A1 A method of selectively producing male or female sterile plants
02/23/2011EP2287152A2 Process for producing optically active alpha-methylcysteine derivative
02/23/2011EP2069517B1 Method for producing optically active 2-benzyloxycyclohexylamine
02/23/2011EP1963516B1 Method for the enantioselective enzymatic reduction of hydroxyketo compounds
02/23/2011EP1840218B1 Process for production of optically active (S)- or (R)-beta-amino acids and optically active (R)- or (S)-beta -amino acid esters, and optically active (S)- or (R)-2-alkoxyethyl esters of beta-amino acids.
02/23/2011CN101981197A Method for deracemization of enantiomer mixtures
02/23/2011CN101979527A Reductase, reductase gene, recombinant enzyme, preparation method of recombinant enzyme and application
02/22/2011USRE42164 Hepatitis C inhibitor tri-peptides
02/16/2011CN101978055A Novel hydrogen peroxide-forming nadh oxidase and DNA encoding the same
02/16/2011CN101974605A Method for preparing D-cystine by using microorganism enzymic method to split DL-cysteine
02/16/2011CN101974604A Method for preparing paroxetine intermediate through enzymatic resolution in ionic liquid
02/16/2011CN101974603A Method for producing D-alpha-hydroxybutyric acid
02/16/2011CN101974602A Method for preparing (R)-type chiral aryl secondary alcohol
02/15/2011US7888105 Enzymatic process for stereo-selective preparation of chemical compounds in hydrofluorocarbon solvents
02/09/2011CN101967489A Epoxide hydrolase gene, vector and engineering bacteria and application thereof
02/09/2011CN101967460A Bacillus alcaligenes and method for preparing D-para-hydroxybenzene aminoacetic acid by utilizing same
02/08/2011CA2563307C Stereoselective bioconversion of aliphatic dinitriles into cyano carboxylic acids
02/03/2011WO2011013340A1 Method for producing optically active 3-substituted glutaric acid monoamide
02/02/2011EP1481068B1 A method of selectively producing male or female sterile plants
02/01/2011CA2479705C Novel carbonyl reductase, gene encoding the same, and process for producing optically active alcohols using the same
02/01/2011CA2372097C Epoxide hydrolases of aspergillus origin
01/2011
01/26/2011EP2278017A1 A method of selectively producing male or female sterile plants
01/20/2011WO2010081053A3 Transaminase polypeptides
01/12/2011EP1287155B2 Enzymatic conversion of epoxides
01/05/2011EP1118674B1 Process for producing optically active tropinone monocarboxylic acid derivative
01/05/2011CN101939444A Process for production of optically active indoline-2-carboxylic acid or derivative thereof
01/05/2011CN101935639A Ene reductase gene, protein and application thereof
01/05/2011CN101935305A Trans-1(6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine
12/2010
12/29/2010WO2010151593A1 Sterospecific carbonyl reductases
12/29/2010EP2267144A2 Whole-cell catalytic system comprising a hydantoinase, a racemase and a carbamoylase
12/23/2010US20100324291 Processes for 4-((1r,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine or a salt thereof
12/22/2010CN101921822A Fermentation production method of S-adenosylmethionine and separation method of D-methionine
12/22/2010CN101921742A (+) gamma-lactamase with activity on splitting racemate gamma-lactam as well as coded gene and application thereof
12/15/2010EP2261327A2 A group of novel enantioselective microbial nitrile hydratases with broad substrate specificity
12/15/2010EP2069516B1 Specific hydrolysis of the n-unprotected (r) -ester of (3 ) -amin0-3-arylpr0pi0nic acid esters
12/15/2010CN101914605A Synthesis method of N-fluorenylmethyloxycarbonyl-2-methyltryptophan
12/15/2010CN101333554B Method for producing D-lactic acid by enzyme resolution of D,L-lactic Acid
12/14/2010CA2591566C Process for the preparation of an aminoalcohol
12/08/2010EP2258840A1 Methods for producing enantiomerically pure alpha-substituted carboxylic acids
12/08/2010EP2257635A2 Process for the deracemization of secondary alcohols
12/08/2010CN101906457A Method for preparing R-adrenaline by performing biologically asymmetric transformation
12/08/2010CN101143892B Method for resolving enantiomer by enzyme catalysis
11/2010
11/30/2010CA2513440C Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane
11/25/2010WO2010134642A1 Protein complex that catalyses asymmetric oxidation and method for preparing same
11/24/2010EP2077987B1 Mandelic acid derivatives and preparation thereof
11/24/2010EP1608746B1 Thermally stable amidases
11/24/2010CN101892283A Method for catalytically preparing optically pure (S)-(+)-2-phenylpropionic acid with Rhodococcus ruber 4.1187
11/18/2010US20100293666 Method of selectively producing male or female sterile plants
11/18/2010US20100291643 Method for producing enationmerically pure d-ppt
11/17/2010EP2251431A1 Process for production of optically active indoline-2-carboxylic acid or derivative thereof
11/17/2010EP2250143A2 Method for the enzymatic kinetic resolution of acyloxyalkyl thiocarbonates used for the synthesis of acyloxyalkyl carbamates
11/17/2010EP1727908B1 Process for preparing optically active amino acids using a whole-cell catalyst
11/17/2010CN101889081A Ketoreductase polypeptides and uses thereof
11/17/2010CN101886110A New method for splitting photoactive tert-leucine
11/17/2010CN101886063A Esterase with racemic phenyl glycidyl ester split activity, encoding gene and application thereof
11/16/2010CA2455797C Protected 3.5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production and the use
11/10/2010CN101880695A Method for preparing (S)-naproxen by enzyme resolution of racemic naproxen ester
11/10/2010CN101284769B Synthetic method for mainly intermediate compounds of anti-hypertensive drug aliskiren
11/03/2010EP2246424A1 Novel hydrogen peroxide-forming nadh oxidase, and dna encoding the same
11/03/2010CN101875959A Method for preparing abacavir chiral intermediate by biological split
11/03/2010CN101875607A (2S, 8Z)-2-butanoyloxy-8-heptadecene and preparation method thereof
11/03/2010CN101220336B Saccharomycete with stereoselectivity lipase liveness and application in producing S- type betaxolol hydrochloride with biological split method thereof
11/02/2010US7824899 Preparation of enantiomerically enriched amines and amides by enzymatic resolution using a sulfonylacetic acid ester as acyl donor
10/2010
10/28/2010WO2010123067A1 Process for production of (s)-1-substituted propan-1-ol derivative
10/27/2010CN101870984A RSP_2728 esterase mutant genes obtained by directed evolution and application of esterase in methyl mandelate resolution reaction
10/26/2010USRE41894 Hepatitis C inhibitor tri-peptides
10/26/2010CA2393343C Nadh oxidase from lactobacillus
10/26/2010CA2341345C Enzyme-catalyzed racemic cleavage of primary amines
10/20/2010EP1613762B1 Process for producing enantiopure beta-amino acid derivatives, and enantiopure beta-amino acid derivatives
10/19/2010US7816119 tosylating 3,4-dihydroxybutanenitrile by reacting with dibutyltinoxide, p-toluene sulphonyl chloride and a base, resoluting the resulting racemic 3-hydroxy-4-tosyloxybutanenitrile with an acetylating agent in the presence of lipase in an organic solvent
10/19/2010CA2396661C Method for producing optically active amines
10/14/2010WO2010068756A3 Process for manufacture of optically active 2-(acyloxymethyl)-1, 3 oxathiolanes
10/14/2010US20100261251 Microbial kinetic resolution of ethyl-3,4-epoxybutyrate
10/13/2010EP1633779B1 Oxidoreductase from pichia capsulata
10/13/2010CN101565685B Gene recombination bacterium and application thereof in preparing chiral pure acetoin and 2,3-butanediol
10/12/2010US7811804 synthetic or recombinant polypeptide having a nitrilase activity; have increased activity and stability at increased pH and temperature
10/12/2010CA2338946C Hepatitis c inhibitor tri-peptides
09/2010
09/30/2010WO2010111622A2 Amidases and methods of their use
09/30/2010US20100248337 PROCESS FOR THE PRODUCTION OF (s)-5-CHLORO-2-ISOPROPYLPENT-4-ENOIC ACID ESTERS
09/29/2010CN101845476A Method for preparing L-tertiary leucine compound by two enzyme system
09/28/2010US7803606 Method for the production of flavor-active terpenes
09/28/2010US7803586 Chemical Process
09/22/2010EP1712627B1 Polypeptide having amidase activity and gene thereof
09/15/2010CN101831483A Preparation method of L-methionine
09/15/2010CN101831482A Application of nanofiltration membrane in splitting D,L-amino acid by using acyltransferase or D-amino acylase
09/15/2010CN101092641B Process for the preparation of enantiomerically enriched amines and amides by enzymatic resolution
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