| Patents for C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: (2,334) |
|---|
| 05/14/2008 | EP1390023B1 Pharmaceutical salts of 1-phenyl-3-dimethylamino-propane compounds |
| 05/14/2008 | CN100387600C N-substituted hydromorphones and the use thereof |
| 05/07/2008 | EP1485051B1 Method of administering buprenorphine to treat depression |
| 04/30/2008 | CN101171253A Hydrocodone polymorphs |
| 04/23/2008 | EP1913001A2 (r)-n-methylnaltrexone, processes for its synthesis and its pharmaceutical use |
| 04/23/2008 | EP1476141B1 Tamper-resistant transdermal opioid delivery devices |
| 04/09/2008 | CN100379741C Process for the preparation of quaternary n-alkyl morphinan alkaloid salts |
| 04/02/2008 | CN101155814A Crystals of morphinan derivative and process for producing the same |
| 03/27/2008 | WO2008036980A1 Transdermally deliverable buprenorphine prodrugs and abuse-resistant compositions thereof |
| 03/27/2008 | US20080076789 Transdermally deliverable opioid prodrugs, abuse-resistant compositions and methods of using opioid prodrugs |
| 03/27/2008 | CA2663515A1 Transdermally deliverable buprenorphine prodrugs and abuse-resistant compositions thereof |
| 03/26/2008 | EP1439179B1 New oripavine derivatives and their uses as medicines |
| 03/26/2008 | CN101151266A Method for the catalytic production of hydrocodone, hydromorphone, and derivatives thereof |
| 03/26/2008 | CN101151250A Processes for preparing morphinans and intermediates thereof |
| 03/25/2008 | US7348430 Reacting an alcohol of a 4,5-epoxymorphinan compound with benzophenone and potassium tert-alkylate, adding dimethyl sulfate or acetic anhydride to produce hydrocodone and dihydrocodeinone enol acetate; the ketone undergoes instantaneous conversion to the corresponding enolate |
| 03/19/2008 | EP1899351A1 Method for separation and purification of naltrexone by preparative chromatography |
| 03/13/2008 | US20080064712 17-allyl-4,5 alpha -epoxy-3-methoxy-14 beta -(3-phenylpropyloxy)morphinan-6-one with various substituents in Position 3 show higher analgesic activity than their 14-hydroxy analogues; opioid antagonists |
| 03/06/2008 | US20080058502 Method for preparing microparticles having a selected polymer molecular weight |
| 03/05/2008 | EP1893616A2 A new synthetic route to 14-hydroxyl opiates through 1-halo-thebaine or analogs |
| 03/05/2008 | CN101137658A Antipruritic agent for pruritus caused by multiple sclerosis |
| 02/21/2008 | WO2008022285A1 Preparation and utility of opioid analgesics |
| 02/21/2008 | US20080045716 preparing a 6-oxo-14-hydroxy- Delta 7-morphinane comprising oxidizing a 6-methoxy-N-methyl- Delta 6, Delta 8-morphinane; useful in the preparation of opiate alkaloids; utilise such intermediates in the synthesis of morphinane compounds |
| 02/21/2008 | US20080045715 Preparation of Opiate Analgesics by Reductive Alkylation |
| 02/21/2008 | US20080045558 opiod and/or N-methylaspartic acid receptor modulators, used for the treatment and/or management of pain, neurodegenerative diseases, drug abuse and dependence, vision defects, or as muscle relaxants, antitussive and anxiolytic agents |
| 02/21/2008 | CA2661302A1 Preparation and utility of opioid analgesics |
| 02/20/2008 | EP1889848A1 6,7-unsaturated-7-carbamoyl substituted morphinan derivative |
| 02/20/2008 | CN101125137A Pharmaceutical salts |
| 02/13/2008 | CN100368414C Morphinan derivatives the quaternary ammonium salts thereof substituted in position 14, method for production and use thereof |
| 02/06/2008 | CN101119728A Indolomorphinan derivative having carboxy in 6'-position |
| 01/30/2008 | CN101115757A Method for purifying noroxymorphone compounds |
| 01/29/2008 | US7323565 Using complex catalyst containing transition metal and phosphine |
| 01/29/2008 | CA2256336C Quinolinomorphinan derivative and medical use thereof |
| 01/22/2008 | US7321038 Method for the catalytic production of hydrocodone and hydromorphone |
| 01/22/2008 | US7320984 Administering 4,5 alpha -epoxy-6 beta -(3,4-dihydro-2H-benzo[1,4]thiazino)-3-methoxy-17-methyl-morphinan; for urinary frequency, therapeutic or prophylactic effect and of which side effects are improved |
| 01/02/2008 | EP1873158A1 Crystals of morphinan derivative and process for producing the same |
| 01/02/2008 | EP1871775A1 Hydromorphone polymorphs |
| 01/02/2008 | EP1871774A1 Method for the catalytic production of hydrocodone, hydromorphone, and derivatives thereof |
| 12/26/2007 | EP1870413A1 Antipruritic agent for pruritus caused by multiple sclerosis |
| 12/26/2007 | CN101092397A Structure modified compound of sinomenine, and prepartion method |
| 12/20/2007 | US20070293676 Method for Separation and Purification of Hydrocodone by Preparative Chromatography |
| 12/19/2007 | CN101090722A 镇痛剂 Analgesics |
| 12/12/2007 | EP1864987A2 Methods for making 3-O protected morphinones and 3-O-protected morphinone dienol carboxylates |
| 12/12/2007 | EP1687310B1 Method for the catalytic production of hydrocodone and hydromorphone |
| 12/06/2007 | US20070281958 Preparation of oxycodone |
| 12/06/2007 | US20070281957 Crystalline Forms of Levorphanol |
| 12/05/2007 | EP1861406A2 Hydrocodone polymorphs |
| 12/05/2007 | EP1861373A2 Processes for preparing morphinans and intermediates thereof |
| 12/05/2007 | CN100352431C Pharmaceutical salts |
| 11/22/2007 | WO2007103105A3 Processes for preparing morphinan-6-one products with low levels of alpha, beta-unsaturated ketone compounds |
| 11/15/2007 | US20070265293 Opioid antagonists; lyophilization |
| 11/07/2007 | EP1851226A1 Method for purifying noroxymorphone compounds |
| 11/07/2007 | EP0915094B1 Morphinane derivatives and medicinal use thereof |
| 11/01/2007 | WO2007124114A2 Stereoselective reduction of a morphinone |
| 10/31/2007 | CN101065384A Method for separation and purification of hydrocodone by preparative chromatography |
| 10/25/2007 | US20070248667 Tannate Compositions and Methods of Use |
| 10/25/2007 | DE202005021371U1 Oxycodonhydrochlorid mit weniger als 25 ppm 14-Hydroxycodeinon Oxycodone hydrochloride with less than 25 ppm 14-hydroxycodeinone |
| 10/25/2007 | CA2649360A1 Mono and di-substituted oxycodone compounds and compositions |
| 10/24/2007 | EP1562952B1 Method for the catalytic production of hydrocodone and hydromorphone |
| 10/23/2007 | US7285665 Process for the preparation of quaternary N-alkyl morphinan alkaloid salts |
| 10/18/2007 | US20070241065 Extraction of Alkaloids for Opium |
| 10/17/2007 | EP1843768A2 Substituted morphinans and methods of their use |
| 10/09/2007 | US7279579 Polymorphic forms of naltrexone |
| 10/04/2007 | WO2007110637A1 Method for extracting target alkaloid using an ionic liquid as extracting solvent |
| 10/03/2007 | EP1838714A1 Methods of treating pain |
| 10/03/2007 | EP1838317A1 Analgesic conjugates |
| 09/26/2007 | EP1837396A1 Salutaridine reductase and morphine biosynthesis |
| 09/26/2007 | EP1837022A1 Indolomorphinan derivative having carboxy in 6'-position |
| 09/20/2007 | WO2006084412A9 Method for purifying noroxymorphone compounds |
| 09/20/2007 | US20070219373 Preparation of oxycodone |
| 09/19/2007 | EP1834634A2 Pharmaceutical multiple-unit composition |
| 09/13/2007 | WO2007103105A2 Processes for preparing morphinan-6-one products with low levels of alpha, beta-unsaturated ketone compounds |
| 09/13/2007 | CA2644095A1 Processes for preparing morphinan-6-one products with low levels of alpha, beta-unsaturated ketone compounds |
| 09/12/2007 | CN101033228A Method of preparing 14-hydroxy-7,8-dihydromorphone |
| 09/11/2007 | US7267968 Microbial n-and o-demethylation of a thebaine derivative |
| 09/07/2007 | WO2007098860A1 New morphine compounds for pharmaceutical compositions |
| 09/05/2007 | EP1829878A1 New morphine derivatives and pharmaceutical compositions containing the same |
| 09/04/2007 | US7265226 Interact with opoid receptors; decreasing metabolic rates of the phenolic piperidines by amidation, imidation, or forming a formamide, a hydroxyamidine or a thioamide; analgesics, anticonvulsants, antitussive agents; diarrhea, drug addiction |
| 08/30/2007 | US20070203165 Compounds and methods for lowering the abuse potential and extending the duration of action of a drug |
| 08/29/2007 | CN101027307A Preparation of opiate analgesics by reductive alkylation |
| 08/23/2007 | US20070197572 Oxycodone polymorphs |
| 08/22/2007 | EP1820505A1 Analgesic |
| 08/16/2007 | US20070191595 6-Monoacetyl morphine compounds, derivatized at either the C-3, the C-6, or the nor position with a carrier or label such as keyhole limpet hemocyanin, bovine thyroglobulin, bovine serum albumin, or aminodextran; useful for detecting drugs of abuse in biological samples |
| 08/07/2007 | CA2270955C Pharmaceutical composition containing morphinan derivative for treating drug dependence |
| 08/02/2007 | US20070179169 Oxycodone hydrochloride having less than 25 PPM 14-hydroxycodeinone |
| 08/01/2007 | CN101010006A Herbicide combinations comprising special ketoenoles |
| 07/26/2007 | WO2007062184A3 Processes for reducing contaminating michael acceptor levels in oxycodone and other compositions |
| 07/25/2007 | EP1810973A1 6-monoacetylmorphine derivatives useful in immunoassay |
| 07/25/2007 | CN1328280C Tetrandrine and tetrandrine compound, synthesis and uses thereof |
| 07/19/2007 | WO2007081506A1 The use of oripavine as a starting material for buprenorphine |
| 07/19/2007 | CA2636271A1 The use of oripavine as a starting material for buprenorphine |
| 07/18/2007 | EP1807433A1 Method for separation and purification of hydrocodone by preparative chromatography |
| 07/17/2007 | CA2389235C Controlled release hydrocodone formulations |
| 07/11/2007 | EP1204414B1 Use of morphinan derivates as medicines |
| 07/10/2007 | CA2427815C Controlled release hydrocodone formulations |
| 07/04/2007 | EP1803724A1 N-substituted hydromorphones and the use thereof |
| 06/28/2007 | WO2007072749A1 Antitussive agent |
| 06/20/2007 | CN1984912A 有丝分裂驱动蛋白抑制剂 Mitotic kinesin inhibitors |
| 06/19/2007 | US7232829 Analgesics; anticonvulsants; hypotensive agents; brain damage; antiarrhythmia agents; opioid receptors |
| 06/16/2007 | CA2571093A1 6-monoacetylmorphine derivatives useful in immunoassay |
| 06/13/2007 | EP1794165A1 Preparation of opiate analgesics by reductive alkylation |