| Patents for C07D 489 - Heterocyclic compounds containing 4ah-8, 9 c- iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: (2,334) |
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| 08/01/2006 | US7084150 pain therapy, transdermal application |
| 07/27/2006 | US20060167258 Production of opioid analgesics |
| 07/13/2006 | WO2006073396A1 Analgesic conjugates |
| 07/13/2006 | US20060155130 Method for the catalytic production of hydrocodone, hydromorphone, and derivatives thereof |
| 07/13/2006 | CA2593165A1 Analgesic conjugates |
| 07/12/2006 | CN1263760C Novel buprenorphine ester derivatives and process for preparing the same and medical composition with long-acting analgesic effect |
| 07/11/2006 | CA2244256C Antipruritic |
| 07/04/2006 | US7071336 Process for manufacturing opioid analgesics |
| 07/04/2006 | CA2233285C Pyrazolopyrimidines as crf receptor antagonists |
| 06/29/2006 | WO2006066362A1 Methods of treating pain |
| 06/29/2006 | US20060142320 Polymorphic forms of naltrexone |
| 06/29/2006 | CA2592407A1 Methods of treating pain |
| 06/22/2006 | WO2006064779A1 Indolomorphinan derivative having carboxy in 6'-position |
| 06/22/2006 | WO2005047291A9 Method for the catalytic production of hydrocodone and hydromorphone |
| 06/22/2006 | CA2590182A1 Indolomorphinan derivatives having carboxy at the 6'-position |
| 06/08/2006 | DE10081928B4 6-O-Acetylmorphin (6MAM)-Analoge Verbindungen, welche zur Verwendung in Immuntests geeignet sind, hiergegen gewonnene Antikörper, deren Herstellung sowie Reagentien und Reagenssysteme, die diese umfassen 6-O-acetylmorphine (6MAM) analogs compounds which are suitable for use in immunoassays, antibody obtained against this, their preparation as well as reagents and reagent systems which comprise these |
| 06/07/2006 | EP1664061A1 Process for the synthesis of morphinane compounds and intermediates thereof |
| 05/31/2006 | EP1660088A2 Pyridomorphinans, pyridazinomorphinans and use thereof |
| 05/26/2006 | WO2005113557A8 Method for the catalytic production of hydrocodone and hydromorphone |
| 05/25/2006 | US20060111383 Preparing a mixture comprising oxycodone and a solvent, adjusting the pH of the mixture to less than 6 and heating the mixture at the temperature of at least 55 degrees C for a period of at least 1 hour; and subsequently; exposing the mixture to hydrogenation reagents |
| 05/25/2006 | US20060111381 Amidine compounds |
| 05/24/2006 | EP1658293A1 A method of preparation of oxycodone |
| 05/24/2006 | EP1485051A4 Method of administering buprenorphine to treat depression |
| 05/23/2006 | CA2189140C New antagonist compounds |
| 05/18/2006 | WO2006052456A1 Method for separation and purification of hydrocodone by preparative chromatography |
| 05/18/2006 | CA2585533A1 Method for separation and purification of hydrocodone by preparative chromatography |
| 05/11/2006 | WO2006049248A1 Analgesic |
| 05/04/2006 | WO2005077957A3 Methods for making 3-o-protected morphinones and 3-o-protected morphinone dienol carboxylates |
| 05/04/2006 | US20060094741 Remedies for neuropathic pain and model animals of neuropathic pain |
| 05/02/2006 | CA2191843C The preparation of nalbuphine having low levels of beta-epimer |
| 04/12/2006 | CN1758912A Therapeutic agents for drug/substance dependence |
| 04/11/2006 | US7026134 Contacting the sample with the conjugate and an antibody capable of binding atleast one epitope of oxycodone and its metabolite, and detecting the bound conjugate |
| 04/06/2006 | WO2006035195A1 Preparation of opiate analgesics by reductive alkylation |
| 04/06/2006 | US20060074239 Method for the catalytic production of hydrocodone and hydromorphone |
| 04/04/2006 | US7022724 Cognition enhancing derivatives of isoxazole triazoloindane GABA-A α5 receptor subunit ligands |
| 03/30/2006 | WO2006034039A2 Substituted morphinans and methods of their use |
| 03/30/2006 | CA2597410A1 Substituted morphinans and methods of their use |
| 03/29/2006 | EP1638975A2 Method for preparing oxycodone |
| 03/23/2006 | US20060063792 Substituted morphinans and methods of their use |
| 03/16/2006 | WO2006029167A2 Treatment of diseases using nalmefene and its analgos |
| 03/16/2006 | CA2579378A1 Treatment of diseases using nalmefene and its analogs |
| 03/14/2006 | CA2380810C Pyridomorphinans and use thereof |
| 03/14/2006 | CA2241014C Morphine derivatives with analgesic activity |
| 03/07/2006 | US7008939 Use of weak opioids and mixed opioid agonists/antagonists for treatment of urinary incontinence |
| 03/02/2006 | US20060047119 Analgesics with use of treating pain and as immunomodulators and for treatment of drug dependence |
| 03/01/2006 | EP1628664A2 Polymorphic forms of naltrexone |
| 02/28/2006 | CA2144770C Brain cell protective agent |
| 02/23/2006 | US20060040970 Administering 4,5 alpha -epoxy-6 beta -(3,4-dihydro-2H-benzo[1,4]thiazino)-3-methoxy-17-methyl-morphinan; for urinary frequency, therapeutic or prophylactic effect and of which side effects are improved |
| 02/09/2006 | US20060030580 Contacting phenolic piperidines with opioid receptors; analgesics, anticonvulsants, antitussive agents; diarrhea, drug addiction |
| 02/08/2006 | EP1623703A1 Controlled release hydrocodone formulations |
| 02/02/2006 | US20060025434 Therapeutic agents for drug/substance dependence |
| 01/24/2006 | CA2143864C Morphinan derivatives and pharmaceutical use thereof |
| 01/19/2006 | US20060014771 Quaternizing a tertiary N-substituted morphinan alkaloid substrate such as naltrexone with an alkylating agent such as methyl bromide in an anhydrous aprotic dipolar solvent; separating a 3-alkoxymorphinan from a 3-hydroxymorphinan by forming a salt of the hydride with a strong base and precipitating it. |
| 01/12/2006 | US20060009479 Process for the synthesis of hydromorphone |
| 01/11/2006 | CN1720232A Tetandrine and tetrandrine compound, synthesis and application |
| 01/05/2006 | WO2005009377A3 Novel oral bioavailable prodrugs |
| 12/29/2005 | WO2005123743A1 Extraction of alkaloids from opium |
| 12/29/2005 | CA2569758A1 Extraction of alkaloids from opium |
| 12/28/2005 | EP1368023B1 Utilization of buprenorphine in urinary incontinence therapy |
| 12/28/2005 | EP1053238B1 Therapeutic compounds |
| 12/28/2005 | CN1233645C Novel oripavine derivative and its medical use |
| 12/21/2005 | CN1711270A Process for the preparation of quaternary n-alkyl morphinan alkaloid salts |
| 12/15/2005 | WO2005117589A1 Synthesis of metabolically stable analgesics, pain medications and other agents |
| 12/15/2005 | CA2568249A1 Synthesis of metabolically stable analgesics, pain medications and other agents |
| 12/07/2005 | EP1602374A1 Remedy for drug/substance dependence |
| 12/06/2005 | US6972332 Process for the production of opiates |
| 12/01/2005 | WO2005113557A1 Method for the catalytic production of hydrocodone and hydromorphone |
| 12/01/2005 | CA2544950A1 Method for the catalytic production of hydrocodone and hydromorphone |
| 11/30/2005 | CN1703416A Methods and compositions comprising nitric oxide donors and opioid analgesics |
| 11/30/2005 | CN1703415A Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group |
| 11/29/2005 | CA2247616C Morphine and diamorphine salts of anionic non-narcotic analgesics of the substituted carboxylic acid type |
| 11/24/2005 | US20050261500 methylating morphine in inert solvent in presence of alkaline ingedient, then recovering codeine as free base |
| 11/24/2005 | US20050261329 administering morphinan's such as 3-methoxy-17-allylmorphinan hydrobromide for prevention or treatment of viral infections, septic shock, organ damage, neurological and cardiovascular disorders, neurodegenerative diseases and cancers |
| 11/23/2005 | EP1467718B1 Method of treatment of a patient requiring analgesia |
| 11/22/2005 | CA2304722C Acidic addition salts of morphine alkaloids and the application thereof |
| 11/22/2005 | CA2261675C Preparation of narcotic analgesics |
| 11/02/2005 | CN1692117A Preparation of codeine from morphine |
| 10/27/2005 | WO2005100361A1 A METHOD OF PREPARATION OF 4,5α-EPOXY-6-OXOMORPHINAN DERIVATIVES |
| 10/27/2005 | WO2005100357A1 Mitotic kinesin inhibitors |
| 10/27/2005 | CA2561904A1 Mitotic kinesin inhibitors |
| 10/26/2005 | EP1504011B1 Microbial n- and o-demethylation of a thebaine derivative |
| 10/25/2005 | US6958398 Methods for making thebaine or its acid salts |
| 10/20/2005 | WO2005097801A1 Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone |
| 10/20/2005 | CA2774121A1 Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone |
| 10/20/2005 | CA2557845A1 Process for preparing, and composition and pharmaceutical dosage forms containing, an oxycodone salt having less than 25 ppm 14-hydroxycodeinone |
| 10/19/2005 | CN1684967A N-substituted hydromorphones and the use thereof |
| 10/13/2005 | WO2005094826A1 Anti-itching agent |
| 10/13/2005 | US20050228002 Anti proliferavtive agents; small molecule inhibitors of KSP(kinesin-related proteins); N-(3-aminopropyl)-N-[1-(3-benzyl-4-oxo-6,7,8 ,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-2-yl)propyl]-4-bromobenzamide |
| 10/06/2005 | US20050222188 comprising hydrogenating with a hydrogen donor and a catalyst under reflux |
| 09/29/2005 | US20050215556 Macrocyclic kinase inhibitors |
| 09/28/2005 | CN1675217A Oxycodone-hydrochloride polymorhs |
| 09/27/2005 | US6949645 methylation morphine using phenyltrimethylammonium chloride as alkylation agents, in the presence of inorganic phosphates, to form codeine or oripavine; purity; efficiency |
| 09/22/2005 | WO2005086960A2 Narcotic-nsaid ion pairs |
| 09/20/2005 | US6946556 Preparation of opioid analgesics by a one-pot process |
| 09/15/2005 | US20050203115 Narcotic-NSAID ion pairs |
| 09/07/2005 | CN1665819A Morphinan derivatives the quaternary ammonium salts thereof substituted in position 14, method for production and use thereof |
| 09/01/2005 | US20050192308 N-but-E-enyl norbuprenorphine and methods of use |
| 08/25/2005 | WO2005077957A2 Methods for making 3-o-protected morphinones and 3-o-protected morphinone dienol carboxylates |
| 08/25/2005 | CA2808199A1 Methods for making 3-o-protected morphinones and 3-o-protected morphinone dienol carboxylates |
| 08/18/2005 | US20050182258 Morphinan derivatives the quaternary ammonium salts thereof substituted in position 14, method for production and use thereof |