Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
Patents for C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: (2,334)
01/2013
01/17/2013US20130018190 Stereoselective reduction of a morphinone
01/17/2013US20130017255 Tamper Resistant Dosage Form Comprising an Adsorbent and an Adverse Agent
01/17/2013CA2841169A1 Orvinol and thevinol derivatives useful in the treatment of drug and alcohol abuse
01/15/2013US8354534 Selective opioid compounds
01/08/2013US8350042 Antiviral compounds for the treatment of HCV infection
01/08/2013CA2501389C Remedies or preventives for frequent urination or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group
01/03/2013US20130005977 Oxycodone Hydrochloride Having Less Than 25 PPM 14-Hydroxycodeinone
01/03/2013US20130005755 Peripherally Acting Opioid Compounds
01/02/2013CN102002049B Antigen and preparation method and application thereof
01/02/2013CN101340911B Antitussive agent
01/01/2013US8343992 Synthesis of R-N-methylnaltrexone
12/2012
12/27/2012US20120330017 Process for preparing oxymorphone, naltrexone, and buprenorphine
12/26/2012CN102838607A Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone
12/25/2012US8338444 Opioid salts and formulations exhibiting anti-abuse and anti-dose dumping properties
12/25/2012US8338442 Remedies for psychoneurosis
12/12/2012CN102816167A Process for reducing contaminating michael acceptor levels in oxycodone and other compositions
12/11/2012US8329720 Opioid salts and formulations exhibiting abuse deterrent and anti-dose dumping properties
12/06/2012WO2012163796A1 Crystalline, anhydrous forms of oxymorphone hydrochloride
12/06/2012CA2837233A1 Crystalline, anhydrous forms of oxymorphone hydrochloride
12/05/2012EP2529739A1 Therapeutic or prophylactic agent for biliary diseases
11/2012
11/29/2012US20120302591 Methods of using 8-carboxamido-2,6-methano-3-benzazocines
11/28/2012CN102803267A Preparation of 6-alpha-amino n-substituted morphinans by catalytic hydrogen transfer
11/27/2012US8318937 Preparation of opiate analgesics by reductive alkylation
11/27/2012US8318936 Method for producing N-methylnaltrexone bromide
11/27/2012CA2586181C Analgesic
11/22/2012US20120295834 Opioid Prodrugs with Heterocyclic Linkers
11/21/2012CN101965187B Crystalline micropowder particles
11/20/2012US8314237 Preparation of 10-keto morphinans by benzylic oxidation
11/15/2012WO2012151669A1 Process for the preparation of morphine analogs via metal catalyzed n-demethylation/functionalization and intramolecular group transfer
11/15/2012CA2833282A1 Process for the preparation of morphine analogs via metal catalyzed n-demethylation/functionalization and intramolecular group transfer
11/13/2012US8309727 Opiate reduction utilizing catalytic hydrogen transfer reaction
11/08/2012WO2012149633A1 Processes and intermediates in the preparation of morphine analogs via n-demethylation of n-oxides using cyclodehydration reagents
11/08/2012US20120283444 Process for the preparation of morphine analogs via metal catalyzed n-demethylation/functionalization and intramolecular group transfer
11/08/2012US20120283443 Processes and Intermediates in the Preparation of Morphine Analogs via N-Demethylation of N-Oxides Using Cyclodehydration Reagents
11/08/2012CA2833283A1 Processes and intermediates in the preparation of morphine analogs via n-demethylation of n-oxides using cyclodehydration reagents
10/2012
10/25/2012US20120270894 Controlled Release of Phenolic Opioids
10/24/2012CN101208344B (R)-N-methylnaltrexone, processes for its synthesis and its pharmaceutical use
10/23/2012US8293906 Processes for the alkylation of norbuprenorphine with reduced impurity formation
10/18/2012US20120264775 Oligomer-Opioid Agonist Conjugates
10/18/2012US20120263788 Controlled release hydrocodone formulations
10/16/2012US8288547 N-methylnaltrexone zwitterion
10/11/2012US20120259118 Low abuk oxycodone, its salts and methods of making same
10/11/2012US20120258981 Process for the Synthesis of Quaternary Amine Compounds
10/11/2012DE112010001980T5 Synthese von Morphin und Verwandten Derivaten Synthesis of morphine and relatives derivatives
10/10/2012CN102721756A Synthesis of (R)-N-methylnaltrexone
10/10/2012CN102716101A Controlled release hydrocodone formulations
10/03/2012CN102711759A Therapeutic or prophylactic agent for biliary diseases
10/02/2012CA2674424C Hydromorphinone and hydrocodeinone compositions and methods for their synthesis
09/2012
09/27/2012US20120245193 PERIPHERIALLY ACTING μ OPIOID ANTAGONISTS
09/26/2012CN102695545A Compositions comprising enzyme-cleavable ketone-modified opioid prodrugs and optional inhibitors thereof
09/25/2012US8273888 Process for the preparation of 6-alpha-hydroxy-N-alkylated opiates
09/25/2012US8273887 Processes for synthesis of opiate alkaloid derivatives
09/18/2012US8269006 Processes for the selective amination of ketomorphinans
09/18/2012CA2451133C Therapeutic agent for sepsis
09/13/2012US20120230916 Compositions Comprising Enzyme-Cleavable Ketone-Modified Opioid Prodrugs and Optional Inhibitors Thereof
09/06/2012US20120226043 Method for the n-demethylation of n-methyl heterocycles
09/06/2012US20120225902 Methods for making 3-o-protected morphinones and 3-o-protected morphinone dienol carboxylates
09/05/2012CN1960994B Process for preparing oxycodone hydrochloride having 14-hydroxycodeinone less than 25 ppm
09/05/2012CN1514729B Sustained-release analgesic compounds
09/05/2012CN101686977B Therapeutic or prophylactic agent for dyskinesia
09/04/2012US8258298 Synthesis of morphine-6-glucuronide or one of the derivatives thereof
08/2012
08/28/2012US8252929 8-carboxamido-2,6-methano-3-benzazocines
08/28/2012US8252928 Processes for the synthesis of five and six membered heterocyclic rings
08/28/2012CA2561509C Anti-itching agent
08/23/2012WO2012025213A3 Novel therapeutic compounds
08/23/2012WO2011154827A3 Transition metal-catalyzed processes for the preparation of n-allyl compounds and use thereof
08/16/2012US20120209002 Process for reducing the 6-keto group of a morphinan alkaloid to the 6-hydroxy group by hydrogenation
08/07/2012US8236957 Process for making morphinan-6α-ols
08/02/2012US20120196888 Process for preparing oxymorphone, naltrexone, and buprenorphine
08/01/2012EP2480555A2 Methods for producing hydrocodone, hydromorphone or a derivative thereof
07/2012
07/31/2012US8232398 Recycling process for increasing the yield of opiate alkaloid derivatives
07/31/2012US8232397 Processes for the production of buprenorphine with reduced impurity formation
07/31/2012US8232396 Processes for the synthesis of opiates alkaloids with reduced impurity formation
07/31/2012US8231898 Controlled release hydrocodone formulations
07/25/2012EP2477984A1 A method for the n-demethylation of n-methyl heterocycles
07/24/2012US8227608 Processes for increasing the yield of opiate alkaloid derivatives
07/24/2012US8227483 Polymorphs of 6-beta-naltrexol
07/19/2012WO2012096887A2 Compositions comprising enzyme-cleavable oxycodone prodrug
07/19/2012WO2012054566A3 6-amido derivatives of 4,5a-epoxymorphinans for treatment of pain
07/19/2012US20120184536 Compositions comprising specific ugt inhibitors and methods of use thereof
07/19/2012CA2814763A1 Compositions comprising enzyme-cleavable oxycodone prodrug
07/18/2012EP2475429A1 Compositions comprising enzyme-cleavable ketone-modified opioid prodrugs and optional inhibitors thereof
07/18/2012CN102584840A Method for preparing nalmefene compound
07/17/2012US8222267 Methods of converting a patient's treatment regimen from intravenous administration of an opioid to oral co-administration of morphine and oxycodone using a dosing algorithm to provide analgesia
07/12/2012US20120178773 Compositions Comprising Enzyme-Cleavable Oxycodone Prodrug
07/12/2012US20120178772 Compositions Comprising Enzyme-Cleavable Oxycodone Prodrug
07/11/2012CN102573845A Novel dicarboxylic acid linked amino acid and peptide prodrugs of opioids and uses thereof
07/11/2012CN102558190A (R)-N-brooethyl naltrexone crystal form compound and preparation method, combination and application thereof
07/11/2012CN102558189A Refining method of methyhaaltrexone bromide
07/11/2012CN102558188A Preparation method of methyhaaltrexone bromide
07/10/2012US8217175 Preparation of oxymorphone from oripavine
07/05/2012US20120172387 Opioids for the treatment of the restless leg syndrome
07/04/2012CN101346384B Processes for reducing contaminating michael acceptor levels in oxycodone and other compositions
07/03/2012US8211905 Opioid salts and formulations exhibiting anti-abuse and anti-dose dumping properties
06/2012
06/27/2012EP2467384A1 Process for reducing the 6-keto group of a morphinan alkaloid to the 6-hydroxy group by hydrogenation
06/20/2012CN1407884B Controlled release hydrocodone formulations
06/14/2012US20120149900 Fluorine containing compounds and methods of use thereof
06/12/2012US8198446 Crystalline micropowder particles
06/12/2012US8198444 Methods for making 3-O-protected morphinones and 3-O-protected morphinone dienol carboxylates
06/07/2012US20120142925 Process for the demethylation of oxycodone and related compounds
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